Reduced Maximal Inhibition in Phenotypic Susceptibility Assays Indicates that Viral Strains Resistant to the CCR5 Antagonist Maraviroc Utilize Inhibitor-Bound Receptor for Entry
WESTBY, Mike, SMITH-BURCHNELL, Caroline, MORI, Julie, LEWIS, Marilyn, MOSLEY, Nichael, STOCKDALE, Mark, DORR, Patrick, CIARAMELLA, Giuseppe, PERROS, Manos
Published in Journal of Virology (01.03.2007)
Published in Journal of Virology (01.03.2007)
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Maraviroc (UK-427,857), a Potent, Orally Bioavailable, and Selective Small-Molecule Inhibitor of Chemokine Receptor CCR5 with Broad-Spectrum Anti-Human Immunodeficiency Virus Type 1 Activity
DORR, Patrick, WESTBY, Mike, WEBSTER, Rob, ARMOUR, Duncan, PRICE, David, STAMMEN, Blanda, WOOD, Anthony, PERROS, Manos, DOBBS, Susan, GRIFFIN, Paul, IRVINE, Becky, MACARTNEY, Malcolm, MORI, Julie, RICKETT, Graham, SMITH-BURCHNELL, Caroline, NAPIER, Carolyn
Published in Antimicrobial Agents and Chemotherapy (01.11.2005)
Published in Antimicrobial Agents and Chemotherapy (01.11.2005)
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Lersivirine, a Nonnucleoside Reverse Transcriptase Inhibitor with Activity against Drug-Resistant Human Immunodeficiency Virus Type 1
Corbau, Romuald, Mori, Julie, Phillips, Chris, Fishburn, Lesley, Martin, Alex, Mowbray, Charles, Panton, Wendy, Smith-Burchnell, Caroline, Thornberry, Adele, Ringrose, Heather, Knöchel, Thorsten, Irving, Steve, Westby, Mike, Wood, Anthony, Perros, Manos
Published in Antimicrobial Agents and Chemotherapy (01.10.2010)
Published in Antimicrobial Agents and Chemotherapy (01.10.2010)
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Knockdown of USP18 Increases Alpha 2a Interferon Signaling and Induction of Interferon-Stimulating Genes but Does Not Increase Antiviral Activity in Huh7 Cells
MURRAY, E. J, BURDEN, Frances, HORSCROFT, Nigel, SMITH-BURCHNELL, Caroline, WESTBY, Mike
Published in Antimicrobial Agents and Chemotherapy (01.09.2011)
Published in Antimicrobial Agents and Chemotherapy (01.09.2011)
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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile-Part 1
Tran, Thien Duc, Wakenhut, Florian, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Brimage, Rebecca A., Halstead, Rebecca, Glen, Rebecca, Wilson, Craig P., Adam, Fiona, Hay, Duncan, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C., Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C.
Published in ChemMedChem (01.07.2014)
Published in ChemMedChem (01.07.2014)
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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile-Part 2
Wakenhut, Florian, Tran, Thien Duc, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Stonehouse, David, Cheung, Kathy, Wybrow, Robert, Daverio, Felice, Crook, Samuel, Statham, Keith, Leese, David, Stead, Darren, Adam, Fiona, Hay, Duncan, Roberts, Lee R., Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C., Goetz, Gilles H., Che, Ye, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C.
Published in ChemMedChem (01.07.2014)
Published in ChemMedChem (01.07.2014)
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In Vitro Characterization of the Activity of PF-05095808, a Novel Biological Agent for Hepatitis C Virus Therapy
Lavender, Helen, Brady, Kevin, Burden, Frances, Delpuech-Adams, Oona, Denise, Hubert, Palmer, Amy, Perkins, Hannah, Savic, Boris, Scott, Sarah, Smith-Burchnell, Caroline, Troke, Phil, Wright, J. Fraser, Suhy, David, Corbau, Romu
Published in Antimicrobial Agents and Chemotherapy (01.03.2012)
Published in Antimicrobial Agents and Chemotherapy (01.03.2012)
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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile--Part1
Tran, Thien Duc, Wakenhut, Florian, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Brimage, Rebecca A, Halstead, Rebecca, Glen, Rebecca, Wilson, Craig P, Adam, Fiona, Hay, Duncan, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C
Published in ChemMedChem (01.07.2014)
Published in ChemMedChem (01.07.2014)
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The Discovery of Potent Nonstructural Protein 5A (NS5A) Inhibitors with a Unique Resistance Profile--Part2
Wakenhut, Florian, Tran, Thien Duc, Pickford, Chris, Shaw, Stephen, Westby, Mike, Smith-Burchnell, Caroline, Watson, Lesa, Paradowski, Michael, Milbank, Jared, Stonehouse, David, Cheung, Kathy, Wybrow, Robert, Daverio, Felice, Crook, Samuel, Statham, Keith, Leese, David, Stead, Darren, Adam, Fiona, Hay, Duncan, Roberts, Lee R, Chiva, Jean-Yves, Nichols, Carly, Blakemore, David C, Goetz, Gilles H, Che, Ye, Gardner, Iain, Dayal, Satish, Pike, Andrew, Webster, Rob, Pryde, David C
Published in ChemMedChem (01.07.2014)
Published in ChemMedChem (01.07.2014)
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Knockdown of USP18 increases α 2a interferon signaling and induction of interferon-stimulating genes but does not increase antiviral activity in Huh7 cells
Murray, E J, Burden, Frances, Horscroft, Nigel, Smith-Burchnell, Caroline, Westby, Mike
Published in Antimicrobial agents and chemotherapy (01.09.2011)
Published in Antimicrobial agents and chemotherapy (01.09.2011)
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Identification of HCV Inhibitors from a Cell-Based Sub-Genomic Replicon Screen
Pryde, David C., Tran, Thien-Duc, Gardner, Mark, Pickford, Chris, Shaw, Stephen M., Westby, Mike, Parkinson, Tanya, Smith-Burchnell, Caroline, Webster, Rob, Dayal, Satish
Published in Open journal of medicinal chemistry (01.03.2013)
Published in Open journal of medicinal chemistry (01.03.2013)
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HIV-1 proteinase is required for synthesis of pro-viral DNA
Baboonian, Christina, Dalgleish, Angus, Bountiff, Lynne, Gross, Jackie, Oroszlan, Stephen, Rickett, Graham, Smith-Burchnell, Caroline, Troke, Peter, Merson, James
Published in Biochemical and biophysical research communications (30.08.1991)
Published in Biochemical and biophysical research communications (30.08.1991)
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Use of T cell cloning to detect in vivo mutations induced by cyclophosphamide
Palmer, R G, Smith-Burchnell, C A, Pelton, B K, Hylton, W, Denman, A M
Published in Arthritis and rheumatism (01.06.1988)
Published in Arthritis and rheumatism (01.06.1988)
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