Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer
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Published in Nature medicine (01.04.2019)
Published in Nature medicine (01.04.2019)
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Enhancer RNA m6A methylation facilitates transcriptional condensate formation and gene activation
Lee, Joo-Hyung, Wang, Ruoyu, Xiong, Feng, Krakowiak, Joanna, Liao, Zian, Nguyen, Phuoc T., Moroz-Omori, Elena V., Shao, Jiaofang, Zhu, Xiaoyu, Bolt, Michael J., Wu, Haoyi, Singh, Pankaj K., Bi, Mingjun, Shi, Caleb J., Jamal, Naadir, Li, Guojie, Mistry, Ragini, Jung, Sung Yun, Tsai, Kuang-Lei, Ferreon, Josephine C., Stossi, Fabio, Caflisch, Amedeo, Liu, Zhijie, Mancini, Michael A., Li, Wenbo
Published in Molecular cell (19.08.2021)
Published in Molecular cell (19.08.2021)
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Discovery of novel functionalized 1,2,4-triazoles as PARP-1 inhibitors in breast cancer: Design, synthesis and antitumor activity evaluation
Boraei, Ahmed T.A., Singh, Pankaj K., Sechi, Mario, Satta, Sandro
Published in European journal of medicinal chemistry (15.11.2019)
Published in European journal of medicinal chemistry (15.11.2019)
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The human AP-endonuclease 1 (APE1) is a DNA G-quadruplex structure binding protein and regulates KRAS expression in pancreatic ductal adenocarcinoma cells
Pramanik, Suravi, Chen, Yingling, Song, Heyu, Khutsishvili, Irine, Marky, Luis A, Ray, Sutapa, Natarajan, Amarnath, Singh, Pankaj K, Bhakat, Kishor K
Published in Nucleic acids research (08.04.2022)
Published in Nucleic acids research (08.04.2022)
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De Novo Lipid Synthesis Facilitates Gemcitabine Resistance through Endoplasmic Reticulum Stress in Pancreatic Cancer
Tadros, Saber, Shukla, Surendra K, King, Ryan J, Gunda, Venugopal, Vernucci, Enza, Abrego, Jaime, Chaika, Nina V, Yu, Fang, Lazenby, Audrey J, Berim, Lyudmyla, Grem, Jean, Sasson, Aaron R, Singh, Pankaj K
Published in Cancer research (Chicago, Ill.) (15.10.2017)
Published in Cancer research (Chicago, Ill.) (15.10.2017)
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O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
Li, Tianliang, Li, Xinghui, Attri, Kuldeep S., Liu, Changhong, Li, Lupeng, Herring, Laura E., Asara, John M., Lei, Yu L., Singh, Pankaj K., Gao, Chengjiang, Wen, Haitao
Published in Cell host & microbe (12.12.2018)
Published in Cell host & microbe (12.12.2018)
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O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3
Li, Xinghui, Gong, Wei, Wang, Hao, Li, Tianliang, Attri, Kuldeep S., Lewis, Robert E., Kalil, Andre C., Bhinderwala, Fatema, Powers, Robert, Yin, Guowei, Herring, Laura E., Asara, John M., Lei, Yu L., Yang, Xiaoyong, Rodriguez, Diego A., Yang, Mao, Green, Douglas R., Singh, Pankaj K., Wen, Haitao
Published in Immunity (Cambridge, Mass.) (19.03.2019)
Published in Immunity (Cambridge, Mass.) (19.03.2019)
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Monocyte metabolic reprogramming promotes pro-inflammatory activity and Staphylococcus aureus biofilm clearance
Yamada, Kelsey J, Heim, Cortney E, Xi, Xinyuan, Attri, Kuldeep S, Wang, Dezhen, Zhang, Wenting, Singh, Pankaj K, Bronich, Tatiana K, Kielian, Tammy
Published in PLoS pathogens (06.03.2020)
Published in PLoS pathogens (06.03.2020)
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GOT1-Mediated Anaplerotic Glutamine Metabolism Regulates Chronic Acidosis Stress In Pancreatic Cancer Cells
Abrego, Jaime, Gunda, Venugopal, Vernucci, Enza, Shukla, Surendra K, King, Ryan J, Dasgupta, Aneesha, Goode, Gennifer, Murthy, Divya, Yu, Fang, Singh, Pankaj K
Published in Cancer letters (01.08.2017)
Published in Cancer letters (01.08.2017)
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The distinct metabolic phenotype of lung squamous cell carcinoma defines selective vulnerability to glycolytic inhibition
Goodwin, Justin, Neugent, Michael L, Lee, Shin Yup, Choe, Joshua H, Choi, Hyunsung, Jenkins, Dana M R, Ruthenborg, Robin J, Robinson, Maddox W, Jeong, Ji Yun, Wake, Masaki, Abe, Hajime, Takeda, Norihiko, Endo, Hiroko, Inoue, Masahiro, Xuan, Zhenyu, Yoo, Hyuntae, Chen, Min, Ahn, Jung-Mo, Minna, John D, Helke, Kristi L, Singh, Pankaj K, Shackelford, David B, Kim, Jung-Whan
Published in Nature communications (26.05.2017)
Published in Nature communications (26.05.2017)
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Sonic Hedgehog Promotes Desmoplasia in Pancreatic Cancer
BAILEY, Jennifer M, SWANSON, Benjamin J, HAMADA, Tomofumi, EGGERS, John P, SINGH, Pankaj K, CAFFERY, Thomas, OUELLETTE, Michel M, HOLLINGSWORTH, Michael A
Published in Clinical cancer research (01.10.2008)
Published in Clinical cancer research (01.10.2008)
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Metabolic Rewiring by Loss of Sirt5 Promotes Kras-Induced Pancreatic Cancer Progression
Hu, Tuo, Shukla, Surendra K., Vernucci, Enza, He, Chunbo, Wang, Dezhen, King, Ryan J., Jha, Kanupriya, Siddhanta, Kasturi, Mullen, Nicholas J., Attri, Kuldeep S., Murthy, Divya, Chaika, Nina V., Thakur, Ravi, Mulder, Scott E., Pacheco, Camila G., Fu, Xiao, High, Robin R., Yu, Fang, Lazenby, Audrey, Steegborn, Clemens, Lan, Ping, Mehla, Kamiya, Rotili, Dante, Chaudhary, Sarika, Valente, Sergio, Tafani, Marco, Mai, Antonello, Auwerx, Johan, Verdin, Eric, Tuveson, David, Singh, Pankaj K.
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.11.2021)
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Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments
Lin, Shengchen, Huang, Chongbiao, Gunda, Venugopal, Sun, Jianwei, Chellappan, Srikumar P., Li, Zengxun, Izumi, Victoria, Fang, Bin, Koomen, John, Singh, Pankaj K., Hao, Jihui, Yang, Shengyu
Published in Cell reports (Cambridge) (10.09.2019)
Published in Cell reports (Cambridge) (10.09.2019)
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MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer
Chaika, Nina V, Gebregiworgis, Teklab, Lewallen, Michelle E, Purohit, Vinee, Radhakrishnan, Prakash, Liu, Xiang, Zhang, Bo, Mehla, Kamiya, Brown, Roger B, Caffrey, Thomas, Yu, Fang, Johnson, Keith R, Powers, Robert, Hollingsworth, Michael A, Singh, Pankaj K
Published in Proceedings of the National Academy of Sciences - PNAS (21.08.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (21.08.2012)
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Nanotechnological Advances for Nose to Brain Delivery of Therapeutics to Improve the Parkinson Therapy
Khatri, Dharmendra K, Preeti, Kumari, Tonape, Shivraj, Bhattacharjee, Sheoshree, Patel, Monica, Shah, Saurabh, Singh, Pankaj K, Srivastava, Saurabh, Gugulothu, Dalapathi, Vora, Lalitkumar, Singh, Shashi B
Published in Current neuropharmacology (01.01.2023)
Published in Current neuropharmacology (01.01.2023)
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MUC1 facilitates metabolomic reprogramming in triple-negative breast cancer
Goode, Gennifer, Gunda, Venugopal, Chaika, Nina V, Purohit, Vinee, Yu, Fang, Singh, Pankaj K
Published in PloS one (02.05.2017)
Published in PloS one (02.05.2017)
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