Nucleic acid-sensing TLRs and autoimmunity: novel insights from structural and cell biology
Pelka, Karin, Shibata, Takuma, Miyake, Kensuke, Latz, Eicke
Published in Immunological reviews (01.01.2016)
Published in Immunological reviews (01.01.2016)
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Crystal structure of NOD2 and its implications in human disease
Maekawa, Sakiko, Ohto, Umeharu, Shibata, Takuma, Miyake, Kensuke, Shimizu, Toshiyuki
Published in Nature communications (10.06.2016)
Published in Nature communications (10.06.2016)
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Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Ohto, Umeharu, Shibata, Takuma, Tanji, Hiromi, Ishida, Hanako, Krayukhina, Elena, Uchiyama, Susumu, Miyake, Kensuke, Shimizu, Toshiyuki
Published in Nature (London) (30.04.2015)
Published in Nature (London) (30.04.2015)
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Mechanisms controlling nucleic acid-sensing Toll-like receptors
Miyake, Kensuke, Shibata, Takuma, Ohto, Umeharu, Shimizu, Toshiyuki, Saitoh, Shin-Ichiroh, Fukui, Ryutaro, Murakami, Yusuke
Published in International immunology (08.03.2018)
Published in International immunology (08.03.2018)
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Guanosine and its modified derivatives are endogenous ligands for TLR7
Shibata, Takuma, Ohto, Umeharu, Nomura, Shosaku, Kibata, Kayoko, Motoi, Yuji, Zhang, Yan, Murakami, Yusuke, Fukui, Ryutaro, Ishimoto, Tatsushi, Sano, Shigetoshi, Ito, Tomoki, Shimizu, Toshiyuki, Miyake, Kensuke
Published in International immunology (01.05.2016)
Published in International immunology (01.05.2016)
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Structural Analyses of Toll-like Receptor 7 Reveal Detailed RNA Sequence Specificity and Recognition Mechanism of Agonistic Ligands
Zhang, Zhikuan, Ohto, Umeharu, Shibata, Takuma, Taoka, Masato, Yamauchi, Yoshio, Sato, Ryota, Shukla, Nikunj M., David, Sunil A., Isobe, Toshiaki, Miyake, Kensuke, Shimizu, Toshiyuki
Published in Cell reports (Cambridge) (18.12.2018)
Published in Cell reports (Cambridge) (18.12.2018)
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TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction
Sakaniwa, Kentaro, Fujimura, Akiko, Shibata, Takuma, Shigematsu, Hideki, Ekimoto, Toru, Yamamoto, Masaki, Ikeguchi, Mitsunori, Miyake, Kensuke, Ohto, Umeharu, Shimizu, Toshiyuki
Published in Nature communications (11.01.2023)
Published in Nature communications (11.01.2023)
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Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages
Liu, Kaiwen, Sato, Ryota, Shibata, Takuma, Hiranuma, Ryosuke, Reuter, Tatjana, Fukui, Ryutaro, Zhang, Yun, Ichinohe, Takeshi, Ozawa, Manabu, Yoshida, Nobuaki, Latz, Eicke, Miyake, Kensuke
Published in International immunology (01.09.2021)
Published in International immunology (01.09.2021)
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Journal Article
Dynamic control of nucleic-acid-sensing Toll-like receptors by the endosomal compartment
Miyake, Kensuke, Saitoh, Shin-Ichiroh, Fukui, Ryutaro, Shibata, Takuma, Sato, Ryota, Murakami, Yusuke
Published in International Immunology (01.12.2021)
Published in International Immunology (01.12.2021)
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Book Review
Activated M2 Macrophages Contribute to the Pathogenesis of IgG4‐Related Disease via Toll‐like Receptor 7/Interleukin‐33 Signaling
Ishiguro, Noriko, Moriyama, Masafumi, Furusho, Katsuhiro, Furukawa, Sachiko, Shibata, Takuma, Murakami, Yusuke, Chinju, Akira, Haque, A. S. M. Rafiul, Gion, Yuka, Ohta, Miho, Maehara, Takashi, Tanaka, Akihiko, Yamauchi, Masaki, Sakamoto, Mizuki, Mochizuki, Keita, Ono, Yuko, Hayashida, Jun‐Nosuke, Sato, Yasuharu, Kiyoshima, Tamotsu, Yamamoto, Hidetaka, Miyake, Kensuke, Nakamura, Seiji
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2020)
Published in Arthritis & rheumatology (Hoboken, N.J.) (01.01.2020)
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Structural basis for species‐specific activation of mouse Toll‐like receptor 9
Ishida, Hanako, Ohto, Umeharu, Shibata, Takuma, Miyake, Kensuke, Shimizu, Toshiyuki
Published in FEBS letters (01.08.2018)
Published in FEBS letters (01.08.2018)
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Structural analysis reveals TLR7 dynamics underlying antagonism
Tojo, Shingo, Zhang, Zhikuan, Matsui, Hiroyuki, Tahara, Masahiro, Ikeguchi, Mitsunori, Kochi, Mami, Kamada, Mami, Shigematsu, Hideki, Tsutsumi, Akihisa, Adachi, Naruhiko, Shibata, Takuma, Yamamoto, Masaki, Kikkawa, Masahide, Senda, Toshiya, Isobe, Yoshiaki, Ohto, Umeharu, Shimizu, Toshiyuki
Published in Nature communications (15.10.2020)
Published in Nature communications (15.10.2020)
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Nucleic Acid Sensing by Toll-Like Receptors in the Endosomal Compartment
Miyake, Kensuke, Shibata, Takuma, Fukui, Ryutaro, Sato, Ryota, Saitoh, Shin-Ichiroh, Murakami, Yusuke
Published in Frontiers in immunology (23.06.2022)
Published in Frontiers in immunology (23.06.2022)
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The impact of cell maturation and tissue microenvironments on the expression of endosomal Toll-like receptors in monocytes and macrophages
Sato, Ryota, Reuter, Tatjana, Hiranuma, Ryosuke, Shibata, Takuma, Fukui, Ryutaro, Motoi, Yuji, Murakami, Yusuke, Tsukamoto, Hiroki, Yamazaki, Satoshi, Liu, Kaiwen, Saitoh, Shin-Ichiroh, Latz, Eicke, Miyake, Kensuke
Published in International immunology (01.12.2020)
Published in International immunology (01.12.2020)
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TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells
Saitoh, Shin-Ichiroh, Abe, Fumiko, Kanno, Atsuo, Tanimura, Natsuko, Mori Saitoh, Yoshiko, Fukui, Ryutaro, Shibata, Takuma, Sato, Katsuaki, Ichinohe, Takeshi, Hayashi, Mayumi, Kubota, Kazuishi, Kozuka-Hata, Hiroko, Oyama, Masaaki, Kikko, Yorifumi, Katada, Toshiaki, Kontani, Kenji, Miyake, Kensuke
Published in Nature communications (17.11.2017)
Published in Nature communications (17.11.2017)
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Unc93B1 Restricts Systemic Lethal Inflammation by Orchestrating Toll-like Receptor 7 and 9 Trafficking
Fukui, Ryutaro, Saitoh, Shin-Ichiroh, Kanno, Atsuo, Onji, Masahiro, Shibata, Takuma, Ito, Akihiko, Onji, Morikazu, Matsumoto, Mitsuru, Akira, Shizuo, Yoshida, Nobuaki, Miyake, Kensuke
Published in Immunity (Cambridge, Mass.) (22.07.2011)
Published in Immunity (Cambridge, Mass.) (22.07.2011)
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