Preclinical Development and First-in-Human Study of KA2507, a Selective and Potent Inhibitor of Histone Deacetylase 6, for Patients with Refractory Solid Tumors
Tsimberidou, Apostolia M, Beer, Philip A, Cartwright, Carrie A, Haymaker, Cara, Vo, Henry H, Kiany, Simin, Cecil, Alexander R L, Dow, James, Haque, Kemal, Silva, Franck A, Coe, Lucy, Berryman, Helen, Bone, Elisabeth A, Nogueras-Gonzalez, Graciela M, Vining, David, McElwaine-Johnn, Hilary, Wistuba, Ignacio I
Published in Clinical cancer research (01.07.2021)
Published in Clinical cancer research (01.07.2021)
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Game on, science - how video game technology may help biologists tackle visualization challenges
Lv, Zhihan, Tek, Alex, Da Silva, Franck, Empereur-mot, Charly, Chavent, Matthieu, Baaden, Marc
Published in PloS one (06.03.2013)
Published in PloS one (06.03.2013)
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Ranking docking poses by graph matching of protein–ligand interactions: lessons learned from the D3R Grand Challenge 2
da Silva Figueiredo Celestino Gomes, Priscila, Da Silva, Franck, Bret, Guillaume, Rognan, Didier
Published in Journal of computer-aided molecular design (01.01.2018)
Published in Journal of computer-aided molecular design (01.01.2018)
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Preclinical and phase I studies of KA2237, a selective and potent inhibitor of PI3K β/δ in relapsed refractory B cell lymphoma
Nastoupil, Loretta J., Neelapu, Sattva S., Davis, Richard Eric, Samaniego, Felipe, Fowler, Nathan H., Westin, Jason, Lee, Hun Ju, Wang, Michael, Hagemeister, Fredrick, Cecil, Alexander R. L., Dow, James, Haque, Kemal, Silva, Franck A., Whale, Andrew, Lensun, Letitia, Bone, Elisabeth A., McElwaine-Johnn, Hilary, Beer, Philip A.
Published in Leukemia & lymphoma (06.12.2021)
Published in Leukemia & lymphoma (06.12.2021)
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Improving Prediction of Metabolic Clearance Using Quantitative Extrapolation of Results Obtained From Human Hepatic Micropatterned Cocultures Model and by Considering the Impact of Albumin Binding
Da-silva, Franck, Boulenc, Xavier, Vermet, Hélène, Compigne, Pauline, Gerbal-Chaloin, Sabine, Daujat-Chavanieu, Martine, Klieber, Sylvie, Poulin, Patrick
Published in Journal of pharmaceutical sciences (01.07.2018)
Published in Journal of pharmaceutical sciences (01.07.2018)
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Pd(II)-Catalyzed Cascade Wacker−Heck Reaction: Chemoselective Coupling of Two Electron-Deficient Reactants
Silva, Franck, Reiter, Maud, Mills-Webb, Rebecca, Sawicki, Marcin, Klär, Daniel, Bensel, Nicolas, Wagner, Alain, Gouverneur, Véronique
Published in Journal of organic chemistry (27.10.2006)
Published in Journal of organic chemistry (27.10.2006)
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Modeling complex biological systems: From solution chemistry to membranes and channels
Laurent, Benoist, Murail, Samuel, Da Silva, Franck, Corringer, Pierre-Jean, Baaden, Marc
Published in Pure and Applied Chemistry (01.01.2013)
Published in Pure and Applied Chemistry (01.01.2013)
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Conference Proceeding
Unsupervised Classification of G‑Protein Coupled Receptors and Their Conformational States Using IChem Intramolecular Interaction Patterns
Koensgen, Florian, Da Silva, Franck, Rognan, Didier, Kellenberger, Esther
Published in Journal of chemical information and modeling (23.09.2019)
Published in Journal of chemical information and modeling (23.09.2019)
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Gold(I)-Catalyzed Alkoxyhalogenation of β-Hydroxy-α,α-Difluoroynones
Schuler, Marie, Silva, Franck, Bobbio, Carla, Tessier, Arnaud, Gouverneur, Véronique
Published in Angewandte Chemie (International ed.) (29.09.2008)
Published in Angewandte Chemie (International ed.) (29.09.2008)
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Results of a First in Human, Dose Ascending, Phase I Study Examining the Safety and Tolerability of KA2237, an Oral PI3K p110β/δ Inhibitor in Patients with Relapsed/Refractory (R/R) B-Cell Lymphoma
Nastoupil, Loretta J., Neelapu, Sattva S, Davis, Eric, Samaniego, Felipe, Fowler, Nathan H, Westin, Jason R., Lee, Hun Ju, Wang, Michael, Hagemeister, Fredrick B., Beer, Philip, Cecil, Alexander R.L., Dow, James, McHale, Duncan, Silva, Franck, Ward, Penny, Yavari, Arash, Shuttleworth, Stephen Joseph
Published in Blood (13.11.2019)
Published in Blood (13.11.2019)
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Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling
Briolotti, Philippe, Chaloin, Laurent, Balaguer, Patrick, Da Silva, Franck, Tománková, Veronika, Pascussi, Jean-Marc, Duret, Cédric, Fabre, Jean-Michel, Ramos, Jeanne, Klieber, Sylvie, Maurel, Patrick, Daujat-Chavanieu, Martine, Gerbal-Chaloin, Sabine
Published in Toxicological Sciences (01.11.2015)
Published in Toxicological Sciences (01.11.2015)
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