An Integrated in Silico 3D Model-Driven Discovery of a Novel, Potent, and Selective Amidosulfonamide 5-HT1A Agonist (PRX-00023) for the Treatment of Anxiety and Depression
Becker, Oren M, Dhanoa, Dale S, Marantz, Yael, Chen, Dongli, Shacham, Sharon, Cheruku, Srinivasa, Heifetz, Alexander, Mohanty, Pradyumna, Fichman, Merav, Sharadendu, Anurag, Nudelman, Raphael, Kauffman, Michael, Noiman, Silvia
Published in Journal of medicinal chemistry (01.06.2006)
Published in Journal of medicinal chemistry (01.06.2006)
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Journal Article
G Protein-Coupled Receptors: In silico Drug Discovery in 3D
Becker, Oren M., Marantz, Yael, Shacham, Sharon, Inbal, Boaz, Heifetz, Alexander, Kalid, Ori, Bar-Haim, Shay, Warshaviak, Dora, Fichman, Merav, Noiman, Silvia, Levitt, Michael
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (03.08.2004)
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Journal Article
PREDICT modeling and in-silico screening for G-protein coupled receptors
Shacham, Sharon, Marantz, Yael, Bar-Haim, Shay, Kalid, Ori, Warshaviak, Dora, Avisar, Noa, Inbal, Boaz, Heifetz, Alexander, Fichman, Merav, Topf, Maya, Naor, Zvi, Noiman, Silvia, Becker, Oren M.
Published in Proteins, structure, function, and bioinformatics (01.10.2004)
Published in Proteins, structure, function, and bioinformatics (01.10.2004)
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Journal Article
VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux
Mohler, Eric G., Shacham, Sharon, Noiman, Silvia, Lezoualc'h, Frank, Robert, Sylvain, Gastineau, Monique, Rutkowski, Joseph, Marantz, Yael, Dumuis, Aline, Bockaert, Joel, Gold, Paul E., Ragozzino, Michael E.
Published in Neuropharmacology (01.09.2007)
Published in Neuropharmacology (01.09.2007)
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Journal Article
VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux
Mohler, Eric G, Shacham, Sharon, Noiman, Silvia, Lezoualc'h, Frank, Robert, Sylvain, Gastineau, Monique, Rutkowski, Joseph, Marantz, Yael, Dumuis, Aline, Bockaert, Joel, Gold, Paul E, Ragozzino, Michael E
Published in Neuropharmacology (01.09.2007)
Published in Neuropharmacology (01.09.2007)
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Journal Article
Modeling the 3D structure of GPCRs from sequence
Shacham, Sharon, Topf, Maya, Avisar, Noa, Glaser, Fabian, Marantz, Yael, Bar-Haim, Shay, Noiman, Silvia, Naor, Zvi, Becker, Oren M.
Published in Medicinal research reviews (01.09.2001)
Published in Medicinal research reviews (01.09.2001)
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Journal Article
Conference Proceeding
VRX-03011, a novel 5-HT 4 agonist, enhances memory and hippocampal acetylcholine efflux
Mohler, Eric G., Shacham, Sharon, Noiman, Silvia, Lezoualc'h, Frank, Robert, Sylvain, Gastineau, Monique, Rutkowski, Joseph, Marantz, Yael, Dumuis, Aline, Bockaert, Joel, Gold, Paul E., Ragozzino, Michael E.
Published in Neuropharmacology (2007)
Published in Neuropharmacology (2007)
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Journal Article
An Integrated in Silico 3D Model-Driven Discovery of a Novel, Potent, and Selective Amidosulfonamide 5-HT 1A Agonist (PRX-00023) for the Treatment of Anxiety and Depression
Becker, Oren M., Dhanoa, Dale S., Marantz, Yael, Chen, Dongli, Shacham, Sharon, Cheruku, Srinivasa, Heifetz, Alexander, Mohanty, Pradyumna, Fichman, Merav, Sharadendu, Anurag, Nudelman, Raphael, Kauffman, Michael, Noiman, Silvia
Published in Journal of medicinal chemistry (01.06.2006)
Published in Journal of medicinal chemistry (01.06.2006)
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Journal Article
O3-05-03: PRX-03140: a novel 5-HT4 partial agonist with a dual cholinergic/disease-modifying mechanism for the treatment of Alzheimer disease
Shacham, Sharon, Milgram, Bill, Araujo, Joseph, Ragazzino, Michael, Mohler, Eric, Marantz, Yael, Mercedes, Lobera, Noiman, Silvia
Published in Alzheimer's & dementia (01.07.2006)
Published in Alzheimer's & dementia (01.07.2006)
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Journal Article
The X Protein of Hepatitis B Virus Has a ribo/deoxy ATPase Activity
De-Medina, Tali, Haviv, Izhak, Noiman, Silvia, Shaul, Yosef
Published in Virology (New York, N.Y.) (01.07.1994)
Published in Virology (New York, N.Y.) (01.07.1994)
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Journal Article
Structural and functional characterization of rev-like transcripts of equine infectious anemia virus
Rosin-Arbesfeld, R, Rivlin, M, Noiman, S, Mashiah, P, Yaniv, A, Miki, T, Tronick, S.R, Gazit, A
Published in Journal of Virology (01.09.1993)
Published in Journal of Virology (01.09.1993)
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Journal Article
THIENOPYRIDINONE COMPOUNDS AND METHODS OF TREATMENT
BECKER, OREN, WU, LAURENCE, BAR-HAIM, SHAY, HEIFETZ, ALEXANDER, MOHANTY, PRADYUMNA, MARANTZ, YAEL, NOIMAN, SILVIA, CHEN, DONGLI, LOBERA, MERCEDES, SHACHAM, SHARON, DHANOA, DALE S, INBAL, BOAZ
Year of Publication 09.07.2013
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Year of Publication 09.07.2013
Patent
COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS
WU, LAURENCE, BAR-HAIM, SHAY, MOHANTY, PRADYUMNA, HEIFETZ, ALEXANDER, MARANTZ, YAEL, NOIMAN, SILVIA, BECKER, OREN M, CHEN, DONGLI, LOBERA, MERCEDES, SHACHAM, SHARON, DHANOA, DALE S, INBAL, BOAZ
Year of Publication 12.08.2014
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Year of Publication 12.08.2014
Patent
SUBSTITUTED ARYLAMINE COMPOUNDS AND THEIR USE AS 5-HT6 MODULATORS
SHARADENDU, ANURAG, WU, LAURENCE, CHERUKU, SRINIVASA RAO, SENDEROWITZ, HANOCH, SAHA, ASHIS, MARANTZ, YAEL, NOIMAN, SILVIA, LOBERA, MERCEDES, DHANOA, DALE S, BECKER, OREN, YU, XIANG Y, ORBACH, PINI, MELENDEZ, ROSA E, SHACHAM, SHARON, FICHMAN, MERAV
Year of Publication 15.07.2014
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Year of Publication 15.07.2014
Patent