SRT1720 improves survival and healthspan of obese mice
Minor, Robin K, Baur, Joseph A, Gomes, Ana P, Ward, Theresa M, Csiszar, Anna, Mercken, Evi M, Abdelmohsen, Kotb, Shin, Yu-Kyong, Canto, Carles, Scheibye-Knudsen, Morten, Krawczyk, Melissa, Irusta, Pablo M, Martín-Montalvo, Alejandro, Hubbard, Basil P, Zhang, Yongqing, Lehrmann, Elin, White, Alexa A, Price, Nathan L, Swindell, William R, Pearson, Kevin J, Becker, Kevin G, Bohr, Vilhelm A, Gorospe, Myriam, Egan, Josephine M, Talan, Mark I, Auwerx, Johan, Westphal, Christoph H, Ellis, James L, Ungvari, Zoltan, Vlasuk, George P, Elliott, Peter J, Sinclair, David A, de Cabo, Rafael
Published in Scientific reports (18.08.2011)
Published in Scientific reports (18.08.2011)
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Journal Article
Longitudinal analysis of biomarker data from a personalized nutrition platform in healthy subjects
Westerman, Kenneth, Reaver, Ashley, Roy, Catherine, Ploch, Margaret, Sharoni, Erin, Nogal, Bartek, Sinclair, David A, Katz, David L, Blumberg, Jeffrey B, Blander, Gil
Published in Scientific reports (02.10.2018)
Published in Scientific reports (02.10.2018)
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Journal Article
Impacts of obesity, maternal obesity and nicotinamide mononucleotide supplementation on sperm quality in mice
Youngson, Neil A, Uddin, G Mezbah, Das, Abhirup, Martinez, Carl, Connaughton, Haley S, Whiting, Sara, Yu, Josephine, Sinclair, David A, Aitken, R John, Morris, Margaret J
Published in Reproduction (Cambridge, England) (01.08.2019)
Published in Reproduction (Cambridge, England) (01.08.2019)
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Journal Article
Resveratrol accelerates erythroid maturation by activation of FoxO3 and ameliorates anemia in beta-thalassemic mice
Franco, Sara Santos, De Falco, Luigia, Ghaffari, Saghi, Brugnara, Carlo, Sinclair, David A, Matte', Alessandro, Iolascon, Achille, Mohandas, Narla, Bertoldi, Mariarita, An, Xiuli, Siciliano, Angela, Rimmelé, Pauline, Cappellini, Maria Domenica, Michan, Shaday, Zoratti, Elisa, Anne, Janin, De Franceschi, Lucia
Published in Haematologica (Roma) (01.02.2014)
Published in Haematologica (Roma) (01.02.2014)
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Voluntary exercise normalizes the proteomic landscape in muscle and brain and improves the phenotype of progeroid mice
Ross, Jaime M., Coppotelli, Giuseppe, Branca, Rui M., Kim, Kyung M., Lehtiö, Janne, Sinclair, David A., Olson, Lars
Published in Aging cell (01.12.2019)
Published in Aging cell (01.12.2019)
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Acetylation of the C Terminus of Ku70 by CBP and PCAF Controls Bax-Mediated Apoptosis
Cohen, Haim Y, Lavu, Siva, Bitterman, Kevin J, Hekking, Brian, Imahiyerobo, Thomas A, Miller, Christine, Frye, Roy, Ploegh, Hidde, Kessler, Benedikt M, Sinclair, David A
Published in Molecular cell (12.03.2004)
Published in Molecular cell (12.03.2004)
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Journal Article
The Ratio of Macronutrients, Not Caloric Intake, Dictates Cardiometabolic Health, Aging, and Longevity in Ad Libitum-Fed Mice
Solon-Biet, Samantha M., McMahon, Aisling C., Ballard, J. William O., Ruohonen, Kari, Wu, Lindsay E., Cogger, Victoria C., Warren, Alessandra, Huang, Xin, Pichaud, Nicolas, Melvin, Richard G., Gokarn, Rahul, Khalil, Mamdouh, Turner, Nigel, Cooney, Gregory J., Sinclair, David A., Raubenheimer, David, Le Couteur, David G., Simpson, Stephen J.
Published in Cell metabolism (03.03.2020)
Published in Cell metabolism (03.03.2020)
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Journal Article
Sustained Vision Recovery by OSK Gene Therapy in a Mouse Model of Glaucoma
Karg, Margarete M, Lu, Yuancheng Ryan, Refaian, Nasrin, Cameron, James, Hoffmann, Emma, Hoppe, Cindy, Shirahama, Shintaro, Shah, Madhura, Krasniqi, Drenushe, Krishnan, Anitha, Shrestha, Maleeka, Guo, Yinjie, Cermak, Jennifer M, Walthier, Michel, Broniowska, Kasia, Rosenzweig-Lipson, Sharon, Gregory-Ksander, Meredith, Sinclair, David A, Ksander, Bruce R
Published in Cellular reprogramming (01.12.2023)
Published in Cellular reprogramming (01.12.2023)
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Extracellular Vesicles for the Treatment of Radiation-Induced Normal Tissue Toxicity in the Lung
Montay-Gruel, Pierre, Zhu, Yafeng, Petit, Benoit, Leavitt, Ron, Warn, Mike, Giedzinski, Erich, Ollivier, Jonathan, Sinclair, David A, Vozenin, Marie-Catherine, Limoli, Charles L
Published in Frontiers in oncology (02.03.2021)
Published in Frontiers in oncology (02.03.2021)
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Journal Article
Nutritional supplements for people being treated for active tuberculosis
Sinclair, David, Abba, Katharine, Grobler, Liesl, Sudarsanam, Thambu D
Published in Cochrane database of systematic reviews (09.11.2011)
Published in Cochrane database of systematic reviews (09.11.2011)
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Journal Article
Sex differences in the response to dietary restriction in rodents
Kane, Alice E, Sinclair, David A, Mitchell, James R, Mitchell, Sarah J
Published in Current opinion in physiology (01.12.2018)
Published in Current opinion in physiology (01.12.2018)
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Journal Article
Metformin improves healthspan and lifespan in mice
Martin-Montalvo, Alejandro, Mercken, Evi M., Mitchell, Sarah J., Palacios, Hector H., Mote, Patricia L., Scheibye-Knudsen, Morten, Gomes, Ana P., Ward, Theresa M., Minor, Robin K., Blouin, Marie-José, Schwab, Matthias, Pollak, Michael, Zhang, Yongqing, Yu, Yinbing, Becker, Kevin G., Bohr, Vilhelm A., Ingram, Donald K., Sinclair, David A., Wolf, Norman S., Spindler, Stephen R., Bernier, Michel, de Cabo, Rafael
Published in Nature communications (30.07.2013)
Published in Nature communications (30.07.2013)
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A High-Confidence Interaction Map Identifies SIRT1 as a Mediator of Acetylation of USP22 and the SAGA Coactivator Complex
Armour, Sean M., Bennett, Eric J., Braun, Craig R., Zhang, Xiao-Yong, McMahon, Steven B., Gygi, Steven P., Harper, J. Wade, Sinclair, David A.
Published in Molecular and Cellular Biology (01.04.2013)
Published in Molecular and Cellular Biology (01.04.2013)
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Journal Article
Extracellular matrix abnormalities in the hippocampus of subjects with substance use disorder
Valeri, Jake, Stiplosek, Charlotte, O'Donovan, Sinead M, Sinclair, David, Grant, Kathleen A, Bollavarapu, Ratna, Platt, Donna M, Stockmeier, Craig A, Gisabella, Barbara, Pantazopoulos, Harry
Published in Translational psychiatry (24.02.2024)
Published in Translational psychiatry (24.02.2024)
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IBIS: an OR ready open-source platform for image-guided neurosurgery
Drouin, Simon, Kochanowska, Anna, Kersten-Oertel, Marta, Gerard, Ian J., Zelmann, Rina, De Nigris, Dante, Bériault, Silvain, Arbel, Tal, Sirhan, Denis, Sadikot, Abbas F., Hall, Jeffery A., Sinclair, David S., Petrecca, Kevin, DelMaestro, Rolando F., Collins, D. Louis
Published in International journal for computer assisted radiology and surgery (01.03.2017)
Published in International journal for computer assisted radiology and surgery (01.03.2017)
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Publisher Correction: Age and life expectancy clocks based on machine learning analysis of mouse frailty
Schultz, Michael B., Kane, Alice E., Mitchell, Sarah J., MacArthur, Michael R., Warner, Elisa, Vogel, David S., Mitchell, James R., Howlett, Susan E., Bonkowski, Michael S., Sinclair, David A.
Published in Nature communications (08.10.2020)
Published in Nature communications (08.10.2020)
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Journal Article
enzyme CD38 (a NAD glycohydrolase, EC 3.2.2.5) is necessary for the development of diet-induced obesity
Barbosa, Maria Thereza P, Soares, Sandra M, Novak, Colleen M, Sinclair, David, Levine, James A, Aksoy, Pinar, Chini, Eduardo Nunes
Published in The FASEB journal (01.11.2007)
Published in The FASEB journal (01.11.2007)
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