Polygenic architecture informs potential vulnerability to drug-induced liver injury
Koido, Masaru, Kawakami, Eri, Fukumura, Junko, Noguchi, Yui, Ohori, Momoko, Nio, Yasunori, Nicoletti, Paola, Aithal, Guruprasad P, Daly, Ann K, Watkins, Paul B, Anayama, Hisashi, Dragan, Yvonne, Shinozawa, Tadahiro, Takebe, Takanori
Published in Nature medicine (01.10.2020)
Published in Nature medicine (01.10.2020)
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Comparative analysis of neurofilament light chain levels in the serum and cerebrospinal fluid in rats subjected to partial sciatic nerve ligation
SANO, Tomoya, MASUDA, Yasushi, YASUNO, Hironobu, WATANABE, Takeshi, SHINOZAWA, Tadahiro
Published in Journal of Toxicologic Pathology (01.01.2023)
Published in Journal of Toxicologic Pathology (01.01.2023)
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Cell-based high-throughput screening for the evaluation of reactive metabolite formation potential
Harada, Kosuke, Kohara, Hiroshi, Yukawa, Tomoya, Matsumiya, Kouta, Shinozawa, Tadahiro
Published in Toxicology in vitro (01.08.2021)
Published in Toxicology in vitro (01.08.2021)
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Cell-based two-dimensional morphological assessment system to predict cancer drug-induced cardiotoxicity using human induced pluripotent stem cell-derived cardiomyocytes
Matsui, Toshikatsu, Miyamoto, Kazumasa, Yamanaka, Kazunori, Okai, Yoshiko, Kaushik, Emily Pfeiffer, Harada, Kousuke, Wagoner, Matthew, Shinozawa, Tadahiro
Published in Toxicology and applied pharmacology (15.11.2019)
Published in Toxicology and applied pharmacology (15.11.2019)
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High-Throughput Screening to Evaluate Inhibition of Bile Acid Transporters Using Human Hepatocytes Isolated From Chimeric Mice
Kohara, Hiroshi, Bajaj, Piyush, Yamanaka, Kazunori, Miyawaki, Akimitsu, Harada, Kosuke, Miyamoto, Kazumasa, Matsui, Toshikatsu, Okai, Yoshiko, Wagoner, Matthew, Shinozawa, Tadahiro
Published in Toxicological sciences (01.02.2020)
Published in Toxicological sciences (01.02.2020)
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Identifying the dataset to define the optimal timing of histopathological examination for central nervous system toxicity in MPTP-induced Parkinson’s disease monkey model
Yasuno, Hironobu, Masuda, Yasushi, Ozaki, Harushige, Sano, Tomoya, Shinozawa, Tadahiro, Watanabe, Takeshi
Published in Journal of Toxicologic Pathology (01.01.2023)
Published in Journal of Toxicologic Pathology (01.01.2023)
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Recapitulation of Clinical Individual Susceptibility to Drug-Induced QT Prolongation in Healthy Subjects Using iPSC-Derived Cardiomyocytes
Shinozawa, Tadahiro, Nakamura, Koki, Shoji, Masanobu, Morita, Maya, Kimura, Maya, Furukawa, Hatsue, Ueda, Hiroki, Shiramoto, Masanari, Matsuguma, Kyoko, Kaji, Yoshikazu, Ikushima, Ippei, Yono, Makoto, Liou, Shyh-Yuh, Nagai, Hirofumi, Nakanishi, Atsushi, Yamamoto, Keiji, Izumo, Seigo
Published in Stem cell reports (14.02.2017)
Published in Stem cell reports (14.02.2017)
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Determination of appropriate stage of human-induced pluripotent stem cell-derived cardiomyocytes for drug screening and pharmacological evaluation in vitro
Shinozawa, Tadahiro, Imahashi, Kenichi, Sawada, Hiroshi, Furukawa, Hatsue, Takami, Kenji
Published in Journal of biomolecular screening (01.10.2012)
Published in Journal of biomolecular screening (01.10.2012)
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A novel purification method of murine embryonic stem cell- and human-induced pluripotent stem cell-derived cardiomyocytes by simple manual dissociation
Shinozawa, Tadahiro, Furukawa, Hatsue, Sato, Eimei, Takami, Kenji
Published in Journal of biomolecular screening (01.06.2012)
Published in Journal of biomolecular screening (01.06.2012)
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Derivation of rat embryonic stem cells and generation of protease-activated receptor-2 knockout rats
Yamamoto, Satoshi, Nakata, Mitsugu, Sasada, Reiko, Ooshima, Yuki, Yano, Takashi, Shinozawa, Tadahiro, Tsukimi, Yasuhiro, Takeyama, Michiyasu, Matsumoto, Yoshio, Hashimoto, Tadatoshi
Published in Transgenic research (01.08.2012)
Published in Transgenic research (01.08.2012)
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High-Fidelity Drug-Induced Liver Injury Screen Using Human Pluripotent Stem Cell–Derived Organoids
Shinozawa, Tadahiro, Kimura, Masaki, Cai, Yuqi, Saiki, Norikazu, Yoneyama, Yosuke, Ouchi, Rie, Koike, Hiroyuki, Maezawa, Mari, Zhang, Ran-Ran, Dunn, Andrew, Ferguson, Autumn, Togo, Shodai, Lewis, Kyle, Thompson, Wendy L., Asai, Akihiro, Takebe, Takanori
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2021)
Published in Gastroenterology (New York, N.Y. 1943) (01.02.2021)
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Modeling Steatohepatitis in Humans with Pluripotent Stem Cell-Derived Organoids
Ouchi, Rie, Togo, Shodai, Kimura, Masaki, Shinozawa, Tadahiro, Koido, Masaru, Koike, Hiroyuki, Thompson, Wendy, Karns, Rebekah A., Mayhew, Christopher N., McGrath, Patrick S., McCauley, Heather A., Zhang, Ran-Ran, Lewis, Kyle, Hakozaki, Shoyo, Ferguson, Autumn, Saiki, Norikazu, Yoneyama, Yosuke, Takeuchi, Ichiro, Mabuchi, Yo, Akazawa, Chihiro, Yoshikawa, Hiroshi Y., Wells, James M., Takebe, Takanori
Published in Cell metabolism (06.08.2019)
Published in Cell metabolism (06.08.2019)
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