Structure of full-length porcine synovial collagenase reveals a C-terminal domain containing a calcium-linked, four-bladed β-propeller
Li, J, Brick, P, O'Hare, MC, Skarzynski, T, Lloyd, LF, Curry, VA, Clark, IM, Bigg, HF, Hazleman, BL, Cawston, TE, Blow, DM
Published in Structure (London) (15.06.1995)
Published in Structure (London) (15.06.1995)
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Probing the coenzyme specificity of glyceraldehyde-3-phosphate dehydrogenases by site-directed mutagenesis
Corbier, C, Clermont, S, Billard, P, Skarzynski, T, Branlant, C, Wonacott, A, Branlant, G
Published in Biochemistry (Easton) (31.07.1990)
Published in Biochemistry (Easton) (31.07.1990)
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Bonding of molecular oxygen to T state human haemoglobin
Brzozowski, A, Derewenda, Z, Dodson, E, Dodson, G, Grabowski, M, Liddington, R, Skarzyński, T, Vallely, D
Published in Nature (London) (01.01.1984)
Published in Nature (London) (01.01.1984)
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Structure of UDP- N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP- N-acetylglucosamine and the drug fosfomycin
Skarzynski, Tadeusz, Mistry, Anil, Wonacott, Alan, Hutchinson, Susan E, Kelly, Valerie A, Duncan, Kenneth
Published in Structure (London) (15.12.1996)
Published in Structure (London) (15.12.1996)
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Dihydropyrancarboxamides Related to Zanamivir: A New Series of Inhibitors of Influenza Virus Sialidases. 2. Crystallographic and Molecular Modeling Study of Complexes of 4-Amino-4H-pyran-6-carboxamides and Sialidase from Influenza Virus Types A and B
Taylor, Neil R, Cleasby, Anne, Singh, Onkar, Skarzynski, Tadeusz, Wonacott, Alan J, Smith, Paul W, Sollis, Steven L, Howes, Peter D, Cherry, Peter C, Bethell, Richard, Colman, Peter, Varghese, Jose
Published in Journal of medicinal chemistry (12.03.1998)
Published in Journal of medicinal chemistry (12.03.1998)
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Industrial perspective on X-ray data collection and analysis
Skarzynski, Tadeusz, Thorpe, James
Published in Acta crystallographica. Section D, Biological crystallography. (01.01.2006)
Published in Acta crystallographica. Section D, Biological crystallography. (01.01.2006)
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The high-resolution crystal structure of a 24-kDa gyrase B fragment from E. coli complexed with one of the most potent coumarin inhibitors, clorobiocin
Tsai, Francis T.F., Singh, Onkar M.P., Skarzynski, Tadeusz, Wonacott, Alan J., Weston, Simon, Tucker, Alec, Pauptit, Richard A., Breeze, Alexander L., Poyser, J. Philip, O'Brien, Ronan, Ladbury, John E., Wigley, Dale B.
Published in Proteins, structure, function, and bioinformatics (01.05.1997)
Published in Proteins, structure, function, and bioinformatics (01.05.1997)
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A new interface to the Cambridge Structural Database (CSD) in CrysAlisPro
White, F. J., Gál, Z., Griffin, A., Skarzynski, T., Meyer, M., Prochniak, G., Wood, P. A., Thomas, I. R.
Published in Acta crystallographica. Section A, Foundations of crystallography (22.08.2011)
Published in Acta crystallographica. Section A, Foundations of crystallography (22.08.2011)
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Crystal structure of the Ffh and EF-G binding sites in the conserved domain IV of Escherichia coli 4.5S RNA
Jovine, Luca, Hainzl, Tobias, Oubridge, Chris, Scott, William G, Li, Jade, Sixma, Titia K, Wonacott, Alan, Skarzynski, Tadeusz, Nagai, Kiyoshi
Published in Structure (London) (15.05.2000)
Published in Structure (London) (15.05.2000)
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Stereochemical Course of Enzymatic Enolpyruvyl Transfer and Catalytic Conformation of the Active Site Revealed by the Crystal Structure of the Fluorinated Analogue of the Reaction Tetrahedral Intermediate Bound to the Active Site of the C115A Mutant of MurA
Skarzynski, Tadeusz, Kim, Dennis H, Lees, Watson J, Walsh, Christopher T, Duncan, Kenneth
Published in Biochemistry (Easton) (24.02.1998)
Published in Biochemistry (Easton) (24.02.1998)
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Pyrrolidine-5,5-trans-lactams. 4. Incorporation of a P3/P4 Urea Leads to Potent Intracellular Inhibitors of Hepatitis C Virus NS3/4A Protease
Slater, Martin J, Amphlett, Elizabeth M, Andrews, David M, Bamborough, Paul, Carey, Seb J, Johnson, Martin R, Jones, Paul S, Mills, Gail, Parry, Nigel R, Stewart, Alan J, Skarzynski, Tadeusz
Published in Organic letters (27.11.2003)
Published in Organic letters (27.11.2003)
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The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase—GW311616A a development candidate
Macdonald, Simon J.F, Dowle, Michael D, Harrison, Lee A, Shah, Pritom, Johnson, Martin R, Inglis, Graham G.A, Clarke, Geoffrey D.E, Smith, Robin A, Humphreys, Davina, Molloy, Christopher R, Amour, Augustin, Dixon, Mary, Murkitt, Graham, Godward, Rosalind E, Padfield, Tony, Skarzynski, Tadeusz, Singh, Onkar M.P, Kumar, K.Abhhilash, Fleetwood, Gill, Hodgson, Simon T, Hardy, George W, Finch, Harry
Published in Bioorganic & medicinal chemistry letters (09.04.2001)
Published in Bioorganic & medicinal chemistry letters (09.04.2001)
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Pyrrolidine-5,5-trans-lactams. 2. The Use of X-ray Crystal Structure Data in the Optimization of P3 and P4 Substituents
Andrews, David M, Chaignot, Helene, Coomber, Barry A, Good, Andrew C, Hind, S. Lucy, Johnson, Martin R, Jones, Paul S, Mills, Gail, Robinson, J. Ed, Skarzynski, Tadeusz, Slater, Martin J, Somers, Donald O'N
Published in Organic letters (12.12.2002)
Published in Organic letters (12.12.2002)
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Crystallization and preliminary X-ray analysis of porcine synovial collagenase
Lloyd, L.F., Skarżyński, T., Wonacott, A.J., Cawston, T.E., Clark, I.M., Mannix, C.J., Harper, G.P.
Published in Journal of molecular biology (05.11.1989)
Published in Journal of molecular biology (05.11.1989)
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Intracellular inhibition of human neutrophil elastase by orally active pyrrolidine-trans-lactams
MACDONALD, Simon J. F, DOWLE, Michael D, MOLLOY, Christopher R, DIXON, Mary, MURKITT, Graham, GODWARD, Rosalind E, SKARZYNSKI, Tadeusz, SINGH, Onkar M. P, KUMAR, K. Abhhilash, HODGSON, Simon T, MCDONALD, Edward, HARDY, George W, HARRISON, Lee A, FINCH, Harry, SPOONER, Julie E, SHAH, Pritom, JOHNSON, Martin R, INGLIS, Graham G. A, CLARKE, Geoffrey D. E, BELTON, David J, SMITH, Robin A
Published in Bioorganic & medicinal chemistry letters (22.01.2001)
Published in Bioorganic & medicinal chemistry letters (22.01.2001)
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