Adventitial endothelial implants reduce matrix metalloproteinase-2 expression and increase luminal diameter in porcine arteriovenous grafts
Nugent, Helen M., PhD, Tjin Tham Sjin, Robert, PhD, White, Desmond, BS, Milton, Luther G., LATG, Manson, Roberto J., MD, Lawson, Jeffrey H., MD, PhD, Edelman, Elazer R., MD, PhD
Published in Journal of vascular surgery (01.09.2007)
Published in Journal of vascular surgery (01.09.2007)
Get full text
Journal Article
A 27-amino-acid synthetic peptide corresponding to the NH2-terminal zinc-binding domain of endostatin is responsible for its antitumor activity
TJIN THAM SJIN, Robert M, SATCHI-FAINARO, Ronit, BIRSNER, Amy E, SADAGOPA RAMANUJAM, V. M, FOLKMAN, Judah, JAVAHERIAN, Kashi
Published in Cancer research (Chicago, Ill.) (01.05.2005)
Published in Cancer research (Chicago, Ill.) (01.05.2005)
Get full text
Journal Article
Linking Antibody Fc Domain to Endostatin Significantly Improves Endostatin Half-life and Efficacy
LEE, Tong-Young, SJIN, Robert M. Tjintham, MOVAHEDI, Shahla, AHMED, Bissan, PRAVDA, Elke A, LO, Kin-Ming, GILLIES, Stephen D, FOLKMAN, Judah, JAVAHERIAN, Kashi
Published in Clinical cancer research (01.03.2008)
Published in Clinical cancer research (01.03.2008)
Get full text
Journal Article
VRK1 Is a Synthetic-Lethal Target in VRK2-Deficient Glioblastoma
Shields, Julie A, Meier, Samuel R, Bandi, Madhavi, Mulkearns-Hubert, Erin E, Hajdari, Nicole, Ferdinez, Maria Dam, Engel, Justin L, Silver, Daniel J, Shen, Binzhang, Zhang, Wenhai, Hubert, Christopher G, Mitchell, Kelly, Shakya, Sajina, Zhao, Shan-Chuan, Bejnood, Alborz, Zhang, Minjie, Tjin Tham Sjin, Robert, Wilker, Erik, Lathia, Justin D, Andersen, Jannik N, Chen, Yingnan, Li, Fang, Weber, Barbara, Huang, Alan, Emmanuel, Natasha
Published in Cancer research (Chicago, Ill.) (02.11.2022)
Published in Cancer research (Chicago, Ill.) (02.11.2022)
Get full text
Journal Article
In vitro and in vivo characterization of irreversible mutant-selective EGFR inhibitors that are wild-type sparing
Tjin Tham Sjin, Robert, Lee, Kwangho, Walter, Annette O, Dubrovskiy, Aleksandr, Sheets, Michael, Martin, Thia St, Labenski, Matthew T, Zhu, Zhendong, Tester, Richland, Karp, Russell, Medikonda, Aravind, Chaturvedi, Prasoon, Ren, Yixuan, Haringsma, Henry, Etter, Jeff, Raponi, Mitch, Simmons, Andrew D, Harding, Thomas C, Niu, Deqiang, Nacht, Mariana, Westlin, William F, Petter, Russell C, Allen, Andrew, Singh, Juswinder
Published in Molecular cancer therapeutics (01.06.2014)
Published in Molecular cancer therapeutics (01.06.2014)
Get full text
Journal Article
Discovery of Selective, Covalent FGFR4 Inhibitors with Antitumor Activity in Models of Hepatocellular Carcinoma
Liu, Haibo, Niu, Deqiang, Tham Sjin, Robert Tjin, Dubrovskiy, Alex, Zhu, Zhendong, McDonald, Joseph J, Fahnoe, Kelly, Wang, Zhigang, Munson, Mark, Scholte, Andrew, Barrague, Matthieu, Fitzgerald, Maria, Liu, Jinyu, Kothe, Michael, Sun, Fangxian, Murtie, Joshua, Ge, Jie, Rocnik, Jennifer, Harvey, Darren, Ospina, Beatriz, Perron, Keli, Zheng, Gang, Shehu, Elvis, D’Agostino, Laura Akullian
Published in ACS medicinal chemistry letters (08.10.2020)
Published in ACS medicinal chemistry letters (08.10.2020)
Get full text
Journal Article
NF-κB drives acquired resistance to a novel mutant-selective EGFR inhibitor
Galvani, Elena, Sun, Jing, Leon, Leticia G, Sciarrillo, Rocco, Narayan, Ravi S, Sjin, Robert Tjin Tham, Lee, Kwangho, Ohashi, Kadoaki, Heideman, Daniëlle A M, Alfieri, Roberta R, Heynen, Guus J, Bernards, René, Smit, Egbert F, Pao, William, Peters, Godefridus J, Giovannetti, Elisa
Published in Oncotarget (15.12.2015)
Published in Oncotarget (15.12.2015)
Get full text
Journal Article
HETEROARYL COMPOUNDS AND USES THEREOF
MANIAR SACHIN, LIU HAIBO, MCDONALD JOSEPH JOHN, BARRAGUE MATTHIEU, GROSS ALEXANDRE, HARVEY DARREN, D'AGOSTINO LAURA AKULLIAN, MAZDIYASNI HORMOZ, ZHU ZHENDONG, NIU DEQIANG, PETTER RUSSELL C, SJIN ROBERT TJIN THAM, MUNSON MARK, SCHOLTE ANDREW, SINGH JUSWINDER
Year of Publication 02.03.2021
Get full text
Year of Publication 02.03.2021
Patent
Superiority of a novel EGFR targeted covalent inhibitor over its reversible counterpart in overcoming drug resistance
Singh, Juswinder, Evans, Erica, Hagel, Margit, Labinski, Matthew, Dubrovskiy, Alex, Nacht, Mariana, Petter, Russell C., Prasad, Aravind, Sheets, Michael, St Martin, Thia, Tjin Tham Sjin, Robert, Westlin, William, Zhu, Zhendong
Published in MedChemComm (01.07.2012)
Published in MedChemComm (01.07.2012)
Get full text
Journal Article
Interleukin-6 and Leukemia Inhibitory Factor Induction of JunB Is Regulated by Distinct Cell Type-specific Cis-acting Elements
Sjin, Robert M. Tjin Tham, Lord, Kenneth A., Abdollahi, Abbas, Hoffman, Barbara, Liebermann, Dan A.
Published in The Journal of biological chemistry (01.10.1999)
Published in The Journal of biological chemistry (01.10.1999)
Get full text
Journal Article
HETEROARYL COMPOUNDS AND USES THEREOF
MANIAR SACHIN, LIU HAIBO, MCDONALD JOSEPH JOHN, BARRAGUE MATTHIEU, GROSS ALEXANDRE, HARVEY DARREN, D'AGOSTINO LAURA AKULLIAN, MAZDIYASNI HORMOZ, ZHU ZHENDONG, NIU DEQIANG, PETTER RUSSELL C, SJIN ROBERT TJIN THAM, MUNSON MARK, SCHOLTE ANDREW, SINGH JUSWINDER
Year of Publication 24.11.2015
Get full text
Year of Publication 24.11.2015
Patent
Laminin Modulates Morphogenic Properties of the Collagen XVIII Endostatin Domain
Javaherian, Kashi, Park, Susan Y, Pickl, Winfried F, LaMontagne, Kenneth R, Sjin, Robert Tjin Tham, Gillies, Stephen, Lo, Kin-Ming
Published in The Journal of biological chemistry (22.11.2002)
Published in The Journal of biological chemistry (22.11.2002)
Get full text
Journal Article
Discovery of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC
Walter, Annette O, Sjin, Robert Tjin Tham, Haringsma, Henry J, Ohashi, Kadoaki, Sun, Jing, Lee, Kwangho, Dubrovskiy, Aleksandr, Labenski, Matthew, Zhu, Zhendong, Wang, Zhigang, Sheets, Michael, St Martin, Thia, Karp, Russell, van Kalken, Dan, Chaturvedi, Prasoon, Niu, Deqiang, Nacht, Mariana, Petter, Russell C, Westlin, William, Lin, Kevin, Jaw-Tsai, Sarah, Raponi, Mitch, Van Dyke, Terry, Etter, Jeff, Weaver, Zoe, Pao, William, Singh, Juswinder, Simmons, Andrew D, Harding, Thomas C, Allen, Andrew
Published in Cancer discovery (01.12.2013)
Published in Cancer discovery (01.12.2013)
Get full text
Journal Article
Abstract P146: Loss of HS2ST1 cooperates with MAPK inhibition to impair growth of mesenchymal KRAS mutant NSCLC
Ahronian, Leanne G., Fenoglio, Silvia, Das, Nikitha, Aird, Daniel, Guerin, David, Whittington, Douglas, Jahic, Haris, Brophy, Erin, McCarren, Patrick, McMillan, Brian, Tepper, James, Mentzer, Michaela, Li, Fang, Zhang, Hongxiang, Pan, Xuewen, Maxwell, John, Andersen, Jannik, Huang, Alan, Sjin, Robert Tjin Tham
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
Get full text
Journal Article
Abstract P182: VRK1 is a novel synthetic lethal target in VRK2-methylated glioblastoma
Shields, Julie, Meier, Samuel R., Engel, Justin, Bandi, Madhavi, Dam Ferdinez, Maria L., Zhang, Wenhai, Zhao, Shan-chuan, Zhang, Minjie, Choi, Ashley, Yu, Yi, Pan, Xuewen, McMillan, Brian, Williams, Brett, Sjin, Robert Tjin Tham, Whittington, Douglas, Wilker, Erik, Huang, Alan, Li, Fang, Emmanuel, Natasha
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
Get full text
Journal Article
Abstract P183: CRISPR screens identify sensitizers to trametinib in KRAS mutant cancer cell lines
Fenoglio, Silvia, Cristo, Aileen M., Tepper, James, Teng, Teng, Meier, Samuel R., Choi, Ashley, Zhang, Hongxiang, Zhao, Shan-chuan, Liu, Shangtao, Ahronian, Leanne G., Aird, Daniel, Das, Nikitha M., Yu, Yi, Sjin, Robert Tjin Tham, Andersen, Jannik N., Huang, Alan, Li, Fang, Pan, Xuewen
Published in Molecular cancer therapeutics (01.12.2021)
Published in Molecular cancer therapeutics (01.12.2021)
Get full text
Journal Article
CNSC-36. VRK1 IS A PARALOG SYNTHETIC LETHAL TARGET IN VRK2-METHYLATED GLIOBLASTOMA
Shields, Julie, Meier, Samuel, Bandi, Madhavi, Ferdinez, Maria Dam, Engel, Justin, Mulkearns-Hubert, Erin, Hajdari, Nicole, Shen, Binzhang, Hubert, Christopher, Mitchell, Kelly, Zhang, Wenhai, Zhao, Shan-chuan, Bejnood, Alborz, Zhang, Minjie, Sjin, Robert Tjin Tham, Wilker, Erik, Lathia, Justin, Andersen, Jannik, Chen, Yingnan, Li, Fang, Weber, Barbara, Huang, Alan, Emmanuel, Natasha
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Published in Neuro-oncology (Charlottesville, Va.) (14.11.2022)
Get full text
Journal Article
Abstract B120: Preclinical assessment of a mutant-selective covalent inhibitor of EGFR that overcomes T790M-mediated resistance in NSCLC
Simmons, Andrew D., Haringsma, Henry J., Walter, Annette O., Tjin Tham Sjin, Robert, Weaver, Zoe, Allen, Andrew, Harding, Thomas C.
Published in Molecular cancer therapeutics (01.11.2013)
Published in Molecular cancer therapeutics (01.11.2013)
Get full text
Journal Article