The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion
Dembitz, Vilma, Tomic, Barbara, Kodvanj, Ivan, Simon, Julian A., Bedalov, Antonio, Visnjic, Dora
Published in The Journal of biological chemistry (18.10.2019)
Published in The Journal of biological chemistry (18.10.2019)
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The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis
Lucas, Jared M, Heinlein, Cynthia, Kim, Tom, Hernandez, Susana A, Malik, Muzdah S, True, Lawrence D, Morrissey, Colm, Corey, Eva, Montgomery, Bruce, Mostaghel, Elahe, Clegg, Nigel, Coleman, Ilsa, Brown, Christopher M, Schneider, Eric L, Craik, Charles, Simon, Julian A, Bedalov, Antonio, Nelson, Peter S
Published in Cancer discovery (01.11.2014)
Published in Cancer discovery (01.11.2014)
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Identification of genetic and chemical modulators of zebrafish mechanosensory hair cell death
Owens, Kelly N, Santos, Felipe, Roberts, Brock, Linbo, Tor, Coffin, Allison B, Knisely, Anna J, Simon, Julian A, Rubel, Edwin W, Raible, David W
Published in PLoS genetics (01.02.2008)
Published in PLoS genetics (01.02.2008)
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Development of Pyrazolone and Isoxazol-5-one Cambinol Analogues as Sirtuin Inhibitors
Mahajan, Sumit S, Scian, Michele, Sripathy, Smitha, Posakony, Jeff, Lao, Uyen, Loe, Taylor K, Leko, Vid, Thalhofer, Angel, Schuler, Aaron D, Bedalov, Antonio, Simon, Julian A
Published in Journal of medicinal chemistry (24.04.2014)
Published in Journal of medicinal chemistry (24.04.2014)
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Long-term tracking demonstrates effectiveness of a partnership-led training program to advance the careers of biomedical researchers from underrepresented groups
Thompson, Beti, O'Connell, Mary A, Peterson, Karen, Shuster, Michele, Drennan, Marilyn, Loest, Helena, Holte, Sarah, Simon, Julian A, Unguez, Graciela A
Published in PloS one (12.12.2019)
Published in PloS one (12.12.2019)
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Phenotypic Optimization of Urea–Thiophene Carboxamides To Yield Potent, Well Tolerated, and Orally Active Protective Agents against Aminoglycoside-Induced Hearing Loss
Chowdhury, Sarwat, Owens, Kelly N, Herr, R. Jason, Jiang, Qin, Chen, Xinchao, Johnson, Graham, Groppi, Vincent E, Raible, David W, Rubel, Edwin W, Simon, Julian A
Published in Journal of medicinal chemistry (11.01.2018)
Published in Journal of medicinal chemistry (11.01.2018)
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Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin
Jacquemont, Céline, Simon, Julian A, D'Andrea, Alan D, Taniguchi, Toshiyasu
Published in Molecular cancer (26.04.2012)
Published in Molecular cancer (26.04.2012)
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Discovery of Selective SIRT2 Inhibitors as Therapeutic Agents in B-Cell Lymphoma and Other Malignancies
Chowdhury, Sarwat, Sripathy, Smitha, Webster, Alyssa, Park, Angela, Lao, Uyen, Hsu, Joanne H, Loe, Taylor, Bedalov, Antonio, Simon, Julian A
Published in Molecules (Basel, Switzerland) (21.01.2020)
Published in Molecules (Basel, Switzerland) (21.01.2020)
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Inhibition of vaccinia virus replication by nitazoxanide
Hickson, Sarah E., Margineantu, Daciana, Hockenbery, David M., Simon, Julian A., Geballe, Adam P.
Published in Virology (New York, N.Y.) (01.05.2018)
Published in Virology (New York, N.Y.) (01.05.2018)
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PIWI genes and piRNAs are ubiquitously expressed in mollusks and show patterns of lineage-specific adaptation
Jehn, Julia, Gebert, Daniel, Pipilescu, Frank, Stern, Sarah, Kiefer, Julian Simon Thilo, Hewel, Charlotte, Rosenkranz, David
Published in Communications biology (07.09.2018)
Published in Communications biology (07.09.2018)
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Journal Article
Fate plasticity and reprogramming in genetically distinct populations of Danio leucophores
Lewis, Victor M., Saunders, Lauren M., Larson, Tracy A., Bain, Emily J., Sturiale, Samantha L., Gur, Dvir, Chowdhury, Sarwat, Flynn, Jessica D., Allen, Michael C., Deheyn, Dimitri D., Lee, Jennifer C., Simon, Julian A., Lippincott-Schwartz, Jennifer, Raible, David W., Parichy, David M.
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (11.06.2019)
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CSF1R-Mediated Myeloid Cell Depletion Prolongs Lifespan But Aggravates Distinct Motor Symptoms in a Model of Multiple System Atrophy
Battis, Kristina, Florio, Jazmin B, Mante, Michael, Lana, Addison, Naumann, Isabel, Gauer, Carina, Lambrecht, Vera, Müller, Simon Julian, Cobo, Isidoro, Fixsen, Bethany, Kim, Ha Yeon, Masliah, Eliezer, Glass, Christopher K, Schlachetzki, Johannes C M, Rissman, Robert A, Winkler, Jürgen, Hoffmann, Alana
Published in The Journal of neuroscience (05.10.2022)
Published in The Journal of neuroscience (05.10.2022)
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Telomere length as a quantitative trait: genome-wide survey and genetic mapping of telomere length-control genes in yeast
Gatbonton, Tonibelle, Imbesi, Maria, Nelson, Melisa, Akey, Joshua M, Ruderfer, Douglas M, Kruglyak, Leonid, Simon, Julian A, Bedalov, Antonio
Published in PLoS genetics (01.03.2006)
Published in PLoS genetics (01.03.2006)
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Antitumor activity of a small-molecule inhibitor of human silent information regulator 2 enzymes
HELTWEG, Birgit, GATBONTON, Tonibelle, BEDALOV, Antonio, SCHULER, Aaron D, POSAKONY, Jeff, HONGZHE LI, GOEHLE, Sondra, KOLLIPARA, Ramya, DEPINHO, Ronald A, YANSONG GU, SIMON, Julian A
Published in Cancer research (Chicago, Ill.) (15.04.2006)
Published in Cancer research (Chicago, Ill.) (15.04.2006)
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Enhancing cancer therapeutics using size-optimized magnetic fluid hyperthermia
Khandhar, Amit P, Ferguson, R Matthew, Simon, Julian A, Krishnan, Kannan M
Published in Journal of applied physics (01.04.2012)
Published in Journal of applied physics (01.04.2012)
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Inhibition of a nutritional endosymbiont by glyphosate abolishes mutualistic benefit on cuticle synthesis in Oryzaephilus surinamensis
Kiefer, Julian Simon Thilo, Batsukh, Suvdanselengee, Bauer, Eugen, Hirota, Bin, Weiss, Benjamin, Wierz, Jürgen C., Fukatsu, Takema, Kaltenpoth, Martin, Engl, Tobias
Published in Communications biology (11.05.2021)
Published in Communications biology (11.05.2021)
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