A Novel YAP1 Inhibitor Targets CSC-Enriched Radiation-Resistant Cells and Exerts Strong Antitumor Activity in Esophageal Adenocarcinoma
Song, Shumei, Xie, Min, Scott, Ailing W, Jin, Jiankang, Ma, Lang, Dong, Xiaochuan, Skinner, Heath D, Johnson, Randy L, Ding, Sheng, Ajani, Jaffer A
Published in Molecular cancer therapeutics (01.02.2018)
Published in Molecular cancer therapeutics (01.02.2018)
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Gain-of-Function Mutant p53 Promotes Cell Growth and Cancer Cell Metabolism via Inhibition of AMPK Activation
Zhou, Ge, Wang, Jiping, Zhao, Mei, Xie, Tong-Xin, Tanaka, Noriaki, Sano, Daisuke, Patel, Ameeta A., Ward, Alexandra M., Sandulache, Vlad C., Jasser, Samar A., Skinner, Heath D., Fitzgerald, Alison Lea, Osman, Abdullah A., Wei, Yongkun, Xia, Xuefeng, Songyang, Zhou, Mills, Gordon B., Hung, Mien-Chie, Caulin, Carlos, Liang, Jiyong, Myers, Jeffrey N.
Published in Molecular cell (19.06.2014)
Published in Molecular cell (19.06.2014)
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Integrative Analysis Identifies a Novel AXL-PI3 Kinase-PD-L1 Signaling Axis Associated with Radiation Resistance in Head and Neck Cancer
Skinner, Heath D, Giri, Uma, Yang, Liang P, Kumar, Manish, Liu, Ying, Story, Michael D, Pickering, Curtis R, Byers, Lauren A, Williams, Michelle D, Wang, Jing, Shen, Li, Yoo, Suk Y, Fan, You Hong, Molkentine, David P, Beadle, Beth M, Meyn, Raymond E, Myers, Jeffrey N, Heymach, John V
Published in Clinical cancer research (01.06.2017)
Published in Clinical cancer research (01.06.2017)
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TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence
SKINNER, Heath D, SANDULACHE, Vlad C, OW, Thomas J, MEYN, Raymond E, YORDY, John S, BEADLE, Beth M, FITZGERALD, Alison L, GIRI, Uma, KIAN ANG, K, MYERS, Jeffrey N
Published in Clinical cancer research (01.01.2012)
Published in Clinical cancer research (01.01.2012)
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Salvage pembrolizumab added to kinase inhibitor therapy for the treatment of anaplastic thyroid carcinoma
Iyer, Priyanka C, Dadu, Ramona, Gule-Monroe, Maria, Busaidy, Naifa L, Ferrarotto, Renata, Habra, Mouhammed Amir, Zafereo, Mark, Williams, Michelle D, Gunn, G Brandon, Grosu, Horiana, Skinner, Heath D, Sturgis, Erich M, Gross, Neil, Cabanillas, Maria E
Published in Journal for immunotherapy of cancer (11.07.2018)
Published in Journal for immunotherapy of cancer (11.07.2018)
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Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function
Kumar, Manish, Molkentine, David, Molkentine, Jessica, Bridges, Kathleen, Xie, Tongxin, Yang, Liangpeng, Hefner, Andrew, Gao, Meng, Bahri, Reshub, Dhawan, Annika, Frederick, Mitchell J., Seth, Sahil, Abdelhakiem, Mohamed, Beadle, Beth M., Johnson, Faye, Wang, Jing, Shen, Li, Heffernan, Timothy, Sheth, Aakash, Ferris, Robert L., Myers, Jeffrey N., Pickering, Curtis R., Skinner, Heath D.
Published in Nature communications (03.11.2021)
Published in Nature communications (03.11.2021)
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p16 Represses DNA Damage Repair via a Novel Ubiquitin-Dependent Signaling Cascade
Molkentine, David P, Molkentine, Jessica M, Bridges, Kathleen A, Valdecanas, David R, Dhawan, Annika, Bahri, Reshub, Hefner, Andrew J, Kumar, Manish, Yang, Liangpeng, Abdelhakiem, Mohamed, Pifer, Phillip M, Sandulache, Vlad, Sheth, Aakash, Beadle, Beth M, Thames, Howard D, Mason, Kathryn A, Pickering, Curtis R, Meyn, Raymond E, Skinner, Heath D
Published in Cancer research (Chicago, Ill.) (01.03.2022)
Published in Cancer research (Chicago, Ill.) (01.03.2022)
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Clinical Outcomes and Patterns of Disease Recurrence After Intensity Modulated Proton Therapy for Oropharyngeal Squamous Carcinoma
Gunn, G. Brandon, MD, Blanchard, Pierre, MD, PhD, Garden, Adam S., MD, Zhu, X. Ronald, PhD, Fuller, C. David, MD, PhD, Mohamed, Abdallah S., MD, PhD, Morrison, William H., MD, Phan, Jack, MD, PhD, Beadle, Beth M., MD, PhD, Skinner, Heath D., MD, PhD, Sturgis, Erich M., MD, Kies, Merrill S., MD, Hutcheson, Kate A., MD, Rosenthal, David I., MD, Mohan, Radhe, PhD, Gillin, Michael T., PhD, Frank, Steven J., MD
Published in International journal of radiation oncology, biology, physics (01.05.2016)
Published in International journal of radiation oncology, biology, physics (01.05.2016)
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BAP1 Is a Novel Target in HPV-Negative Head and Neck Cancer
Liu, Xiyou, Kumar, Manish, Yang, Liangpeng, Molkentine, David P, Valdecanas, David, Yu, Shiying, Meyn, Raymond E, Heymach, John V, Skinner, Heath D
Published in Clinical cancer research (01.02.2018)
Published in Clinical cancer research (01.02.2018)
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Metformin generates profound alterations in systemic and tumor immunity with associated antitumor effects
Veeramachaneni, Ratna, Yu, Wangjie, Newton, Jared M, Kemnade, Jan O, Skinner, Heath D, Sikora, Andrew G, Sandulache, Vlad C
Published in Journal for immunotherapy of cancer (01.07.2021)
Published in Journal for immunotherapy of cancer (01.07.2021)
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Evolutionary Action Score of TP53 Coding Variants Is Predictive of Platinum Response in Head and Neck Cancer Patients
Osman, Abdullah A, Neskey, David M, Katsonis, Panagiotis, Patel, Ameeta A, Ward, Alexandra M, Hsu, Teng-Kuei, Hicks, Stephanie C, McDonald, Thomas O, Ow, Thomas J, Alves, Marcus Ortega, Pickering, Curtis R, Skinner, Heath D, Zhao, Mei, Sturgis, Eric M, Kies, Merrill S, El-Naggar, Adel, Perrone, Federica, Licitra, Lisa, Bossi, Paolo, Kimmel, Marek, Frederick, Mitchell J, Lichtarge, Olivier, Myers, Jeffrey N
Published in Cancer research (Chicago, Ill.) (01.04.2015)
Published in Cancer research (Chicago, Ill.) (01.04.2015)
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Locoregional Failure Rate After Preoperative Chemoradiation of Esophageal Adenocarcinoma and the Outcomes of Salvage Strategies
SUDO, Kazuki, TAKETA, Takashi, SKINNER, Heath D, MARU, Dipen M, RICE, David C, SWISHER, Stephen G, HOFSTETTER, Wayne L, AJANI, Jaffer A, CORREA, Arlene M, CAMPAGNA, Maria-Claudia, WADHWA, Roopma, BLUM, Mariela A, KOMAKI, Ritsuko, LEE, Jeffrey H, BHUTANI, Manoop S, WESTON, Brian
Published in Journal of clinical oncology (01.12.2013)
Published in Journal of clinical oncology (01.12.2013)
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18-fluorodeoxy-glucose positron emission computed tomography as predictive of response after chemoradiation in oesophageal cancer patients
Elimova, Elena, Wang, Xuemei, Etchebehere, Elba, Shiozaki, Hironori, Shimodaira, Yusuke, Wadhwa, Roopma, Planjery, Venkatram, Charalampakis, Nikolaos, Blum, Mariela A, Hofstetter, Wayne, Lee, Jeff H, Weston, Brian R, Bhutani, Manoop S, Rogers, Jane E, Maru, Dipen, Skinner, Heath D, Macapinlac, Homer A, Ajani, Jaffer A
Published in European journal of cancer (1990) (01.11.2015)
Published in European journal of cancer (1990) (01.11.2015)
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Wee-1 Kinase Inhibition Sensitizes High-Risk HPV+ HNSCC to Apoptosis Accompanied by Downregulation of MCl-1 and XIAP Antiapoptotic Proteins
Tanaka, Noriaki, Patel, Ameeta A, Wang, Jiping, Frederick, Mitchell J, Kalu, Nene N, Zhao, Mei, Fitzgerald, Alison L, Xie, Tong-xin, Silver, Natalie L, Caulin, Carlos, Zhou, Ge, Skinner, Heath D, Johnson, Faye M, Myers, Jeffrey N, Osman, Abdullah A
Published in Clinical cancer research (01.11.2015)
Published in Clinical cancer research (01.11.2015)
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Nuclear expression of Gli-1 is predictive of pathologic complete response to chemoradiation in trimodality treated oesophageal cancer patients
Wadhwa, Roopma, Wang, Xuemei, Baladandayuthapani, Veerabhadran, Liu, Bin, Shiozaki, Hironori, Shimodaira, Yusuke, Lin, Quan, Elimova, Elena, Hofstetter, Wayne L, Swisher, Stephen G, Rice, David C, Maru, Dipen M, Kalhor, Neda, Bhutani, Manoop S, Weston, Brian, Lee, Jeffrey H, Skinner, Heath D, Scott, Ailing W, Kaya, Dilsa Mizrak, Harada, Kazuto, Berry, Donald, Song, Shumei, Ajani, Jaffer A
Published in British journal of cancer (22.08.2017)
Published in British journal of cancer (22.08.2017)
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Charged-Particle Therapy for Hepatocellular Carcinoma
Skinner, Heath D., MD, PhD, Hong, Theodore S., MD, Krishnan, Sunil, MD
Published in Seminars in radiation oncology (01.10.2011)
Published in Seminars in radiation oncology (01.10.2011)
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Caspase-8 loss radiosensitizes head and neck squamous cell carcinoma to SMAC mimetic-induced necroptosis
Uzunparmak, Burak, Gao, Meng, Lindemann, Antje, Erikson, Kelly, Wang, Li, Lin, Eric, Frank, Steven J, Gleber-Netto, Frederico O, Zhao, Mei, Skinner, Heath D, Newton, Jared, Sikora, Andrew G, Myers, Jeffrey N, Pickering, Curtis R
Published in JCI insight (03.12.2020)
Published in JCI insight (03.12.2020)
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Glycolytic inhibition alters anaplastic thyroid carcinoma tumor metabolism and improves response to conventional chemotherapy and radiation
Sandulache, Vlad C, Skinner, Heath D, Wang, Yuan, Chen, Yunyun, Dodge, Cristina T, Ow, Thomas J, Bankson, James A, Myers, Jeffrey N, Lai, Stephen Y
Published in Molecular cancer therapeutics (01.06.2012)
Published in Molecular cancer therapeutics (01.06.2012)
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