Dual base editor catalyzes both cytosine and adenine base conversions in human cells
Zhang, Xiaohui, Zhu, Biyun, Chen, Liang, Xie, Ling, Yu, Weishi, Wang, Ying, Li, Linxi, Yin, Shuming, Yang, Lei, Hu, Handan, Han, Honghui, Li, Yongmei, Wang, Liren, Chen, Geng, Ma, Xueyun, Geng, Hongquan, Huang, Wanfeng, Pang, Xiufeng, Yang, Zuozhen, Wu, Yuxuan, Siwko, Stefan, Kurita, Ryo, Nakamura, Yukio, Yang, Li, Liu, Mingyao, Li, Dali
Published in Nature biotechnology (01.07.2020)
Published in Nature biotechnology (01.07.2020)
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Engineering of a bona fide light-operated calcium channel
He, Lian, Wang, Liuqing, Zeng, Hongxiang, Tan, Peng, Ma, Guolin, Zheng, Sisi, Li, Yaxin, Sun, Lin, Dou, Fei, Siwko, Stefan, Huang, Yun, Wang, Youjun, Zhou, Yubin
Published in Nature communications (11.01.2021)
Published in Nature communications (11.01.2021)
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Journal Article
LGR4 is a receptor for RANKL and negatively regulates osteoclast differentiation and bone resorption
Luo, Jian, Yang, Zhengfeng, Ma, Yu, Yue, Zhiying, Lin, Hongyu, Qu, Guojun, Huang, Jinping, Dai, Wentao, Li, Chenghai, Zheng, Chunbing, Xu, Leqin, Chen, Huaqing, Wang, Jiqiu, Li, Dali, Siwko, Stefan, Penninger, Josef M, Ning, Guang, Xiao, Jianru, Liu, Mingyao
Published in Nature medicine (01.05.2016)
Published in Nature medicine (01.05.2016)
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Journal Article
The proton-activated G protein-coupled receptor GPR4 regulates the development of osteoarthritis via modulating CXCL12/CXCR7 signaling
Li, Rong, Guan, Zijing, Bi, Shuyan, Wang, Fanhua, He, Liang, Niu, Xin, You, Yu, Liu, Yuwei, Ding, Yi, Siwko, Stefan, Wang, Ning, Zhang, Ziming, Jin, Yunyun, Luo, Jian
Published in Cell death & disease (14.02.2022)
Published in Cell death & disease (14.02.2022)
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Journal Article
The role of GPCRs in bone diseases and dysfunctions
Luo, Jian, Sun, Peng, Siwko, Stefan, Liu, Mingyao, Xiao, Jianru
Published in Bone Research (08.07.2019)
Published in Bone Research (08.07.2019)
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Journal Article
Sex and Race-Related DNA Methylation Changes in Hepatocellular Carcinoma
Ye, Wenrui, Siwko, Stefan, Tsai, Robert Y L
Published in International journal of molecular sciences (07.04.2021)
Published in International journal of molecular sciences (07.04.2021)
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Journal Article
Lgr4 regulates mammary gland development and stem cell activity through the pluripotency transcription factor Sox2
Wang, Ying, Dong, Jie, Li, Dali, Lai, Li, Siwko, Stefan, Li, Yi, Liu, Mingyao
Published in Stem cells (Dayton, Ohio) (01.09.2013)
Published in Stem cells (Dayton, Ohio) (01.09.2013)
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Journal Article
Loss of Lgr4 inhibits differentiation, migration and apoptosis, and promotes proliferation in bone mesenchymal stem cells
Sun, Peng, Jia, Kunhang, Zheng, Chunbing, Zhu, Xinlei, Li, Jing, He, Liang, Siwko, Stefan, Xue, Feng, Liu, Mingyao, Luo, Jian
Published in Journal of cellular physiology (01.07.2019)
Published in Journal of cellular physiology (01.07.2019)
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Journal Article
Genome-wide transcriptome profiling of homologous recombination DNA repair
Peng, Guang, Chun-Jen Lin, Curtis, Mo, Wei, Dai, Hui, Park, Yun-Yong, Kim, Soo Mi, Peng, Yang, Mo, Qianxing, Siwko, Stefan, Hu, Ruozhen, Lee, Ju-Seog, Hennessy, Bryan, Hanash, Samir, Mills, Gordon B., Lin, Shiaw-Yih
Published in Nature communications (20.02.2014)
Published in Nature communications (20.02.2014)
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Journal Article
Maternal high‐fat diet disrupted one‐carbon metabolism in offspring, contributing to nonalcoholic fatty liver disease
Peng, Hui, Xu, Huiting, Wu, Jie, Li, Jiangyuan, Zhou, Yi, Ding, Zehuan, Siwko, Stefan K., Yuan, Xianglin, Schalinske, Kevin L., Alpini, Gianfranco, Zhang, Ke K., Xie, Linglin
Published in Liver international (01.06.2021)
Published in Liver international (01.06.2021)
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Journal Article
Dual Targeting of Bile Acid Receptor‐1 (TGR5) and Farnesoid X Receptor (FXR) Prevents Estrogen‐Dependent Bone Loss in Mice
Li, Zhenxi, Huang, Jinping, Wang, Fanhua, Li, Wenjun, Wu, Xian, Zhao, Chenglong, Zhao, Jian, Wei, Haifeng, Wu, Zhipeng, Qian, Ming, Sun, Peng, He, Liang, Jin, Yunyun, Tang, Jie, Qiu, Wenwei, Siwko, Stefan, Liu, Mingyao, Luo, Jian, Xiao, Jianru
Published in Journal of bone and mineral research (01.04.2019)
Published in Journal of bone and mineral research (01.04.2019)
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Journal Article
RSPO2 and RANKL signal through LGR4 to regulate osteoclastic premetastatic niche formation and bone metastasis
Yue, Zhiying, Niu, Xin, Yuan, Zengjin, Qin, Qin, Jiang, Wenhao, He, Liang, Gao, Jingduo, Ding, Yi, Liu, Yanxi, Xu, Ziwei, Li, Zhenxi, Yang, Zhengfeng, Li, Rong, Xue, Xiwen, Gao, Yankun, Yue, Fei, Zhang, Xiang H-F, Hu, Guohong, Wang, Yi, Li, Yi, Chen, Geng, Siwko, Stefan, Gartland, Alison, Wang, Ning, Xiao, Jianru, Liu, Mingyao, Luo, Jian
Published in The Journal of clinical investigation (18.01.2022)
Published in The Journal of clinical investigation (18.01.2022)
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Journal Article
ADP/P2Y1 aggravates inflammatory bowel disease through ERK5-mediated NLRP3 inflammasome activation
Zhang, Chengfei, Qin, Juliang, Zhang, Su, Zhang, Na, Tan, Binhe, Siwko, Stefan, Zhang, Ying, Wang, Qin, Chen, Jinlian, Qian, Min, Liu, Mingyao, Du, Bing
Published in Mucosal immunology (01.11.2020)
Published in Mucosal immunology (01.11.2020)
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Journal Article
Leucine-rich repeat–containing G protein–coupled receptor 4 (Lgr4) is necessary for prostate cancer metastasis via epithelial–mesenchymal transition
Luo, Weijia, Tan, Peng, Rodriguez, Melissa, He, Lian, Tan, Kunrong, Zeng, Li, Siwko, Stefan, Liu, Mingyao
Published in The Journal of biological chemistry (15.09.2017)
Published in The Journal of biological chemistry (15.09.2017)
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Journal Article
Increasing targeting scope of adenosine base editors in mouse and rat embryos through fusion of TadA deaminase with Cas9 variants
Yang, Lei, Zhang, Xiaohui, Wang, Liren, Yin, Shuming, Zhu, Biyun, Xie, Ling, Duan, Qiuhui, Hu, Huiqiong, Zheng, Rui, Wei, Yu, Peng, Liangyue, Han, Honghui, Zhang, Jiqin, Qiu, Wenjuan, Geng, Hongquan, Siwko, Stefan, Zhang, Xueli, Liu, Mingyao, Li, Dali
Published in Protein & cell (01.09.2018)
Published in Protein & cell (01.09.2018)
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Journal Article
Kisspeptin-10 binding to Gpr54 in osteoclasts prevents bone loss by activating Dusp18-mediated dephosphorylation of Src
Li, Zhenxi, Yang, Xinghai, Fu, Ruifeng, Wu, Zhipeng, Xu, Shengzhao, Jiao, Jian, Qian, Ming, Zhang, Long, Wu, Chunbiao, Xie, Tianying, Yao, Jiqiang, Wu, Zhixiang, Li, Wenjun, Ma, Guoli, You, Yu, Chen, Yihua, Zhang, Han-kun, Cheng, Yiyun, Tang, Xiaolong, Wu, Pengfei, Lian, Gewei, Wei, Haifeng, Zhao, Jian, Xu, Jianrong, Ai, Lianzhong, Siwko, Stefan, Wang, Yue, Ding, Jin, Song, Gaojie, Luo, Jian, Liu, Mingyao, Xiao, Jianru
Published in Nature communications (12.02.2024)
Published in Nature communications (12.02.2024)
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Journal Article
Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses
Xiong, Qingqing, Huang, Hongjun, Wang, Ning, Chen, Ruoyu, Chen, Naiyang, Han, Honghui, Wang, Qin, Siwko, Stefan, Liu, Mingyao, Qian, Min, Du, Bing
Published in Frontiers in immunology (02.10.2018)
Published in Frontiers in immunology (02.10.2018)
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Journal Article
KiSS1 and its G-protein-coupled receptor GPR54 in cancer development and metastasis
Cho, Sung-Gook, Li, Dali, Tan, Kunrong, Siwko, Stefan K., Liu, Mingyao
Published in Cancer and metastasis reviews (01.12.2012)
Published in Cancer and metastasis reviews (01.12.2012)
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Journal Article
Optogenetic Control of Non‐Apoptotic Cell Death
He, Lian, Huang, Zixian, Huang, Kai, Chen, Rui, Nguyen, Nhung T., Wang, Rui, Cai, Xiaoli, Huang, Zhiquan, Siwko, Stefan, Walker, Joel R., Han, Gang, Zhou, Yubin, Jing, Ji
Published in Advanced science (01.07.2021)
Published in Advanced science (01.07.2021)
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