A Vaccinia-based system for directed evolution of GPCRs in mammalian cells
Klenk, Christoph, Scrivens, Maria, Niederer, Anina, Shi, Shuying, Mueller, Loretta, Gersz, Elaine, Zauderer, Maurice, Smith, Ernest S., Strohner, Ralf, Plückthun, Andreas
Published in Nature communications (30.03.2023)
Published in Nature communications (30.03.2023)
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Semaphorin 4D is upregulated in neurons of diseased brains and triggers astrocyte reactivity
Evans, Elizabeth E, Mishra, Vikas, Mallow, Crystal, Gersz, Elaine M, Balch, Leslie, Howell, Alan, Reilly, Christine, Smith, Ernest S, Fisher, Terrence L, Zauderer, Maurice
Published in Journal of neuroinflammation (06.08.2022)
Published in Journal of neuroinflammation (06.08.2022)
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SEMA4D compromises blood–brain barrier, activates microglia, and inhibits remyelination in neurodegenerative disease
Smith, Ernest S, Jonason, Alan, Reilly, Christine, Veeraraghavan, Janaki, Fisher, Terrence, Doherty, Michael, Klimatcheva, Ekaterina, Mallow, Crystal, Cornelius, Chad, Leonard, John E, Marchi, Nicola, Janigro, Damir, Argaw, Azeb Tadesse, Pham, Trinh, Seils, Jennifer, Bussler, Holm, Torno, Sebold, Kirk, Renee, Howell, Alan, Evans, Elizabeth E, Paris, Mark, Bowers, William J, John, Gareth, Zauderer, Maurice
Published in Neurobiology of disease (2015)
Published in Neurobiology of disease (2015)
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Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease
Southwell, Amber L, Franciosi, Sonia, Villanueva, Erika B, Xie, Yuanyun, Winter, Laurie A, Veeraraghavan, Janaki, Jonason, Alan, Felczak, Boguslaw, Zhang, Weining, Kovalik, Vlad, Waltl, Sabine, Hall, George, Pouladi, Mahmoud A, Smith, Ernest S, Bowers, William J, Zauderer, Maurice, Hayden, Michael R
Published in Neurobiology of disease (01.04.2015)
Published in Neurobiology of disease (01.04.2015)
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CXCL13 antibody for the treatment of autoimmune disorders
Klimatcheva, Ekaterina, Pandina, Tracy, Reilly, Christine, Torno, Sebold, Bussler, Holm, Scrivens, Maria, Jonason, Alan, Mallow, Crystal, Doherty, Michael, Paris, Mark, Smith, Ernest S, Zauderer, Maurice
Published in BMC immunology (12.02.2015)
Published in BMC immunology (12.02.2015)
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A High-Affinity Fully Human Anti–IL-6 mAb, 1339, for the Treatment of Multiple Myeloma
FULCINITI, Mariateresa, HIDESHIMA, Teru, TAI, Yu-Tzu, TASSONE, Pierfrancesco, ANDERSON, Kenneth C, MUNSHI, Nikhil C, VERMOT-DESROCHES, Claudine, POZZI, Samantha, NANJAPPA, Puru, ZHENXIN SHEN, PATEL, Nipun, SMITH, Ernest S, WEI WANG, PRABHALA, Rao
Published in Clinical cancer research (01.12.2009)
Published in Clinical cancer research (01.12.2009)
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Use of poxvirus display to select antibodies specific for complex membrane antigens
Smith, Ernest S., Balch, Leslie A., Scrivens, Maria, Shi, Shuying, Wang, Wei, Harvey, Caroline D., Cornelison, Angelica A., Gil-Moore, Malgorzata, Kirk, Renee A., Mueller, Loretta L., Hall, Richard L., Howell, Alan P., Reilly, Christine A., Mayer, Jessica M., Murante, Francis G., Viggiani, Kari A, Gersz, Elaine M., Bussler, Holm, Keefe, Madeleine R., Evans, Elizabeth E., Paris, Mark J., Zauderer, Maurice
Published in mAbs (31.12.2023)
Published in mAbs (31.12.2023)
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Generation and preclinical characterization of an antibody specific for SEMA4D
Fisher, Terrence L, Reilly, Christine A, Winter, Laurie A, Pandina, Tracy, Jonason, Alan, Scrivens, Maria, Balch, Leslie, Bussler, Holm, Torno, Sebold, Seils, Jennifer, Mueller, Loretta, Huang, He, Klimatcheva, Ekaterina, Howell, Alan, Kirk, Renee, Evans, Elizabeth, Paris, Mark, Leonard, John E, Smith, Ernest S, Zauderer, Maurice
Published in mAbs (01.01.2016)
Published in mAbs (01.01.2016)
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Immunomodulation of the tumor microenvironment by neutralization of Semaphorin 4D
Evans, Elizabeth E, Paris, Mark, Smith, Ernest S, Zauderer, Maurice
Published in Oncoimmunology (02.12.2015)
Published in Oncoimmunology (02.12.2015)
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C35 (C17orf37) is a novel tumor biomarker abundantly expressed in breast cancer
Evans, Elizabeth E, Henn, Alicia D, Jonason, Alan, Paris, Mark J, Schiffhauer, Linda M, Borrello, Melinda A, Smith, Ernest S, Sahasrabudhe, Deepak M, Zauderer, Maurice
Published in Molecular cancer therapeutics (01.11.2006)
Published in Molecular cancer therapeutics (01.11.2006)
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Pepinemab antibody blockade of SEMA4D in early Huntington’s disease: a randomized, placebo-controlled, phase 2 trial
Feigin, Andrew, Evans, Elizabeth E., Fisher, Terrence L., Leonard, John E., Smith, Ernest S., Reader, Alisha, Mishra, Vikas, Manber, Richard, Walters, Kimberly A., Kowarski, Lisa, Oakes, David, Siemers, Eric, Kieburtz, Karl D., Zauderer, Maurice
Published in Nature medicine (01.10.2022)
Published in Nature medicine (01.10.2022)
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Publisher Correction: Pepinemab antibody blockade of SEMA4D in early Huntington’s disease: a randomized, placebo-controlled, phase 2 trial
Feigin, Andrew, Evans, Elizabeth E., Fisher, Terrence L., Leonard, John E., Smith, Ernest S., Reader, Alisha, Mishra, Vikas, Manber, Richard, Walters, Kimberly A., Kowarski, Lisa, Oakes, David, Siemers, Eric, Kieburtz, Karl D., Zauderer, Maurice
Published in Nature medicine (01.02.2024)
Published in Nature medicine (01.02.2024)
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Antibody Blockade of Semaphorin 4D Promotes Immune Infiltration into Tumor and Enhances Response to Other Immunomodulatory Therapies
Evans, Elizabeth E, Jonason, Jr, Alan S, Bussler, Holm, Torno, Sebold, Veeraraghavan, Janaki, Reilly, Christine, Doherty, Michael A, Seils, Jennifer, Winter, Laurie A, Mallow, Crystal, Kirk, Renee, Howell, Alan, Giralico, Susan, Scrivens, Maria, Klimatcheva, Katya, Fisher, Terrence L, Bowers, William J, Paris, Mark, Smith, Ernest S, Zauderer, Maurice
Published in Cancer immunology research (01.06.2015)
Published in Cancer immunology research (01.06.2015)
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Abstract 4888: Antibody blockade of semaphorin 4D breaks down stromal barriers to enhance tumoricidal immune infiltration, supporting rational immunotherapy combinations
Evans, Elizabeth E., Bussler, Holm, Torno, Sebold, Mallow, Crystal, Reilly, Christine, Scrivens, Maria, Klimatcheva, Ekaterina, Winter, Laurie A., Kirk, Renee, Howell, Alan, Balch, Leslie, Leonard, John E., Paris, Mark, Fisher, Terrence L., Hu-Lieskovan, Siwen, Ribas, Antoni, Smith, Ernest S., Zauderer, Maurice
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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