A Pan-GTPase Inhibitor as a Molecular Probe
Hong, Lin, Guo, Yuna, BasuRay, Soumik, Agola, Jacob O, Romero, Elsa, Simpson, Denise S, Schroeder, Chad E, Simons, Peter, Waller, Anna, Garcia, Matthew, Carter, Mark, Ursu, Oleg, Gouveia, Kristine, Golden, Jennifer E, Aubé, Jeffrey, Wandinger-Ness, Angela, Sklar, Larry A
Published in PloS one (06.08.2015)
Published in PloS one (06.08.2015)
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Journal Article
A selective ATP-binding cassette subfamily G member 2 efflux inhibitor revealed via high-throughput flow cytometry
Strouse, J Jacob, Ivnitski-Steele, Irena, Khawaja, Hadya M, Perez, Dominique, Ricci, Jerec, Yao, Tuanli, Weiner, Warren S, Schroeder, Chad E, Simpson, Denise S, Maki, Brooks E, Li, Kelin, Golden, Jennifer E, Foutz, Terry D, Waller, Anna, Evangelisti, Annette M, Young, Susan M, Chavez, Stephanie E, Garcia, Matthew J, Ursu, Oleg, Bologa, Cristian G, Carter, Mark B, Salas, Virginia M, Gouveia, Kristine, Tegos, George P, Oprea, Tudor I, Edwards, Bruce S, Aubé, Jeffrey, Larson, Richard S, Sklar, Larry A
Published in Journal of biomolecular screening (01.01.2013)
Published in Journal of biomolecular screening (01.01.2013)
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Journal Article
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: role of the furan in affinity for opioid receptors
Simpson, Denise S., Lovell, Kimberly M., Lozama, Anthony, Han, Nina, Day, Victor W., Dersch, Christina M., Rothman, Richard B., Prisinzano, Thomas E.
Published in Organic & biomolecular chemistry (01.01.2009)
Published in Organic & biomolecular chemistry (01.01.2009)
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Journal Article
The antiproliferative and apoptotic effects of apigenin on glioblastoma cells
Stump, Trevor A, Santee, Brittany N, Williams, Lauren P, Kunze, Rachel A, Heinze, Chelsae E, Huseman, Eric D, Gryka, Rebecca J, Simpson, Denise S, Amos, Samson
Published in Journal of pharmacy and pharmacology (01.07.2017)
Published in Journal of pharmacy and pharmacology (01.07.2017)
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Journal Article
Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: New concepts in mu opioid receptor pharmacology: From a symposium on new concepts in mu-opioid pharmacology
Lamb, Kenneth, Tidgewell, Kevin, Simpson, Denise S, Bohn, Laura M, Prisinzano, Thomas E
Published in Drug and alcohol dependence (01.03.2012)
Published in Drug and alcohol dependence (01.03.2012)
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Journal Article
Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold
Flaherty, Daniel P., Simpson, Denise S., Miller, Melissa, Maki, Brooks E., Zou, Beiyan, Shi, Jie, Wu, Meng, McManus, Owen B., Aubé, Jeffrey, Li, Min, Golden, Jennifer E.
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
Published in Bioorganic & medicinal chemistry letters (15.08.2014)
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Journal Article
Quassinoids and a coumarin from Castela macrophylla (Simaroubaceae)
Jacobs, Helen, Simpson, Denise S., Reynolds, William F.
Published in Biochemical systematics and ecology (2007)
Published in Biochemical systematics and ecology (2007)
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Journal Article
A Competitive Nucleotide Binding Inhibitor: In Vitro Characterization of Rab7 GTPase Inhibition
Agola, Jacob O, Hong, Lin, Surviladze, Zurab, Ursu, Oleg, Waller, Anna, Strouse, J. Jacob, Simpson, Denise S, Schroeder, Chad E, Oprea, Tudor I, Golden, Jennifer E, Aubé, Jeffrey, Buranda, Tione, Sklar, Larry A, Wandinger-Ness, Angela
Published in ACS chemical biology (15.06.2012)
Published in ACS chemical biology (15.06.2012)
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Journal Article
Optimization of Potent and Selective Quinazolinediones: Inhibitors of Respiratory Syncytial Virus That Block RNA-Dependent RNA-Polymerase Complex Activity
Matharu, Daljit S, Flaherty, Daniel P, Simpson, Denise S, Schroeder, Chad E, Chung, Donghoon, Yan, Dan, Noah, James W, Jonsson, Colleen B, White, E. Lucile, Aubé, Jeffrey, Plemper, Richard K, Severson, William E, Golden, Jennifer E
Published in Journal of medicinal chemistry (26.12.2014)
Published in Journal of medicinal chemistry (26.12.2014)
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Journal Article
Ebselen Inhibits Hepatitis C Virus NS3 Helicase Binding to Nucleic Acid and Prevents Viral Replication
Mukherjee, Sourav, Weiner, Warren S, Schroeder, Chad E, Simpson, Denise S, Hanson, Alicia M, Sweeney, Noreena L, Marvin, Rachel K, Ndjomou, Jean, Kolli, Rajesh, Isailovic, Dragan, Schoenen, Frank J, Frick, David N
Published in ACS chemical biology (17.10.2014)
Published in ACS chemical biology (17.10.2014)
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Journal Article
The effects of herkinorin, the first mu-selective ligand from a salvinorin A-derived scaffold, in a neuroendocrine biomarker assay in nonhuman primates
Butelman, Eduardo R, Rus, Szymon, Simpson, Denise S, Wolf, Angela, Prisinzano, Thomas E, Kreek, Mary Jeanne
Published in The Journal of pharmacology and experimental therapeutics (01.10.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.10.2008)
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Journal Article
Potential Drug Abuse Therapeutics Derived from the Hallucinogenic Natural Product Salvinorin A
Prevatt-Smith, Katherine M, Lovell, Kimberly M, Simpson, Denise S, Day, Victor W, Douglas, Justin T, Bosch, Peter, Dersch, Christina M, Rothman, Richard B, Kivell, Bronwyn, Prisinzano, Thomas E
Published in MedChemComm (01.12.2011)
Published in MedChemComm (01.12.2011)
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Journal Article
Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Preparation and Opioid Receptor Activity of Salvinicin Analogues
SIMPSON, Denise S., KATAVIC, Peter L., LOZAMA, Anthony, HARDING, Wayne W., PARRISH, Damon, DESCHAMPS, Jeffrey R., DERSCH, Christina M., PARTILLA, John S., ROTHMAN, Richard B., NAVARRO, Hernan, PRISINZANO, Thomas E.
Published in Journal of medicinal chemistry (26.07.2007)
Published in Journal of medicinal chemistry (26.07.2007)
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Journal Article
Tetranortriterpenoids from Spathelia sorbifolia (Rutaceae)
Simpson, Denise S., McLean, Stewart, Reynolds, William F., Jacobs, Helen
Published in Natural product communications (01.06.2010)
Published in Natural product communications (01.06.2010)
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Journal Article
Differential effects of opioid agonists on G protein expression in CHO cells expressing cloned human opioid receptors
Xu, Heng, Wang, Xiaoying, Partilla, John S, Bishop-Mathis, Kristen, Benaderet, Tova S, Dersch, Christina M, Simpson, Denise S, Prisinzano, Thomas E, Rothman, Richard B
Published in Brain research bulletin (05.09.2008)
Published in Brain research bulletin (05.09.2008)
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Journal Article
Utilizing nature as a source of new probes for opioid pharmacology
Lovell, Kimberly M, Simpson, Denise S, Cunningham, Christopher W, Prisinzano, Thomas E
Published in Future medicinal chemistry (01.05.2009)
Published in Future medicinal chemistry (01.05.2009)
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Journal Article
Synthetic Studies of Neoclerodane Diterpenes from Salvia d ivinorum: Preparation and Opioid Receptor Activity of Salvinicin Analogues
Simpson, Denise S, Katavic, Peter L, Lozama, Anthony, Harding, Wayne W, Parrish, Damon, Deschamps, Jeffrey R, Dersch, Christina M, Partilla, John S, Rothman, Richard B, Navarro, Hernan, Prisinzano, Thomas E
Published in Journal of medicinal chemistry (26.07.2007)
Published in Journal of medicinal chemistry (26.07.2007)
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Journal Article
A new squalene-derived epoxy tri-THF diol from Spathelia glabrescens
Harding, Wayne W, Simpson, Denise S, Jacobs, Helen, McLean, Stewart, Reynolds, William F
Published in Tetrahedron letters (15.10.2001)
Published in Tetrahedron letters (15.10.2001)
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Journal Article
Antinociceptive Effects of Herkinorin, a MOP Receptor Agonist Derived from Salvinorin A in the Formalin Test in Rats: New Concepts in Mu Opioid Receptor Pharmacology
Lamb, Kenneth, Tidgewell, Kevin, Simpson, Denise S., Bohn, Laura M., Prisinzano, Thomas E.
Published in Drug and alcohol dependence (26.11.2011)
Published in Drug and alcohol dependence (26.11.2011)
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Journal Article
Identification of a novel "almost neutral" μ-opioid receptor antagonist in CHO cells expressing the cloned human μ-opioid receptor
Sally, Elliott J., Xu, Heng, Dersch, Christina M., Hsin, Ling-Wei, Chang, Li-Te, Prisinzano, Thomas E., Simpson, Denise S., Giuvelis, Denise, Rice, Kenner C., Jacobson, Arthur E., Cheng, Kejun, Bilsky, Edward J., Rothman, Richard B.
Published in Synapse (New York, N.Y.) (01.04.2010)
Published in Synapse (New York, N.Y.) (01.04.2010)
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Journal Article