Development of a Virtual Screening Method for Identification of “Frequent Hitters” in Compound Libraries
Roche, Olivier, Schneider, Petra, Zuegge, Jochen, Guba, Wolfgang, Kansy, Manfred, Alanine, Alexander, Bleicher, Konrad, Danel, Franck, Gutknecht, Eva-Maria, Rogers-Evans, Mark, Neidhart, Werner, Stalder, Henri, Dillon, Michael, Sjögren, Eric, Fotouhi, Nader, Gillespie, Paul, Goodnow, Robert, Harris, William, Jones, Phil, Taniguchi, Mikio, Tsujii, Shinji, von der Saal, Wolfgang, Zimmermann, Gerd, Schneider, Gisbert
Published in Journal of medicinal chemistry (03.01.2002)
Published in Journal of medicinal chemistry (03.01.2002)
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Synthesis and biological activities of benzofuran antifungal agents targeting fungal N-myristoyltransferase
Masubuchi, Miyako, Ebiike, Hirosato, Kawasaki, Ken-ichi, Sogabe, Satoshi, Morikami, Kenji, Shiratori, Yasuhiko, Tsujii, Shinji, Fujii, Toshihiko, Sakata, Kiyoaki, Hayase, Michiko, Shindoh, Hidetoshi, Aoki, Yuko, Ohtsuka, Tatsuo, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry (01.10.2003)
Published in Bioorganic & medicinal chemistry (01.10.2003)
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Journal Article
Design and synthesis of novel benzofurans as a new class of antifungal agents targeting fungal N-myristoyltransferase. Part 1
MASUBUCHI, Miyako, KAWASAKI, Ken-Ichi, OHTSUKA, Tatsuo, SHIMMA, Nobuo, EBIIKE, Hirosato, IKEDA, Yoshihiko, TSUJII, Shinji, SOGABE, Satoshi, FUJII, Toshihiko, SAKATA, Kiyoaki, SHIRATORI, Yasuhiko, AOKI, Yuko
Published in Bioorganic & medicinal chemistry letters (23.07.2001)
Published in Bioorganic & medicinal chemistry letters (23.07.2001)
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Journal Article
Formation and evaluation of mechanism-based chemical categories for regulatory read-across assessment of repeated-dose toxicity: A case of hemolytic anemia
Yamada, Takashi, Kawamura, Tomoko, Tsujii, Shinji, Miura, Minoru, Ohata, Hideo, Katsutani, Naruo, Matsumoto, Mariko, Hirose, Akihiko
Published in Regulatory toxicology and pharmacology (01.12.2022)
Published in Regulatory toxicology and pharmacology (01.12.2022)
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P-40. In silico approach that supports neurotoxicity assessment of chemical substances by IATA : Refning categories by using substructures and physicochemical and biochemical parameters related to neurotoxicity
Takashi Yamada, Shinji Tsujii, Minoru Miura, Akiko Saito, Tomoko Kawamura, Taeko Maruyama, Naruo Katsutani, Akihiko Hirose
Published in Alternatives to Animal Testing and Experimentation (31.12.2022)
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Published in Alternatives to Animal Testing and Experimentation (31.12.2022)
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Topsentin, bromotopsentin, and dihydrodeoxybromotopsentin: antiviral and antitumor bis(indolyl)imidazoles from Caribbean deep-sea sponges of the family Halichondriidae. Structural and synthetic studies
Tsujii, Shinji, Rinehart, Kenneth L, Gunasekera, Sarath P, Kashman, Yoel, Cross, Susan S, Lui, May S, Pomponi, Shirley A, Diaz, M. Cristina
Published in Journal of organic chemistry (01.11.1988)
Published in Journal of organic chemistry (01.11.1988)
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Journal Article
Design and synthesis of novel allosteric MEK inhibitor CH4987655 as an orally available anticancer agent
Isshiki, Yoshiaki, Kohchi, Yasunori, Iikura, Hitoshi, Matsubara, Yasuaki, Asoh, Kohsuke, Murata, Takeshi, Kohchi, Masami, Mizuguchi, Eisaku, Tsujii, Shinji, Hattori, Kazuo, Miura, Takaaki, Yoshimura, Yasushi, Aida, Satoshi, Miwa, Masanori, Saitoh, Ryoichi, Murao, Naoaki, Okabe, Hisafumi, Belunis, Charles, Janson, Cheryl, Lukacs, Christine, Schück, Verena, Shimma, Nobuo
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
Published in Bioorganic & medicinal chemistry letters (15.03.2011)
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Journal Article
Chemical Transformation of Terpenoids. V. Acidic Conversions of 10-Hydroxygeraniol and 10-Hydroxynerol Derivatives Leading to Cyclic Monoterpenoids
KITAGAWA, ISAO, TSUJII, SHINJI, NISHIKAWA, FUMIKO, SHIBUYA, HIROTAKA
Published in Chemical & pharmaceutical bulletin (1983)
Published in Chemical & pharmaceutical bulletin (1983)
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Chemical Transformation of Terpenoids. VI. Syntheses of Chiral Segments, Key Building-Blocks for the Left Half of Taxane-Type Diterpenoids
KITAGAWA, ISAO, TSUJII, SHINJI, FUJIOKA, HIROMICHI, KAJIWARA, AKIHARU, YAMAMOTO, YOSHIO, SHIBUYA, HIROTAKA
Published in Chemical & pharmaceutical bulletin (1984)
Published in Chemical & pharmaceutical bulletin (1984)
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Journal Article
Chemical Transformation of Terpenoids. VII. Syntheses of Chiral Segments, Key Building-Blocks for the Right Half of Taxane-Type Diterpenoids
SHIBUYA, HIROTAKA, TSUJII, SHINJI, YAMAMOTO, YOSHIO, MIURA, HIROMI, KITAGAWA, ISAO
Published in Chemical & pharmaceutical bulletin (1984)
Published in Chemical & pharmaceutical bulletin (1984)
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Chemical Transformation of Terpenoids. II. Acid Treatment of (3S)-1-Vinyl-, (3S)-1-Hydroxypropenyl-, and (3S)-1-Epoxyethyl-1, 2, 2-trimethylcyclopentane Derivatives : Ring Enlargement Reactions and Successive Migrations of Methyl Residues
KITAGAWA, ISAO, SHIBUYA, HIROTAKA, FUJIOKA, HIROMICHI, KAJIWARA, AKIHARU, YAMAMOTO, YOSHIO, TSUJII, SHINJI, MURAKAWA, KAZUYA
Published in Chemical & pharmaceutical bulletin (1981)
Published in Chemical & pharmaceutical bulletin (1981)
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Journal Article
Chemical transformation of terpenoids. I. Syntheses of (3S)-1-vinyl-, (3S)-1-hydroxypropenyl-, and (3S)-1-epoxyethyl-1,2,2-trimethylcyclopentane derivatives from d-camphor via d-camphoric acid
Kitagawa, I, Shibuya, H, Fujioka, H, Kajiwara, A, Yamamoto, Y, Tsuji, S, Takagi, A, Hori, M
Published in Chemical & pharmaceutical bulletin (1981)
Published in Chemical & pharmaceutical bulletin (1981)
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5-substituted-2-phenylamino benzamides as MEK inhibitors
ISSHIKI YOSHIAKI, IIKURA HITOSHI, MATSUBARA YASUAKI, KOHCHI MASAMI, KOHCHI YASUNORI, MURATA TAKESHI, AIDA SATOSHI, SHIMMA NOBUO, MIZUGUCHI EISAKU, MIWA MASANORI, TSUJII SHINJI, ASO KOSUKE
Year of Publication 05.11.2013
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Year of Publication 05.11.2013
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5-SUBSTITUTED-2-PHENYLAMINO-BENZAMIDE AS MEK INHIBITOR
MATSUBARA, YASUAKI, SHIMMA, NOBUO, MIWA, MASANORI, TSUJII, SHINJI, AIDA, SATOSHI, KOHCHI, YASUNORI, KOHCHI, MASAMI, MIZUGUCHI, EISAKU, ISSHIKI, YOSHIAKI, IIKURA, HITOSHI, MURATA, TAKESHI, ASO, KOSUKE
Year of Publication 26.06.2012
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Year of Publication 26.06.2012
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5-SUBSTITUTED-2-PHENYLAMINO BENZAMIDES AS MEK INHIBITORS
TAKESHI MURATA, SHINJI TSUJII, MASANORI MIWA, YASUAKI MATSUBARA, NOBUO SHIMMA, YOSHIAKI ISSHIKI, YASUNORI KOHCHI, EISAKU MIZUGUCHI, MASAMI KOHCHI, HITOSHI IIKURA, SATOSHI AIDA, KOSUKE ASO
Year of Publication 15.08.2011
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Year of Publication 15.08.2011
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5-SUBSTITUTED-2-PHENYLAMINO BENZAMIDES AS MEK INHIBITORS
MATSUBARA, YASUAKI, SHIMMA, NOBUO, MIWA, MASANORI, TSUJII, SHINJI, AIDA, SATOSHI, KOHCHI, YASUNORI, KOHCHI, MASAMI, MIZUGUCHI, EISAKU, ISSHIKI, YOSHIAKI, IIKURA, HITOSHI, MURATA, TAKESHI, ASO, KOSUKE
Year of Publication 29.04.2011
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Year of Publication 29.04.2011
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5-SUBSTITUTED-2-PHENYLAMINO BENZAMIDES AS MEK INHIBITORS
MATSUBARA, YASUAKI, SHIMMA, NOBUO, MIWA, MASANORI, TSUJII, SHINJI, AIDA, SATOSHI, KOHCHI, YASUNORI, KOHCHI, MASAMI, MIZUGUCHI, EISAKU, ISSHIKI, YOSHIAKI, IIKURA, HITOSHI, MURATA, TAKESHI, ASO, KOSUKE
Year of Publication 06.04.2011
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Year of Publication 06.04.2011
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5-SUBSTITUTED-2-PHENYLAMINO BENZAMIDES AS MEK INHIBITORS
ISSHIKI YOSHIAKI, IIKURA HITOSHI, MATSUBARA YASUAKI, KOHCHI MASAMI, KOHCHI YASUNORI, MURATA TAKESHI, AIDA SATOSHI, SHIMMA NOBUO, MIZUGUCHI EISAKU, MIWA MASANORI, TSUJII SHINJI, ASO KOSUKE
Year of Publication 28.02.2011
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Year of Publication 28.02.2011
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5-Substituerede 2-phenylamino-benzamider som MEK-inhibitorer
MATSUBARA, YASUAKI, SHIMMA, NOBUO, MIWA, MASANORI, TSUJII, SHINJI, AIDA, SATOSHI, KOHCHI, YASUNORI, KOHCHI, MASAMI, MIZUGUCHI, EISAKU, ISSHIKI, YOSHIAKI, IIKURA, HITOSHI, MURATA, TAKESHI, ASO, KOSUKE
Year of Publication 31.01.2011
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Year of Publication 31.01.2011
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5-SUBSTITUTED-2-PHENYLAMINO BENZAMIDES AS MEK INHIBITORS
TAKESHI MURATA, SHINJI TSUJII, MASANORI MIWA, YASUAKI MATSUBARA, NOBUO SHIMMA, YOSHIAKI ISSHIKI, YASUNORI KOHCHI, EISAKU MIZUGUCHI, MASAMI KOHCHI, HITOSHI IIKURA, SATOSHI AIDA, KOSUKE ASO
Year of Publication 17.12.2010
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Year of Publication 17.12.2010
Patent