Implementation of QbD Approach to the Development of Chromatographic Methods for the Determination of Complete Impurity Profile of Substance on the Preclinical and Clinical Step of Drug Discovery Studies
Gurba-Bryśkiewicz, Lidia, Dawid, Urszula, Smuga, Damian A, Maruszak, Wioleta, Delis, Monika, Szymczak, Krzysztof, Stypik, Bartosz, Moroz, Aleksandra, Błocka, Aleksandra, Mroczkiewicz, Michał, Dubiel, Krzysztof, Wieczorek, Maciej
Published in International journal of molecular sciences (14.09.2022)
Published in International journal of molecular sciences (14.09.2022)
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Preclinical characterization of CPL302-253, a selective inhibitor of PI3Kδ, as the candidate for the inhalatory treatment and prevention of Asthma
Gunerka, Paweł, Gala, Kamila, Banach, Martyna, Dominowski, Jakub, Hucz-Kalitowska, Joanna, Mulewski, Krzysztof, Hajnal, Agnes, Mikus, Endre G., Smuga, Damian, Zagozda, Marcin, Dubiel, Krzysztof, Pieczykolan, Jerzy, Zygmunt, Beata M., Wieczorek, Maciej
Published in PloS one (23.07.2020)
Published in PloS one (23.07.2020)
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Do Small Molecules Activate the TrkB Receptor in the Same Manner as BDNF? Limitations of Published TrkB Low Molecular Agonists and Screening for Novel TrkB Orthosteric Agonists
Pankiewicz, Piotr, Szybiński, Marcin, Kisielewska, Katarzyna, Gołębiowski, Filip, Krzemiński, Patryk, Rutkowska-Włodarczyk, Izabela, Moszczyński-Pętkowski, Rafał, Gurba-Bryśkiewicz, Lidia, Delis, Monika, Mulewski, Krzysztof, Smuga, Damian, Dominowski, Jakub, Janusz, Artur, Górka, Michał, Abramski, Krzysztof, Napiórkowska, Agnieszka, Nowotny, Marcin, Dubiel, Krzysztof, Kalita, Katarzyna, Wieczorek, Maciej, Pieczykolan, Jerzy, Matłoka, Mikołaj
Published in Pharmaceuticals (Basel, Switzerland) (21.07.2021)
Published in Pharmaceuticals (Basel, Switzerland) (21.07.2021)
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Journal Article
Syntheses and antiproliferative activities of novel phosphatidylcholines containing dehydroepiandrosterone moieties
Kłobucki, Marek, Grudniewska, Aleksandra, Smuga, Damian A., Smuga, Małgorzata, Jarosz, Joanna, Wietrzyk, Joanna, Maciejewska, Gabriela, Wawrzeńczyk, Czesław
Published in Steroids (01.02.2017)
Published in Steroids (01.02.2017)
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Design, Synthesis, and Development of Pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part II—Benzimidazole Derivatives
Stypik, Mariola, Michałek, Stanisław, Orłowska, Nina, Zagozda, Marcin, Dziachan, Maciej, Banach, Martyna, Turowski, Paweł, Gunerka, Paweł, Zdżalik-Bielecka, Daria, Stańczak, Aleksandra, Kędzierska, Urszula, Mulewski, Krzysztof, Smuga, Damian, Maruszak, Wioleta, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Pietruś, Wojciech, Ochal, Zbigniew, Mach, Mateusz, Zygmunt, Beata, Pieczykolan, Jerzy, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Pharmaceuticals (Basel, Switzerland) (27.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (27.07.2022)
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Preclinical characterization of CPL304110 as a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3 for gastric, bladder, and squamous cell lung cancer
Popiel, Delfina, Stańczak, Aleksandra, Skupińska, Monika, Mikołajczyk, Agata, Stańczak, Paulina, Mituła, Filip, Hucz-Kalitowska, Joanna, Jastrzębska, Kinga, Smuga, Damian, Dominowski, Jakub, Delis, Monika, Mulewski, Krzysztof, Pietruś, Wojciech, Zdżalik-Bielecka, Daria, Dzwonek, Karolina, Lamparska-Przybysz, Monika, Yamani, Abdellah, Olejkowska, Patrycja, Piórkowska, Natalia, Dubiel, Krzysztof, Wieczorek, Maciej, Pieczykolan, Jerzy
Published in Frontiers in oncology (2023)
Published in Frontiers in oncology (2023)
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Journal Article
Design, Synthesis, and Development of pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part I—Indole Derivatives
Stypik, Mariola, Zagozda, Marcin, Michałek, Stanisław, Dymek, Barbara, Zdżalik-Bielecka, Daria, Dziachan, Maciej, Orłowska, Nina, Gunerka, Paweł, Turowski, Paweł, Hucz-Kalitowska, Joanna, Stańczak, Aleksandra, Stańczak, Paulina, Mulewski, Krzysztof, Smuga, Damian, Stefaniak, Filip, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Ochal, Zbigniew, Mach, Mateusz, Dzwonek, Karolina, Lamparska-Przybysz, Monika, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Pharmaceuticals (Basel, Switzerland) (30.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (30.07.2022)
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Journal Article
Synthesis of dehydroepiandrosterone analogues modified with phosphatidic acid moiety
Smuga, Damian A., Smuga, Małgorzata, Świzdor, Alina, Panek, Anna, Wawrzeńczyk, Czesław
Published in Steroids (12.12.2010)
Published in Steroids (12.12.2010)
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CPL207280, a Novel G Protein–Coupled Receptor 40/Free Fatty Acid Receptor 1–Specific Agonist, Shows a Favorable Safety Profile and Exerts Antidiabetic Effects in Type 2 Diabetic Animals
Bazydlo-Guzenda, Katarzyna, Buda, Pawel, Matloka, Mikolaj, Mach, Mateusz, Stelmach, Filip, Dzida, Radoslaw, Smuga, Damian, Hucz-Kalitowska, Joanna, Teska-Kaminska, Malgorzata, Vialichka, Varvara, Dubiel, Krzysztof, Kaminska, Bozena, Wieczorek, Maciej, Pieczykolan, Jerzy
Published in Molecular pharmacology (01.10.2021)
Published in Molecular pharmacology (01.10.2021)
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Journal Article
Quality by Design as a Strategy for Tuning Lipid Nanoparticle Formulations for RNA Delivery
Gurba-Bryśkiewicz, Lidia, Maruszak, Wioleta, Smuga, Damian A, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Biomedicines (01.10.2023)
Published in Biomedicines (01.10.2023)
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Journal Article
Discovery and development of CPL207280 as new GPR40/FFA1 agonist
Mach, Mateusz, Bazydło-Guzenda, Katarzyna, Buda, Paweł, Matłoka, Mikołaj, Dzida, Radosław, Stelmach, Filip, Gałązka, Kinga, Wąsińska-Kałwa, Małgorzata, Smuga, Damian, Hołowińska, Dagmara, Dawid, Urszula, Gurba-Bryśkiewicz, Lidia, Wiśniewski, Krzysztof, Dubiel, Krzysztof, Pieczykolan, Jerzy, Wieczorek, Maciej
Published in European journal of medicinal chemistry (15.12.2021)
Published in European journal of medicinal chemistry (15.12.2021)
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Synthesis and characterization of novel classes of PDE10A inhibitors - 1H-1,3-benzodiazoles and imidazo[1,2-a]pyrimidines
Moszczyński-Pętkowski, Rafał, Majer, Jakub, Borkowska, Małgorzata, Bojarski, Łukasz, Janowska, Sylwia, Matłoka, Mikołaj, Stefaniak, Filip, Smuga, Damian, Bazydło, Katarzyna, Dubiel, Krzysztof, Wieczorek, Maciej
Published in European journal of medicinal chemistry (15.07.2018)
Published in European journal of medicinal chemistry (15.07.2018)
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An LC method for the analysis of phosphatidylcholine hydrolysis products and its application to the monitoring of the acyl migration process
Kiełbowicz, Grzegorz, Smuga, Damian, Gładkowski, Witold, Chojnacka, Anna, Wawrzeńczyk, Czesław
Published in Talanta (Oxford) (30.05.2012)
Published in Talanta (Oxford) (30.05.2012)
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Design, Synthesis, and Development of Pyrazolo[1,5-Ia/I]pyrimidine Derivatives as a Novel Series of Selective PI3KIδ/I Inhibitors: Part II—Benzimidazole Derivatives
Stypik, Mariola, Michałek, Stanisław, Orłowska, Nina, Zagozda, Marcin, Dziachan, Maciej, Banach, Martyna, Turowski, Paweł, Gunerka, Paweł, Zdżalik-Bielecka, Daria, Stańczak, Aleksandra, Kędzierska, Urszula, Mulewski, Krzysztof, Smuga, Damian, Maruszak, Wioleta, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Pietruś, Wojciech, Ochal, Zbigniew, Mach, Mateusz, Zygmunt, Beata, Pieczykolan, Jerzy, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2022)
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Journal Article
Design, Synthesis, and Development of pyrazolo[1,5-Ia/I]pyrimidine Derivatives as a Novel Series of Selective PI3KIδ/I Inhibitors: Part I—Indole Derivatives
Stypik, Mariola, Zagozda, Marcin, Michałek, Stanisław, Dymek, Barbara, Zdżalik-Bielecka, Daria, Dziachan, Maciej, Orłowska, Nina, Gunerka, Paweł, Turowski, Paweł, Hucz-Kalitowska, Joanna, Stańczak, Aleksandra, Stańczak, Paulina, Mulewski, Krzysztof, Smuga, Damian, Stefaniak, Filip, Gurba-Bryśkiewicz, Lidia, Leniak, Arkadiusz, Ochal, Zbigniew, Mach, Mateusz, Dzwonek, Karolina, Lamparska-Przybysz, Monika, Dubiel, Krzysztof, Wieczorek, Maciej
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2022)
Published in Pharmaceuticals (Basel, Switzerland) (01.07.2022)
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GPR40 작용제로서 3-페닐-4-헥신산 유도체
MACH MATEUSZ, STELMACH FILIP, DZIDA RADOSLAW, BAZYDLO KATARZYNA, MATLOKA MIKOLAJ, WIECZOREK MACIEJ, PIECZYKOLAN JERZY, DUBIEL KRZYSZTOF, SMUGA DAMIAN
Year of Publication 17.09.2020
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Year of Publication 17.09.2020
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