Search Results - "SMITH, EMILIE, D" :: K.UTB vyhledávací portál | TBU Library Retrieval Portal

Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents

Discovery of Novel 2-Aminobenzamide Inhibitors of Heat Shock Protein 90 as Potent, Selective and Orally Active Antitumor Agents

by Huang, Kenneth H, Veal, James M, Fadden, R. Patrick, Rice, John W, Eaves, Jeron, Strachan, Jon-Paul, Barabasz, Amy F, Foley, Briana E, Barta, Thomas E, Ma, Wei, Silinski, Melanie A, Hu, Mei, Partridge, Jeffrey M, Scott, Anisa, DuBois, Laura G, Freed, Tiffany, Steed, Paul M, Ommen, Andy J, Smith, Emilie D, Hughes, Philip F, Woodward, Angela R, Hanson, Gunnar J, McCall, W. Stephen, Markworth, Christopher J, Hinkley, Lindsay, Jenks, Matthew, Geng, Lifeng, Lewis, Meredith, Otto, James, Pronk, Bert, Verleysen, Katleen, Hall, Steven E
Published in Journal of medicinal chemistry (23.07.2009)

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Journal Article

Synthesis of C-4 Substituted Nicotine Derivatives via an N-Acylpyridinium Salt of (S)-Nicotine

Synthesis of C-4 Substituted Nicotine Derivatives via an N-Acylpyridinium Salt of (S)-Nicotine

by Comins, Daniel L, King, Laura S, Smith, Emilie D, Février, Florence C
Published in Organic letters (27.10.2005)

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Journal Article

Regioselective C-2 and C-6 Substitution of (S)-Nicotine and Nicotine Derivatives

Regioselective C-2 and C-6 Substitution of (S)-Nicotine and Nicotine Derivatives

by Février, Florence C, Smith, Emilie D, Comins, Daniel L
Published in Organic letters (24.11.2005)

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Journal Article

Synthesis of Nicotine Derivatives via Reductive Disilylation of (S)-Nicotine

Synthesis of Nicotine Derivatives via Reductive Disilylation of (S)-Nicotine

by Smith, Emilie D, Février, Florence C, Comins, Daniel L
Published in Organic letters (19.01.2006)

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Journal Article

Design, synthesis and biological evaluation of renin inhibitors guided by simulated annealing of chemical potential simulations

Design, synthesis and biological evaluation of renin inhibitors guided by simulated annealing of chemical potential simulations

by Cloudsdale, Ian S., Dickson, John K., Barta, Thomas E., Grella, Brian S., Smith, Emilie D., Kulp, John L., Guarnieri, Frank, Kulp, John L.
Published in Bioorganic & medicinal chemistry (01.08.2017)

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Journal Article

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90

Discovery of novel aminoquinazolin-7-yl 6,7-dihydro-indol-4-ones as potent, selective inhibitors of heat shock protein 90

by Huang, Kenneth H., Barta, Thomas E., Rice, John W., Smith, Emilie D., Ommen, Andy J., Ma, Wei, Veal, James M., Fadden, R. Patrick, Barabasz, Amy F., Foley, Briana E., Hughes, Philip F., Hanson, Gunnar J., Markworth, Christopher J., Silinski, Melanie, Partridge, Jeffrey M., Steed, Paul M., Hall, Steven E.
Published in Bioorganic & medicinal chemistry letters (01.04.2012)

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Journal Article

A six-step synthesis of ( S)-5-ethenyl-3-(1-methyl-2-pyrrolidinyl)pyridine (SIB-1508Y) from ( S)-nicotine

A six-step synthesis of ( S)-5-ethenyl-3-(1-methyl-2-pyrrolidinyl)pyridine (SIB-1508Y) from ( S)-nicotine

by Comins, Daniel L., Smith, Emilie D.
Published in Tetrahedron letters (27.02.2006)

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Journal Article

Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90

Application of Chemoproteomics to Drug Discovery: Identification of a Clinical Candidate Targeting Hsp90

by Fadden, Patrick, Huang, Kenneth H., Veal, James M., Steed, Paul M., Barabasz, Amy F., Foley, Briana, Hu, Mei, Partridge, Jeffrey M., Rice, John, Scott, Anisa, Dubois, Laura G., Freed, Tiffany A., Silinski, Melanie A. Rehder, Barta, Thomas E., Hughes, Philip F., Ommen, Andy, Ma, Wei, Smith, Emilie D., Spangenberg, Angela Woodward, Eaves, Jeron, Hanson, Gunnar J., Hinkley, Lindsay, Jenks, Matthew, Lewis, Meredith, Otto, James, Pronk, Gijsbertus J., Verleysen, Katleen, Haystead, Timothy A., Hall, Steven E.
Published in Chemistry & biology (30.07.2010)

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A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay

A new synthesis of the ORL-1 antagonist 1-[(3R,4R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay

by SMITH, Emilie D, ARIANE VINSON, N, DESONG ZHONG, BERRANG, Bertold D, CATANZARO, Jennifer L, THOMAS, James B, NAVARRO, Hernan A, GILMOUR, Brian P, DESCHAMPS, Jeffrey, CARROLL, F. Ivy
Published in Bioorganic & medicinal chemistry (15.01.2008)

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Journal Article

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

by HUANG KENNETH H, ATKINSON ROBERT N, OMMEN ANDY J, VEAL JAMES M, SMITH EMILIE D
Year of Publication 14.02.2014

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Patent

A new synthesis of the ORL-1 antagonist 1-[(3 R,4 R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2 H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay

A new synthesis of the ORL-1 antagonist 1-[(3 R,4 R)-1-cyclooctylmethyl-3-hydroxymethyl-4-piperidinyl]-3-ethyl-1,3-dihydro-2 H-benzimidazol-2-one (J-113397) and activity in a calcium mobilization assay

by Smith, Emilie D., Ariane Vinson, N., Zhong, Desong, Berrang, Bertold D., Catanzaro, Jennifer L., Thomas, James B., Navarro, Hernán A., Gilmour, Brian P., Deschamps, Jeffrey, Carroll, F. Ivy
Published in Bioorganic & medicinal chemistry (2008)

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Journal Article

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

by HUANG, KENNETH H, SMITH, EMILIE D, VEAL, JAMES M, OMMEN, ANDY J, ATKINSON, ROBERT N
Year of Publication 05.03.2019

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Patent

derivados de 2-arilimidazo [1,2-b] piridazina, 2-fenilimidazo [1,2-a] piridina, e 2-fenilimidazo [1,2-a] pirazina

derivados de 2-arilimidazo [1,2-b] piridazina, 2-fenilimidazo [1,2-a] piridina, e 2-fenilimidazo [1,2-a] pirazina

by ANDY J. OMMEN, JAMES M. VEAL, ROBERT N. ATKINSON, KENNETH H. HUANG, EMILIE D. SMITH
Year of Publication 10.07.2018

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Patent

2-arylimidazo[1,2-b]pyridazine, 2-phenylimidazo[1,2-a]pyridine, and 2-phenylimidazo[1,2-a]pyrazine derivatives

2-arylimidazo[1,2-b]pyridazine, 2-phenylimidazo[1,2-a]pyridine, and 2-phenylimidazo[1,2-a]pyrazine derivatives

by HUANG, KENNETH H, SMITH, EMILIE D, VEAL, JAMES M, OMMEN, ANDY J, ATKINSON, ROBERT N
Year of Publication 08.09.2016

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Patent

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

by HUANG, KENNETH H, VEAL, JAMES M, SMITH, EMILIE, D, OMMEN, ANDY J, ATKINSON, ROBERT N
Year of Publication 16.12.2015

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Patent

2-arylimidazo[1,2-B]pyridazine, 2-phenylimidazo[1,2-A]pyridine, and 2-phenylimidazo[1,2-A]pyrazine derivatives

2-arylimidazo[1,2-B]pyridazine, 2-phenylimidazo[1,2-A]pyridine, and 2-phenylimidazo[1,2-A]pyrazine derivatives

by HUANG KENNETH H, ATKINSON ROBERT N, OMMEN ANDY J, VEAL JAMES M, SMITH EMILIE D
Year of Publication 28.10.2014

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Patent

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

2-ARYLIMIDAZO[1,2-B]PYRIDAZINE, 2-PHENYLIMIDAZO[1,2-A]PYRIDINE, AND 2-PHENYLIMIDAZO[1,2-A]PYRAZINE DERIVATIVES

by HUANG, KENNETH H, VEAL, JAMES M, SMITH, EMILIE, D, OMMEN, ANDY J, ATKINSON, ROBERT N
Year of Publication 11.09.2013

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Patent

2-arylimidazo[1,2-b]pyridazine, 2-phenylimidazo[1,2-a]pyridine, and 2-phenylimidazo[1,2-a]pyrazine derivatives

2-arylimidazo[1,2-b]pyridazine, 2-phenylimidazo[1,2-a]pyridine, and 2-phenylimidazo[1,2-a]pyrazine derivatives

by HUANG, KENNETH H, SMITH, EMILIE D, VEAL, JAMES M, OMMEN, ANDY J, ATKINSON, ROBERT N
Year of Publication 20.06.2013

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Patent

Regioselective C-2 and C-6 Substitution of (S)-Nicotine and Nicotine Derivatives

Regioselective C-2 and C-6 Substitution of (S)-Nicotine and Nicotine Derivatives

by Fevrier, Florence C., Smith, Emilie D., Comins, Daniel L.
Published in ChemInform (11.04.2006)

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Journal Article

SYNTHESIS OF NICOTINE DERIVATIVES FROM NICOTINE

SYNTHESIS OF NICOTINE DERIVATIVES FROM NICOTINE

by COMINS DANIEL L, SMITH EMILIE D
Year of Publication 25.01.2007

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Patent