Hormone-induced mitochondrial fission is utilized by brown adipocytes as an amplification pathway for energy expenditure
Wikstrom, Jakob D, Mahdaviani, Kiana, Liesa, Marc, Sereda, Samuel B, Si, Yaguang, Las, Guy, Twig, Gilad, Petrovic, Natasa, Zingaretti, Cristina, Graham, Adam, Cinti, Saverio, Corkey, Barbara E, Cannon, Barbara, Nedergaard, Jan, Shirihai, Orian S
Published in The EMBO journal (03.03.2014)
Published in The EMBO journal (03.03.2014)
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Journal Article
Differential Aspartate Usage Identifies a Subset of Cancer Cells Particularly Dependent on OGDH
Allen, Eric L., Ulanet, Danielle B., Pirman, David, Mahoney, Christopher E., Coco, John, Si, Yaguang, Chen, Ying, Huang, Lingling, Ren, Jinmin, Choe, Sung, Clasquin, Michelle F., Artin, Erin, Fan, Zi Peng, Cianchetta, Giovanni, Murtie, Joshua, Dorsch, Marion, Jin, Shengfang, Smolen, Gromoslaw A.
Published in Cell reports (Cambridge) (11.10.2016)
Published in Cell reports (Cambridge) (11.10.2016)
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Journal Article
Respiration in Adipocytes is Inhibited by Reactive Oxygen Species
Wang, Tong, Si, Yaguang, Shirihai, Orian S., Si, Huiqing, Schultz, Vera, Corkey, Richard F., Hu, Liping, Deeney, Jude T., Guo, Wen, Corkey, Barbara E.
Published in Obesity (Silver Spring, Md.) (01.08.2010)
Published in Obesity (Silver Spring, Md.) (01.08.2010)
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Journal Article
AG-348 enhances pyruvate kinase activity in red blood cells from patients with pyruvate kinase deficiency
Kung, Charles, Hixon, Jeff, Kosinski, Penelope A., Cianchetta, Giovanni, Histen, Gavin, Chen, Yue, Hill, Collin, Gross, Stefan, Si, Yaguang, Johnson, Kendall, DeLaBarre, Byron, Luo, Zhiyong, Gu, Zhiwei, Yao, Gui, Tang, Huachun, Fang, Cheng, Xu, Yingxia, Lv, Xiaobing, Biller, Scott, Su, Shin-San Michael, Yang, Hua, Popovici-Muller, Janeta, Salituro, Francesco, Silverman, Lee, Dang, Lenny
Published in Blood (14.09.2017)
Published in Blood (14.09.2017)
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Journal Article
Abstract 3094: Discovery of a HeliconTM peptide inhibitor of the beta-catenin-TCF interaction with in vivo activity
White, Brian H., Si, Yaguang, Cappucci, Sarah, Li, Zhi, Ramirez, Jessica D., Ponthier, Charles M., Visness, Erica, Du, Peicheng, Choi, Minjung, Beerepoot, Pieter C., Ortet, Paula C., Jewett, Ivan T., Alfaro-Lopez, Josue, Agarwal, Sorabh, La, Daniel, Fulgham, Aaron, McGee, John H., Orford, Keith, Hurov, Jonathan B., Tremblay, Martin R., Verdine, Gregory L.
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
Abstract 4972: Anti-tumor activity of Helicon inhibitors of Β-catenin-TCF interaction in patient-derived xenograft models
Si, YaGuang, Choi, Minjung, Han, Xinwei, White, Brian, Wu, Ziyang, Visness, Erica, Beerepoot, Pieter, Jaensch, Elizabeth, Ramirez, Jessica, Ponthier, Charles, Han, Xiaogang, Ortet, Paula, Du, Peicheng, Agarwal, Sorabh, Lech, Mirek, Fulgham, Aaron, Cappucci, Sarah, Li, Zhi, McGee, John, Yu, Lihua, Tremblay, Martin, Orford, Keith, Verdine, Gregory, Hurov, Jonathan
Published in Cancer research (Chicago, Ill.) (04.04.2023)
Published in Cancer research (Chicago, Ill.) (04.04.2023)
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Journal Article
AG-348 Activation of Pyruvate Kinase in Vivo Enhances Red Cell Glycolysis in Mice
Kung, Charles, Hill, Collin, Chen, Yue, Jha, Abhishek, Kosinski, Penelope, Clasquin, Michelle, Si, Yaguang, Kim, Hyeryun, Hixon, Jeff, Dang, Lenny, Agresta, Sam, Silverman, Lee, Yang, Hua
Published in Blood (06.12.2014)
Published in Blood (06.12.2014)
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Journal Article
Abstract 345: Development of a novel and direct peptide Helicon࣪ inhibitor of β-catenin-TCF interaction with in vivo validation of transcriptional modulation and anti-tumor activity
Si, Yaguang, White, Brian, Cappucci, Sarah, Ramirez, Jessica, Ponthier, Charles, Visness, Erica, Ling, Kevin, Du, Peicheng, Choi, Minjung, Thomson, Ty, Alfaro-Lopez, Josue, Beerepoot, Pieter, Agarwal, Sorabh, Ortet, Paula, Lech, Miroslaw, Li, Zhi, Olokpa, Voké, Jewett, Ivan, La, Daniel, Yu, Lihua, McGee, John, Tremblay, Martin, Hurov, Jonathan, Verdine, Greg
Published in Cancer research (Chicago, Ill.) (15.06.2022)
Published in Cancer research (Chicago, Ill.) (15.06.2022)
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Journal Article
A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model
Wang, Fang, Travins, Jeremy, Lin, Zhizhong, Si, Yaguang, Chen, Yue, Powe, Josh, Murray, Stuart, Zhu, Dongwei, Artin, Erin, Gross, Stefan, Santiago, Stephanie, Steadman, Mya, Kernytsky, Andrew, Straley, Kimberly, Lu, Chenming, Pop, Ana, Struys, Eduard A., Jansen, Erwin E. W., Salomons, Gajja S., David, Muriel D., Quivoron, Cyril, Penard-Lacronique, Virginie, Regan, Karen S., Liu, Wei, Dang, Lenny, Yang, Hua, Silverman, Lee, Agresta, Samuel, Dorsch, Marion, Biller, Scott, Yen, Katharine, Cang, Yong, Su, Shin-San Michael, Jin, Shengfang
Published in Journal of inherited metabolic disease (01.11.2016)
Published in Journal of inherited metabolic disease (01.11.2016)
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Journal Article
Small Molecule Activation Of Pyruvate Kinase Normalizes Metabolic Activity In Red Cells From Patients With Pyruvate Kinase Deficiency-Associated Hemolytic Anemia
Kung, Charles, Hixon, Jeff, Kosinski, Penelope, Histen, Gavin, Hill, Collin, Si, Yaguang, Kernytsky, Andrew, Chen, Yue, DeLaBarre, Byron, Clasquin, Michelle, Ho, Helen, Cossor, Furha I., Neufeld, Ellis J., Salituro, Frank, Popovici-Muller, Janeta, Agresta, Samuel, Silverman, Lee, Dang, Lenny
Published in Blood (15.11.2013)
Published in Blood (15.11.2013)
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Journal Article
Effect of uncoupling protein-1 expression on 3T3-L1 adipocyte gene expression
Senocak, Fatih S., Si, Yaguang, Moya, Colby, Russell, William K., Russell, David H., Lee, Kyongbum, Jayaraman, Arul
Published in FEBS letters (22.12.2007)
Published in FEBS letters (22.12.2007)
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