Directed co-evolution of interacting protein–peptide pairs by compartmentalized two-hybrid replication (C2HR)
Siau, Jia Wei, Nonis, Samuel, Chee, Sharon, Koh, Li Quan, Ferrer, Fernando J, Brown, Christopher J, Ghadessy, Farid J
Published in Nucleic acids research (16.12.2020)
Published in Nucleic acids research (16.12.2020)
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Journal Article
Development and application of a transcriptional sensor for detection of heterologous acrylic acid production in E. coli
Raghavan, Sarada S, Chee, Sharon, Li, Juntao, Poschmann, Jeremie, Nagarajan, Niranjan, Jia Wei, Siau, Verma, Chandra S, Ghadessy, Farid J
Published in Microbial cell factories (19.08.2019)
Published in Microbial cell factories (19.08.2019)
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Journal Article
Simulations of mutant p53 DNA binding domains reveal a novel druggable pocket
Pradhan, Mohan R, Siau, Jia Wei, Kannan, Srinivasaraghavan, Nguyen, Minh N, Ouaray, Zohra, Kwoh, Chee Keong, Lane, David P, Ghadessy, Farid, Verma, Chandra S
Published in Nucleic acids research (28.02.2019)
Published in Nucleic acids research (28.02.2019)
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Journal Article
Thermostability enhancement of polyethylene terephthalate degrading PETase using self- and nonself-ligating protein scaffolding approaches
Sana, Barindra, Ding, Ke, Siau, Jia Wei, Pasula, Rupali Reddy, Chee, Sharon, Kharel, Sharad, Lena, Jean-Baptise Henri, Goh, Eunice, Rajamani, Lakshminarayanan, Lam, Yeng Ming, Lim, Sierin, Ghadessy, John F
Published in Biotechnology and bioengineering (01.11.2023)
Published in Biotechnology and bioengineering (01.11.2023)
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Journal Article
Expanding the DNA editing toolbox: Novel lambda integrase variants targeting microalgal and human genome sequences
Siau, Jia Wei, Siddiqui, Asim Azhar, Lau, Sze Yi, Kannan, Srinivasaraghavan, Peter, Sabrina, Zeng, Yingying, Verma, Chandra, Droge, Peter, Ghadessy, John F
Published in PloS one (13.02.2024)
Published in PloS one (13.02.2024)
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Journal Article
Rapid screening of protein–protein interaction inhibitors using the protease exclusion assay
Nirantar, Saurabh R., Li, Xiang, Siau, Jia Wei, Ghadessy, Farid J.
Published in Biosensors & bioelectronics (15.06.2014)
Published in Biosensors & bioelectronics (15.06.2014)
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Journal Article
Inhibition of nutlin-resistant HDM2 mutants by stapled peptides
Wei, Siau Jia, Joseph, Thomas, Chee, Sharon, Li, Ling, Yurlova, Larisa, Zolghadr, Kourosh, Brown, Christopher, Lane, David, Verma, Chandra, Ghadessy, Farid
Published in PloS one (20.11.2013)
Published in PloS one (20.11.2013)
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Journal Article
In vitro selection of mutant HDM2 resistant to Nutlin inhibition
Wei, Siau Jia, Joseph, Thomas, Sim, Adelene Y L, Yurlova, Larisa, Zolghadr, Kourosh, Lane, David, Verma, Chandra, Ghadessy, Farid
Published in PloS one (30.04.2013)
Published in PloS one (30.04.2013)
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Journal Article
Binding of Translationally Controlled Tumour Protein to the N-terminal domain of HDM2 is inhibited by nutlin-3
Funston, Garth, Goh, Walter, Wei, Siau Jia, Tng, Quah Soo, Brown, Christopher, Jiah Tong, Loh, Verma, Chandra, Lane, David, Ghadessy, Farid
Published in PloS one (13.08.2012)
Published in PloS one (13.08.2012)
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Journal Article
Avoiding drug resistance through extended drug target interfaces: a case for stapled peptides
Wei, Siau Jia, Chee, Sharon, Yurlova, Larisa, Lane, David, Verma, Chandra, Brown, Christopher, Ghadessy, Farid
Published in Oncotarget (31.05.2016)
Published in Oncotarget (31.05.2016)
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Journal Article
A "spindle and thread"mechanism unblocks p53 translation N-terminal disorder
Kaldmae, Margit, Vosselman, Thibault, Zhong, Xueying, Lama, Dilraj, Chen, Gefei, Saluri, Mihkel, Kronqvist, Nina, Siau, Jia Wei, Ng, Aik Seng, Ghadessy, Farid J., Sabatier, Pierre, Vojtesek, Borivoj, Sarr, Medoune, Sahin, Cagla, Österlund, Nicklas, Ilag, Leopold L., Vaananen, Venla A., Sedimbi, Saikiran, Arsenian-Henriksson, Marie, Zubarev, Roman A., Nilsson, Lennart, Koeck, Philip J. B., Rising, Anna, Abelein, Axel, Fritz, Nicolas, Johansson, Jan, Lane, David P., Landreh, Michael
Published in Structure (London) (2022)
Published in Structure (London) (2022)
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Journal Article
The p53-Mdm2 interaction and the E3 ligase activity of Mdm2/Mdm4 are conserved from lampreys to humans
Coffill, Cynthia R, Lee, Alison P, Siau, Jia Wei, Chee, Sharon M, Joseph, Thomas L, Tan, Yaw Sing, Madhumalar, Arumugam, Tay, Boon-Hui, Brenner, Sydney, Verma, Chandra S, Ghadessy, Farid J, Venkatesh, Byrappa, Lane, David P
Published in Genes & development (01.02.2016)
Published in Genes & development (01.02.2016)
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Journal Article
A “spindle and thread” mechanism unblocks p53 translation by modulating N-terminal disorder
Kaldmäe, Margit, Vosselman, Thibault, Zhong, Xueying, Lama, Dilraj, Chen, Gefei, Saluri, Mihkel, Kronqvist, Nina, Siau, Jia Wei, Ng, Aik Seng, Ghadessy, Farid J., Sabatier, Pierre, Vojtesek, Borivoj, Sarr, Médoune, Sahin, Cagla, Österlund, Nicklas, Ilag, Leopold L., Väänänen, Venla A., Sedimbi, Saikiran, Arsenian-Henriksson, Marie, Zubarev, Roman A., Nilsson, Lennart, Koeck, Philip J.B., Rising, Anna, Abelein, Axel, Fritz, Nicolas, Johansson, Jan, Lane, David P., Landreh, Michael
Published in Structure (London) (05.05.2022)
Published in Structure (London) (05.05.2022)
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Journal Article
Functional characterization of p53 pathway components in the ancient metazoan Trichoplax adhaerens
Siau, Jia Wei, Coffill, Cynthia R., Zhang, Weiyun Villien, Tan, Yaw Sing, Hundt, Juliane, Lane, David, Verma, Chandra, Ghadessy, Farid
Published in Scientific reports (28.09.2016)
Published in Scientific reports (28.09.2016)
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Journal Article
Conservative site-specific and single-copy transgenesis in human LINE-1 elements
Vijaya Chandra, Shree Harsha, Makhija, Harshyaa, Peter, Sabrina, Myint Wai, Cho Mar, Li, Jinming, Zhu, Jindong, Ren, Zhonglu, D'Alcontres, Martina Stagno, Siau, Jia Wei, Chee, Sharon, Ghadessy, Farid John, Dröge, Peter
Published in Nucleic acids research (07.04.2016)
Published in Nucleic acids research (07.04.2016)
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Journal Article
Directed evolution of λ integrase activity and specificity by genetic derepression
Siau, Jia Wei, Chee, Sharon, Makhija, Harshyaa, Wai, Cho Mar Myint, Chandra, Shree Harsha Vijaya, Peter, Sabrina, Dröge, Peter, Ghadessy, Farid J.
Published in Protein engineering, design and selection (01.07.2015)
Published in Protein engineering, design and selection (01.07.2015)
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Journal Article
Analysis of p53 binding to DNA by fluorescence imaging microscopy
Ong, Hwee Jing, Siau, Jia Wei, Zhang, Jing Bo, Hong, Minghui, Flotow, Horst, Ghadessy, Farid
Published in Micron (Oxford, England : 1993) (01.09.2012)
Published in Micron (Oxford, England : 1993) (01.09.2012)
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Journal Article
LAMBDA INTEGRASE MUTANTS AND METHODS OF THEIR USE
SIDDIQUI, Asim Azhar, GHADESSY, Farid John, MAKHIJA, Harshyaa, DRÖGE, Peter, SIAU, Jia Wei Yvonne, LAU, Sze Yi
Year of Publication 06.09.2024
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Year of Publication 06.09.2024
Patent
Mutants of the bacteriophage lambda integrase
Vijaya Chandra, Shree Harsh, Peter, Sabrina, Makhija, Harshyaa, Siau, Jia Wei, Droge, Peter, Ghadessy, Farid
Year of Publication 16.08.2022
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Year of Publication 16.08.2022
Patent
MUTANTS OF THE BACTERIOPHAGE LAMBDA INTEGRASE
DROGE, Peter, GHADESSY, Farid, MAKHIJA, Harshyaa, VIJAYA CHANDRA, SHREE HARSHA, PETER, Sabrina, SIAU, Jia Wei
Year of Publication 29.07.2020
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Year of Publication 29.07.2020
Patent