Adaptive Therapy
GATENBY, Robert A, SILVA, Ariosto S, GILLIES, Robert J, FRIEDEN, B. Roy
Published in Cancer research (Chicago, Ill.) (01.06.2009)
Published in Cancer research (Chicago, Ill.) (01.06.2009)
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Classifying the evolutionary and ecological features of neoplasms
Maley, Carlo C., Aktipis, Athena, Graham, Trevor A., Sottoriva, Andrea, Boddy, Amy M., Janiszewska, Michalina, Silva, Ariosto S., Gerlinger, Marco, Yuan, Yinyin, Pienta, Kenneth J., Anderson, Karen S., Gatenby, Robert, Swanton, Charles, Posada, David, Wu, Chung-I, Schiffman, Joshua D., Hwang, E. Shelley, Polyak, Kornelia, Anderson, Alexander R. A., Brown, Joel S., Greaves, Mel, Shibata, Darryl
Published in Nature reviews. Cancer (01.10.2017)
Published in Nature reviews. Cancer (01.10.2017)
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Evolutionary approaches to prolong progression-free survival in breast cancer
Silva, Ariosto S, Kam, Yoonseok, Khin, Zayar P, Minton, Susan E, Gillies, Robert J, Gatenby, Robert A
Published in Cancer research (Chicago, Ill.) (15.12.2012)
Published in Cancer research (Chicago, Ill.) (15.12.2012)
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BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models
Zhao, Xiaohong, Ren, Yuan, Lawlor, Matthew, Shah, Bijal D., Park, Paul M.C., Lwin, Tint, Wang, Xuefeng, Liu, Kenian, Wang, Michelle, Gao, Jing, Li, Tao, Xu, Mousheng, Silva, Ariosto S., Lee, Kaplan, Zhang, Tinghu, Koomen, John M., Jiang, Huijuan, Sudalagunta, Praneeth R., Meads, Mark B., Cheng, Fengdong, Bi, Chengfeng, Fu, Kai, Fan, Huitao, Dalton, William S., Moscinski, Lynn C., Shain, Kenneth H., Sotomayor, Eduardo M., Wang, Gang Greg, Gray, Nathanael S., Cleveland, John L., Qi, Jun, Tao, Jianguo
Published in Cancer cell (13.05.2019)
Published in Cancer cell (13.05.2019)
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Whole-Exome sequencing analysis identified TMSB10/TRABD2A locus to be associated with carfilzomib-related cardiotoxicity among patients with multiple myeloma
Tantawy, Marwa, Yang, Guang, Algubelli, Raghunandan Reddy, DeAvila, Gabriel, Rubinstein, Samuel M, Cornell, Robert F, Fradley, Michael G, Siegel, Erin M, Hampton, Oliver A, Silva, Ariosto S, Lenihan, Daniel, Shain, Kenneth H, Baz, Rachid C, Gong, Yan
Published in Frontiers in cardiovascular medicine (20.06.2023)
Published in Frontiers in cardiovascular medicine (20.06.2023)
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Therapeutic Targeting of Protein Disulfide Isomerase PDIA1 in Multiple Myeloma
Hasipek, Metis, Grabowski, Dale, Guan, Yihong, Alugubelli, Raghunandan Reddy, Tiwari, Anand D., Gu, Xiaorong, DeAvila, Gabriel A., Silva, Ariosto S., Meads, Mark B., Parker, Yvonne, Lindner, Daniel J., Saunthararajah, Yogen, Shain, Kenneth H., Maciejewski, Jaroslaw P., Reu, Frederic J., Phillips, James G., Jha, Babal K.
Published in Cancers (28.05.2021)
Published in Cancers (28.05.2021)
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A pharmacodynamic model of clinical synergy in multiple myeloma
Sudalagunta, Praneeth, Silva, Maria C., Canevarolo, Rafael R., Alugubelli, Raghunandan Reddy, DeAvila, Gabriel, Tungesvik, Alexandre, Perez, Lia, Gatenby, Robert, Gillies, Robert, Baz, Rachid, Meads, Mark B., Shain, Kenneth H., Silva, Ariosto S.
Published in EBioMedicine (01.04.2020)
Published in EBioMedicine (01.04.2020)
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Plasma cell dependence on histone/protein deacetylase 11 reveals a therapeutic target in multiple myeloma
Mostofa, Agm, Distler, Allison, Meads, Mark B, Sahakian, Eva, Powers, John J, Achille, Alexandra, Noyes, David, Wright, Gabriela, Fang, Bin, Izumi, Victoria, Koomen, John, Rampakrishnan, Rupal, Nguyen, Tuan P, De Avila, Gabriel, Silva, Ariosto S, Sudalagunta, Praneeth, Canevarolo, Rafael Renatino, Siqueira Silva, Maria D Coelho, Alugubelli, Raghunandan Reddy, Dai, Hongyue A, Kulkarni, Amit, Dalton, William S, Hampton, Oliver A, Welsh, Eric A, Teer, Jamie K, Tungesvik, Alexandre, Wright, Kenneth L, Pinilla-Ibarz, Javier, Sotomayor, Eduardo M, Shain, Kenneth H, Brayer, Jason
Published in JCI insight (22.12.2021)
Published in JCI insight (22.12.2021)
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Replicative Instability Drives Cancer Progression
Morris, Benjamin B, Smith, Jason P, Zhang, Qi, Jiang, Zhijie, Hampton, Oliver A, Churchman, Michelle L, Arnold, Susanne M, Owen, Dwight H, Gray, Jhanelle E, Dillon, Patrick M, Soliman, Hatem H, Stover, Daniel G, Colman, Howard, Chakravarti, Arnab, Shain, Kenneth H, Silva, Ariosto S, Villano, John L, Vogelbaum, Michael A, Borges, Virginia F, Akerley, Wallace L, Gentzler, Ryan D, Hall, Richard D, Matsen, Cindy B, Ulrich, C M, Post, Andrew R, Nix, David A, Singer, Eric A, Larner, James M, Stukenberg, Peter Todd, Jones, David R, Mayo, Marty W
Published in Biomolecules (Basel, Switzerland) (26.10.2022)
Published in Biomolecules (Basel, Switzerland) (26.10.2022)
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PLK1 stabilizes a MYC-dependent kinase network in aggressive B cell lymphomas
Ren, Yuan, Bi, Chengfeng, Zhao, Xiaohong, Lwin, Tint, Wang, Cheng, Yuan, Ji, Silva, Ariosto S, Shah, Bijal D, Fang, Bin, Li, Tao, Koomen, John M, Jiang, Huijuan, Chavez, Julio C, Pham, Lan V, Sudalagunta, Praneeth R, Wan, Lixin, Wang, Xuefeng, Dalton, William S, Moscinski, Lynn C, Shain, Kenneth H, Vose, Julie, Cleveland, John L, Sotomayor, Eduardo M, Fu, Kai, Tao, Jianguo
Published in The Journal of clinical investigation (01.12.2018)
Published in The Journal of clinical investigation (01.12.2018)
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Combined MEK1/2 and ATR inhibition promotes myeloma cell death through a STAT3-dependent mechanism in vitro and in vivo
Li, Lin, Hu, Xiaoyan, Nkwocha, Jewel, Kmieciak, Maciej, Meads, Mark B, Shain, Kenneth H, Alugubelli, Raghunandan R, Silva, Ariosto S, Mann, Hashim, Sudalagunta, Praneeth R, Canevarolo, Rafael R, Zhou, Liang, Grant, Steven
Published in British journal of haematology (08.10.2024)
Published in British journal of haematology (08.10.2024)
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The Functional Transcriptomic Landscape Informs Therapeutic Strategies in Multiple Myeloma
Sudalagunta, Praneeth Reddy, Canevarolo, Rafael R, Meads, Mark B, Silva, Maria, Zhao, Xiaohong, Cubitt, Christopher L, Sansil, Samer S, DeAvila, Gabriel, Alugubelli, Raghunandan Reddy, Bishop, Ryan T, Tungesvik, Alexandre, Zhang, Qi, Hampton, Oliver, Teer, Jamie K, Welsh, Eric A, Yoder, Sean J, Shah, Bijal D, Hazlehurst, Lori, Gatenby, Robert A, Van Domelen, Dane R, Chai, Yi, Wang, Feng, DeCastro, Andrew, Bloomer, Amanda M, Siegel, Erin M, Lynch, Conor C, Sullivan, Daniel M, Alsina, Melissa, Nishihori, Taiga, Brayer, Jason, Cleveland, John L, Dalton, William, Walker, Christopher J, Landesman, Yosef, Baz, Rachid, Silva, Ariosto S, Shain, Kenneth H
Published in Cancer research (Chicago, Ill.) (30.10.2024)
Published in Cancer research (Chicago, Ill.) (30.10.2024)
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CK1δ and CK1ε Signaling Sustains Mitochondrial Metabolism and Cell Survival in Multiple Myeloma
Burger, Karen L, Fernandez, Mario R, Meads, Mark B, Sudalagunta, Praneeth, Oliveira, Paula S, Renatino Canevarolo, Rafael, Alugubelli, Raghunandan Reddy, Tungsevik, Alexandre, De Avila, Gabe, Silva, Maria, Graeter, Allison I, Dai, Hongyue A, Vincelette, Nicole D, Prabhu, Antony, Magaletti, Dario, Yang, Chunying, Li, Weimin, Kulkarni, Amit, Hampton, Oliver, Koomen, John M, Roush, William R, Monastyrskyi, Andrii, Berglund, Anders E, Silva, Ariosto S, Cleveland, John L, Shain, Kenneth H
Published in Cancer research (Chicago, Ill.) (01.12.2023)
Published in Cancer research (Chicago, Ill.) (01.12.2023)
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CancerCellTracker: a brightfield time-lapse microscopy framework for cancer drug sensitivity estimation
Jiang, Qibing, Sudalagunta, Praneeth, Silva, Maria C, Canevarolo, Rafael R, Zhao, Xiaohong, Ahmed, Khandakar Tanvir, Alugubelli, Raghunandan Reddy, DeAvila, Gabriel, Tungesvik, Alexandre, Perez, Lia, Gatenby, Robert A, Gillies, Robert J, Baz, Rachid, Meads, Mark B, Shain, Kenneth H, Silva, Ariosto S, Zhang, Wei
Published in Bioinformatics (10.08.2022)
Published in Bioinformatics (10.08.2022)
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Metabolic Changes Are Associated with Melphalan Resistance in Multiple Myeloma
Koomen, David C, Meads, Mark B, Magaletti, Dario M, Guingab-Cagmat, Joy D, Oliveira, Paula S, Fang, Bin, Liu, Min, Welsh, Eric A, Meke, Laurel E, Jiang, Zhijie, Hampton, Oliver A, Tungesvik, Alexandre, De Avila, Gabriel, Alugubelli, Raghunandan Reddy, Nishihori, Taiga, Silva, Ariosto S, Eschrich, Steven A, Garrett, Timothy J, Koomen, John M, Shain, Kenneth H
Published in Journal of proteome research (04.06.2021)
Published in Journal of proteome research (04.06.2021)
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A Preclinical Assay for Chemosensitivity in Multiple Myeloma
KHIN, Zayar P, RIBEIRO, Maria L. C, JACOBSON, Timothy, HAZLEHURST, Lori, PEREZ, Lia, BAZ, Rachid, SHAIN, Kenneth, SILVA, Ariosto S
Published in Cancer research (Chicago, Ill.) (01.01.2014)
Published in Cancer research (Chicago, Ill.) (01.01.2014)
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Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma
Zhao, Xiaohong, Wang, Michelle Y., Jiang, Huijuan, Lwin, Tint, Park, Paul M., Gao, Jing, Meads, Mark B., Ren, Yuan, Li, Tao, Sun, Jiao, Fahmi, Naima Ahmed, Singh, Satishkumar, Sehgal, Lalit, Wang, Xuefeng, Silva, Ariosto S., Sotomayor, Eduardo M., Shain, Kenneth H., Cleveland, John L., Wang, Michael, Zhang, Wei, Qi, Jun, Shah, Bijal D., Tao, Jianguo
Published in Cell reports (Cambridge) (16.03.2021)
Published in Cell reports (Cambridge) (16.03.2021)
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Resistance to Ibrutinib in B Cell Malignancies: One Size Does Not Fit All
Shah, Bijal, Zhao, Xiaohong, Silva, Ariosto S, Shain, Kenneth H, Tao, Jianguo
Published in Trends in cancer (01.03.2018)
Published in Trends in cancer (01.03.2018)
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