A Nonpeptidyl Mimic of Superoxide Dismutase with Therapeutic Activity in Rats
Salvemini, Daniela, Wang, Zhi-Qiang, Zweier, Jay L., Samouilov, Alexandre, Macarthur, Heather, Misko, Thomas P., Currie, Mark G., Cuzzocrea, Salvatore, Sikorski, James A., Riley, Dennis P.
Published in Science (American Association for the Advancement of Science) (08.10.1999)
Published in Science (American Association for the Advancement of Science) (08.10.1999)
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Novel Biologically Active Nonpeptidic Inhibitors of MyristoylCoA:Protein N-Myristoyltransferase
Devadas, Balekudru, Freeman, Sandra K, McWherter, Charles A, Kishore, Nandini S, Lodge, Jennifer K, Jackson-Machelski, Emily, Gordon, Jeffrey I, Sikorski, James A
Published in Journal of medicinal chemistry (12.03.1998)
Published in Journal of medicinal chemistry (12.03.1998)
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Design and Synthesis of Novel Imidazole-Substituted Dipeptide Amides as Potent and Selective Inhibitors of Candida albicans MyristoylCoA:Protein N-Myristoyltransferase and Identification of Related Tripeptide Inhibitors with Mechanism-Based Antifungal Activity
Devadas, Balekudru, Freeman, Sandra K, Zupec, Mark E, Lu, Hwang-Fun, Nagarajan, Srinivasan R, Kishore, Nandini S, Lodge, Jennifer K, Kuneman, David W, McWherter, Charles A, Vinjamoori, Dutt V, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A
Published in Journal of medicinal chemistry (01.08.1997)
Published in Journal of medicinal chemistry (01.08.1997)
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Discovery of Chiral N,N-Disubstituted Trifluoro-3-amino-2-propanols as Potent Inhibitors of Cholesteryl Ester Transfer Protein
Durley, Richard C, Grapperhaus, Margaret L, Massa, Mark A, Mischke, Deborah A, Parnas, Barry L, Fobian, Yvette M, Rath, Nigam P, Honda, Dorothy D, Zeng, Ming, Connolly, Daniel T, Heuvelman, Deborah M, Witherbee, Bryan J, Glenn, Kevin C, Krul, Elaine S, Smith, Mark E, Sikorski, James A
Published in Journal of medicinal chemistry (30.11.2000)
Published in Journal of medicinal chemistry (30.11.2000)
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Stereospecific Inhibition of CETP by Chiral N,N-Disubstituted Trifluoro-3-amino-2-propanols
Connolly, Daniel T, Witherbee, Bryan J, Melton, Michele A, Durley, Richard C, Grapperhaus, Margaret L, McKinnis, Brad R, Vernier, William F, Babler, Maribeth A, Shieh, Jeng-Jong, Smith, Mark E, Sikorski, James A
Published in Biochemistry (Easton) (14.11.2000)
Published in Biochemistry (Easton) (14.11.2000)
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A tetrahedral intermediate in the EPSP synthase reaction observed by rapid quench kinetics
Anderson, Karen S, Sikorski, James A, Johnson, Kenneth A
Published in Biochemistry (Easton) (01.09.1988)
Published in Biochemistry (Easton) (01.09.1988)
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Design and Syntheses of Potent and Selective Dipeptide Inhibitors of Candida albicans Myristoyl-CoA:Protein N-Myristoyltransferase
Devadas, Balekudru, Zupec, Mark E, Freeman, Sandra K, Brown, David L, Nagarajan, Srinivasan, Sikorski, James A, McWherter, Charles A, Getman, Daniel P, Gordon, Jeffrey I
Published in Journal of medicinal chemistry (01.05.1995)
Published in Journal of medicinal chemistry (01.05.1995)
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Conformationally Constrained [p-(ω-Aminoalkyl)phenacetyl]-l-seryl-l-lysyl Dipeptide Amides as Potent Peptidomimetic Inhibitors of Candida albicans and Human Myristoyl-CoA:Protein N-Myristoyl Transferase
Nagarajan, Srinivasan R, Devadas, Balekudru, Zupec, Mark E, Freeman, Sandra K, Brown, David L, Lu, Hwang-Fun, Mehta, Pramod P, Kishore, Nandini S, McWherter, Charles A, Getman, Daniel P, Gordon, Jeffrey I, Sikorski, James A
Published in Journal of medicinal chemistry (09.05.1997)
Published in Journal of medicinal chemistry (09.05.1997)
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Identification of the reactive cysteines of Escherichia coli 5-enolpyruvylshikimate-3-phosphate synthase and their nonessentiality for enzymatic catalysis
Padgette, S R, Huynh, Q K, Aykent, S, Sammons, R D, Sikorski, J A, Kishore, G M
Published in The Journal of biological chemistry (05.02.1988)
Published in The Journal of biological chemistry (05.02.1988)
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Synthesis and Cytotoxicity of 2,4-Disubstituted and 2,3,4-Trisubstituted Brominated Pyrroles in Murine and Human Cultured Tumor Cells
Gupton, John T., Burham, Bruce S., Krumpe, Keith, Du, Karen, Sikorski, James A., Warren, Amy E., Barnes, Cheryl R., Hall, Iris. H.
Published in Archiv der Pharmazie (Weinheim) (01.01.2000)
Published in Archiv der Pharmazie (Weinheim) (01.01.2000)
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EPSP synthase: binding studies using isothermal titration microcalorimetry and equilibrium dialysis and their implications for ligand recognition and kinetic mechanism
Ream, Joel E, Yuen, Henry K, Frazier, Ronald B, Sikorski, James A
Published in Biochemistry (Easton) (23.06.1992)
Published in Biochemistry (Easton) (23.06.1992)
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Novel heteroaryl replacements of aromatic 3-tetrafluoroethoxy substituents in trifluoro-3-(tertiaryamino)-2-propanols as potent inhibitors of cholesteryl ester transfer protein
Massa, Mark A., Spangler, Dale P., Durley, Richard C., Hickory, Brian S., Connolly, Daniel T., Witherbee, Bryan J., Smith, Mark E., Sikorski, James A.
Published in Bioorganic & medicinal chemistry letters (09.07.2001)
Published in Bioorganic & medicinal chemistry letters (09.07.2001)
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Soybean pod set enhancement with synthetic cytokinin analogs
Dyer, D.J, Carlson, D.R, Cotterman, C.D, Sikorski, J.A, Ditson, S.L
Published in Plant physiology (Bethesda) (01.06.1987)
Published in Plant physiology (Bethesda) (01.06.1987)
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Genetic and biochemical studies establish that the fungicidal effect of a fully depeptidized inhibitor of Cryptococcus neoformans myristoyl-CoA:protein N-myristoyltransferase (Nmt) is Nmt-dependent
Lodge, J K, Jackson-Machelski, E, Higgins, M, McWherter, C A, Sikorski, J A, Devadas, B, Gordon, J I
Published in The Journal of biological chemistry (15.05.1998)
Published in The Journal of biological chemistry (15.05.1998)
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Differential scanning calorimetric study of 5-enolpyruvoyl shikimate-3-phosphate synthase and its complexes with shikimate-3-phosphate and glyphosate: Irreversible thermal transitions
Merabet, Eddine K., Walker, Mark C., Yuen, Henry K., Sikorski, James A.
Published in Biochimica et biophysica acta (13.02.1993)
Published in Biochimica et biophysica acta (13.02.1993)
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Titration Calorimetric Analysis of AcylCoA Recognition by MyristoylCoA:Protein N-Myristoyltransferase
Bhatnagar, Rajiv S, Schall, Otto F, Jackson-Machelski, Emily, Sikorski, James A, Devadas, Balekudru, Gokel, George W, Gordon, Jeffrey I
Published in Biochemistry (Easton) (03.06.1997)
Published in Biochemistry (Easton) (03.06.1997)
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Structure and topological symmetry of the glyphosate target 5-enol-pyruvylshikimate-3-phosphate synthase: A distinctive protein fold
Stallings, W.C. (Monsanto Company, St. Louis, MO), Abdel-Meguid, S.S, Lim, L.W, Shieh, H.S, Dayringer, H.E, Leimgruber, N.K, Stegeman, R.A, Anderson, K.S, Sikorski, J.A, Padgette, S.R, Kishore, G.M
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.1991)
Published in Proceedings of the National Academy of Sciences - PNAS (01.06.1991)
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