Identification of GLPG/ABBV-2737, a Novel Class of Corrector, Which Exerts Functional Synergy With Other CFTR Modulators
de Wilde, Gert, Gees, Maarten, Musch, Sara, Verdonck, Katleen, Jans, Mia, Wesse, Anne-Sophie, Singh, Ashvani K, Hwang, Tzyh-Chang, Christophe, Thierry, Pizzonero, Mathieu, Van der Plas, Steven, Desroy, Nicolas, Cowart, Marlon, Stouten, Pieter, Nelles, Luc, Conrath, Katja
Published in Frontiers in pharmacology (09.05.2019)
Published in Frontiers in pharmacology (09.05.2019)
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Journal Article
Bicarbonate and chloride secretion in Calu-3 human airway epithelial cells
Devor, D C, Singh, A K, Lambert, L C, DeLuca, A, Frizzell, R A, Bridges, R J
Published in The Journal of general physiology (01.05.1999)
Published in The Journal of general physiology (01.05.1999)
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Journal Article
Therapeutic approaches to CFTR dysfunction: From discovery to drug development
Li, Hongyu, Pesce, Emanuela, Sheppard, David N., Singh, Ashvani K., Pedemonte, Nicoletta
Published in Journal of cystic fibrosis (01.03.2018)
Published in Journal of cystic fibrosis (01.03.2018)
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Journal Article
Novel Correctors and Potentiators Enhance Translational Readthrough in CFTR Nonsense Mutations
Mutyam, Venkateshwar, Sharma, Jyoti, Li, Yao, Peng, Ning, Chen, Jianguo, Tang, Li Ping, Falk Libby, Emily, Singh, Ashvani K, Conrath, Katja, Rowe, Steven M
Published in American journal of respiratory cell and molecular biology (01.05.2021)
Published in American journal of respiratory cell and molecular biology (01.05.2021)
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Journal Article
Biological Characterization of F508delCFTR Protein Processing by the CFTR Corrector ABBV-2222/GLPG2222
Singh, Ashvani K, Fan, Yihong, Balut, Corina, Alani, Sara, Manelli, Arlene M, Swensen, Andrew M, Jia, Ying, Neelands, Torben R, Vortherms, Timothy A, Liu, Bo, Searle, Xenia B, Wang, Xueqing, Gao, Wenqing, Hwang, Tzyh-Chang, Ren, Hong Y, Cyr, Douglas, Kym, Philip R, Conrath, Katja, Tse, Chris
Published in The Journal of pharmacology and experimental therapeutics (01.01.2020)
Published in The Journal of pharmacology and experimental therapeutics (01.01.2020)
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Journal Article
Estrogen Inhibition of Cystic Fibrosis Transmembrane Conductance Regulator-Mediated Chloride Secretion
Singh, A K, Schultz, B D, Katzenellenbogen, J A, Price, E M, Bridges, R J, Bradbury, N A
Published in The Journal of pharmacology and experimental therapeutics (01.10.2000)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.2000)
Journal Article
Neurotransmitter-stimulated ion transport by cultured porcine vas deferens epithelium
Sedlacek, R L, Carlin, R W, Singh, A K, Schultz, B D
Published in American journal of physiology. Renal physiology (01.09.2001)
Published in American journal of physiology. Renal physiology (01.09.2001)
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Journal Article
Transepithelial fluctuation analysis of chloride secretion
Singh, Ashvani K., Schultz, Bruce D., van Driessche, Willy, Bridges, Robert J.
Published in Journal of cystic fibrosis (01.08.2004)
Published in Journal of cystic fibrosis (01.08.2004)
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Journal Article
MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
SINGH ASHVANI K, GROOTENHUIS PETER D J, VAN GOOR FREDRICK F, ZHOU JINGLAN, HAZLEWOOD ANNA R, HADIDA RUAH SARAH S, JASON MCCARTNEY
Year of Publication 30.03.2017
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Year of Publication 30.03.2017
Patent
MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS
SINGH ASHVANI K, GROOTENHUIS PETER D J, VAN GOOR FREDRICK F, ZHOU JINGLAN, HAZLEWOOD ANNA R, HADIDA RUAH SARAH S, JASON MCCARTNEY
Year of Publication 01.10.2015
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Year of Publication 01.10.2015
Patent
Benzimidazolone Activators of Chloride Secretion: Potential Therapeutics for Cystic Fibrosis and Chronic Obstructive Pulmonary Disease
Singh, S, Syme, C A, Singh, A K, Devor, D C, Bridges, R J
Published in The Journal of pharmacology and experimental therapeutics (01.02.2001)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.2001)
Journal Article
Inhibitory effect of silibinin on ligand binding to erbB1 and associated mitogenic signaling, growth, and DNA synthesis in advanced human prostate carcinoma cells
Sharma, Yogesh, Agarwal, Chapla, Singh, Ashvani K., Agarwal, Rajesh
Published in Molecular carcinogenesis (2001)
Published in Molecular carcinogenesis (2001)
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Journal Article
Alchemy 2000
KONDRU, RAMA K, SINGH, ASHVANI K
Published in Science (American Association for the Advancement of Science) (16.06.2000)
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Published in Science (American Association for the Advancement of Science) (16.06.2000)
Journal Article
Stimulation of Cl(-) secretion by chlorzoxazone
Singh, A K, Devor, D C, Gerlach, A C, Gondor, M, Pilewski, J M, Bridges, R J
Published in The Journal of pharmacology and experimental therapeutics (01.02.2000)
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Published in The Journal of pharmacology and experimental therapeutics (01.02.2000)
Journal Article