Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action
Lötsch, Jörn, Skarke, Carsten, Wieting, Johannes, Oertel, Bruno Georg, Schmidt, Helmut, Brockmöller, Jürgen, Geisslinger, Gerd
Published in Clinical pharmacology and therapeutics (01.01.2006)
Published in Clinical pharmacology and therapeutics (01.01.2006)
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Journal Article
Effects of selective COX‐2 inhibition on prostanoids and platelet physiology in young healthy volunteers
GRAFF, J., SKARKE, C., KLINKHARDT, U., WATZER, B., HARDER, S., SEYBERTH, H., GEISSLINGER, G., NÜSING, R. M.
Published in Journal of thrombosis and haemostasis (01.12.2007)
Published in Journal of thrombosis and haemostasis (01.12.2007)
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Journal Article
Respiratory and miotic effects of morphine in healthy volunteers when P-glycoprotein is blocked by quinidine
Skarke, Carsten, Jarrar, Marwan, Erb, Katharina, Schmidt, Helmut, Geisslinger, Gerd, Lötsch, Jörn
Published in Clinical pharmacology and therapeutics (01.10.2003)
Published in Clinical pharmacology and therapeutics (01.10.2003)
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Journal Article
The transfer half-life of morphine-6-glucuronide from plasma to effect site assessed by Pupil size measurement in healthy volunteers
LÖTSCH, Jörn, SKARKE, Carsten, SCHMIDT, Helmut, GRÖSCH, Sabine, GEISSLINGER, Gerd
Published in Anesthesiology (Philadelphia) (01.12.2001)
Published in Anesthesiology (Philadelphia) (01.12.2001)
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Conference Proceeding
Journal Article
Drug interactions with patient-controlled analgesia
LÖTSCH, Jörn, SKARKE, Carsten, TEGEDER, Irmgard, GEISSLINGER, Gerd
Published in Clinical pharmacokinetics (2002)
Published in Clinical pharmacokinetics (2002)
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Journal Article
Pharmacokinetic modeling to predict morphine and morphine-6-glucuronide plasma concentrations in healthy young volunteers
Lötsch, Jörn, Skarke, Carsten, Schmidt, Helmut, Liefhold, Jürgen, Geisslinger, Gerd
Published in Clinical pharmacology and therapeutics (01.08.2002)
Published in Clinical pharmacology and therapeutics (01.08.2002)
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Journal Article
The influence of inhibition of probenecid sensitive transporters on the central nervous system (CNS) uptake and the antinociceptive activity of morphine-6-glucuronide in rats
Lötsch, Jörn, Schmidt, Rodolfo, Vetter, Gregor, Schmidt, Helmut, Skarke, Carsten, Niederberger, Ellen, Geisslinger, Gerd, Tegeder, Irmgard
Published in Neuroscience letters (30.08.2002)
Published in Neuroscience letters (30.08.2002)
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Journal Article
Effects of Cytokines on the Expression of Cell Adhesion Molecules by Cultured Human Omental Mesothelial Cells
Klein, Christoph L., Bittinger, Fernando, Skarke, Carsten C., Wagner, Mechthild, Köhler, Holger, Walgenbach, Siegfried, Kirkpatrick, James
Published in Pathobiology (Basel) (1995)
Published in Pathobiology (Basel) (1995)
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Journal Article
The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine
Lötsch, Jörn, Skarke, Carsten, Grösch, Sabine, Darimont, Jutta, Schmidt, Helmut, Geisslinger, Gerd
Published in Pharmacogenetics (London) (01.01.2002)
Published in Pharmacogenetics (London) (01.01.2002)
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Journal Article
Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers
Skarke, Carsten, Darimont, Jutta, Schmidt, Helmut, Geisslinger, Gerd, Lötsch, Jörn
Published in Clinical pharmacology and therapeutics (01.01.2003)
Published in Clinical pharmacology and therapeutics (01.01.2003)
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Journal Article
Does the A118G polymorphism at the μ-opioid receptor gene protect against morphine-6-glucuronide toxicity?
LÖTSCH, Jörn, ZIMMERMANN, Michael, DARIMONT, Jutta, MARX, Claudia, DUDZIAK, Rafael, SKARKE, Carsten, GEISSLINGER, Gerd
Published in Anesthesiology (Philadelphia) (01.10.2002)
Published in Anesthesiology (Philadelphia) (01.10.2002)
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Journal Article
Evidence for morphine-independent central nervous opioid effects after administration of codeine: contribution of other codeine metabolites
Lötsch, Jörn, Skarke, Carsten, Schmidt, Helmut, Rohrbacher, Maren, Hofmann, Ute, Schwab, Matthias, Geisslinger, Gerd
Published in Clinical pharmacology and therapeutics (01.01.2006)
Published in Clinical pharmacology and therapeutics (01.01.2006)
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Journal Article
Olfactory Function in Mild Cognitive Impairment and Alzheimer's Disease: An Investigation Using Psychophysical and Electrophysiological Techniques
Peters, Jürgen M., Hummel, Thomas, Kratzsch, Tilman, Lötsch, Jörn, Skarke, Carsten, Frölich, Lutz
Published in The American journal of psychiatry (01.11.2003)
Published in The American journal of psychiatry (01.11.2003)
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Journal Article