Fibroblast activation protein targeted therapy using [177Lu]FAPI-46 compared with [225Ac]FAPI-46 in a pancreatic cancer model
Liu, Yuwei, Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Naka, Sadahiro, Ooe, Kazuhiro, Toyoshima, Atsushi, Nagata, Kojiro, Haberkorn, Uwe, Kratochwil, Clemens, Shinohara, Atsushi, Hatazawa, Jun, Giesel, Frederik
Published in European journal of nuclear medicine and molecular imaging (01.02.2022)
Published in European journal of nuclear medicine and molecular imaging (01.02.2022)
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Journal Article
Extended single-dose toxicity study of [211At]NaAt in mice for the first-in-human clinical trial of targeted alpha therapy for differentiated thyroid cancer
Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Ooe, Kazuhiro, Liu, Yuwei, Kurimoto, Kenta, Murai, Takashi, Shidahara, Yuka, Okuma, Kenji, Takeuchi, Masanori, Nishide, Masayuki, Toyoshima, Atsushi, Shinohara, Atsushi, Shirakami, Yoshifumi
Published in Annals of nuclear medicine (01.06.2021)
Published in Annals of nuclear medicine (01.06.2021)
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Journal Article
Neopentyl Glycol as a Scaffold to Provide Radiohalogenated Theranostic Pairs of High In Vivo Stability
Suzuki, Hiroyuki, Kaizuka, Yuta, Tatsuta, Maho, Tanaka, Hiroshi, Washiya, Nana, Shirakami, Yoshifumi, Ooe, Kazuhiro, Toyoshima, Atsushi, Watabe, Tadashi, Teramoto, Takahiro, Sasaki, Ichiro, Watanabe, Shigeki, Ishioka, Noriko S, Hatazawa, Jun, Uehara, Tomoya, Arano, Yasushi
Published in Journal of medicinal chemistry (11.11.2021)
Published in Journal of medicinal chemistry (11.11.2021)
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Journal Article
Synthesis of [211At]4-astato-L-phenylalanine by dihydroxyboryl-astatine substitution reaction in aqueous solution
Shirakami, Yoshifumi, Watabe, Tadashi, Obata, Honoka, Kaneda, Kazuko, Ooe, Kazuhiro, Liu, Yuwei, Teramoto, Takahiro, Toyoshima, Atsushi, Shinohara, Atsushi, Shimosegawa, Eku, Hatazawa, Jun, Fukase, Koichi
Published in Scientific reports (21.06.2021)
Published in Scientific reports (21.06.2021)
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Journal Article
Dioxetane Derivative Containing Carboxy Group as a Chemiluminophore‐Introducing Reagent
Nohara, Yukie, Masuda, Shun, Kaneda‐Nakashima, Kazuko, Shirakami, Yoshifumi, Matsumoto, Masakatsu, Yoshiya, Taku
Published in Chembiochem : a European journal of chemical biology (16.12.2022)
Published in Chembiochem : a European journal of chemical biology (16.12.2022)
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Journal Article
Effect to Therapy of Sodium-Iodine Symporter Expression by Alpha-Ray Therapeutic Agent via Sodium/Iodine Symporter
Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Watabe, Tadashi, Ooe, Kazuhiro, Yoshimura, Takashi, Toyoshima, Atsushi, Wang, Yang, Haba, Hiromitsu, Fukase, Koichi
Published in International journal of molecular sciences (07.12.2022)
Published in International journal of molecular sciences (07.12.2022)
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Journal Article
Comparison of the Therapeutic Effects of [211At]NaAt and [131I]NaI in an NIS-Expressing Thyroid Cancer Mouse Model
Watabe, Tadashi, Liu, Yuwei, Kaneda-Nakashima, Kazuko, Sato, Tatsuhiko, Shirakami, Yoshifumi, Ooe, Kazuhiro, Toyoshima, Atsushi, Shimosegawa, Eku, Wang, Yang, Haba, Hiromitsu, Nakano, Takashi, Shinohara, Atsushi, Hatazawa, Jun
Published in International journal of molecular sciences (21.08.2022)
Published in International journal of molecular sciences (21.08.2022)
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Journal Article
Comparison of Nuclear Medicine Therapeutics Targeting PSMA among Alpha-Emitting Nuclides
Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Kadonaga, Yuichiro, Watabe, Tadashi, Ooe, Kazuhiro, Yin, Xiaojie, Haba, Hiromitsu, Shirasaki, Kenji, Kikunaga, Hidetoshi, Tsukada, Kazuaki, Toyoshima, Atsushi, Cardinale, Jens, Giesel, Frederik L, Fukase, Koichi
Published in International journal of molecular sciences (01.01.2024)
Published in International journal of molecular sciences (01.01.2024)
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Journal Article
Preclinical Evaluation of Biodistribution and Toxicity of [ 211 At]PSMA-5 in Mice and Primates for the Targeted Alpha Therapy against Prostate Cancer
Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Kadonaga, Yuichiro, Ooe, Kazuhiro, Sampunta, Thosapol, Hirose, Naoki, Yin, Xiaojie, Haba, Hiromitsu, Kon, Yukiyoshi, Toyoshima, Atsushi, Cardinale, Jens, Giesel, Frederik L, Fukase, Koichi, Tomiyama, Noriyuki, Shirakami, Yoshifumi
Published in International journal of molecular sciences (01.06.2024)
Published in International journal of molecular sciences (01.06.2024)
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Journal Article
Targeted alpha therapy using astatine ( 211 At)-labeled phenylalanine: A preclinical study in glioma bearing mice
Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Liu, Yuwei, Ooe, Kazuhiro, Teramoto, Takahiro, Toyoshima, Atsushi, Shimosegawa, Eku, Nakano, Takashi, Kanai, Yoshikatsu, Shinohara, Atsushi, Hatazawa, Jun
Published in Oncotarget (14.04.2020)
Published in Oncotarget (14.04.2020)
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Journal Article
Evaluation of Astatine-211-Labeled Fibroblast Activation Protein Inhibitor (FAPI): Comparison of Different Linkers with Polyethylene Glycol and Piperazine
Aso, Ayaka, Nabetani, Hinako, Matsuura, Yoshifumi, Kadonaga, Yuichiro, Shirakami, Yoshifumi, Watabe, Tadashi, Yoshiya, Taku, Mochizuki, Masayoshi, Ooe, Kazuhiro, Kawakami, Atsuko, Jinno, Naoya, Toyoshima, Atsushi, Haba, Hiromitsu, Wang, Yang, Cardinale, Jens, Giesel, Frederik Lars, Shimoyama, Atsushi, Kaneda-Nakashima, Kazuko, Fukase, Koichi
Published in International journal of molecular sciences (12.05.2023)
Published in International journal of molecular sciences (12.05.2023)
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Journal Article
Development of high-resolution YAP(Ce) x-ray camera for the imaging of astatine-211(At-211) in small animals
Nakanishi, Kouhei, Yamamoto, Seiichi, Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Ooe, Kazuhiro, Toyoshima, Atsushi, Shinohara, Atsushi, Teramoto, Takahiro, Hatazawa, Jun, Kamada, Kei, Yoshikawa, Akira
Published in Medical physics (Lancaster) (01.11.2020)
Published in Medical physics (Lancaster) (01.11.2020)
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Journal Article
Comparative evaluation of transport mechanisms of trans -1-amino-3-[18 F]fluorocyclobutanecarboxylic acid and l -[methyl-11 C]methionine in human glioma cell lines
Ono, Masahiro, Oka, Shuntaro, Okudaira, Hiroyuki, Schuster, David M, Goodman, Mark M, Kawai, Keiichi, Shirakami, Yoshifumi
Published in Brain research (16.10.2013)
Published in Brain research (16.10.2013)
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Journal Article
Mathematical Model for Evaluation of Tumor Response in Targeted Radionuclide Therapy with 211At Using Implanted Mouse Tumor
Yonekura, Yoshiharu, Toki, Hiroshi, Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Ooe, Kazuhiro, Toyoshima, Atsushi, Nakajima, Hiroo, Tomiyama, Noriyuki, Bando, Masako
Published in International journal of molecular sciences (15.12.2022)
Published in International journal of molecular sciences (15.12.2022)
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Journal Article
α‐Emitting cancer therapy using 211At‐AAMT targeting LAT1
Kaneda‐Nakashima, Kazuko, Zhang, ZiJian, Manabe, Yoshiyuki, Shimoyama, Atsushi, Kabayama, Kazuya, Watabe, Tadashi, Kanai, Yoshikatsu, Ooe, Kazuhiro, Toyoshima, Atsushi, Shirakami, Yoshifumi, Yoshimura, Takashi, Fukuda, Mitsuhiro, Hatazawa, Jun, Nakano, Takashi, Fukase, Koichi, Shinohara, Atsushi
Published in Cancer science (01.03.2021)
Published in Cancer science (01.03.2021)
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Journal Article
Theranostics Targeting Fibroblast Activation Protein in the Tumor Stroma: 64Cu- and 225Ac-Labeled FAPI-04 in Pancreatic Cancer Xenograft Mouse Models
Watabe, Tadashi, Liu, Yuwei, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Lindner, Thomas, Ooe, Kazuhiro, Toyoshima, Atsushi, Nagata, Kojiro, Shimosegawa, Eku, Haberkorn, Uwe, Kratochwil, Clemens, Shinohara, Atsushi, Giesel, Frederik, Hatazawa, Jun
Published in The Journal of nuclear medicine (1978) (01.04.2020)
Published in The Journal of nuclear medicine (1978) (01.04.2020)
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Journal Article
Development and Utility of an Imaging System for Internal Dosimetry of Astatine-211 in Mice
Yagishita, Atsushi, Katsuragawa, Miho, Takeda, Shin'ichiro, Shirakami, Yoshifumi, Ooe, Kazuhiro, Toyoshima, Atsushi, Takahashi, Tadayuki, Watabe, Tadashi
Published in Bioengineering (Basel) (26.12.2023)
Published in Bioengineering (Basel) (26.12.2023)
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Journal Article
Preclinical Evaluation of Radiation-Induced Toxicity in Targeted Alpha Therapy Using [211At] NaAt in Mice: A Revisit
Liu, Yuwei, Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Ooe, Kazuhiro, Shirakami, Yoshifumi, Toyoshima, Atsushi, Shimosegawa, Eku, Nakano, Takashi, Shinohara, Atsushi, Hatazawa, Jun
Published in Translational oncology (01.04.2020)
Published in Translational oncology (01.04.2020)
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Journal Article
Production of [211At]NaAt solution under GMP compliance for investigator-initiated clinical trial
Naka, Sadahiro, Ooe, Kazuhiro, Shirakami, Yoshifumi, Kurimoto, Kenta, Sakai, Toshihiro, Takahashi, Kazuhiro, Toyoshima, Atsushi, Wang, Yang, Haba, Hiromitsu, Kato, Hiroki, Tomiyama, Noriyuki, Watabe, Tadashi
Published in EJNMMI radiopharmacy and chemistry (15.04.2024)
Published in EJNMMI radiopharmacy and chemistry (15.04.2024)
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