Long-term safety of dichloroacetate in congenital lactic acidosis
Abdelmalak, Monica, Lew, Alicia, Ramezani, Ryan, Shroads, Albert L., Coats, Bonnie S., Langaee, Taimour, Shankar, Meena N., Neiberger, Richard E., Subramony, S.H., Stacpoole, Peter W.
Published in Molecular genetics and metabolism (01.06.2013)
Published in Molecular genetics and metabolism (01.06.2013)
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heme precursor delta-aminolevulinate blocks peripheral myelin formation
Felitsyn, Natalia, McLeod, Colin, Shroads, Albert L, Stacpoole, Peter W, Notterpek, Lucia
Published in Journal of neurochemistry (01.09.2008)
Published in Journal of neurochemistry (01.09.2008)
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Journal Article
Age-Dependent Kinetics and Metabolism of Dichloroacetate: Possible Relevance to Toxicity
Shroads, Albert L, Guo, Xu, Dixit, Vaishali, Liu, Hui-Ping, James, Margaret O, Stacpoole, Peter W
Published in The Journal of pharmacology and experimental therapeutics (01.03.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.03.2008)
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Journal Article
Pharmacokinetics of Oral Dichloroacetate in Dogs
Maisenbacher III, Herbert W., Shroads III, Albert L., Zhong, Guo, Daigle, Adam D., Abdelmalak, Monica M., Samper, Ivan Sosa, Mincey, Brandy D., James, Margaret O., Stacpoole, Peter W.
Published in Journal of biochemical and molecular toxicology (01.12.2013)
Published in Journal of biochemical and molecular toxicology (01.12.2013)
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INHIBITION AND RECOVERY OF RAT HEPATIC GLUTATHIONE S-TRANSFERASE ZETA AND ALTERATION OF TYROSINE METABOLISM FOLLOWING DICHLOROACETATE EXPOSURE AND WITHDRAWAL
Guo, Xu, Dixit, Vaishali, Liu, Huiping, Shroads, Albert L, Henderson, George N, James, Margaret O, Stacpoole, Peter W
Published in Drug metabolism and disposition (01.01.2006)
Published in Drug metabolism and disposition (01.01.2006)
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Journal Article
Unified gas chromatographic–mass spectrometric method for quantitating tyrosine metabolites in urine and plasma
Shroads, Albert L, Henderson, George N, Cheung, Jang, James, Margaret O, Stacpoole, Peter W
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.09.2004)
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (05.09.2004)
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Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children
Stacpoole, Peter W, Kerr, Douglas S, Barnes, Carie, Bunch, S Terri, Carney, Paul R, Fennell, Eileen M, Felitsyn, Natalia M, Gilmore, Robin L, Greer, Melvin, Henderson, George N, Hutson, Alan D, Neiberger, Richard E, O'Brien, Ralph G, Perkins, Leigh Ann, Quisling, Ronald G, Shroads, Albert L, Shuster, Jonathan J, Silverstein, Janet H, Theriaque, Douglas W, Valenstein, Edward
Published in Pediatrics (Evanston) (01.05.2006)
Published in Pediatrics (Evanston) (01.05.2006)
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Journal Article
Human polymorphisms in the glutathione transferase zeta 1/maleylacetoacetate isomerase gene influence the toxicokinetics of dichloroacetate
Shroads, Albert L, Langaee, Taimour, Coats, Bonnie S, Kurtz, Tracie L, Bullock, John R, Weithorn, David, Gong, Yan, Wagner, David A, Ostrov, David A, Johnson, Julie A, Stacpoole, Peter W
Published in Journal of clinical pharmacology (01.06.2012)
Published in Journal of clinical pharmacology (01.06.2012)
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Journal Article
Population Pharmacokinetics of Intramuscular Quinine in Children with Severe Malaria
KRISHNA, Sanjeev, NAGARAJA, Nelamangala V, DERENDORF, Hartmut, STACPOOLE, Peter W, PLANCHE, Tim, AGBENYEGA, Tsiri, BEDO-ADDO, George, ANSONG, Daniel, OWUSU-OFORI, Alex, SHROADS, Albert L, HENDERSON, George, HUTSON, Alan
Published in Antimicrobial Agents and Chemotherapy (01.06.2001)
Published in Antimicrobial Agents and Chemotherapy (01.06.2001)
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Journal Article
Peripheral Neuropathy in Rats Exposed to Dichloroacetate
Calcutt, Nigel A, Lopez, Veronica L, Bautista, Arjel D, Mizisin, Leah M, Torres, Brenda R, Shroads, Albert L, Mizisin, Andrew P, Stacpoole, Peter W
Published in Journal of neuropathology and experimental neurology (01.09.2009)
Published in Journal of neuropathology and experimental neurology (01.09.2009)
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Journal Article
Chloral hydrate, through biotransformation to dichloroacetate, inhibits maleylacetoacetate isomerase and tyrosine catabolism in humans
Shroads, Albert L., Coats, Bonnie S., Langaee, Taimour, Shuster, Jonathan J., Stacpoole, Peter W.
Published in Drug metabolism and drug interactions (01.03.2015)
Published in Drug metabolism and drug interactions (01.03.2015)
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Journal Article
Pharmacologic or genetic ablation of maleylacetoacetate isomerase increases levels of toxic tyrosine catabolites in rodents
Ammini, Chandramohan V, Fernandez-Canon, Jose, Shroads, Albert L, Cornett, Rachel, Cheung, Jang, James, Margaret O, Henderson, George N, Grompe, Markus, Stacpoole, Peter W
Published in Biochemical pharmacology (15.11.2003)
Published in Biochemical pharmacology (15.11.2003)
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Journal Article
Population kinetics, efficacy, and safety of dichloroacetate for lactic acidosis due to severe malaria in children
Agbenyega, Tsiri, Planche, Tim, Bedu-Addo, George, Ansong, Daniel, Owusu-Ofori, Alex, Bhattaram, Venkatesh A, Nagaraja, Nelamangala V, Shroads, Albert L, Henderson, George N, Hutson, Alan D, Derendorf, Hartmut, Krishna, Sanjeev, Stacpoole, Peter W
Published in Journal of clinical pharmacology (01.04.2003)
Published in Journal of clinical pharmacology (01.04.2003)
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Journal Article
Long-term safety of dichloroacetate in congenital lactic acidosis
Abdelmalak, Monica, Lew, Alicia, Ramezani, Ryan, Shroads, Albert L., Coats, Bonnie S., Shankar, Meena N., Stacpoole, Peter W.
Published in Mitochondrion (01.09.2012)
Published in Mitochondrion (01.09.2012)
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Journal Article
Age-Dependent Kinetics and Metabolism of Dichloroacetate: Possible Relevance to Toxicity
Shroads, Albert L., Guo, Xu, Dixit, Vaishali, Liu, Hui-Ping, James, Margaret O., Stacpoole, Peter W.
Published in The Journal of pharmacology and experimental therapeutics (20.12.2007)
Published in The Journal of pharmacology and experimental therapeutics (20.12.2007)
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Journal Article
36. Age-dependent kinetics and metabolism of dichloroacetate: Possible relevance to toxicity
Shroads, Albert L., Guo, Xu, Dixit, Vaishali, Liu, Hui-Ping, James, Margaret O., Stacpoole, Peter W.
Published in Mitochondrion (01.02.2009)
Published in Mitochondrion (01.02.2009)
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Journal Article
Inhibition of Glutathione S-Transferase ζ and Tyrosine Metabolism by Dichloroacetate: A Potential Unifying Mechanism for Its Altered Biotransformation and Toxicity
Cornett, Rachel, James, Margaret O., Henderson, George N., Cheung, Jang, Shroads, Albert L., Stacpoole, Peter W.
Published in Biochemical and biophysical research communications (07.09.1999)
Published in Biochemical and biophysical research communications (07.09.1999)
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