Search Results - "SMITH, Emilie D" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents

Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents

by Huang, Kenneth H, Veal, James M, Fadden, R. Patrick, Rice, John W, Eaves, Jeron, Strachan, Jon-Paul, Barabasz, Amy F, Foley, Briana E, Barta, Thomas E, Ma, Wei, Silinski, Melanie A, Hu, Mei, Partridge, Jeffrey M, Scott, Anisa, DuBois, Laura G, Freed, Tiffany, Steed, Paul M, Ommen, Andy J, Smith, Emilie D, Hughes, Philip F, Woodward, Angela R, Hanson, Gunnar J, McCall, W. Stephen, Markworth, Christopher J, Hinkley, Lindsay, Jenks, Matthew, Geng, Lifeng, Lewis, Meredith, Otto, James, Pronk, Bert, Verleysen, Katleen, Hall, Steven E
Published in Journal of medicinal chemistry (23.07.2009)

Get full text

Journal Article

Synthesis of C-4 Substituted Nicotine Derivatives via an N-Acylpyridinium Salt of (S)-Nicotine

Synthesis of C-4 Substituted Nicotine Derivatives via an N-Acylpyridinium Salt of (S)-Nicotine

by Comins, Daniel L, King, Laura S, Smith, Emilie D, Février, Florence C
Published in Organic letters (27.10.2005)

Get full text

Journal Article

Regioselective C-2 and C-6 Substitution of (S)-Nicotine and Nicotine Derivatives

Regioselective C-2 and C-6 Substitution of (S)-Nicotine and Nicotine Derivatives

by Février, Florence C, Smith, Emilie D, Comins, Daniel L
Published in Organic letters (24.11.2005)

Get full text

Journal Article

Synthesis of Nicotine Derivatives via Reductive Disilylation of (S)-Nicotine

Synthesis of Nicotine Derivatives via Reductive Disilylation of (S)-Nicotine

by Smith, Emilie D, Février, Florence C, Comins, Daniel L
Published in Organic letters (19.01.2006)

Get full text

Journal Article

Design, synthesis and biological evaluation of renin inhibitors guided by simulated annealing of chemical potential simulations

Design, synthesis and biological evaluation of renin inhibitors guided by simulated annealing of chemical potential simulations

by Cloudsdale, Ian S., Dickson, John K., Barta, Thomas E., Grella, Brian S., Smith, Emilie D., Kulp, John L., Guarnieri, Frank, Kulp, John L.
Published in Bioorganic & medicinal chemistry (01.08.2017)

Get full text

Journal Article

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90

by Huang, Kenneth H., Barta, Thomas E., Rice, John W., Smith, Emilie D., Ommen, Andy J., Ma, Wei, Veal, James M., Fadden, R. Patrick, Barabasz, Amy F., Foley, Briana E., Hughes, Philip F., Hanson, Gunnar J., Markworth, Christopher J., Silinski, Melanie, Partridge, Jeffrey M., Steed, Paul M., Hall, Steven E.
Published in Bioorganic & medicinal chemistry letters (01.04.2012)

Get full text

Journal Article

A six-step synthesis of ( S)-5-ethenyl-3-(1-methyl-2-pyrrolidinyl)pyridine (SIB-1508Y) from ( S)-nicotine

A six-step synthesis of ( S)-5-ethenyl-3-(1-methyl-2-pyrrolidinyl)pyridine (SIB-1508Y) from ( S)-nicotine

by Comins, Daniel L., Smith, Emilie D.
Published in Tetrahedron letters (27.02.2006)

Get full text

Journal Article

Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90

Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90

by Fadden, Patrick, Huang, Kenneth H., Veal, James M., Steed, Paul M., Barabasz, Amy F., Foley, Briana, Hu, Mei, Partridge, Jeffrey M., Rice, John, Scott, Anisa, Dubois, Laura G., Freed, Tiffany A., Silinski, Melanie A. Rehder, Barta, Thomas E., Hughes, Philip F., Ommen, Andy, Ma, Wei, Smith, Emilie D., Spangenberg, Angela Woodward, Eaves, Jeron, Hanson, Gunnar J., Hinkley, Lindsay, Jenks, Matthew, Lewis, Meredith, Otto, James, Pronk, Gijsbertus J., Verleysen, Katleen, Haystead, Timothy A., Hall, Steven E.
Published in Chemistry & biology (30.07.2010)

Get full text

Journal Article

A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay

A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay

by SMITH, Emilie D, ARIANE VINSON, N, DESONG ZHONG, BERRANG, Bertold D, CATANZARO, Jennifer L, THOMAS, James B, NAVARRO, Hernan A, GILMOUR, Brian P, DESCHAMPS, Jeffrey, CARROLL, F. Ivy
Published in Bioorganic & medicinal chemistry (15.01.2008)

Get full text

Journal Article

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

by HUANG KENNETH H, ATKINSON ROBERT N, OMMEN ANDY J, VEAL JAMES M, SMITH EMILIE D
Year of Publication 14.02.2014

Get full text

Patent

A new synthesis of the ORL-1 antagonist 1-[(3 R,4 R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2 H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay

A new synthesis of the ORL-1 antagonist 1-[(3 R,4 R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2 H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay

by Smith, Emilie D., Ariane Vinson, N., Zhong, Desong, Berrang, Bertold D., Catanzaro, Jennifer L., Thomas, James B., Navarro, Hernán A., Gilmour, Brian P., Deschamps, Jeffrey, Carroll, F. Ivy
Published in Bioorganic & medicinal chemistry (2008)

Get full text

Journal Article

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

by HUANG, KENNETH H, SMITH, EMILIE D, VEAL, JAMES M, OMMEN, ANDY J, ATKINSON, ROBERT N
Year of Publication 05.03.2019

Get full text

Patent

derivados de 2-arilimidazo [1,2-b] piridazina, 2-fenilimidazo [1,2-a] piridina, e 2-fenilimidazo [1,2-a] pirazina

derivados de 2-arilimidazo [1,2-b] piridazina, 2-fenilimidazo [1,2-a] piridina, e 2-fenilimidazo [1,2-a] pirazina

by ANDY J. OMMEN, JAMES M. VEAL, ROBERT N. ATKINSON, KENNETH H. HUANG, EMILIE D. SMITH
Year of Publication 10.07.2018

Get full text

Patent

2-arylimidazo[1,2-b]pyridazine, 2-phenylimidazo[1,2-a]pyridine, and 2-phenylimidazo[1,2-a]pyrazine derivatives

2-arylimidazo[1,2-b]pyridazine, 2-phenylimidazo[1,2-a]pyridine, and 2-phenylimidazo[1,2-a]pyrazine derivatives

by HUANG, KENNETH H, SMITH, EMILIE D, VEAL, JAMES M, OMMEN, ANDY J, ATKINSON, ROBERT N
Year of Publication 08.09.2016

Get full text

Patent

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

by HUANG, KENNETH H, VEAL, JAMES M, SMITH, EMILIE, D, OMMEN, ANDY J, ATKINSON, ROBERT N
Year of Publication 16.12.2015

Get full text

Patent

2-arylimidazo[1,2-B]pyridazine, 2-phenylimidazo[1,2-A]pyridine, and 2-phenylimidazo[1,2-A]pyrazine derivatives

2-arylimidazo[1,2-B]pyridazine, 2-phenylimidazo[1,2-A]pyridine, and 2-phenylimidazo[1,2-A]pyrazine derivatives

by HUANG KENNETH H, ATKINSON ROBERT N, OMMEN ANDY J, VEAL JAMES M, SMITH EMILIE D
Year of Publication 28.10.2014

Get full text

Patent

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

by HUANG, KENNETH H, VEAL, JAMES M, SMITH, EMILIE, D, OMMEN, ANDY J, ATKINSON, ROBERT N
Year of Publication 11.09.2013

Get full text

Patent

2-arylimidazo[1,2-b]pyridazine, 2-phenylimidazo[1,2-a]pyridine, and 2-phenylimidazo[1,2-a]pyrazine derivatives

2-arylimidazo[1,2-b]pyridazine, 2-phenylimidazo[1,2-a]pyridine, and 2-phenylimidazo[1,2-a]pyrazine derivatives

by HUANG, KENNETH H, SMITH, EMILIE D, VEAL, JAMES M, OMMEN, ANDY J, ATKINSON, ROBERT N
Year of Publication 20.06.2013

Get full text

Patent

Regioselective C-2 and C-6 Substitution of (S)-Nicotine and Nicotine Derivatives

Regioselective C-2 and C-6 Substitution of (S)-Nicotine and Nicotine Derivatives

by Fevrier, Florence C., Smith, Emilie D., Comins, Daniel L.
Published in ChemInform (11.04.2006)

Get full text

Journal Article

SYNTHESIS OF NICOTINE DERIVATIVES FROM NICOTINE

SYNTHESIS OF NICOTINE DERIVATIVES FROM NICOTINE

by COMINS DANIEL L, SMITH EMILIE D
Year of Publication 25.01.2007

Get full text

Patent