Can vaccination roll-out be more equitable if population risk is taken into account?
Sinclair, David R, Maharani, Asri, Stow, Daniel, Welsh, Claire E, Matthews, Fiona E
Published in PloS one (15.11.2021)
Published in PloS one (15.11.2021)
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Journal Article
Age and generational patterns of overdose death risk from opioids and other drugs
Jalal, Hawre, Buchanich, Jeanine M., Sinclair, David R., Roberts, Mark S., Burke, Donald S.
Published in Nature medicine (01.05.2020)
Published in Nature medicine (01.05.2020)
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Journal Article
Telomere Dysfunction Induces Sirtuin Repression that Drives Telomere-Dependent Disease
Amano, Hisayuki, Chaudhury, Arindam, Rodriguez-Aguayo, Cristian, Lu, Lan, Akhanov, Viktor, Catic, Andre, Popov, Yury V., Verdin, Eric, Johnson, Hannah, Stossi, Fabio, Sinclair, David A., Nakamaru-Ogiso, Eiko, Lopez-Berestein, Gabriel, Chang, Jeffrey T., Neilson, Joel R., Meeker, Alan, Finegold, Milton, Baur, Joseph A., Sahin, Ergun
Published in Cell metabolism (04.06.2019)
Published in Cell metabolism (04.06.2019)
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Journal Article
Is it possible to identify populations experiencing material disadvantage in primary care? A feasibility study using the Clinical Practice Research Database
Davies, Laurie E, Sinclair, David R, Kingston, Andrew, Spiers, Gemma Frances, Hanratty, Barbara
Published in Journal of epidemiology and community health (1979) (03.09.2024)
Published in Journal of epidemiology and community health (1979) (03.09.2024)
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Journal Article
Selective Sirt2 inhibition by ligand-induced rearrangement of the active site
Rumpf, Tobias, Schiedel, Matthias, Karaman, Berin, Roessler, Claudia, North, Brian J., Lehotzky, Attila, Oláh, Judit, Ladwein, Kathrin I., Schmidtkunz, Karin, Gajer, Markus, Pannek, Martin, Steegborn, Clemens, Sinclair, David A., Gerhardt, Stefan, Ovádi, Judit, Schutkowski, Mike, Sippl, Wolfgang, Einsle, Oliver, Jung, Manfred
Published in Nature communications (12.02.2015)
Published in Nature communications (12.02.2015)
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Journal Article
JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks
Van Meter, Michael, Simon, Matthew, Tombline, Gregory, May, Alfred, Morello, Timothy D., Hubbard, Basil P., Bredbenner, Katie, Park, Rosa, Sinclair, David A., Bohr, Vilhelm A., Gorbunova, Vera, Seluanov, Andrei
Published in Cell reports (Cambridge) (06.09.2016)
Published in Cell reports (Cambridge) (06.09.2016)
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Journal Article
Interventions to Slow Aging in Humans: Are We Ready?
Longo, Valter D., Antebi, Adam, Bartke, Andrzej, Barzilai, Nir, Brown‐Borg, Holly M., Caruso, Calogero, Curiel, Tyler J., Cabo, Rafael, Franceschi, Claudio, Gems, David, Ingram, Donald K., Johnson, Thomas E., Kennedy, Brian K., Kenyon, Cynthia, Klein, Samuel, Kopchick, John J., Lepperdinger, Guenter, Madeo, Frank, Mirisola, Mario G., Mitchell, James R., Passarino, Giuseppe, Rudolph, Karl L., Sedivy, John M., Shadel, Gerald S., Sinclair, David A., Spindler, Stephen R., Suh, Yousin, Vijg, Jan, Vinciguerra, Manlio, Fontana, Luigi
Published in Aging cell (01.08.2015)
Published in Aging cell (01.08.2015)
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Journal Article
School-based interventions for preventing HIV, sexually transmitted infections, and pregnancy in adolescents
Mason-Jones, Amanda J, Sinclair, David, Mathews, Catherine, Kagee, Ashraf, Hillman, Alex, Lombard, Carl
Published in Cochrane database of systematic reviews (08.11.2016)
Published in Cochrane database of systematic reviews (08.11.2016)
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Journal Article
Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38: Implications for Cellular NAD+ Metabolism, Protein Acetylation, and Treatment of Metabolic Syndrome
ESCANDE, Carlos, NIN, Veronica, PRICE, Nathan L, CAPELLINI, Verena, GOMES, Ana P, BARBOSA, Maria Thereza, O'NEIL, Luke, WHITE, Thomas A, SINCLAIR, David A, CHINI, Eduardo N
Published in Diabetes (New York, N.Y.) (01.04.2013)
Published in Diabetes (New York, N.Y.) (01.04.2013)
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Journal Article
Novel feature selection methods for construction of accurate epigenetic clocks
Li, Adam, Mueller, Amber, English, Brad, Arena, Anthony, Vera, Daniel, Kane, Alice E, Sinclair, David A
Published in PLoS computational biology (01.08.2022)
Published in PLoS computational biology (01.08.2022)
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Journal Article
Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production
Longchamp, Alban, Mirabella, Teodelinda, Arduini, Alessandro, MacArthur, Michael R., Das, Abhirup, Treviño-Villarreal, J. Humberto, Hine, Christopher, Ben-Sahra, Issam, Knudsen, Nelson H., Brace, Lear E., Reynolds, Justin, Mejia, Pedro, Tao, Ming, Sharma, Gaurav, Wang, Rui, Corpataux, Jean-Marc, Haefliger, Jacques-Antoine, Ahn, Kyo Han, Lee, Chih-Hao, Manning, Brendan D., Sinclair, David A., Chen, Christopher S., Ozaki, C. Keith, Mitchell, James R.
Published in Cell (22.03.2018)
Published in Cell (22.03.2018)
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Journal Article
Nicotinamide Improves Aspects of Healthspan, but Not Lifespan, in Mice
Mitchell, Sarah J., Bernier, Michel, Aon, Miguel A., Cortassa, Sonia, Kim, Eun Young, Fang, Evandro F., Palacios, Hector H., Ali, Ahmed, Navas-Enamorado, Ignacio, Di Francesco, Andrea, Kaiser, Tamzin A., Waltz, Tyler B., Zhang, Ning, Ellis, James L., Elliott, Peter J., Frederick, David W., Bohr, Vilhelm A., Schmidt, Mark S., Brenner, Charles, Sinclair, David A., Sauve, Anthony A., Baur, Joseph A., de Cabo, Rafael
Published in Cell metabolism (06.03.2018)
Published in Cell metabolism (06.03.2018)
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Journal Article
SIRT2 induces the checkpoint kinase BubR1 to increase lifespan
North, Brian J, Rosenberg, Michael A, Jeganathan, Karthik B, Hafner, Angela V, Michan, Shaday, Dai, Jing, Baker, Darren J, Cen, Yana, Wu, Lindsay E, Sauve, Anthony A, van Deursen, Jan M, Rosenzweig, Anthony, Sinclair, David A
Published in The EMBO journal (01.07.2014)
Published in The EMBO journal (01.07.2014)
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Journal Article
The multifactorial nature of healthy brain ageing: Brain changes, functional decline and protective factors
Turrini, Sonia, Wong, Bonnie, Eldaief, Mark, Press, Daniel Z., Sinclair, David A., Koch, Giacomo, Avenanti, Alessio, Santarnecchi, Emiliano
Published in Ageing research reviews (01.07.2023)
Published in Ageing research reviews (01.07.2023)
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Journal Article
Correction: The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth
Firestein, Ron, Blander, Gil, Michan, Shaday, Oberdoerffer, Philipp, Ogino, Shuji, Campbell, Jennifer, Bhimavarapu, Anupama, Luikenhuis, Sandra, de Cabo, Rafael, Fuchs, Charles, Hahn, William C, Guarente, Leonard P, Sinclair, David A
Published in PloS one (06.06.2024)
Published in PloS one (06.06.2024)
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Journal Article
Metformin improves healthspan and lifespan in mice
Martin-Montalvo, Alejandro, Mercken, Evi M., Mitchell, Sarah J., Palacios, Hector H., Mote, Patricia L., Scheibye-Knudsen, Morten, Gomes, Ana P., Ward, Theresa M., Minor, Robin K., Blouin, Marie-José, Schwab, Matthias, Pollak, Michael, Zhang, Yongqing, Yu, Yinbing, Becker, Kevin G., Bohr, Vilhelm A., Ingram, Donald K., Sinclair, David A., Wolf, Norman S., Spindler, Stephen R., Bernier, Michel, de Cabo, Rafael
Published in Nature communications (01.07.2013)
Published in Nature communications (01.07.2013)
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