Marked differences in neurochemistry and aggregates despite similar behavioural and neuropathological features of Huntington disease in the full-length BACHD and YAC128 mice
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Published in Human molecular genetics (15.05.2012)
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Glucocerebrosidase modulates cognitive and motor activities in murine models of Parkinson's disease
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Rationally designed AAV2 and AAVrh8R capsids provide improved transduction in the retina and brain
Sullivan, Jennifer A., Stanek, Lisa M., Lukason, Michael J., Bu, Jie, Osmond, Shayla R., Barry, Elizabeth A., O’Riordan, Catherine R., Shihabuddin, Lamya S., Cheng, Seng H., Scaria, Abraham
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Merits of Combination Cortical, Subcortical, and Cerebellar Injections for the Treatment of Niemann-Pick Disease Type A
Bu, Jie, Ashe, Karen M, Bringas, John, Marshall, John, Dodge, James C, Cabrera-Salazar, Mario A, Forsayeth, John, Schuchman, Edward H, Bankiewicz, Krystof S, Cheng, Seng H, Shihabuddin, Lamya S., Passini, Marco A
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Intracerebroventricular infusion of acid sphingomyelinase corrects CNS manifestations in a mouse model of Niemann–Pick A disease
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Published in Experimental neurology (01.02.2009)
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Relationship between neuropathology and disease progression in the SOD1(G93A) ALS mouse
Yang, Wendy W, Sidman, Richard L, Taksir, Tatyana V, Treleaven, Christopher M, Fidler, Jonathan A, Cheng, Seng H, Dodge, James C, Shihabuddin, Lamya S
Published in Experimental neurology (01.02.2011)
Published in Experimental neurology (01.02.2011)
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Disease progression in a mouse model of amyotrophic lateral sclerosis: the influence of chronic stress and corticosterone
Fidler, Jonathan A, Treleaven, Christopher M, Frakes, Ashley, Tamsett, Thomas J, McCrate, Mary, Cheng, Seng H, Shihabuddin, Lamya S, Kaspar, Brian K, Dodge, James C
Published in The FASEB journal (01.12.2011)
Published in The FASEB journal (01.12.2011)
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Gene Transfer to the CNS Is Efficacious in Immune-primed Mice Harboring Physiologically Relevant Titers of Anti-AAV Antibodies
Treleaven, Christopher M, Tamsett, Thomas J, Bu, Jie, Fidler, Jonathan A, Sardi, S Pablo, Hurlbut, Gregory D, Woodworth, Lisa A, Cheng, Seng H, Passini, Marco A, Shihabuddin, Lamya S, Dodge, James C
Published in Molecular therapy (01.09.2012)
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Viral alpha-synuclein knockdown prevents spreading synucleinopathy
Menon, Sindhu, Kofoed, Rikke H, Nabbouh, Fadl, Xhima, Kristiana, Al-Fahoum, Yasmeen, Langman, Tammy, Mount, Howard T J, Shihabuddin, Lamya S, Sardi, S Pablo, Fraser, Paul E, Watts, Joel C, Aubert, Isabelle, Tandon, Anurag
Published in Brain communications (2021)
Published in Brain communications (2021)
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Relationship between neuropathology and disease progression in the SOD1G93A ALS mouse
YANG, Wendy W, SIDMAN, Richard L, TAKSIR, Tatyana V, TRELEAVEN, Christopher M, FIDLER, Jonathan A, CHENG, Seng H, DODGE, James C, SHIHABUDDIN, Lamya S
Published in Experimental neurology (01.02.2011)
Published in Experimental neurology (01.02.2011)
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Intracranial Delivery of CLN2 Reduces Brain Pathology in a Mouse Model of Classical Late Infantile Neuronal Ceroid Lipofuscinosis
Passini, Marco A, Dodge, James C, Bu, Jie, Yang, Wendy, Zhao, Qi, Sondhi, Dolan, Hackett, Neil R, Kaminsky, Stephen M, Mao, Qinwen, Shihabuddin, Lamya S, Cheng, Seng H, Sleat, David E, Stewart, Gregory R, Davidson, Beverly L, Lobel, Peter, Crystal, Ronald G
Published in The Journal of neuroscience (01.02.2006)
Published in The Journal of neuroscience (01.02.2006)
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Timing of Therapeutic Intervention Determines Functional and Survival Outcomes in a Mouse Model of Late Infantile Batten Disease
Cabrera-Salazar, Mario A, Roskelley, Eric M, Bu, Jie, Hodges, Bradley L, Yew, Nelson, Dodge, James C, Shihabuddin, Lamya S, Sohar, Istvan, Sleat, David E, Scheule, Ronald K, Davidson, Beverly L, Cheng, Seng H, Lobel, Peter, Passini, Marco A
Published in Molecular therapy (01.10.2007)
Published in Molecular therapy (01.10.2007)
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Antisense oligonucleotide-mediated correction of transcriptional dysregulation is correlated with behavioral benefits in the YAC128 mouse model of Huntington's disease
Stanek, Lisa M, Yang, Wendy, Angus, Stuart, Sardi, Pablo S, Hayden, Michael R, Hung, Gene H, Bennett, C Frank, Cheng, Seng H, Shihabuddin, Lamya S
Published in Journal of Huntington's disease (2013)
Published in Journal of Huntington's disease (2013)
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Anti-murine CD52 antibody treatment does not adversely affect the migratory ability of immune cells
Havari, Evis, Turner, Michael J, Dodge, James C, Treleaven, Christopher, Shihabuddin, Lamya S, Roberts, Bruce L, Kaplan, Johanne M, Siders, William M
Published in Journal of neuroimmunology (01.01.2014)
Published in Journal of neuroimmunology (01.01.2014)
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Ability of adeno-associated virus serotype 8-mediated hepatic expression of acid alpha-glucosidase to correct the biochemical and motor function deficits of presymptomatic and symptomatic Pompe mice
Ziegler, Robin J, Bercury, Scott D, Fidler, Jonathan, Zhao, Michael A, Foley, Joseph, Taksir, Tatyana V, Ryan, Susan, Hodges, Bradley L, Scheule, Ronald K, Shihabuddin, Lamya S, Cheng, Seng H
Published in Human gene therapy (01.06.2008)
Published in Human gene therapy (01.06.2008)
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AAV Vector-Mediated Correction of Brain Pathology in a Mouse Model of Niemann–Pick A Disease
Passini, Marco A., Macauley, Shannon L., Huff, Michael R., Taksir, Tatyana V., Bu, Jie, Wu, I-Huan, Piepenhagen, Peter A., Dodge, James C., Shihabuddin, Lamya S., O'Riordan, Catherine R., Schuchman, Edward H., Stewart, Gregory R.
Published in Molecular therapy (01.05.2005)
Published in Molecular therapy (01.05.2005)
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Injection of mouse and human neural stem cells into neonatal Niemann–Pick A model mice
Sidman, Richard L, Li, Jianxue, Stewart, Greg R, Clarke, Jennifer, Yang, Wendy, Snyder, Evan Y, Shihabuddin, Lamya S
Published in Brain research (06.04.2007)
Published in Brain research (06.04.2007)
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FGF-2 Is Sufficient to Isolate Progenitors Found in the Adult Mammalian Spinal Cord
Shihabuddin, Lamya S., Ray, Jasodhara, Gage, Fred H.
Published in Experimental neurology (01.12.1997)
Published in Experimental neurology (01.12.1997)
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Optimized Preservation of CNS Morphology for the Identification of Glycogen in the Pompe Mouse Model
Taksir, Tatyana V, Griffiths, Denise, Johnson, Jennifer, Ryan, Susan, Shihabuddin, Lamya S, Thurberg, Beth L
Published in The journal of histochemistry and cytochemistry (01.10.2007)
Published in The journal of histochemistry and cytochemistry (01.10.2007)
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