Phase I/II study of weekly PM00104 (Zalypsis®) in patients with relapsed/refractory multiple myeloma
Ocio, Enrique M., Oriol, Albert, Bladé, Joan, Teruel, Ana I., Martín, Jesus, Rubia, Javier, Gutiérrez, Norma C., Rodríguez Díaz‐Pavón, José, Martínez González, Sara, Coronado, Cinthya, Fernández‐García, Eva M., Siguero Gómez, Mariano, Fernández‐Teruel, Carlos, San Miguel, Jesus
Published in British journal of haematology (01.02.2016)
Published in British journal of haematology (01.02.2016)
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Journal Article
Phase I study of lurbinectedin in combination with weekly paclitaxel with or without bevacizumab in patients with advanced solid tumors
Calvo, Emiliano, Sessa, Cristiana, Harada, Guilherme, de Miguel, Maria, Kahatt, Carmen, Luepke-Estefan, Xarles Erik, Siguero, Mariano, Fernandez-Teruel, Carlos, Cullell-Young, Martin, Stathis, Anastasios, Drilon, Alexander
Published in Investigational new drugs (01.12.2022)
Published in Investigational new drugs (01.12.2022)
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Journal Article
Antitumor Activity of Lurbinectedin, a Selective Inhibitor of Oncogene Transcription, in Patients with Relapsed Ewing Sarcoma: Results of a Basket Phase II Study
Subbiah, Vivek, Braña, Irene, Longhi, Alessandra, Boni, Valentina, Delord, Jean-Pierre, Awada, Ahmad, Boudou-Rouquette, Pascaline, Sarantopoulos, John, Shapiro, Geoffrey I, Elias, Anthony, Ratan, Ravin, Fernandez, Cristian, Kahatt, Carmen, Cullell-Young, Martin, Siguero, Mariano, Zeaiter, Ali, Chawla, Sant P
Published in Clinical cancer research (01.07.2022)
Published in Clinical cancer research (01.07.2022)
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Journal Article
Lurbinectedin in patients with pretreated neuroendocrine tumours: Results from a phase II basket study
Longo-Muñoz, Federico, Castellano, Daniel, Alexandre, Jerome, Chawla, Sant P., Fernández, Cristian, Kahatt, Carmen, Alfaro, Vicente, Siguero, Mariano, Zeaiter, Ali, Moreno, Victor, Sanz-García, Enrique, Awada, Ahmad, Santaballa, Ana, Subbiah, Vivek
Published in European journal of cancer (1990) (01.09.2022)
Published in European journal of cancer (1990) (01.09.2022)
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Journal Article
Safety analysis of lurbinectedin versus topotecan in elderly patients
Subbiah, Vivek, Lorusso, Domenica, Trigo Perez, Jose Manuel Manuel, Leary, Alexandra, Moreno, Victor, Kristeleit, Rebecca, Vergote, Ignace, Lopez-Vilariño, Jose Antonio, Fernandez, Cristian Marcelo, Siguero, Mariano, Kahatt, Carmen Maria, Zeaiter, Ali Hassan, Boni, Valentina, Navarro, Alejandro, Gutierrez Calderon, Vanesa, Pardo, Beatriz, Berton, Dominique, Scambia, Giovanni
Published in Journal of clinical oncology (01.06.2023)
Published in Journal of clinical oncology (01.06.2023)
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Journal Article
First-In-Human Phase I Study of Lurbinectedin (PM01183) in Patients with Advanced Solid Tumors
ELEZ, María Elena, TABERNERO, Josep, SZYLDERGEMAJN, Sergio, RATAIN, Mark J, GEARY, David, MACARULLA, Teresa, KANG, S. Peter, KAHATT, Carmen, PITA, Arturo Soto-Matos, TERUEL, Carlos Fernandez, SIGUERO, Mariano, CULLELL-YOUNG, Martin
Published in Clinical cancer research (15.04.2014)
Published in Clinical cancer research (15.04.2014)
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Journal Article
Lurbinectedin in patients with pretreated endometrial cancer: results from a phase 2 basket clinical trial and exploratory translational study
Kristeleit, Rebecca, Leary, Alexandra, Delord, Jean Pierre, Moreno, Victor, Oaknin, Ana, Castellano, Daniel, Shappiro, Geoffrey I., Fernández, Cristian, Kahatt, Carmen, Alfaro, Vicente, Siguero, Mariano, Rueda, Daniel, Zeaiter, Ali, Awada, Ahmad, Santaballa, Ana, Zaman, Khalil, Sehouli, Jalid, Subbiah, Vivek
Published in Investigational new drugs (01.10.2023)
Published in Investigational new drugs (01.10.2023)
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Journal Article
Lurbinectedin in patients with pretreated BRCA 1/2-associated metastatic breast cancer: Results from a phase II basket study
Boni, Valentina, Pistilli, Barbara, Brana, Irene, Shapiro, Geoffrey, Trigo Perez, Jose Manuel Manuel, Moreno, Victor, Castellano, Daniel E., Fernandez, Cristian Marcelo, Kahatt, Carmen Maria, Alfaro, Vicente, Siguero, Mariano, Zeaiter, Ali Hassan, Longo, Federico, Zaman, Khalil, Antón Torres, Antonio, Paredes Lario, Alfredo, Huidobro Vence, Gerardo, Subbiah, Vivek
Published in Journal of clinical oncology (01.06.2022)
Published in Journal of clinical oncology (01.06.2022)
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Journal Article
Antitumor activity of lurbinectedin in second-line small cell lung cancer patients who are candidates for re-challenge with the first-line treatment
Subbiah, Vivek, Paz-Ares, Luis, Besse, Benjamin, Moreno, Victor, Peters, Solange, Sala, María Angeles, López-Vilariño, José Antonio, Fernández, Cristian, Kahatt, Carmen, Alfaro, Vicente, Siguero, Mariano, Zeaiter, Ali, Zaman, Khalil, López, Rafael, Ponce, Santiago, Boni, Valentina, Arrondeau, Jennifer, Delord, Jean-Pierre, Martínez, Maite, Wannesson, Luciano, Antón, Antonio, Valdivia, Javier, Awada, Ahmad, Kristeleit, Rebecca, Olmedo, Maria Eugenia, Rubio, María Jesús, Sarantopoulos, John, Chawla, Sant P., Mosquera-Martinez, Joaquín, D’ Arcangelo, Manolo, Santoro, Armando, Villalobos, Victor M., Sands, Jacob, Trigo, José
Published in Lung cancer (Amsterdam, Netherlands) (01.12.2020)
Published in Lung cancer (Amsterdam, Netherlands) (01.12.2020)
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Journal Article
Doxorubicin plus lurbinectedin in patients with advanced endometrial cancer: results from an expanded phase I study
Kristeleit, Rebecca, Moreno, Victor, Boni, Valentina, Guerra, Eva M, Kahatt, Carmen, Romero, Ignacio, Calvo, Emiliano, Basté, Neus, López-Vilariño, José A, Siguero, Mariano, Alfaro, Vicente, Zeaiter, Ali, Forster, Martin
Published in International journal of gynecological cancer (01.11.2021)
Published in International journal of gynecological cancer (01.11.2021)
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Journal Article
Lurbinectedin (LUR) in combination with Irinotecan (IRI) in patients (pts) with advanced solid tumors: Updated results from a phase Ib-II trial
Ponce Aix, Santiago, Cote, Gregory Michael, Falcon Gonzalez, Alejandro, Sepulveda, Juan Manuel, Jimenez Aguilar, Elizabeth, Sanchez-Simon, Inmaculada, Flor, Maria José, Nuñez, Rafael, Gonzalez, Eva Maria, Insa, Monica, Siguero, Mariano, Cullell-Young, Martin, Kahatt, Carmen Maria, Zeaiter, Ali Hassan, Paz-Ares, Luis G.
Published in Journal of clinical oncology (20.05.2020)
Published in Journal of clinical oncology (20.05.2020)
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Journal Article
Phase I clinical and pharmacokinetic study of PM01183 (a tetrahydroisoquinoline, Lurbinectedin) in combination with gemcitabine in patients with advanced solid tumors
Paz-Ares, Luis, Forster, Martin, Boni, Valentina, Szyldergemajn, Sergio, Corral, Jesús, Turnbull, Samantha, Cubillo, Antonio, Teruel, Carlos Fernandez, Calderero, Iker López, Siguero, Mariano, Bohan, Patrick, Calvo, Emiliano
Published in Investigational new drugs (01.04.2017)
Published in Investigational new drugs (01.04.2017)
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Journal Article
Anti-tumor activity of PM1183 (lurbinectedin) in combination with capecitabine in metastatic breast cancer patients: Results from a phase I trial
Awada, Ahmad, Aftimos, Philippe Georges, Calvo, Emiliano, Boni, Valentina, Moreno, Victor, Doger, Bernard, Luepke, Xarles Erik, Zaragoza, Katrin, Siguero, Mariano, Kahatt, Carmen Maria, Soto-Matos, Arturo, Sauri, Tamara, Tabernero, Josep
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Efficacy and safety of lurbinectedin (PM1183) in Ewing sarcoma: Final results from a phase 2 study
Subbiah, Vivek, Sankhala, Kamalesh Kumar, Ratan, Ravin, Sanz Garcia, Enrique, Boni, Valentina, Gil, Thierry, Villalobos, Victor Manuel, Chawla, Sant P, Lardelli, Pilar, Siguero, Mariano, Kahatt, Carmen Maria, Soto-Matos, Arturo, Ferrari, Stefano
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Efficacy and safety profile of lurbinectedin in second-line SCLC patients: Results from a phase II single-agent trial
Paz-Ares, Luis G., Trigo Perez, Jose Manuel, Besse, Benjamin, Moreno, Victor, Lopez, Rafael, Sala, Maria Angeles, Ponce Aix, Santiago, Fernandez, Cristian Marcelo, Siguero, Mariano, Kahatt, Carmen Maria, Zeaiter, Ali Hassan, Zaman, Khalil, Boni, Valentina, Arrondeau, Jennifer, Martinez Aguillo, Maite, Delord, Jean-Pierre, Awada, Ahmad, Kristeleit, Rebecca Sophie, Olmedo Garcia, Maria Eugenia, Subbiah, Vivek
Published in Journal of clinical oncology (20.05.2019)
Published in Journal of clinical oncology (20.05.2019)
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Journal Article
Safety and Tolerability of Lurbinectedin (PM01183) in Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome
Chien, Kelly S., Benton, Christopher B., Tefferi, Ayalew, Rodríguez, José, Ravandi, Farhad, Daver, Naval G., Jabbour, Elias J., Jain, Nitin, Alvarado, Yesid, Kwari, Monica, Pierce, Sherry A., Maiti, Abhishek, Hornbaker, Marisa J, Almeida Santos, Margarida, Martinez, Sara, Siguero, Mariano, Zblewski, Darci, Al-Kali, Aref, Hogan, William J., Kantarjian, Hagop M., Pardanani, Animesh, Garcia-Manero, Guillermo
Published in Blood (29.11.2018)
Published in Blood (29.11.2018)
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Journal Article
Efficacy and safety of lurbinectedin (PM1183) in small cell lung cancer (SCLC): Results from a phase 2 study
Trigo Perez, Jose Manuel, Leary, Alexandra, Besse, Benjamin, Castellano, Daniel E., Ponce Aix, Santiago, ARRONDEAU, Jennifer, Moreno, Victor, Doger, Bernard, Lopez, Rafael, Awada, Ahmad, Jungels, Christiane, Forster, Martin David, Boni, Valentina, Lardelli, Pilar, Siguero, Mariano, Kahatt, Carmen Maria, Soto-Matos, Arturo, Kristeleit, Rebecca Sophie
Published in Journal of clinical oncology (20.05.2018)
Published in Journal of clinical oncology (20.05.2018)
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Journal Article
Phase I study of lurbinectedin (PM11083) in patients with advanced AML and MDS
Benton, Christopher Brent, Rodriguez Diaz -Pavon, Jose, Maiti, Abhishek, Daver, Naval Guastad, Ravandi, Farhad, Jain, Nitin, Alvarado, Yesid, Jabbour, Elias, Pierce, Sherry, Kwari, Monica, Santos, Margarida A, Martinez, Sara, Siguero, Mariano, Tefferi, Ayalew, Cortes, Jorge E., Kantarjian, Hagop M., Pardanani, Animesh Dev, Garcia-Manero, Guillermo
Published in Journal of clinical oncology (20.05.2017)
Published in Journal of clinical oncology (20.05.2017)
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Journal Article
Safety and tolerability of lurbinectedin (PM01183) in patients with acute myeloid leukemia and myelodysplastic syndrome
Benton, Christopher B., Chien, Kelly S., Tefferi, Ayalew, Rodriguez, Jose, Ravandi, Farhad, Daver, Naval, Jabbour, Elias, Jain, Nitin, Alvarado, Yesid, Kwari, Monica, Pierce, Sherry, Maiti, Abhishek, Hornbaker, Marisa, Santos, Margarida A., Martinez, Sara, Siguero, Mariano, Zblewski, Darci, Al‐Kali, Aref, Hogan, William J., Kantarjian, Hagop, Pardanani, Animesh, Garcia‐Manero, Guillermo
Published in Hematological oncology (01.02.2019)
Published in Hematological oncology (01.02.2019)
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Journal Article
A Phase II multicenter, open-label, clinical and pharmokinetic trial of PM00104 in patients with advanced Ewing Family of Tumors
Jones, Robin L., Ferrari, Stefano, Blay, Jean Yves, Navid, Fariba, Lardelli, Pilar, Alfaro, Vicente, Siguero, Mariano, Soman, Neelesh, Chawla, Sant P.
Published in Investigational new drugs (01.02.2014)
Published in Investigational new drugs (01.02.2014)
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Journal Article