Complete loss of H3K9 methylation dissolves mouse heterochromatin organization
Montavon, Thomas, Shukeir, Nicholas, Erikson, Galina, Engist, Bettina, Onishi-Seebacher, Megumi, Ryan, Devon, Musa, Yaarub, Mittler, Gerhard, Meyer, Alexandra Graff, Genoud, Christel, Jenuwein, Thomas
Published in Nature communications (16.07.2021)
Published in Nature communications (16.07.2021)
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Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation
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Published in eLife (01.08.2017)
Published in eLife (01.08.2017)
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Prdm3 and Prdm16 are H3K9me1 Methyltransferases Required for Mammalian Heterochromatin Integrity
Pinheiro, Inês, Margueron, Raphaël, Shukeir, Nicholas, Eisold, Michael, Fritzsch, Christoph, Richter, Florian M., Mittler, Gerhard, Genoud, Christel, Goyama, Susumu, Kurokawa, Mineo, Son, Jinsook, Reinberg, Danny, Lachner, Monika, Jenuwein, Thomas
Published in Cell (31.08.2012)
Published in Cell (31.08.2012)
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H1 linker histones silence repetitive elements by promoting both histone H3K9 methylation and chromatin compaction
Healton, Sean E., Pinto, Hugo D., Mishra, Laxmi N., Hamilton, Gregory A., Wheat, Justin C., Swist-Rosowska, Kalina, Shukeir, Nicholas, Dou, Yali, Steidl, Ulrich, Jenuwein, Thomas, Gamble, Matthew J., Skoultchi, Arthur I.
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (23.06.2020)
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MeCP2 binds to methylated DNA independently of phase separation and heterochromatin organisation
Pantier, Raphaël, Brown, Megan, Han, Sicheng, Paton, Katie, Meek, Stephen, Montavon, Thomas, Shukeir, Nicholas, McHugh, Toni, Kelly, David A, Hochepied, Tino, Libert, Claude, Jenuwein, Thomas, Burdon, Tom, Bird, Adrian
Published in Nature communications (08.05.2024)
Published in Nature communications (08.05.2024)
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A transcription factor-based mechanism for mouse heterochromatin formation
Bulut-Karslioglu, Aydan, Perrera, Valentina, Scaranaro, Manuela, de la Rosa-Velazquez, Inti Alberto, van de Nobelen, Suzanne, Shukeir, Nicholas, Popow, Johannes, Gerle, Borbala, Opravil, Susanne, Pagani, Michaela, Meidhof, Simone, Brabletz, Thomas, Manke, Thomas, Lachner, Monika, Jenuwein, Thomas
Published in Nature structural & molecular biology (01.10.2012)
Published in Nature structural & molecular biology (01.10.2012)
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Mammalian Su(var) genes in chromatin control
Fodor, Barna D, Shukeir, Nicholas, Reuter, Gunter, Jenuwein, Thomas
Published in Annual review of cell and developmental biology (10.11.2010)
Published in Annual review of cell and developmental biology (10.11.2010)
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Journal Article
Alteration of the methylation status of tumor-promoting genes decreases prostate cancer cell invasiveness and tumorigenesis in vitro and in vivo
SHUKEIR, Nicholas, PAKNESHAN, Pouya, GAOPING CHEN, SZYF, Moshe, RABBANI, Shafaat A
Published in Cancer research (Chicago, Ill.) (15.09.2006)
Published in Cancer research (Chicago, Ill.) (15.09.2006)
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m6A RNA methylation of major satellite repeat transcripts facilitates chromatin association and RNA:DNA hybrid formation in mouse heterochromatin
Duda, Katarzyna J, Ching, Reagan W, Jerabek, Lisa, Shukeir, Nicholas, Erikson, Galina, Engist, Bettina, Onishi-Seebacher, Megumi, Perrera, Valentina, Richter, Florian, Mittler, Gerhard, Fritz, Katharina, Helm, Mark, Knuckles, Philip, Bühler, Marc, Jenuwein, Thomas
Published in Nucleic acids research (04.06.2021)
Published in Nucleic acids research (04.06.2021)
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Up-regulation of Wnt-1 and β-catenin production in patients with advanced metastatic prostate carcinoma: Potential pathogenetic and prognostic implications
GAOPING CHEN, SHUKEIR, Nicholas, POTTI, Anil, SIRCAR, Kanishka, APRIKIAN, Armen, GOLTZMAN, David, RABBANI, Shafaat A
Published in Cancer (15.09.2004)
Published in Cancer (15.09.2004)
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Histone Demethylase UTX-1 Regulates C. elegans Life Span by Targeting the Insulin/IGF-1 Signaling Pathway
Jin, Chunyu, Li, Jing, Green, Christopher D., Yu, Xiaoming, Tang, Xia, Han, Dali, Xian, Bo, Wang, Dan, Huang, Xinxin, Cao, Xiongwen, Yan, Zheng, Hou, Lei, Liu, Jiancheng, Shukeir, Nicholas, Khaitovich, Philipp, Chen, Charlie D., Zhang, Hong, Jenuwein, Thomas, Han, Jing-Dong J.
Published in Cell metabolism (03.08.2011)
Published in Cell metabolism (03.08.2011)
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Journal Article
A transcription factor-based mechanism for mouse heterochromatin formation
Bulut-karslioglu, Aydan, Perrera, Valentina, Scaranaro, Manuela, De La Rosa-velazquez, Inti Alberto, Van De Nobelen, Suzanne, Shukeir, Nicholas, Popow, Johannes, Gerle, Borbala, Opravil, Susanne, Pagani, Michaela, Meidhof, Simone, Brabletz, Thomas, Manke, Thomas, Lachner, Monika, Jenuwein, Thomas
Published in Nature structural & molecular biology (01.02.2013)
Published in Nature structural & molecular biology (01.02.2013)
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Erratum: A transcription factor–based mechanism for mouse heterochromatin formation
Bulut-Karslioglu, Aydan, Perrera, Valentina, Scaranaro, Manuela, de la Rosa-Velazquez, Inti Alberto, van de Nobelen, Suzanne, Shukeir, Nicholas, Popow, Johannes, Gerle, Borbala, Opravil, Susanne, Pagani, Michaela, Meidhof, Simone, Brabletz, Thomas, Manke, Thomas, Lachner, Monika, Jenuwein, Thomas
Published in Nature structural & molecular biology (05.02.2013)
Published in Nature structural & molecular biology (05.02.2013)
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Prostate secretory protein PSP-94 decreases tumor growth and hypercalcemia of malignancy in a syngenic in vivo model of prostate cancer
SHUKEIR, Nicholas, ARAKELIAN, Ani, KADHIM, Salam, GARDE, Seema, RABBANI, Shafaat A
Published in Cancer research (Chicago, Ill.) (01.05.2003)
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Published in Cancer research (Chicago, Ill.) (01.05.2003)
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A synthetic 15-mer peptide (PCK3145) derived from prostate secretory protein can reduce tumor growth, experimental skeletal metastases, and malignancy-associated hypercalcemia
SHUKEIR, Nicholas, ARAKELIAN, Ani, GAOPING CHEN, GARDE, Seema, RUIZ, Marcia, PANCHAL, Chandra, RABBANI, Shafaat A
Published in Cancer research (Chicago, Ill.) (01.08.2004)
Published in Cancer research (Chicago, Ill.) (01.08.2004)
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Expression of Concern: Up‐regulation of Wnt‐1 and β ‐catenin production in patients with advanced metastatic prostate carcinoma
Chen, Gaoping, Shukeir, Nicholas, Potti, Anil, Sircar, Kanishka, Aprikian, Armen, Goltzman, David, Rabbani, Shafaat A.
Published in Cancer (15.09.2004)
Published in Cancer (15.09.2004)
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PSP-94: use for treatment of hypercalcemia and bone metastasis
CHANDRA J PANCHAL, NICHOLAS SHUKEIR, SHAFAAT AHMED RABBANI, CHRISTOPHER NEWMAN
Year of Publication 10.01.2008
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Year of Publication 10.01.2008
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