Receptor activity-modifying protein modulation of parathyroid hormone-1 receptor function and signaling
Avgoustou, Paris, Jailani, Ameera B A, Desai, Aditya J, Roberts, David J, Lilley, Ewan R, Stothard, Grant W, Skerry, Timothy M, Richards, Gareth O
Published in Frontiers in pharmacology (23.09.2024)
Published in Frontiers in pharmacology (23.09.2024)
Get full text
Journal Article
Zinc‐Induced Effects on Osteoclastogenesis Involves Activation of Hyperpolarization‐Activated Cyclic Nucleotide Modulated Channels via Changes in Membrane Potential
Notomi, Takuya, Kuno, Miyuki, Hiyama, Akiko, Ohura, Kiyoshi, Noda, Masaki, Skerry, Timothy M
Published in Journal of bone and mineral research (01.09.2015)
Published in Journal of bone and mineral research (01.09.2015)
Get full text
Journal Article
Mechanical loading: biphasic osteocyte survival and targeting of osteoclasts for bone destruction in rat cortical bone
Noble, Brendon S, Peet, Nicky, Stevens, Hazel Y, Brabbs, Alex, Mosley, John R, Reilly, Gwendolen C, Reeve, Jonathan, Skerry, Timothy M, Lanyon, Lance E
Published in American Journal of Physiology: Cell Physiology (01.04.2003)
Published in American Journal of Physiology: Cell Physiology (01.04.2003)
Get full text
Journal Article
NMDA receptor–mediated regulation of human megakaryocytopoiesis
Hitchcock, Ian S., Skerry, Timothy M., Howard, Martin R., Genever, Paul G.
Published in Blood (15.08.2003)
Published in Blood (15.08.2003)
Get full text
Journal Article
Modulation of Glucagon Receptor Pharmacology by Receptor Activity-modifying Protein-2 (RAMP2)
Weston, Cathryn, Lu, Jing, Li, Naichang, Barkan, Kerry, Richards, Gareth O., Roberts, David J., Skerry, Timothy M., Poyner, David, Pardamwar, Meenakshi, Reynolds, Christopher A., Dowell, Simon J., Willars, Gary B., Ladds, Graham
Published in The Journal of biological chemistry (18.09.2015)
Published in The Journal of biological chemistry (18.09.2015)
Get full text
Journal Article
Analysis of mechanotransduction dynamics during combined mechanical stimulation and modulation of the extracellular-regulated kinase cascade uncovers hidden information within the signalling noise
Ascolani, Gianluca, Skerry, Timothy M, Lacroix, Damien, Dall'Ara, Enrico, Shuaib, Aban
Published in Interface focus (06.02.2021)
Published in Interface focus (06.02.2021)
Get full text
Journal Article
Discovery of a First-In-Class Small Molecule Antagonist against the Adrenomedullin‑2 Receptor: Structure–Activity Relationships and Optimization
Zirimwabagabo, Jean-Olivier, Jailani, Ameera B. A, Avgoustou, Paris, Tozer, Matthew J, Gibson, Karl R, Glossop, Paul A, Mills, James E. J, Porter, Roderick A, Blaney, Paul, Wang, Ning, Skerry, Timothy M, Richards, Gareth O, Harrity, Joseph P. A
Published in Journal of medicinal chemistry (25.03.2021)
Published in Journal of medicinal chemistry (25.03.2021)
Get full text
Journal Article
Targeting the adrenomedullin-2 receptor for the discovery and development of novel anti-cancer agents
Jailani, Ameera B. A., Bigos, Kamilla J. A., Avgoustou, Paris, Egan, Joseph L., Hathway, Robert A., Skerry, Timothy M., Richards, Gareth O.
Published in Expert opinion on drug discovery (03.08.2022)
Published in Expert opinion on drug discovery (03.08.2022)
Get full text
Journal Article
The P2Y13 receptor regulates extracellular ATP metabolism and the osteogenic response to mechanical loading
Wang, Ning, Rumney, Robin MH, Yang, Lang, Robaye, Bernard, Boeynaems, Jean‐Marie, Skerry, Timothy M, Gartland, Alison
Published in Journal of bone and mineral research (01.06.2013)
Published in Journal of bone and mineral research (01.06.2013)
Get full text
Journal Article
Inhibition of glutamate regulated calcium entry into leukemic megakaryoblasts reduces cell proliferation and supports differentiation
Kamal, Tania, Green, Taryn N., Morel-Kopp, Marie-Christine, Ward, Christopher M., McGregor, Ailsa L., McGlashan, Susan R., Bohlander, Stefan K., Browett, Peter J., Teague, Lochie, During, Matthew J., Skerry, Timothy M., Josefsson, Emma C., Kalev-Zylinska, Maggie L.
Published in Cellular signalling (01.09.2015)
Published in Cellular signalling (01.09.2015)
Get full text
Journal Article
Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma
Croucher, Peter I., Shipman, Claire M., Lippitt, Jennifer, Perry, Mark, Asosingh, Kewal, Hijzen, Anja, Brabbs, Alex C., van Beek, Edwin J.R., Holen, Ingunn, Skerry, Timothy M., Dunstan, Colin R., Russell, Graham R., Van Camp, Ben, Vanderkerken, Karin
Published in Blood (15.12.2001)
Published in Blood (15.12.2001)
Get full text
Journal Article
Absence of mechanical loading in utero influences bone mass and architecture but not innervation in Myod‐Myf5‐deficient mice
Gomez, Cédric, David, Valentin, Peet, Nicola M., Vico, Laurence, Chenu, Chantal, Malaval, Luc, Skerry, Timothy M.
Published in Journal of anatomy (01.03.2007)
Published in Journal of anatomy (01.03.2007)
Get full text
Journal Article
Reduced Bone Turnover in Mice Lacking the P2Y13 Receptor of ADP
Wang, Ning, Robaye, Bernard, Agrawal, Ankita, Skerry, Timothy M, Boeynaems, Jean-Marie, Gartland, Alison
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2012)
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2012)
Get full text
Journal Article
Discovery of a First-in-Class Potent Small Molecule Antagonist against the Adrenomedullin‑2 Receptor
Avgoustou, Paris, Jailani, Ameera B. A, Zirimwabagabo, Jean-Olivier, Tozer, Matthew J, Gibson, Karl R, Glossop, Paul A, Mills, James E. J, Porter, Roderick A, Blaney, Paul, Bungay, Peter J, Wang, Ning, Shaw, Alice P, Bigos, Kamilla J. A, Holmes, Joseph L, Warrington, Jessica I, Skerry, Timothy M, Harrity, Joseph P. A, Richards, Gareth O
Published in ACS pharmacology & translational science (14.08.2020)
Published in ACS pharmacology & translational science (14.08.2020)
Get full text
Journal Article