Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators
Hubbard, Basil P., Gomes, Ana P., Dai, Han, Li, Jun, Case, April W., Considine, Thomas, Riera, Thomas V., Lee, Jessica E., Yen E, Sook, Lamming, Dudley W., Pentelute, Bradley L., Schuman, Eli R., Stevens, Linda A., Ling, Alvin J. Y., Armour, Sean M., Michan, Shaday, Zhao, Huizhen, Jiang, Yong, Sweitzer, Sharon M., Blum, Charles A., Disch, Jeremy S., Ng, Pui Yee, Howitz, Konrad T., Rolo, Anabela P., Hamuro, Yoshitomo, Moss, Joel, Perni, Robert B., Ellis, James L., Vlasuk, George P., Sinclair, David A.
Published in Science (American Association for the Advancement of Science) (08.03.2013)
Published in Science (American Association for the Advancement of Science) (08.03.2013)
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The 2021 FASEB science research conference on NAD metabolism and signaling
Gorbunova, Vera, Buschbeck, Marcus, Cambronne, Xiaolu A, Chellappa, Karthikeyani, Corda, Daniela, Du, Juan, Freichel, Marc, Gigas, Jonathan, Green, Alexander E, Gu, Feng, Guberovic, Iva, Jayabalan, Aravinthkumar, Khansahib, Imrankhan, Mukherjee, Sarmistha, Seluanov, Andrei, Simon, Matthew A, Sverkeli, Lars J, Kory, Nora, Levine, Daniel C, Matic, Ivan, Nikiforov, Andrey, Rack, Johannes G M, Imai, Shin-Ichiro, Sinclair, David A, Toiber, Debra, Zhao, Yongjuan, Mostoslavsky, Raul, Kraus, Lee, Guse, Andreas H
Published in Aging (Albany, NY.) (09.12.2021)
Published in Aging (Albany, NY.) (09.12.2021)
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Dietary Restriction: Standing Up for Sirtuins [With Response]
BAUR, JOEPH A., CHEN, DANICA, CHINI, EDUARDO N., CHUA, KATRIN, COHEN, HAIM Y., DE CABO, RAFAEL, DENG, CHUXIA, DIMMELER, STEFANIE, GIUS, DAVID, GUARENTE, LEONARD P., HELFAND, STEPHEN L., IMAI, SHIN-ICHIRO, ITOH, HIROSHI, KADOWAKI, TAKASHI, KOYA, DAISUKE, LEEUWENBURGH, CHRISTIAAN, MCBURNEY, MICHAEL, NABESHIMA, YO-ICHI, NERI, CHRISTIAN, OBERDOERFFER, PHILIPP, PESTELL, RICHARD G., ROGINA, BLANKA, SADOSHIMA, JUNICHI, SARTORELLI, VITTORIO, SERRANO, MANUEL, SINCLAIR, DAVID A., STEEGBORN, CLEMENS, TATAR, MARC, TISSENBAUM, HEIDI A., TONG, QIANG, TSUBOTA, KAZUO, VAQUERO, ALEJANDRO, VERDIN, ERIC, FONTANA, LUIGI, PARTRIDGE, LINDA, LONGO, VALTER D.
Published in Science (American Association for the Advancement of Science) (27.08.2010)
Published in Science (American Association for the Advancement of Science) (27.08.2010)
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Forecasted Size of Measles Outbreaks Associated With Vaccination Exemptions for Schoolchildren
Sinclair, David R, Grefenstette, John J, Krauland, Mary G, Galloway, David D, Frankeny, Robert J, Travis, Clayton, Burke, Donald S, Roberts, Mark S
Published in JAMA network open (02.08.2019)
Published in JAMA network open (02.08.2019)
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Design, Synthesis, and Biological Evaluation of Sirtinol Analogues as Class III Histone/Protein Deacetylase (Sirtuin) Inhibitors
Mai, Antonello, Massa, Silvio, Lavu, Siva, Pezzi, Riccardo, Simeoni, Silvia, Ragno, Rino, Mariotti, Francesca R, Chiani, Francesco, Camilloni, Giorgio, Sinclair, David A
Published in Journal of medicinal chemistry (01.12.2005)
Published in Journal of medicinal chemistry (01.12.2005)
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Oxidative Priority, Meal Frequency, and the Energy Economy of Food and Activity: Implications for Longevity, Obesity, and Cardiometabolic Disease
Cronise, Raymond J, Sinclair, David A, Bremer, Andrew A
Published in Metabolic syndrome and related disorders (01.02.2017)
Published in Metabolic syndrome and related disorders (01.02.2017)
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Manipulation of a Nuclear NAD+ Salvage Pathway Delays Aging without Altering Steady-state NAD+ Levels
Anderson, Rozalyn M., Bitterman, Kevin J., Wood, Jason G., Medvedik, Oliver, Cohen, Haim, Lin, Stephen S., Manchester, Jill K., Gordon, Jeffrey I., Sinclair, David A.
Published in The Journal of biological chemistry (24.05.2002)
Published in The Journal of biological chemistry (24.05.2002)
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Analysis of 41 cancer cell lines reveals excessive allelic loss and novel mutations in the SIRT1 gene
Han, Jeehae, Hubbard, Basil P., Lee, Jaehoon, Montagna, Cristina, Lee, Han-Woong, Sinclair, David A., Suh, Yousin
Published in Cell cycle (Georgetown, Tex.) (15.01.2013)
Published in Cell cycle (Georgetown, Tex.) (15.01.2013)
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Design and synthesis of compounds that extend yeast replicative lifespan
Yang, Hongying, Baur, Joseph A., Chen, Allen, Miller, Christine, Sinclair, David A.
Published in Aging cell (01.02.2007)
Published in Aging cell (01.02.2007)
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Advanced pathological ageing should be represented in the ICD
Bischof, Evelyne, Maier, Andrea B, Lee, Kai-Fu, Zhavoronkov, Alex, Sinclair, David
Published in The Lancet. Healthy longevity (01.01.2022)
Published in The Lancet. Healthy longevity (01.01.2022)
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TIME-seq reduces time and cost of DNA methylation measurement for epigenetic clock construction
Griffin, Patrick T, Kane, Alice E, Trapp, Alexandre, Li, Jien, Arnold, Matthew, Poganik, Jesse R, Conway, Ryan J, McNamara, Maeve S, Meer, Margarita V, Hoffman, Noah, Amorim, João A, Tian, Xiao, MacArthur, Michael R, Mitchell, Sarah J, Mueller, Amber L, Carmody, Colleen, Vera, Daniel L, Kerepesi, Csaba, Ying, Kejun, Noren Hooten, Nicole, Mitchell, James R, Evans, Michele K, Gladyshev, Vadim N, Sinclair, David A
Published in Nature aging (01.02.2024)
Published in Nature aging (01.02.2024)
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GLTSCR2/PICT1 links mitochondrial stress and Myc signaling
Yoon, John C., Ling, Alvin J. Y., Isik, Meltem, Lee, Dong-Young Donna, Steinbaugh, Michael J., Sack, Laura M., Boduch, Abigail N., Blackwell, T. Keith, Sinclair, David A., Elledge, Stephen J.
Published in Proceedings of the National Academy of Sciences - PNAS (11.03.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (11.03.2014)
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