Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties
Pinto, Donald J.P., Smallheer, Joanne M., Corte, James R., Austin, Erin J.D., Wang, Cailan, Fang, Tianan, Smith, Leon M., Rossi, Karen A., Rendina, Alan R., Bozarth, Jeffrey M., Zhang, Ge, Wei, Anzhi, Ramamurthy, Vidhyashankar, Sheriff, Steven, Myers, Joseph E., Morin, Paul E., Luettgen, Joseph M., Seiffert, Dietmar A., Quan, Mimi L., Wexler, Ruth R.
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Get full text
Journal Article
Macrocycles with hetrocyclic p2' groups as factor xia inhibitors
YANG Wu, DILGER Andrew K, CORTE James R, FANG Tianan, WEXLER Ruth R, SMITH Leon M. II, WANG Yufeng, ORWAT Michael J, DE LUCCA Indawati, PINTO Donald J. P, PABBISETTY Kumar Balashanmuga, EWING William R, ZHU Yeheng
Year of Publication 01.03.2024
Get full text
Year of Publication 01.03.2024
Patent
Pyrimidinones as factor xia inhibitors
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pinto, Donald J.p, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, De Lucca, Indawati, Wexler, Ruth R, Smith Ii, Leon M, Zhu, Yeheng
Year of Publication 26.01.2024
Get full text
Year of Publication 26.01.2024
Patent
Pyrimidinones as factor xia inhibitors
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pinto, Donald J.p, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, De Lucca, Indawati, Wexler, Ruth R, Smith Ii, Leon M, Zhu, Yeheng
Year of Publication 26.01.2024
Get full text
Year of Publication 26.01.2024
Patent
Macrocycles with hetrocyclic p2' groups as factor xia inhibitors
YANG Wu, DILGER Andrew K, CORTE James R, FANG Tianan, WEXLER Ruth R, SMITH Leon M. II, WANG Yufeng, ORWAT Michael J, DE LUCCA Indawati, PINTO Donald J. P, PABBISETTY Kumar Balashanmuga, EWING William R, ZHU Yeheng
Year of Publication 01.11.2023
Get full text
Year of Publication 01.11.2023
Patent
Macrocycles with hetrocyclic p2' groups as factor xia inhibitors
YANG Wu, DILGER Andrew K, CORTE James R, FANG Tianan, WEXLER Ruth R, SMITH Leon M. II, WANG Yufeng, ORWAT Michael J, DE LUCCA Indawati, PINTO Donald J. P, PABBISETTY Kumar Balashanmuga, EWING William R, ZHU Yeheng
Year of Publication 01.11.2023
Get full text
Year of Publication 01.11.2023
Patent
Macrocycles with hetrocyclic p2' groups as factor xia inhibitors
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pinto, Donald J.p, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, De Lucca, Indawati, Wexler, Ruth R, Smith, Leon M. Ii, Zhu, Yeheng
Year of Publication 28.04.2023
Get full text
Year of Publication 28.04.2023
Patent
Structure-based design of inhibitors of coagulation factor XIa with novel P1 moieties
Pinto, Donald J. P., Smallheer, Joanne M., Corte, James R., Austin, Erin J. D., Wang, Cailan, Fang, Tianan, Smith, II, Leon M., Rossi, Karen A., Rendina, Alan R., Bozarth, Jeffrey M., Zhang, Ge, Wei, Anzhi, Ramamurthy, Vidhyashankar, Sheriff, Steven, Myers, Jr., Joseph E., Morin, Paul E., Luettgen, Joseph M., Seiffert, Dietmar A., Quan, Mimi L., Wexler, Ruth R.
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Get full text
Published in Bioorganic & medicinal chemistry letters (01.04.2015)
Journal Article
Macrocycles with hetrocyclic p2' groups as factor xia inhibitors
Ewing, William R, Wang, Yufeng, Fang, Tianan, Pinto, Donald J.p, Pabbisetty, Kumar Balashanmuga, Corte, James R, Yang, Wu, Orwat, Michael J, Dilger, Andrew K, De Lucca, Indawati, Wexler, Ruth R, Smith, Leon M. Ii, Zhu, Yeheng
Year of Publication 31.03.2023
Get full text
Year of Publication 31.03.2023
Patent
Macrocycles with hetrocyclic p2' groups as factor xia inhibitors
YANG Wu, DILGER Andrew K, CORTE James R, FANG Tianan, WEXLER Ruth R, SMITH Leon M. II, WANG Yufeng, ORWAT Michael J, DE LUCCA Indawati, PINTO Donald J. P, PABBISETTY Kumar Balashanmuga, EWING William R, ZHU Yeheng
Year of Publication 01.02.2023
Get full text
Year of Publication 01.02.2023
Patent
MACROCYCLES WITH HETEROCYCLIC P2' GROUPS AS FACTOR XIA INHIBITORS
ZHU, Yeheng, ORWAT, Michael J, PABBISETTY, Kumar Balashanmuga, CORTE, James R, SMITH, Leon M. II, YANG, Wu, DILGER, Andrew K, WANG, Yufeng, PINTO, Donald J.P, FANG, Tianan, DE LUCCA, Indawati, EWING, William R, WEXLER, Ruth R
Year of Publication 27.04.2022
Get full text
Year of Publication 27.04.2022
Patent
MACROCYCLES WITH HETROCYCLIC P2' GROUPS AS FACTOR XIA INHIBITORS
ZHU, Yeheng, PINTO, Donald J. P, ORWAT, Michael J, PABBISETTY, Kumar Balashanmuga, CORTE, James R, SMITH, Leon M. II, YANG, Wu, DILGER, Andrew K, WANG, Yufeng, FANG, Tianan, DE LUCCA, Indawati, EWING, William R, WEXLER, Ruth R
Year of Publication 21.04.2022
Get full text
Year of Publication 21.04.2022
Patent
MACROCYCLES WITH HETEROCYCLIC P2' GROUPS AS FACTOR XIA INHIBITORS
ZHU, Yeheng, PINTO, Donald J. P, ORWAT, Michael J, PABBISETTY, Kumar Balashanmuga, CORTE, James R, SMITH, Leon M. II, YANG, Wu, DILGER, Andrew K, WANG, Yufeng, FANG, Tianan, DE LUCCA, Indawati, EWING, William R, WEXLER, Ruth R
Year of Publication 25.08.2021
Get full text
Year of Publication 25.08.2021
Patent
SUBSTITUTED TETRAHYDROISOQUINOLINE COMPOUNDS AS FACTOR XIA INHIBITORS
MICHAEL J. ORWAT, SHEFALI SRIVASTAVA, DONALD J.P. PINTO, LEON M. SMITH II
Year of Publication 26.05.2017
Get full text
Year of Publication 26.05.2017
Patent
Compostos de tetra-hidroisoquinolina substituídos como inibidores do fator xia
MICHAEL J. ORWAT, SRIVASTAVA SHEFALI, LEON M. SMITH II, DONALD J. P. PINTO
Year of Publication 14.12.2021
Get full text
Year of Publication 14.12.2021
Patent
MACROCYCLES WITH HETROCYCLIC P2' GROUPS AS FACTOR XIA INHIBITORS
ZHU, Yeheng, PINTO, Donald J. P, ORWAT, Michael J, PABBISETTY, Kumar Balashanmuga, CORTE, James R, SMITH, Leon M. II, YANG, Wu, DILGER, Andrew K, WANG, Yufeng, FANG, Tianan, DE LUCCA, Indawati, EWING, William R, WEXLER, Ruth R
Year of Publication 30.10.2019
Get full text
Year of Publication 30.10.2019
Patent
Spiroheptane salicylamides and related compounds as inhibitors of rock
SMITH, LEON M. II, PANDA, MANORANJAN, LADZIATA, VLADIMIR, GLUNZ, PETER W
Year of Publication 11.06.2021
Get full text
Year of Publication 11.06.2021
Patent
MACROCYCLES WITH HETROCYCLIC P2' GROUPS AS FACTOR XIA INHIBITORS
ZHU, Yeheng, PINTO, Donald J. P, ORWAT, Michael J, PABBISETTY, Kumar Balashanmuga, CORTE, James R, SMITH, Leon M. II, YANG, Wu, DILGER, Andrew K, WANG, Yufeng, FANG, Tianan, DE LUCCA, Indawati, EWING, William R, WEXLER, Ruth R
Year of Publication 28.02.2019
Get full text
Year of Publication 28.02.2019
Patent
Espiroheptano salicilamidas e compostos relacionados como inibidores de rock, composição farmacêutica e uso dos mesmos
PANDA MANORANJAN, MICHAEL J. ORWAT, LADZIATA VLADIMIR, KUMAR BALASHANMUGA PABBISETTY, PETER W. GLUNZ, SCOTT A. SHAW, LEON M. SMITH II, YANG WU, DONALD J. P. PINTO, DELUCCA INDAWATI, ANDREW K. DILGER
Year of Publication 19.12.2023
Get full text
Year of Publication 19.12.2023
Patent
MACROCYCLES WITH HETROCYCLIC P2' GROUPS AS FACTOR XIA INHIBITORS
ZHU, Yeheng, PINTO, Donald J. P, ORWAT, Michael J, PABBISETTY, Kumar Balashanmuga, CORTE, James R, SMITH, Leon M. II, YANG, Wu, DILGER, Andrew K, WANG, Yufeng, FANG, Tianan, DE LUCCA, Indawati, EWING, William R, WEXLER, Ruth R
Year of Publication 24.10.2018
Get full text
Year of Publication 24.10.2018
Patent