Local delivery of CpG-B and GM-CSF induces concerted activation of effector and regulatory T cells in the human melanoma sentinel lymph node
van den Hout, Mari F. C. M., Sluijter, Berbel J. R., Santegoets, Saskia J. A. M., van Leeuwen, Paul A. M., van den Tol, M. Petrousjka, van den Eertwegh, Alfons J. M., Scheper, Rik J., de Gruijl, Tanja D.
Published in Cancer Immunology, Immunotherapy (01.04.2016)
Published in Cancer Immunology, Immunotherapy (01.04.2016)
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Intradermal CpG-B Activates Both Plasmacytoid and Myeloid Dendritic Cells in the Sentinel Lymph Node of Melanoma Patients
MOLENKAMP, Barbara G, VAN LEEUWEN, Paul A. M, MEIJER, Sybren, SLUIJTER, Berbel J. R, WIJNANDS, Pepijn G. J. T. B, BAARS, Arnold, VAN DEN EERTWEGH, Alfons J. M, SCHEPER, Rik J, DE GRUIJL, Tanja D
Published in Clinical cancer research (15.05.2007)
Published in Clinical cancer research (15.05.2007)
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Local Adjuvant Treatment with Low-Dose CpG-B Offers Durable Protection against Disease Recurrence in Clinical Stage I-II Melanoma: Data from Two Randomized Phase II Trials
Koster, Bas D, van den Hout, Mari F C M, Sluijter, Berbel J R, Molenkamp, Barbara G, Vuylsteke, Ronald J C L M, Baars, Arnold, van Leeuwen, Paul A M, Scheper, Rik J, Petrousjka van den Tol, M, van den Eertwegh, Alfons J M, de Gruijl, Tanja D
Published in Clinical cancer research (01.10.2017)
Published in Clinical cancer research (01.10.2017)
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Characterization of four conventional dendritic cell subsets in human skin-draining lymph nodes in relation to T-cell activation
van de Ven, Rieneke, van den Hout, Mari F.C.M., Lindenberg, Jelle J., Sluijter, Berbel J.R., van Leeuwen, Paul A.M., Lougheed, Sinéad M., Meijer, Sybren, van den Tol, M. Petrousjka, Scheper, Rik J., de Gruijl, Tanja D.
Published in Blood (01.09.2011)
Published in Blood (01.09.2011)
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Favorable outcome in clinically stage II melanoma patients is associated with the presence of activated tumor infiltrating T‐lymphocytes and preserved MHC class I antigen expression
van Houdt, Inge S., Sluijter, Berbel J.R., Moesbergen, Laura M., Vos, Wim M., de Gruijl, Tanja D., Molenkamp, Barbara G., van den Eertwegh, Alfons J.M., Hooijberg, Erik, van Leeuwen, Paul A.M., Meijer, Chris J.L.M., Oudejans, Joost J.
Published in International journal of cancer (01.08.2008)
Published in International journal of cancer (01.08.2008)
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In the mix: the potential benefits of adding GM-CSF to CpG-B in the local treatment of patients with early-stage melanoma
Koster, Bas D., de Jong, Tamarah D., van den Hout, Mari F. C. M., Sluijter, Berbel J. R., Vuylsteke, Ronald J. C. L. M., Molenkamp, Barbara G., Vosslamber, Saskia, van den Tol, M. Petrousjka, van den Eertwegh, Alfons J. M., de Gruijl, Tanja D.
Published in Oncoimmunology (01.01.2020)
Published in Oncoimmunology (01.01.2020)
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T cell infiltration on local CpG-B delivery in early-stage melanoma is predominantly related to CLEC9A+CD141+ cDC1 and CD14+ antigen-presenting cell recruitment
Koster, Bas D, López González, Marta, van den Hout, Mari FCM, Turksma, Annelies W, Sluijter, Berbel JR, Molenkamp, Barbara G, van Leeuwen, Paul AM, Vosslamber, Saskia, Scheper, Rik J, van den Eertwegh, Alfons JM, van den Tol, M Petrousjka, Jordanova, Ekaterina J, de Gruijl, Tanja D
Published in Journal for immunotherapy of cancer (01.03.2021)
Published in Journal for immunotherapy of cancer (01.03.2021)
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Melanoma Sequentially Suppresses Different DC Subsets in the Sentinel Lymph Node, Affecting Disease Spread and Recurrence
van den Hout, Mari F C M, Koster, Bas D, Sluijter, Berbel J R, Molenkamp, Barbara G, van de Ven, Rieneke, van den Eertwegh, Alfons J M, Scheper, Rik J, van Leeuwen, Paul A M, van den Tol, M Petrousjka, de Gruijl, Tanja D
Published in Cancer immunology research (01.11.2017)
Published in Cancer immunology research (01.11.2017)
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Local Administration of PF-3512676 CpG-B Instigates Tumor-Specific CD8+ T-Cell Reactivity in Melanoma Patients
Molenkamp, Barbara G, Sluijter, Berbel J R, van Leeuwen, Paul A M, Santegoets, Saskia J A M, Meijer, Sybren, Wijnands, Pepijn G J T B, Haanen, John B A G, van den Eertwegh, Alfons J M, Scheper, Rik J, de Gruijl, Tanja D
Published in Clinical cancer research (15.07.2008)
Published in Clinical cancer research (15.07.2008)
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Arming the Melanoma Sentinel Lymph Node through Local Administration of CpG-B and GM-CSF: Recruitment and Activation of BDCA3/CD141(+) Dendritic Cells and Enhanced Cross-Presentation
Sluijter, Berbel J R, van den Hout, Mari F C M, Koster, Bas D, van Leeuwen, Paul A M, Schneiders, Famke L, van de Ven, Rieneke, Molenkamp, Barbara G, Vosslamber, Saskia, Verweij, Cornelis L, van den Tol, M Petrousjka, van den Eertwegh, Alfons J M, Scheper, Rik J, de Gruijl, Tanja D
Published in Cancer immunology research (01.05.2015)
Published in Cancer immunology research (01.05.2015)
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Immunomodulation of the melanoma sentinel lymph node: A novel adjuvant therapeutic option
Molenkamp, Barbara G., van Leeuwen, Paul A.M., van den Eertwegh, Alfons J.M., Sluijter, Berbel J.R., Scheper, Rik J., Meijer, Sybren, de Gruijl, Tanja D.
Published in Immunobiology (1979) (01.01.2006)
Published in Immunobiology (1979) (01.01.2006)
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Response: Breslow thickness and excision interval affect the activation state of Langerhans cells in melanoma sentinel lymph nodes
van den Hout, Mari F.C.M., Koster, Bas D., Sluijter, Berbel J.R., van Leeuwen, Paul A.M., Meijer, Sybren, van den Tol, Monique Petrousjka, van den Eertwegh, Alfons J.M., Scheper, Rik J., van de Ven, Rieneke, de Gruijl, Tanja D.
Published in Blood (17.05.2012)
Published in Blood (17.05.2012)
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Adjuvant treatment of early-stage melanoma by local i.d. administration of low-dose CpG-B and GM-CSF increases recurrence-free survival: long-term follow-up of three randomized clinical trials
de Gruijl, Tanja D, Koster, Bas D, van den Hout, Mari FCM, Sluijter, Berbel JR, Molenkamp, Barbara G, Vuylsteke, Ronald JCLM, van Leeuwen, Paul AM, Scheper, Rik J, van den Tol, Petrousjka, van den Eertwegh, Alfons
Published in Journal for immunotherapy of cancer (04.11.2015)
Published in Journal for immunotherapy of cancer (04.11.2015)
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