Discovery of 2,4-diamino-5-cyanopyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug-drug interactions
Kunikawa, Shigeki, Tanaka, Akira, Takasuna, Yuji, Tasaki, Mamoru, Chida, Noboru
Published in Bioorganic & medicinal chemistry (01.03.2019)
Published in Bioorganic & medicinal chemistry (01.03.2019)
Get full text
Journal Article
A novel 2,4-diaminopyrimidine derivative as selective inhibitor of protein kinase C theta prevents allograft rejection in a rat heart transplant model
Kunikawa, Shigeki, Tanaka, Akira, Takasuna, Yuji, Tasaki, Mamoru, Chida, Noboru
Published in Bioorganic & medicinal chemistry (01.11.2018)
Published in Bioorganic & medicinal chemistry (01.11.2018)
Get full text
Journal Article
Optimization of 2,4-diamino-5-fluoropyrimidine derivatives as protein kinase C theta inhibitors with mitigated time-dependent drug–drug interactions and P-gp liability
Kunikawa, Shigeki, Tanaka, Akira, Mukoyoshi, Koichiro, Nagashima, Shinya, Tominaga, Hiroaki, Chida, Noboru, Tasaki, Mamoru, Shirai, Fumiyuki
Published in Bioorganic & medicinal chemistry (01.07.2015)
Published in Bioorganic & medicinal chemistry (01.07.2015)
Get full text
Journal Article
Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3
Nakajima, Yutaka, Inoue, Takayuki, Nakai, Kazuo, Mukoyoshi, Koichiro, Hamaguchi, Hisao, Hatanaka, Keiko, Sasaki, Hiroshi, Tanaka, Akira, Takahashi, Fumie, Kunikawa, Shigeki, Usuda, Hiroyuki, Moritomo, Ayako, Higashi, Yasuyuki, Inami, Masamichi, Shirakami, Shohei
Published in Bioorganic & medicinal chemistry (01.08.2015)
Published in Bioorganic & medicinal chemistry (01.08.2015)
Get full text
Journal Article
Corrigendum to “Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3” [Bioorg. Med. Chem. 23 (2015) 4871–4883]
Nakajima, Yutaka, Inoue, Takayuki, Nakai, Kazuo, Mukoyoshi, Koichiro, Hamaguchi, Hisao, Hatanaka, Keiko, Sasaki, Hiroshi, Tanaka, Akira, Takahashi, Fumie, Kunikawa, Shigeki, Usuda, Hiroyuki, Moritomo, Ayako, Higashi, Yasuyuki, Inami, Masamichi, Shirakami, Shohei
Published in Bioorganic & medicinal chemistry (15.05.2017)
Published in Bioorganic & medicinal chemistry (15.05.2017)
Get full text
Journal Article
Corrigendum to “Synthesis and evaluation of novel 1H-pyrrolo[2,3-b]pyridine-5-carboxamide derivatives as potent and orally efficacious immunomodulators targeting JAK3” [Bioorg. Med. Chem. 23 (2015) 4871–4883]
Nakajima, Yutaka, Inoue, Takayuki, Nakai, Kazuo, Mukoyoshi, Koichiro, Hamaguchi, Hisao, Hatanaka, Keiko, Sasaki, Hiroshi, Tanaka, Akira, Takahashi, Fumie, Kunikawa, Shigeki, Usuda, Hiroyuki, Moritomo, Ayako, Higashi, Yasuyuki, Inami, Masamichi, Shirakami, Shohei
Published in Bioorganic & medicinal chemistry (15.09.2016)
Published in Bioorganic & medicinal chemistry (15.09.2016)
Get full text
Journal Article
Synthesis of Antimalarial Yingzhaosu A Analogues by the Peroxidation of Dienes with Co(II)/O2/Et3SiH
Tokuyasu, Takahiro, Kunikawa, Shigeki, Abe, Manabu, Masuyama, Araki, Nojima, Masatomo, Kim, Hye-Sook, Begum, Khurshida, Wataya, Yusuke
Published in Journal of organic chemistry (19.09.2003)
Published in Journal of organic chemistry (19.09.2003)
Get full text
Journal Article
Co-catalyzed autoxidation of alkene in the presence of silane. The effect of the structure of silanes on the efficiency of the reaction and on the product distribution
Wu, Jin-Ming, Kunikawa, Shigeki, Tokuyasu, Takahiro, Masuyama, Araki, Nojima, Masatomo, Kim, Hye-Sook, Wataya, Yusuke
Published in Tetrahedron (17.10.2005)
Published in Tetrahedron (17.10.2005)
Get full text
Journal Article
IMIDAZODIAZEPINE COMPOUND
MASUDA, NAOYUKI, YARIMIZU, JUNKO, KUNIKAWA, SHIGEKI, MORITA, MASATAKA, KAWAKAMI, SHIMPEI, IMAIZUMI, TOMOYOSHI
Year of Publication 15.08.2023
Get full text
Year of Publication 15.08.2023
Patent
IMIDAZODIAZEPINE COMPOUND
MASATAKA MORITA, SHIMPEI KAWAKAMI, SHIGEKI KUNIKAWA, JUNKO YARIMIZU, TOMOYOSHI IMAIZUMI, NAOYUKI MASUDA
Year of Publication 19.06.2023
Get full text
Year of Publication 19.06.2023
Patent
Synthesis of Antimalarial Yingzhaosu A Analogues by the Peroxidation of Dienes with Co(II)/O 2 /Et 3 SiH
Tokuyasu, Takahiro, Kunikawa, Shigeki, Abe, Manabu, Masuyama, Araki, Nojima, Masatomo, Kim, Hye-Sook, Begum, Khurshida, Wataya, Yusuke
Published in Journal of organic chemistry (01.09.2003)
Published in Journal of organic chemistry (01.09.2003)
Get full text
Journal Article
TETRAHYDROOXEPINOPYRIDINE COMPOUND
SATO, RYO, KUNIKAWA, SHIGEKI, KOGANEMARU, YOHEI, KAMIKAWA, AKIO, MIYAMOTO, SATOSHI, AOKI, SATOSHI, KOIZUMI, YUKA, TAMAKI, KEISUKE, SHISHIKURA, JUNICHI, OGIYAMA, TAKASHI, KAWAKAMI, SHIMPEI, KAKIMOTO, SHUICHIROU, YAMADA, HIROSHI, NAGASHIMA, SHINYA, YONEZAWA, KOICHI
Year of Publication 27.06.2023
Get full text
Year of Publication 27.06.2023
Patent
IMIDAZODIAZEPINE COMPOUND
KAWAKAMI, Shimpei, MORITA, Masataka, IMAIZUMI, Tomoyoshi, MASUDA, Naoyuki, KUNIKAWA, Shigeki, YARIMIZU, Junko
Year of Publication 28.04.2020
Get full text
Year of Publication 28.04.2020
Patent
QUINAZOLINE COMPOUND
WATANABE, KAZUSHI, NIGAWARA, TAKAHIRO, KUNIKAWA, SHIGEKI, ARAKAWA, KEISUKE, SHIMADA, ITSURO, IMAIZUMI, TOMOYOSHI, SATAKE, YOSHIKI, YAMAKI, SUSUMU, ARAKI, TAKANOBU, SHIMAZAKI, MASASHI, KOIKE, TAKANORI, KURAMOTO, KAZUYUKI, AKAIWA, MICHINORI, ABE, TOMOAKI
Year of Publication 17.01.2022
Get full text
Year of Publication 17.01.2022
Patent
IMIDAZODIAZEPINE COMPOUND
IMAIZUMI Tomoyoshi, KUNIKAWA Shigeki, YARIMIZU Junko, KAWAKAMI Shimpei, MORITA Masataka, MASUDA Naoyuki
Year of Publication 28.02.2020
Get full text
Year of Publication 28.02.2020
Patent
IMIDAZODIAZEPINE COMPOUND
Kunikawa, Shigeki, Yarimizu, Junko, Morita, Masataka, Kawakami, Shimpei, Masuda, Naoyuki, Imaizumi, Tomoyoshi
Year of Publication 07.02.2020
Get full text
Year of Publication 07.02.2020
Patent