Nuclear FAK Controls Chemokine Transcription, Tregs, and Evasion of Anti-tumor Immunity
Serrels, Alan, Lund, Tom, Serrels, Bryan, Byron, Adam, McPherson, Rhoanne C., von Kriegsheim, Alexander, Gómez-Cuadrado, Laura, Canel, Marta, Muir, Morwenna, Ring, Jennifer E., Maniati, Eleni, Sims, Andrew H., Pachter, Jonathan A., Brunton, Valerie G., Gilbert, Nick, Anderton, Stephen M., Nibbs, Robert J.B., Frame, Margaret C.
Published in Cell (24.09.2015)
Published in Cell (24.09.2015)
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Journal Article
Wnt pathway activity in breast cancer sub-types and stem-like cells
Lamb, Rebecca, Ablett, Matthew P, Spence, Katherine, Landberg, Göran, Sims, Andrew H, Clarke, Robert B
Published in PloS one (04.07.2013)
Published in PloS one (04.07.2013)
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Journal Article
Human Tumor-Associated Macrophage and Monocyte Transcriptional Landscapes Reveal Cancer-Specific Reprogramming, Biomarkers, and Therapeutic Targets
Cassetta, Luca, Fragkogianni, Stamatina, Sims, Andrew H., Swierczak, Agnieszka, Forrester, Lesley M., Zhang, Hui, Soong, Daniel Y.H., Cotechini, Tiziana, Anur, Pavana, Lin, Elaine Y., Fidanza, Antonella, Lopez-Yrigoyen, Martha, Millar, Michael R., Urman, Alexandra, Ai, Zhichao, Spellman, Paul T., Hwang, E. Shelley, Dixon, J. Michael, Wiechmann, Lisa, Coussens, Lisa M., Smith, Harriet O., Pollard, Jeffrey W.
Published in Cancer cell (15.04.2019)
Published in Cancer cell (15.04.2019)
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Journal Article
MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA–DNA triplex structures
Mondal, Tanmoy, Subhash, Santhilal, Vaid, Roshan, Enroth, Stefan, Uday, Sireesha, Reinius, Björn, Mitra, Sanhita, Mohammed, Arif, James, Alva Rani, Hoberg, Emily, Moustakas, Aristidis, Gyllensten, Ulf, Jones, Steven J.M., Gustafsson, Claes M, Sims, Andrew H, Westerlund, Fredrik, Gorab, Eduardo, Kanduri, Chandrasekhar
Published in Nature communications (24.07.2015)
Published in Nature communications (24.07.2015)
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Journal Article
Microenvironmental IL1β promotes breast cancer metastatic colonisation in the bone via activation of Wnt signalling
Eyre, Rachel, Alférez, Denis G., Santiago-Gómez, Angélica, Spence, Kath, McConnell, James C., Hart, Claire, Simões, Bruno M., Lefley, Diane, Tulotta, Claudia, Storer, Joanna, Gurney, Austin, Clarke, Noel, Brown, Mick, Howell, Sacha J., Sims, Andrew H., Farnie, Gillian, Ottewell, Penelope D., Clarke, Robert B.
Published in Nature communications (01.11.2019)
Published in Nature communications (01.11.2019)
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Journal Article
Monocyte-derived macrophages promote breast cancer bone metastasis outgrowth
Ma, Ruo-Yu, Zhang, Hui, Li, Xue-Feng, Zhang, Cheng-Bin, Selli, Cigdem, Tagliavini, Giulia, Lam, Alyson D, Prost, Sandrine, Sims, Andrew H, Hu, Hai-Yan, Ying, Tianlei, Wang, Zhan, Ye, Zhaoming, Pollard, Jeffrey W, Qian, Bin-Zhi
Published in The Journal of experimental medicine (02.11.2020)
Published in The Journal of experimental medicine (02.11.2020)
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Journal Article
Patent foramen ovale closure: A prospective UK registry linked to hospital episode statistics
Willits, Iain, Keltie, Kim, Henderson, Robert, de Belder, Mark, Linker, Nicholas, Patrick, Hannah, Powell, Helen, Berry, Lee, Urwin, Samuel, Cole, Helen, Sims, Andrew J
Published in PloS one (14.07.2022)
Published in PloS one (14.07.2022)
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Journal Article
Immune Cell Gene Signatures for Profiling the Microenvironment of Solid Tumors
Nirmal, Ajit J, Regan, Tim, Shih, Barbara B, Hume, David A, Sims, Andrew H, Freeman, Tom C
Published in Cancer immunology research (01.11.2018)
Published in Cancer immunology research (01.11.2018)
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Journal Article
Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity
Simões, Bruno M., O’Brien, Ciara S., Eyre, Rachel, Silva, Andreia, Yu, Ling, Sarmiento-Castro, Aida, Alférez, Denis G., Spence, Kath, Santiago-Gómez, Angélica, Chemi, Francesca, Acar, Ahmet, Gandhi, Ashu, Howell, Anthony, Brennan, Keith, Rydén, Lisa, Catalano, Stefania, Andó, Sebastiano, Gee, Julia, Ucar, Ahmet, Sims, Andrew H., Marangoni, Elisabetta, Farnie, Gillian, Landberg, Göran, Howell, Sacha J., Clarke, Robert B.
Published in Cell reports (Cambridge) (29.09.2015)
Published in Cell reports (Cambridge) (29.09.2015)
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Journal Article
MCL-1 is a prognostic indicator and drug target in breast cancer
Campbell, Kirsteen J., Dhayade, Sandeep, Ferrari, Nicola, Sims, Andrew H., Johnson, Emma, Mason, Susan M., Dickson, Ashley, Ryan, Kevin M., Kalna, Gabriela, Edwards, Joanne, Tait, Stephen W. G., Blyth, Karen
Published in Cell death & disease (16.01.2018)
Published in Cell death & disease (16.01.2018)
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Journal Article
Neoadjuvant Therapy for Breast Cancer as a Model for Translational Research
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Book Review
Journal Article
GPER mediates the angiocrine actions induced by IGF1 through the HIF-1α/VEGF pathway in the breast tumor microenvironment
De Francesco, Ernestina M, Sims, Andrew H, Maggiolini, Marcello, Sotgia, Federica, Lisanti, Michael P, Clarke, Robert B
Published in Breast cancer research : BCR (06.12.2017)
Published in Breast cancer research : BCR (06.12.2017)
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Journal Article
Validation of a Standardised Duplex Ultrasound Classification System for the Reporting and Grading of Peripheral Arterial Disease
Huthart, Samuel, Oates, Crispian, Allen, John, Fiaschi, Kathia, Sims, Andrew J., Stansby, Gerard
Published in European journal of vascular and endovascular surgery (01.08.2022)
Published in European journal of vascular and endovascular surgery (01.08.2022)
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Journal Article
Cyclin D1, Id1 and EMT in breast cancer
Tobin, Nicholas P, Sims, Andrew H, Lundgren, Katja L, Lehn, Sophie, Landberg, Göran
Published in BMC cancer (28.09.2011)
Published in BMC cancer (28.09.2011)
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Journal Article
HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer
Jarman, Edward J, Ward, Carol, Turnbull, Arran K, Martinez-Perez, Carlos, Meehan, James, Xintaropoulou, Chrysi, Sims, Andrew H, Langdon, Simon P
Published in Breast cancer research : BCR (22.01.2019)
Published in Breast cancer research : BCR (22.01.2019)
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Journal Article
The IL1β-IL1R signaling is involved in the stimulatory effects triggered by hypoxia in breast cancer cells and cancer-associated fibroblasts (CAFs)
Lappano, Rosamaria, Talia, Marianna, Cirillo, Francesca, Rigiracciolo, Damiano Cosimo, Scordamaglia, Domenica, Guzzi, Rita, Miglietta, Anna Maria, De Francesco, Ernestina Marianna, Belfiore, Antonino, Sims, Andrew H, Maggiolini, Marcello
Published in Journal of experimental & clinical cancer research (10.08.2020)
Published in Journal of experimental & clinical cancer research (10.08.2020)
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Journal Article