Omega-carboxypyridyl substituted ureas as Raf kinase inhibitors: SAR of the amide substituent
Khire, Uday R., Bankston, Donald, Barbosa, James, Brittelli, David R., Caringal, Yolanda, Carlson, Robert, Dumas, Jacques, Gane, Todd, Heald, Sarah L., Hibner, Barbara, Johnson, Jeffrey S., Katz, Michael E., Kennure, Nancy, Kingery-Wood, Jill, Lee, Wendy, Liu, Xiao-Gao, Lowinger, Timothy B., McAlexander, Ian, Monahan, Mary-Katherine, Natero, Reina, Renick, Joel, Riedl, Bernd, Rong, Hong, Sibley, Robert N., Smith, Roger A., Wolanin, Donald
Published in Bioorganic & medicinal chemistry letters (09.02.2004)
Published in Bioorganic & medicinal chemistry letters (09.02.2004)
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Synthesis and pharmacological characterization of a potent, orally active p38 kinase inhibitor
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Published in Bioorganic & medicinal chemistry letters (17.06.2002)
Published in Bioorganic & medicinal chemistry letters (17.06.2002)
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Journal Article
ω-CARBOXYARYL SUBSTITUTED DIPHENYL UREAS AS RAF KINASE INHIBITORS
KHIRE UDAY, MONAHAN MARY KATHERINE, RIEDL BERND, SMITH ROGER A, WOOD JILL E, RENICK JOEL, LOWINGER TIMOTHY B, DUMAS JACQUES, SIBLEY ROBERT N, SCOTT WILLIAM J, NATERO REINA
Year of Publication 10.06.2011
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Year of Publication 10.06.2011
Patent
Omega-carboxypyridyl substituted ureas as Raf kinase inhibitors
Khire, Uday R., Bankston, Donald, Barbosa, James, Brittelli, David R., Caringal, Yolanda, Carlson, Robert, Dumas, Jacques, Gane, Todd, Heald, Sarah L., Hibner, Barbara, Johnson, Jeffrey S., Katz, Michael E., Kennure, Nancy, Kingery-Wood, Jill, Lee, Wendy, Liu, Xiao-Gao, Lowinger, Timothy B., McAlexander, Ian, Monahan, Mary-Katherine, Natero, Reina, Renick, Joel, Riedl, Bernd, Rong, Hong, Sibley, Robert N., Smith, Roger A., Wolanin, Donald
Published in Bioorganic & medicinal chemistry letters (01.02.2004)
Published in Bioorganic & medicinal chemistry letters (01.02.2004)
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Journal Article
LU91280I
KHIRE Uday, RIEDL Bernd, DUMAS Jacques, MONAHAN Mary-Katherine, RENICK Joel, SMITH Roger, A, WOOD Jill, E, LOWINGER Timothy, B, SIBLEY Robert, N, SCOTT William, J, NATERO Reina
Year of Publication 02.01.2019
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Year of Publication 02.01.2019
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Omega-carboxaryl substituted diphenyl ureas as raf kinase inhibitors
Scott William J, Smith Roger A, Dumas Jacques, Natero Reina, Riedl Bernd, Khire Uday, Sibley Robert N, Monahan Mary-Katherine, Wood Jill E, Renick Joel, Lowinger Timothy B
Year of Publication 29.10.2018
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Year of Publication 29.10.2018
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Arylharnstoff-Verbindungen in Kombination mit anderen zytostatisch oder zytotoxisch wirksamen Stoffen zur Behandlungen menschlicher Krebserkrankungen
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Year of Publication 18.04.2024
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Year of Publication 18.04.2024
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Composto de difenil-uréias substituídas com ômega-carbóxi-arilas
Jill E. Wood, Robert N. Sibley, Timothy B. Lowinger, Dumas Jacques, Natero Reina, Riedl Bernd, Khire Uday, Monahan Mary-Katherine, William J. Scott, Renick Joel, Roger A. Smith
Year of Publication 14.09.2021
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Year of Publication 14.09.2021
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ARYL UREA COMPOUNDS IN COMBINATION WITH OTHER CYTOSTATIC OR CYTOTOXIC AGENTS FOR TREATING HUMAN CANCERS
CARTER, Christopher, A, HUMPHREY, Rachel, W, SCOTT, William, J, VINCENT, Patrick, W, RENICK, Joel, RIEDL, Bernd, MONAHAN, Mary-Katherine, HIBNER, Barbara, WOOD, Jill, E, LOWINGER, Timothy, B, ZHAI, Yifan, NATERO, Reina, SMITH, Roger, A, KHIRE, Uday, DUMAS, Jacques, GIBSON, Neil, TRAIL, Pamela, SIBLEY, Robert, N
Year of Publication 11.07.2018
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Year of Publication 11.07.2018
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piridinas e piridazinas substituídas com atividade de inibição de angiogênese bem como composições farmacêuticas compreendendo os mesmos
JULIE A. DIXON, Harold C. E. Kluender, Robert N. Sibley, Jacques P. Dumas, NING SU, Teddy Kite Joe, Dhanapalan Nagarathnam, Stephen James Boyer, WENDY LEE
Year of Publication 25.05.2021
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Year of Publication 25.05.2021
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difenil-uréias substituídas com w-carbóxi-arilas como inibidores de raf cinase
Jill E. Wood, Joel Renick, Uday Khire, Robert N. Sibley, Timothy B. Lowinger, Bernd Riedl, Reina Natero, Mary-Katherine Monahan, William J. Scott, Roger A. Smith, Jacques Dumas
Year of Publication 25.05.2021
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Year of Publication 25.05.2021
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Substituted pyridines and pyridazines with angiogenesis inhibiting activity and pharmaceutical compositions containing them
SU NING, KLUENDER HAROLD C. E, LEE WENDY, JOE TEDDY KITE, DUMAS JACQUES P, BOYER STEPHEN JAMES, NAGARATHNAM DHANAPALAN, SIBLEY ROBERT N, DIXON JULIE A
Year of Publication 28.10.2015
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Year of Publication 28.10.2015
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Difenil-uréias substituídas com w-carbóxi-arilas como inibidores de raf cinase
ROBERT N. SIBLEY, BERND RIEDL, JACQUES DUMAS, TIMOTHY B. LOWINGER, UDAY KHIRE, ROGER A. SMITH, JOEL RENICK, MARY-KATHERINE MONAHAN, REINA NATERO, WILLIAM J. SCOTT, JILL E. WOOD
Year of Publication 07.07.2015
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Year of Publication 07.07.2015
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Piridinas e piridazinas substituídas com atividade de inibição de angiogênese bem como composições farmacêuticas compreendendo os mesmos
ROBERT N. SIBLEY, JULIE A. DIXON, DHANAPALAN NAGARATHNAM, STEPHEN JAMES BOYER, TEDDY KITE JOE, NING SU, HAROLD C. E. KLUENDER, JACQUES P. DUMAS, WENDY LEE
Year of Publication 01.04.2014
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Year of Publication 01.04.2014
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Omega-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors
KHIRE UDAY, RIEDL BERND, SMITH ROGER A, WOOD JILL E, RENICK JOEL, LOWINGER TIMOTHY B, MONAHAN MARY-KATHERINE, DUMAS JACQUES, SIBLEY ROBERT N, SCOTT WILLIAM J, NATERO REINA
Year of Publication 31.10.2013
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Year of Publication 31.10.2013
Patent
OMEGA.-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS P38 KINASE INHIBITORS
DUMAS, JACQUES, SCOTT, WILLIAM J, LOWINGER, TIMOTHY B, KHIRE, UDAY, SMITH, ROGER A, WOOD, JILL E, NATERO, REINA, SIBLEY, ROBERT N, RENICK, JOEL, MONAHAN, MARY-KATHERINE, RIEDL, BERND
Year of Publication 08.10.2013
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Year of Publication 08.10.2013
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W-CARBOXY ARYL SUBSTITUTED DIPHENYL UREAS AS P38 KINASE INHIBITORS
DUMAS, JACQUES, SCOTT, WILLIAM J, LOWINGER, TIMOTHY B, KHIRE, UDAY, SMITH, ROGER A, WOOD, JILL E, NATERO, REINA, SIBLEY, ROBERT N, RENICK, JOEL, MONAHAN, MARY-KATHERINE, RIEDL, BERND
Year of Publication 01.06.2012
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Year of Publication 01.06.2012
Patent
OMEGA-CARBOXYARYLSUBSTITUIERTE-DIPHENYL- HARNSTOFFE ALS P38-KINASEHEMMER
DUMAS, JACQUES, SCOTT, WILLIAM J, LOWINGER, TIMOTHY B, KHIRE, UDAY, SMITH, ROGER A, WOOD, JILL E, NATERO, REINA, SIBLEY, ROBERT N, RENICK, JOEL, MONAHAN, MARY-KATHERINE, RIEDL, BERND
Year of Publication 15.05.2012
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Year of Publication 15.05.2012
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w-Carboxy aryl substituted diphenyl ureas as p38 kinase inhibitors
DUMAS, JACQUES, SCOTT, WILLIAM J, LOWINGER, TIMOTHY B, KHIRE, UDAY, SMITH, ROGER A, WOOD, JILL E, NATERO, REINA, SIBLEY, ROBERT N, RENICK, JOEL, MONAHAN, MARY-KATHERINE, RIEDL, BERND
Year of Publication 09.05.2012
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Year of Publication 09.05.2012
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composto de difenil-uréias substituídas com ?-carbóxi-arilas
Jill E. Wood, Joel Renick, Uday Khire, Robert N. Sibley, Timothy B. Lowinger, Bernd Riedl, Reina Natero, Mary-Katherine Monahan, William J. Scott, Roger A. Smith, Jacques Dumas
Year of Publication 14.02.2018
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Year of Publication 14.02.2018
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