A high number of PD-L1+ CD14+ monocytes in peripheral blood is correlated with shorter survival in patients receiving immune checkpoint inhibitors
Ando, Kiyohiro, Hamada, Kazuyuki, Shida, Midori, Ohkuma, Ryotaro, Kubota, Yutaro, Horiike, Atsushi, Matsui, Hiroto, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Watanabe, Makoto, Onoue, Rie, Tsurutani, Junji, Yoshimura, Kiyoshi, Tsunoda, Takuya, Kobayashi, Shinichi, Wada, Satoshi
Published in Cancer Immunology, Immunotherapy (01.02.2021)
Published in Cancer Immunology, Immunotherapy (01.02.2021)
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Antibiotic Usage Reduced Overall Survival by over 70% in Non-small Cell Lung Cancer Patients on Anti-PD-1 Immunotherapy
HAMADA, KAZUYUKI, YOSHIMURA, KIYOSHI, HIRASAWA, YUYA, HOSONUMA, MASAHIRO, MURAYAMA, MASAKAZU, NARIKAWA, YOICHIRO, ARIIZUMI, HIROTSUGU, OHKUMA, RYOTARO, SHIDA, MIDORI, KUBOTA, YUTARO, MATSUKUMA, SATOSHI, ISHIGURO, TOMOYUKI, SAMBE, TAKEHIKO, HORIIKE, ATSUSHI, KURAMASU, ATSUO, WADA, SATOSHI, TSURUTANI, JUNJI, INOUE, EISUKE, UCHIDA, NAOKI, KIUCHI, YUJI, KOBAYASHI, SHINICHI, HOFFMAN, ROBERT M., TSUNODA, TAKUYA
Published in Anticancer research (01.10.2021)
Published in Anticancer research (01.10.2021)
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Journal Article
Turicibacter and Acidaminococcus predict immune-related adverse events and efficacy of immune checkpoint inhibitor
Hamada, Kazuyuki, Isobe, Junya, Hattori, Kouya, Hosonuma, Masahiro, Baba, Yuta, Murayama, Masakazu, Narikawa, Yoichiro, Toyoda, Hitoshi, Funayama, Eiji, Tajima, Kohei, Shida, Midori, Hirasawa, Yuya, Tsurui, Toshiaki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Risako, Ohkuma, Ryotaro, Kubota, Yutaro, Sambe, Takehiko, Tsuji, Mayumi, Wada, Satoshi, Kiuchi, Yuji, Kobayashi, Shinichi, Kuramasu, Atsuo, Horiike, Atsushi, Kim, Yun-Gi, Tsunoda, Takuya, Yoshimura, Kiyoshi
Published in Frontiers in immunology (03.05.2023)
Published in Frontiers in immunology (03.05.2023)
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Journal Article
MHC class I polypeptide-related sequence B shedding modulates pancreatic tumor immunity via the activation of NKG2DLow T cells
Toyoda, Hitoshi, Kuramasu, Atsuo, Hosonuma, Masahiro, Murayama, Masakazu, Narikawa, Yoichiro, Isobe, Junya, Baba, Yuta, Tajima, Kohei, Funayama, Eiji, Shida, Midori, Maruyama, Yuki, Sasaki, Aya, Hirasawa, Yuya, Tsurui, Toshiaki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Risako, Kobayashi, Sei, Horiike, Atsushi, Hida, Noriko, Sambe, Takehiko, Nobe, Koji, Wada, Satoshi, Kobayashi, Hitome, Tsuji, Mayumi, Kobayashi, Shinichi, Tsunoda, Takuya, Kudo, Yoshifumi, Kiuchi, Yuji, Yoshimura, Kiyoshi
Published in Scientific reports (08.10.2024)
Published in Scientific reports (08.10.2024)
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Journal Article
Isobutyric acid enhances the anti-tumour effect of anti-PD-1 antibody
Murayama, Masakazu, Hosonuma, Masahiro, Kuramasu, Atsuo, Kobayashi, Sei, Sasaki, Akiko, Baba, Yuta, Narikawa, Yoichiro, Toyoda, Hitoshi, Isobe, Junya, Funayama, Eiji, Tajima, Kohei, Sasaki, Aya, Maruyama, Yuki, Yamazaki, Yoshitaka, Shida, Midori, Hamada, Kazuyuki, Hirasawa, Yuya, Tsurui, Toshiaki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Risako, Ohkuma, Ryotaro, Kubota, Yutaro, Horiike, Atsushi, Sambe, Takehiko, Tsuji, Mayumi, Wada, Satoshi, Kobayashi, Shinichi, Shimane, Toshikazu, Tsunoda, Takuya, Kobayashi, Hitome, Kiuchi, Yuji, Yoshimura, Kiyoshi
Published in Scientific reports (17.05.2024)
Published in Scientific reports (17.05.2024)
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A case report on severe nivolumab-induced adverse events similar to primary sclerosing cholangitis refractory to immunosuppressive therapy
Hirasawa, Yuya, Yoshimura, Kiyoshi, Matsui, Hiroto, Kubota, Yutaro, Ishida, Hiroo, Arai, Jun, Sakaki, Masashi, Oguro, Nao, Shida, Midori, Taniguchi, Makoto, Hamada, Kazuyuki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Ohkuma, Ryotaro, Sambe, Takehiko, Horiike, Atsushi, Imamura, Chiyo K, Shiozawa, Eisuke, Wada, Satoshi, Tsurutani, Junji, Iwamoto, Sanju, Uchida, Naoki, Kiuchi, Yuji, Tate, Genshu, Kobayashi, Shinichi, Tsunoda, Takuya
Published in Medicine (Baltimore) (11.06.2021)
Published in Medicine (Baltimore) (11.06.2021)
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Journal Article
High expression of olfactomedin-4 is correlated with chemoresistance and poor prognosis in pancreatic cancer
Ohkuma, Ryotaro, Yada, Erica, Ishikawa, Shumpei, Komura, Daisuke, Ishizaki, Hidenobu, Tamada, Koji, Kubota, Yutaro, Hamada, Kazuyuki, Ishida, Hiroo, Hirasawa, Yuya, Ariizumi, Hirotsugu, Satoh, Etsuko, Shida, Midori, Watanabe, Makoto, Onoue, Rie, Ando, Kiyohiro, Tsurutani, Junji, Yoshimura, Kiyoshi, Yokobori, Takehiko, Sasada, Tetsuro, Aoki, Takeshi, Murakami, Masahiko, Norose, Tomoko, Ohike, Nobuyuki, Takimoto, Masafumi, Izumizaki, Masahiko, Kobayashi, Shinichi, Tsunoda, Takuya, Wada, Satoshi
Published in PloS one (01.01.2020)
Published in PloS one (01.01.2020)
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Journal Article
Plasma Levels of Soluble PD-L1 Correlate With Tumor Regression in Patients With Lung and Gastric Cancer Treated With Immune Checkpoint Inhibitors
Ando, Kiyohiro, Hamada, Kazuyuki, Watanabe, Makoto, Ohkuma, Ryotaro, Shida, Midori, Onoue, Rie, Kubota, Yutaro, Matsui, Hiroto, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Tsurutani, Junji, Yoshimura, Kiyoshi, Tsunoda, Takuya, Kobayashi, Shinichi, Wada, Satoshi
Published in Anticancer research (01.09.2019)
Published in Anticancer research (01.09.2019)
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Journal Article
A case of bronchial asthma as an immune-related adverse event of pembrolizumab treatment for bladder cancer: A case report
Hamada, Kazuyuki, Yoshimura, Kiyoshi, Oshinomi, Kazuhiko, Hirasawa, Yuya, Ariizumi, Hirotsugu, Ohkuma, Ryotaro, Shida, Midori, Kubota, Yutaro, Matsui, Hiroto, Ishiguro, Tomoyuki, Sambe, Takehiko, Ishida, Hiroo, Horiike, Atsushi, Wada, Satoshi, Iwamoto, Sanju, Uchida, Naoki, Ogawa, Yoshio, Kobayashi, Shinichi, Tsunoda, Takuya
Published in Medicine (Baltimore) (14.01.2022)
Published in Medicine (Baltimore) (14.01.2022)
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Journal Article
Nivolumab receptor occupancy on effector regulatory T cells predicts clinical benefit
Hosonuma, Masahiro, Hirasawa, Yuya, Kuramasu, Atsuo, Murayama, Masakazu, Narikawa, Yoichiro, Toyoda, Hitoshi, Baba, Yuta, Isobe, Junya, Funayama, Eiji, Tajima, Kohei, Shida, Midori, Hamada, Kazuyuki, Tsurui, Toshiaki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Risako, Ohkuma, Ryotaro, Kubota, Yutaro, Horiike, Atsushi, Sambe, Takehiko, Tsuji, Mayumi, Wada, Satoshi, Kiuchi, Yuji, Kobayashi, Shinichi, Tsunoda, Takuya, Yoshimura, Kiyoshi
Published in Cancer science (01.03.2024)
Published in Cancer science (01.03.2024)
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Journal Article
NKG2D-high T cells are able to be activated regardless of the level of NKG2D ligands expression
Toyoda, Hitoshi, Hosonuma, Masahiro, Kuramasu, Atsuo, Narikawa, Youichirou, Murayama, Masakazu, Isobe, Junya, Shida, Midori, Sambe, Takehiko, Tsuji, Mayumi, Tsunoda, Takuya, Kobayashi, Shinichi, Inagaki, Katsunori, Kiuchi, Yuji, Yoshimura, Kiyoshi
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2022)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2022)
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Journal Article
Gut microbiota associate with recurrence of cancer after surgery in colorectal cancer patients
Junya, Isobe, Hosonuma, Masahiro, Kuramasu, Atsuo, Narikawa, Yoichiro, Murayama, Masakazu, Shida, Midori, Sambe, Takehiko, Tsuji, Mayumi, Tsunoda, Takuya, Kobayashi, Shinichi, Kiuchi, Yuji, Yoshimura, Kiyoshi
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2022)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2022)
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Establishment for big data base of Microbiota closely related to diseases - Showa U bank
Tsunoda, Takuya, Shimada, Kazunori, Shida, Midori, Ryu, Kakei, Namba, Hokuto, Sambe, Tekehiko, Hida, Noriko, Uchida, Naoki, Kobayashi, Shinichi
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
Published in Proceedings for Annual Meeting of The Japanese Pharmacological Society (2018)
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Journal Article
Butyricimonas is a key gut microbiome component for predicting postoperative recurrence of esophageal cancer
Otsuka, Koji, Isobe, Junya, Asai, Yoshiyuki, Nakano, Tomohisa, Hattori, Kouya, Ariyoshi, Tomotake, Yamashita, Takeshi, Motegi, Kentaro, Saito, Akira, Kohmoto, Masahiro, Hosonuma, Masahiro, Kuramasu, Atsuo, Baba, Yuta, Murayama, Masakazu, Narikawa, Yoichiro, Toyoda, Hitoshi, Funayama, Eiji, Tajima, Kohei, Shida, Midori, Hirasawa, Yuya, Tsurui, Toshiaki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Risako, Ohkuma, Ryotaro, Kubota, Yutaro, Sambe, Takehiko, Tsuji, Mayumi, Wada, Satoshi, Kiuchi, Yuji, Kobayashi, Shinichi, Horiike, Atsushi, Goto, Satoru, Murakami, Masahiko, Kim, Yun-Gi, Tsunoda, Takuya, Yoshimura, Kiyoshi
Published in Cancer Immunology, Immunotherapy (27.01.2024)
Published in Cancer Immunology, Immunotherapy (27.01.2024)
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Journal Article
High levels of human epididymis protein 4 mRNA and protein expression are associated with chemoresistance and a poor prognosis in pancreatic cancer
Ohkuma, Ryotaro, Yada, Erica, Ishikawa, Shumpei, Komura, Daisuke, Kubota, Yutaro, Hamada, Kazuyuki, Horiike, Atsushi, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Shida, Midori, Watanabe, Makoto, Onoue, Rie, Ando, Kiyohiro, Tsurutani, Junji, Yoshimura, Kiyoshi, Sasada, Tetsuro, Aoki, Takeshi, Murakami, Masahiko, Norose, Tomoko, Ohike, Nobuyuki, Takimoto, Masafumi, Kobayashi, Shinichi, Tsunoda, Takuya, Wada, Satoshi
Published in International journal of oncology (01.01.2021)
Published in International journal of oncology (01.01.2021)
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Journal Article
High expression levels of polymeric immunoglobulin receptor are correlated with chemoresistance and poor prognosis in pancreatic cancer
Ohkuma, Ryotaro, Yada, Erica, Ishikawa, Shumpei, Komura, Daisuke, Kubota, Yutaro, Hamada, Kazuyuki, Horiike, Atsushi, Ishiguro, Tomoyuki, Hirasawa, Yuya, Ariizumi, Hirotsugu, Shida, Midori, Watanabe, Makoto, Onoue, Rie, Ando, Kiyohiro, Tsurutani, Junji, Yoshimura, Kiyoshi, Sasada, Tetsuro, Aoki, Takeshi, Murakami, Masahiko, Norose, Tomoko, Ohike, Nobuyuki, Takimoto, Masafumi, Kobayashi, Shinichi, Tsunoda, Takuya, Wada, Satoshi
Published in Oncology reports (01.07.2020)
Published in Oncology reports (01.07.2020)
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Journal Article
Rare Nivolumab-associated Super Hyper Progressive Disease in Patients With Advanced Gastric Cancer
Kubota, Yutaro, Yoshimura, Kiyoshi, Hamada, Kazuyuki, Hirasawa, Yuya, Shida, Midori, Taniguchi, Makoto, Matsui, Hiroto, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Norihiro, Ohkuma, Ryotaro, Sambe, Takehiko, Ishida, Hiroo, Horiike, Atsushi, Wada, Satoshi, Tsurutani, Junji, Iwamoto, Sanju, Uchida, Naoki, Kiuchi, Yuji, Kobayashi, Shinichi, Tsunoda, Takuya
Published in In vivo (Athens) (01.05.2021)
Published in In vivo (Athens) (01.05.2021)
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Journal Article
MHC class I polypeptide-related sequence B shedding modulates pancreatic tumor immunity via the activation of NKG2D Low T cells
Toyoda, Hitoshi, Kuramasu, Atsuo, Hosonuma, Masahiro, Murayama, Masakazu, Narikawa, Yoichiro, Isobe, Junya, Baba, Yuta, Tajima, Kohei, Funayama, Eiji, Shida, Midori, Maruyama, Yuki, Sasaki, Aya, Hirasawa, Yuya, Tsurui, Toshiaki, Ariizumi, Hirotsugu, Ishiguro, Tomoyuki, Suzuki, Risako, Kobayashi, Sei, Horiike, Atsushi, Hida, Noriko, Sambe, Takehiko, Nobe, Koji, Wada, Satoshi, Kobayashi, Hitome, Tsuji, Mayumi, Kobayashi, Shinichi, Tsunoda, Takuya, Kudo, Yoshifumi, Kiuchi, Yuji, Yoshimura, Kiyoshi
Published in Scientific reports (08.10.2024)
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Published in Scientific reports (08.10.2024)
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