Human Immunodeficiency Virus Type 1 Mutants Resistant to Nonnucleoside Inhibitors of Reverse Transcriptase Arise in Tissue Culture
Richman, D, Shih, C K, Lowy, I, Rose, J, Prodanovich, P, Goff, S, Griffin, J
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.1991)
Published in Proceedings of the National Academy of Sciences - PNAS (15.12.1991)
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Inhibition of HIV-1 Replication by a Nonnucleoside Reverse Transcriptase Inhibitor
Merluzzi, Vincent J., Hargrave, Karl D., Labadia, Mark, Grozinger, Karl, Skoog, Mark, Wu, Joseph C., Shih, Cheng-Kon, Eckner, Kristine, Hattox, Susan, Adams, Julian, Rosehthal, Alan S., Faanes, Ronald, Eckner, Robert J., Koup, Richard A., Sullivan, John L.
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Published in Science (American Association for the Advancement of Science) (07.12.1990)
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Discovery of Imigliptin, a Novel Selective DPP‑4 Inhibitor for the Treatment of Type 2 Diabetes
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Published in ACS medicinal chemistry letters (14.08.2014)
Published in ACS medicinal chemistry letters (14.08.2014)
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Trifluoromethyl group as a pharmacophore: Effect of replacing a CF 3 group on binding and agonist activity of a glucocorticoid receptor ligand
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Published in Bioorganic & medicinal chemistry letters (01.11.2005)
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
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Trifluoromethyl group as a pharmacophore : Effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand
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Published in Bioorganic & medicinal chemistry letters (01.11.2005)
Published in Bioorganic & medicinal chemistry letters (01.11.2005)
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Identification of dissociated non-steroidal glucocorticoid receptor agonists
Kuzmich, Daniel, Kirrane, Tom, Proudfoot, John, Bekkali, Younes, Zindell, Renee, Beck, Laura, Nelson, Richard, Shih, Cheng-Kon, Kukulka, Alison J., Paw, Zofia, Reilly, Patty, Deleon, Rodney, Cardozo, Mario, Nabozny, Gerald, Thomson, David
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
Published in Bioorganic & medicinal chemistry letters (15.09.2007)
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Chimeric Human Immunodeficiency Virus Type 1/Type 2 Reverse Transcriptases Display Reversed Sensitivity to Nonnucleoside Analog Inhibitors
Shih, Cheng-Kon, Rose, Janice M., Hansen, Gale L., Wu, Joe C., Bacolla, Albino, Griffin, Johanna A.
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1991)
Published in Proceedings of the National Academy of Sciences - PNAS (01.11.1991)
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Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account
Wu, Frank, Büttner, Frank H., Chen, Rhonda, Hickey, Eugene, Jakes, Scott, Kaplita, Paul, Kashem, Mohammed A., Kerr, Steven, Kugler, Stanley, Paw, Zofia, Prokopowicz, Anthony, Shih, Cheng-Kon, Snow, Roger, Young, Erick, Cywin, Charles L.
Published in Bioorganic & medicinal chemistry letters (01.06.2010)
Published in Bioorganic & medicinal chemistry letters (01.06.2010)
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Hit to Lead Account of the Discovery of Bisbenzamide and Related Ureidobenzamide Inhibitors of Rho Kinase
Morwick, Tina, Büttner, Frank H, Cywin, Charles L, Dahmann, Georg, Hickey, Eugene, Jakes, Scott, Kaplita, Paul, Kashem, Mohammed A, Kerr, Steven, Kugler, Stanley, Mao, Wang, Marshall, Daniel, Paw, Zofia, Shih, Cheng-Kon, Wu, Frank, Young, Erick
Published in Journal of medicinal chemistry (28.01.2010)
Published in Journal of medicinal chemistry (28.01.2010)
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Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy
Richman, D D, Havlir, D, Corbeil, J, Looney, D, Ignacio, C, Spector, S A, Sullivan, J, Cheeseman, S, Barringer, K, Pauletti, D
Published in Journal of Virology (01.03.1994)
Published in Journal of Virology (01.03.1994)
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Nonnucleoside inhibitors of HIV-1 reverse transcriptase: nevirapine as a prototype drug
Grob, P M, Wu, J C, Cohen, K A, Ingraham, R H, Shih, C K, Hargrave, K D, McTague, T L, Merluzzi, V J
Published in AIDS research and human retroviruses (01.02.1992)
Published in AIDS research and human retroviruses (01.02.1992)
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Steady state kinetics and inhibition of HIV-1 reverse transcriptase by a non-nucleoside dipyridodiazepinone, BI-RG-587, using a heteropolymeric template
KOPP, E. B, MIGLIETTA, J. J, SHRUTKOWSKI, A. G, CHENG-KON SHIH, GROB, P. M, SKOOG, M. T
Published in Nucleic acids research (11.06.1991)
Published in Nucleic acids research (11.06.1991)
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Prophylaxis against HIV-1 infection in chimpanzees by nevirapine, a nonnucleoside inhibitor of reverse transcriptase
Grob, P M, Cao, Y, Muchmore, E, Ho, D D, Norris, S, Pav, J W, Shih, C K, Adams, J
Published in Nature medicine (01.06.1997)
Published in Nature medicine (01.06.1997)
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Novel Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase. 7. 8-Arylethyldipyridodiazepinones as Potent Broad-Spectrum Inhibitors of Wild-Type and Mutant Enzymes
Klunder, Janice M, Hoermann, MaryAnn, Cywin, Charles L, David, Eva, Brickwood, Janice R, Schwartz, Racheline, Barringer, Kevin J, Pauletti, Daniel, Shih, Cheng-Kon, Erickson, David A, Sorge, Christopher L, Joseph, David P, Hattox, Susan E, Adams, Julian, Grob, Peter M
Published in Journal of medicinal chemistry (30.07.1998)
Published in Journal of medicinal chemistry (30.07.1998)
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Novel Nonnucleoside Inhibitors of HIV-1 Reverse Transcriptase. 8. 8-Aryloxymethyl- and 8-Arylthiomethyldipyridodiazepinones
Cywin, Charles L, Klunder, Janice M, Hoermann, MaryAnn, Brickwood, Janice R, David, Eva, Grob, Peter M, Schwartz, Racheline, Pauletti, Daniel, Barringer, Kevin J, Shih, Cheng-Kon, Sorge, Christopher L, Erickson, David A, Joseph, David P, Hattox, Susan E
Published in Journal of medicinal chemistry (30.07.1998)
Published in Journal of medicinal chemistry (30.07.1998)
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Expression of reverse transcriptase from feline immunodeficiency virus in Escherichia coli
North, T W, Hansen, G L, Zhu, Y, Griffin, J A, Shih, C K
Published in Antimicrobial Agents and Chemotherapy (01.02.1994)
Published in Antimicrobial Agents and Chemotherapy (01.02.1994)
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Nucleotide Sequence 5′of the Chicken c-myc Coding Region: Localization of a Noncoding Exon That is Absent from myc Transcripts in Most Avian Leukosis Virus-Induced Lymphomas
Shih, Cheng-Kon, Linial, Maxine, Goodenow, Maureen M., Hayward, William S.
Published in Proceedings of the National Academy of Sciences - PNAS (01.08.1984)
Published in Proceedings of the National Academy of Sciences - PNAS (01.08.1984)
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Novel Non-Nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 Reverse Transcriptase. 6. 2-Indol-3-yl- and 2-Azaindol-3-yl- dipyridodiazepinones
Kelly, Terence A, McNeil, Daniel W, Rose, Janice M, David, Eva, Shih, Cheng-Kon, Grob, Peter M
Published in Journal of medicinal chemistry (18.07.1997)
Published in Journal of medicinal chemistry (18.07.1997)
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Novel Non-nucleoside Inhibitors of Human Immunodeficiency Virus Type 1 (HIV-1) Reverse Transcriptase. 4. 2-Substituted Dipyridodiazepinones as Potent Inhibitors of Both Wild-Type and Cysteine-181 HIV-1 Reverse Transcriptase Enzymes
Proudfoot, John R, Hargrave, Karl D, Kapadia, Suresh R, Patel, Usha R, Grozinger, Karl G, McNeil, Daniel W, Cullen, Ernest, Cardozo, Mario, Tong, Liang
Published in Journal of medicinal chemistry (01.11.1995)
Published in Journal of medicinal chemistry (01.11.1995)
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