The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis
Lucas, Jared M, Heinlein, Cynthia, Kim, Tom, Hernandez, Susana A, Malik, Muzdah S, True, Lawrence D, Morrissey, Colm, Corey, Eva, Montgomery, Bruce, Mostaghel, Elahe, Clegg, Nigel, Coleman, Ilsa, Brown, Christopher M, Schneider, Eric L, Craik, Charles, Simon, Julian A, Bedalov, Antonio, Nelson, Peter S
Published in Cancer discovery (01.11.2014)
Published in Cancer discovery (01.11.2014)
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Phenotypic Optimization of Urea–Thiophene Carboxamides To Yield Potent, Well Tolerated, and Orally Active Protective Agents against Aminoglycoside-Induced Hearing Loss
Chowdhury, Sarwat, Owens, Kelly N, Herr, R. Jason, Jiang, Qin, Chen, Xinchao, Johnson, Graham, Groppi, Vincent E, Raible, David W, Rubel, Edwin W, Simon, Julian A
Published in Journal of medicinal chemistry (11.01.2018)
Published in Journal of medicinal chemistry (11.01.2018)
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Discovery of Selective SIRT2 Inhibitors as Therapeutic Agents in B-Cell Lymphoma and Other Malignancies
Chowdhury, Sarwat, Sripathy, Smitha, Webster, Alyssa, Park, Angela, Lao, Uyen, Hsu, Joanne H, Loe, Taylor, Bedalov, Antonio, Simon, Julian A
Published in Molecules (Basel, Switzerland) (21.01.2020)
Published in Molecules (Basel, Switzerland) (21.01.2020)
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Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death
Owens, Kelly N, Santos, Felipe, Roberts, Brock, Linbo, Tor, Coffin, Allison B, Knisely, Anna J, Simon, Julian A, Rubel, Edwin W, Raible, David W
Published in PLoS genetics (01.02.2008)
Published in PLoS genetics (01.02.2008)
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Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes
HELTWEG, Birgit, GATBONTON, Tonibelle, BEDALOV, Antonio, SCHULER, Aaron D, POSAKONY, Jeff, HONGZHE LI, GOEHLE, Sondra, KOLLIPARA, Ramya, DEPINHO, Ronald A, YANSONG GU, SIMON, Julian A
Published in Cancer research (Chicago, Ill.) (15.04.2006)
Published in Cancer research (Chicago, Ill.) (15.04.2006)
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Long-term tracking demonstrates effectiveness of a partnership-led training program to advance the careers of biomedical researchers from underrepresented groups
Thompson, Beti, O'Connell, Mary A, Peterson, Karen, Shuster, Michele, Drennan, Marilyn, Loest, Helena, Holte, Sarah, Simon, Julian A, Unguez, Graciela A
Published in PloS one (12.12.2019)
Published in PloS one (12.12.2019)
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Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin
Jacquemont, Céline, Simon, Julian A, D'Andrea, Alan D, Taniguchi, Toshiyasu
Published in Molecular cancer (26.04.2012)
Published in Molecular cancer (26.04.2012)
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An in vivo Biomarker to Characterize Ototoxic Compounds and Novel Protective Therapeutics
Bellairs, Joseph A, Redila, Van A, Wu, Patricia, Tong, Ling, Webster, Alyssa, Simon, Julian A, Rubel, Edwin W, Raible, David W
Published in Frontiers in molecular neuroscience (18.07.2022)
Published in Frontiers in molecular neuroscience (18.07.2022)
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Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast
Gatbonton, Tonibelle, Imbesi, Maria, Nelson, Melisa, Akey, Joshua M, Ruderfer, Douglas M, Kruglyak, Leonid, Simon, Julian A, Bedalov, Antonio
Published in PLoS genetics (01.03.2006)
Published in PLoS genetics (01.03.2006)
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Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis
Tang, Xi, Mahajan, Sumit S, Nguyen, Liem T, Béliveau, François, Leduc, Richard, Simon, Julian A, Vasioukhin, Valeri
Published in Oncotarget (15.03.2014)
Published in Oncotarget (15.03.2014)
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Hair Cell Toxicity in Anti-cancer Drugs: Evaluating an Anti-cancer Drug Library for Independent and Synergistic Toxic Effects on Hair Cells Using the Zebrafish Lateral Line
Hirose, Yoshinobu, Simon, Julian A., Ou, Henry C.
Published in Journal of the Association for Research in Otolaryngology (01.12.2011)
Published in Journal of the Association for Research in Otolaryngology (01.12.2011)
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Chemical screening for hair cell loss and protection in the zebrafish lateral line
Coffin, Allison B, Ou, Henry, Owens, Kelly N, Santos, Felipe, Simon, Julian A, Rubel, Edwin W, Raible, David W
Published in Zebrafish (01.03.2010)
Published in Zebrafish (01.03.2010)
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Journal Article
Quinoline Ring Derivatives Protect Against Aminoglycoside-Induced Hair Cell Death in the Zebrafish Lateral Line
Ou, Henry C., Keating, Sarah, Wu, Patricia, Simon, Julian A., Raible, David W., Rubel, Edwin W
Published in Journal of the Association for Research in Otolaryngology (01.12.2012)
Published in Journal of the Association for Research in Otolaryngology (01.12.2012)
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