Therapeutic immunoglobulin A antibody for dysbiosis-related diseases
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Book Review
Mice carrying a knock-in mutation of Aicda resulting in a defect in somatic hypermutation have impaired gut homeostasis and compromised mucosal defense
Honjo, Tasuku, Wei, Min, Shinkura, Reiko, Doi, Yasuko, Maruya, Mikako, Fagarasan, Sidonia
Published in Nature immunology (01.03.2011)
Published in Nature immunology (01.03.2011)
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Journal Article
MZB1 promotes the secretion of J-chain–containing dimeric IgA and is critical for the suppression of gut inflammation
Xiong, Ermeng, Li, Yingqian, Min, Qing, Cui, Chaoqun, Liu, Jun, Hong, Rongjian, Lai, Nannan, Wang, Ying, Sun, Jiping, Matsumoto, Ryohtaroh, Takahashi, Daisuke, Hase, Koji, Shinkura, Reiko, Tsubata, Takeshi, Wang, Ji-Yang
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (02.07.2019)
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Journal Article
The 49th Annual Meeting of the Japanese Society for Immunology: COVID-19 and Immunity
Shinkura, Reiko, Kang, Sujin, Arase, Hisashi, Toyama-Sorimachi, Noriko
Published in International immunology (31.03.2021)
Published in International immunology (31.03.2021)
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Journal Article
W27 IgA suppresses growth of Escherichia in an in vitro model of the human intestinal microbiota
Sasaki, Kengo, Mori, Tomoyuki, Hoshi, Namiko, Sasaki, Daisuke, Inoue, Jun, Shinkura, Reiko, Kondo, Akihiko
Published in Scientific reports (16.07.2021)
Published in Scientific reports (16.07.2021)
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Journal Article
B cell-specific and stimulation-responsive enhancers derepress Aicda by overcoming the effects of silencers
Honjo, Tasuku, Tran, Thinh Huy, Nakata, Mikiyo, Suzuki, Keiichiro, Begum, Nasim A, Shinkura, Reiko, Fagarasan, Sidonia, Nagaoka, Hitoshi
Published in Nature immunology (01.02.2010)
Published in Nature immunology (01.02.2010)
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Journal Article
High-affinity monoclonal IgA regulates gut microbiota and prevents colitis in mice
Okai, Shinsaku, Usui, Fumihito, Yokota, Shuhei, Hori-i, Yusaku, Hasegawa, Makoto, Nakamura, Toshinobu, Kurosawa, Manabu, Okada, Seiji, Yamamoto, Kazuya, Nishiyama, Eri, Mori, Hiroshi, Yamada, Takuji, Kurokawa, Ken, Matsumoto, Satoshi, Nanno, Masanobu, Naito, Tomoaki, Watanabe, Yohei, Kato, Tamotsu, Miyauchi, Eiji, Ohno, Hiroshi, Shinkura, Reiko
Published in Nature microbiology (04.07.2016)
Published in Nature microbiology (04.07.2016)
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Journal Article
Oral Corticosteroids Impair Mucin Production and Alter the Posttransplantation Microbiota in the Gut
Okafuji, Hirofumi, Iida, Noriho, Kitamura, Kazuya, Seishima, Jun, Wang, Ziyu, Yutani, Masahiro, Yoshio, Takatoshi, Yamashita, Taro, Sakai, Yoshio, Honda, Masao, Yamashita, Tatsuya, Fujinaga, Yukako, Shinkura, Reiko, Hamaguchi, Yasuhito, Mizukoshi, Eishiro, Kaneko, Shuichi
Published in Digestion (01.01.2022)
Published in Digestion (01.01.2022)
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Journal Article
Decreased Taxon-Specific IgA Response in Relation to the Changes of Gut Microbiota Composition in the Elderly
Sugahara, Hirosuke, Okai, Shinsaku, Odamaki, Toshitaka, Wong, Chyn B, Kato, Kumiko, Mitsuyama, Eri, Xiao, Jin-Zhong, Shinkura, Reiko
Published in Frontiers in microbiology (12.09.2017)
Published in Frontiers in microbiology (12.09.2017)
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Journal Article
Activation-Induced Cytidine Deaminase Shuttles between Nucleus and Cytoplasm like Apolipoprotein B mRNA Editing Catalytic Polypeptide 1
Ito, Satomi, Nagaoka, Hitoshi, Shinkura, Reiko, Begum, Nasim, Muramatsu, Masamichi, Nakata, Mikiyo, Honjo, Tasuku
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (17.02.2004)
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Journal Article
Separate domains of AID are required for somatic hypermutation and class-switch recombination
Honjo, Tasuku, Shinkura, Reiko, Ito, Satomi, Begum, Nasim A, Nagaoka, Hitoshi, Muramatsu, Masamichi, Kinoshita, Kazuo, Sakakibara, Yoshimasa, Hijikata, Hiroko
Published in Nature immunology (01.07.2004)
Published in Nature immunology (01.07.2004)
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Journal Article
Discovery of Activation‐Induced Cytidine Deaminase, the Engraver of Antibody Memory
Muramatsu, Masamichi, Nagaoka, Hitoshi, Shinkura, Reiko, Begum, Nasim A., Honjo, Tasuku
Published in AID for Immunoglobulin Diversity (2007)
Published in AID for Immunoglobulin Diversity (2007)
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Book Chapter
Journal Article
Accelerated Systemic Autoimmunity in the Absence of Somatic Hypermutation in 564Igi: A Mouse Model of Systemic Lupus with Knocked-In Heavy and Light Chain Genes
McDonald, Gabrielle, Medina, Carlos O, Pilichowska, Monika, Kearney, John F, Shinkura, Reiko, Selsing, Erik, Wortis, Henry H, Honjo, Tasuku, Imanishi-Kari, Thereza
Published in Frontiers in immunology (13.09.2017)
Published in Frontiers in immunology (13.09.2017)
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