enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity
Barbosa, Maria Thereza P, Soares, Sandra M, Novak, Colleen M, Sinclair, David, Levine, James A, Aksoy, Pinar, Chini, Eduardo Nunes
Published in The FASEB journal (01.11.2007)
Published in The FASEB journal (01.11.2007)
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Loss of epigenetic information as a cause of mammalian aging
Yang, Jae-Hyun, Hayano, Motoshi, Griffin, Patrick T., Amorim, João A., Bonkowski, Michael S., Apostolides, John K., Salfati, Elias L., Blanchette, Marco, Munding, Elizabeth M., Bhakta, Mital, Chew, Yap Ching, Guo, Wei, Yang, Xiaojing, Maybury-Lewis, Sun, Tian, Xiao, Ross, Jaime M., Coppotelli, Giuseppe, Meer, Margarita V., Rogers-Hammond, Ryan, Vera, Daniel L., Lu, Yuancheng Ryan, Pippin, Jeffrey W., Creswell, Michael L., Dou, Zhixun, Xu, Caiyue, Mitchell, Sarah J., Das, Abhirup, O’Connell, Brendan L., Thakur, Sachin, Kane, Alice E., Su, Qiao, Mohri, Yasuaki, Nishimura, Emi K., Schaevitz, Laura, Garg, Neha, Balta, Ana-Maria, Rego, Meghan A., Gregory-Ksander, Meredith, Jakobs, Tatjana C., Zhong, Lei, Wakimoto, Hiroko, El Andari, Jihad, Grimm, Dirk, Mostoslavsky, Raul, Wagers, Amy J., Tsubota, Kazuo, Bonasera, Stephen J., Palmeira, Carlos M., Seidman, Jonathan G., Seidman, Christine E., Wolf, Norman S., Kreiling, Jill A., Sedivy, John M., Murphy, George F., Green, Richard E., Garcia, Benjamin A., Berger, Shelley L., Oberdoerffer, Philipp, Shankland, Stuart J., Gladyshev, Vadim N., Ksander, Bruce R., Pfenning, Andreas R., Rajman, Luis A., Sinclair, David A.
Published in Cell (19.01.2023)
Published in Cell (19.01.2023)
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Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty
Schultz, Michael B., Kane, Alice E., Mitchell, Sarah J., MacArthur, Michael R., Warner, Elisa, Vogel, David S., Mitchell, James R., Howlett, Susan E., Bonkowski, Michael S., Sinclair, David A.
Published in Nature communications (08.10.2020)
Published in Nature communications (08.10.2020)
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SIRT1 mRNA Expression May Be Associated With Energy Expenditure and Insulin Sensitivity
RUTANEN, Jarno, YALURI, Nagendra, ELLIOTT, Peter, WESTPHAL, Christoph, AUWERX, Johan, LAAKSO, Markku, MODI, Shalem, PIHLAJAMÄKI, Jussi, VÄNTTINEN, Markku, ITKONEN, Paula, KAINULAINEN, Sakari, YAMAMOTO, Hiroyasu, LAGOUGE, Marie, SINCLAIR, David A
Published in Diabetes (New York, N.Y.) (01.04.2010)
Published in Diabetes (New York, N.Y.) (01.04.2010)
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SIRT1 Limits Adipocyte Hyperplasia through c-Myc Inhibition
Abdesselem, Houari, Madani, Aisha, Hani, Ahmad, Al-Noubi, Muna, Goswami, Neha, Ben Hamidane, Hisham, Billing, Anja M., Pasquier, Jennifer, Bonkowski, Michael S., Halabi, Najeeb, Dalloul, Rajaa, Sheriff, Mohamed Z., Mesaeli, Nasrin, ElRayess, Mohamed, Sinclair, David A., Graumann, Johannes, Mazloum, Nayef A.
Published in The Journal of biological chemistry (29.01.2016)
Published in The Journal of biological chemistry (29.01.2016)
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The Soluble Adenylyl Cyclase Inhibitor LRE1 Prevents Hepatic Ischemia/Reperfusion Damage Through Improvement of Mitochondrial Function
Teodoro, João S, Amorim, João A, Machado, Ivo F, Castela, Ana C, Steegborn, Clemens, Sinclair, David A, Rolo, Anabela P, Palmeira, Carlos M
Published in International journal of molecular sciences (11.07.2020)
Published in International journal of molecular sciences (11.07.2020)
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Sirtuin1 over-expression does not impact retinal vascular and neuronal degeneration in a mouse model of oxygen-induced retinopathy
Michan, Shaday, Juan, Aimee M, Hurst, Christian G, Cui, Zhenghao, Evans, Lucy P, Hatton, Colman J, Pei, Dorothy T, Ju, Meihua, Sinclair, David A, Smith, Lois E H, Chen, Jing
Published in PloS one (08.01.2014)
Published in PloS one (08.01.2014)
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Altered expression of somatostatin signaling molecules and clock genes in the hippocampus of subjects with substance use disorder
Valeri, Jake, O'Donovan, Sinead M, Wang, Wei, Sinclair, David, Bollavarapu, Ratna, Gisabella, Barbara, Platt, Donna, Stockmeier, Craig, Pantazopoulos, Harry
Published in Frontiers in neuroscience (07.09.2022)
Published in Frontiers in neuroscience (07.09.2022)
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SIRT2 transgenic over‐expression does not impact lifespan in mice
Wu, Lindsay E., Fiveash, Corrine E., Bentley, Nicholas L., Kang, Myung‐Jin, Govindaraju, Hemna, Barbour, Jayne A., Wilkins, Brendan P., Hancock, Sarah E., Madawala, Romanthi, Das, Abhijit, Massudi, Hassina, Li, Catherine, Kim, Lynn‐Jee, Wong, Ashley S. A., Marinova, Maria B., Sultani, Ghazal, Das, Abhirup, Youngson, Neil A., Le Couteur, David G., Sinclair, David A., Turner, Nigel
Published in Aging cell (01.12.2023)
Published in Aging cell (01.12.2023)
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Characterization of murine SIRT3 transcript variants and corresponding protein products
Yang, Yongjie, Hubbard, Basil P., Sinclair, David A., Tong, Qiang
Published in Journal of cellular biochemistry (01.11.2010)
Published in Journal of cellular biochemistry (01.11.2010)
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Biochemical characterization, localization, and tissue distribution of the longer form of mouse SIRT3
Jin, Lei, Galonek, Heidi, Israelian, Kristine, Choy, Wendy, Morrison, Michael, Xia, Yu, Wang, Xiaohong, Xu, Yihua, Yang, Yuecheng, Smith, Jesse J., Hoffmann, Ethan, Carney, David P., Perni, Robert B., Jirousek, Michael R., Bemis, Jean E., Milne, Jill C., Sinclair, David A., Westphal, Christoph H.
Published in Protein science (01.03.2009)
Published in Protein science (01.03.2009)
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Mechanisms, pathways and strategies for rejuvenation through epigenetic reprogramming
Cipriano, Andrea, Moqri, Mahdi, Maybury-Lewis, Sun Y, Rogers-Hammond, Ryan, de Jong, Tineke Anna, Parker, Alexander, Rasouli, Sajede, Schöler, Hans Robert, Sinclair, David A, Sebastiano, Vittorio
Published in Nature aging (01.01.2024)
Published in Nature aging (01.01.2024)
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Administration of Nicotinamide Mononucleotide (NMN) Reduces Metabolic Impairment in Male Mouse Offspring from Obese Mothers
Uddin, Golam M, Youngson, Neil A, Chowdhury, Sabiha S, Hagan, Christopher, Sinclair, David A, Morris, Margaret J
Published in Cells (Basel, Switzerland) (25.03.2020)
Published in Cells (Basel, Switzerland) (25.03.2020)
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Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy
Armour, Sean M, Baur, Joseph A, Hsieh, Sherry N, Land-Bracha, Abigail, Thomas, Sheila M, Sinclair, David A
Published in Aging (Albany, NY.) (03.06.2009)
Published in Aging (Albany, NY.) (03.06.2009)
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Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes
Riepsamen, Angelique, Wu, Lindsay, Lau, Laurin, Listijono, Dave, Ledger, William, Sinclair, David, Homer, Hayden
Published in PloS one (04.05.2015)
Published in PloS one (04.05.2015)
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