Reductive carboxylation supports redox homeostasis during anchorage-independent growth
Jiang, Lei, Shestov, Alexander A, Swain, Pamela, Yang, Chendong, Parker, Seth J, Wang, Qiong A, Terada, Lance S, Adams, Nicholas D, McCabe, Michael T, Pietrak, Beth, Schmidt, Stan, Metallo, Christian M, Dranka, Brian P, Schwartz, Benjamin, DeBerardinis, Ralph J
Published in Nature (London) (14.04.2016)
Published in Nature (London) (14.04.2016)
Get full text
Journal Article
Characterization of the Usage of the Serine Metabolic Network in Human Cancer
Mehrmohamadi, Mahya, Liu, Xiaojing, Shestov, Alexander A., Locasale, Jason W.
Published in Cell reports (Cambridge) (20.11.2014)
Published in Cell reports (Cambridge) (20.11.2014)
Get full text
Journal Article
Inhibition of Mitochondrial Complex II by the Anticancer Agent Lonidamine
Guo, Lili, Shestov, Alexander A., Worth, Andrew J., Nath, Kavindra, Nelson, David S., Leeper, Dennis B., Glickson, Jerry D., Blair, Ian A.
Published in The Journal of biological chemistry (01.01.2016)
Published in The Journal of biological chemistry (01.01.2016)
Get full text
Journal Article
Mechanism of antineoplastic activity of lonidamine
Nath, Kavindra, Guo, Lili, Nancolas, Bethany, Nelson, David S., Shestov, Alexander A., Lee, Seung-Cheol, Roman, Jeffrey, Zhou, Rong, Leeper, Dennis B., Halestrap, Andrew P., Blair, Ian A., Glickson, Jerry D.
Published in Biochimica et biophysica acta (01.12.2016)
Published in Biochimica et biophysica acta (01.12.2016)
Get full text
Journal Article
A Flux Balance of Glucose Metabolism Clarifies the Requirements of the Warburg Effect
Dai, Ziwei, Shestov, Alexander A., Lai, Luhua, Locasale, Jason W.
Published in Biophysical journal (06.09.2016)
Published in Biophysical journal (06.09.2016)
Get full text
Journal Article
Quantitative determinants of aerobic glycolysis identify flux through the enzyme GAPDH as a limiting step
Shestov, Alexander A, Liu, Xiaojing, Ser, Zheng, Cluntun, Ahmad A, Hung, Yin P, Huang, Lei, Kim, Dongsung, Le, Anne, Yellen, Gary, Albeck, John G, Locasale, Jason W
Published in eLife (09.07.2014)
Published in eLife (09.07.2014)
Get full text
Journal Article
Metabolic Plasticity of Metastatic Breast Cancer Cells: Adaptation to Changes in the Microenvironment
Simões, Rui V, Serganova, Inna S, Kruchevsky, Natalia, Leftin, Avigdor, Shestov, Alexander A, Thaler, Howard T, Sukenick, George, Locasale, Jason W, Blasberg, Ronald G, Koutcher, Jason A, Ackerstaff, Ellen
Published in Neoplasia (New York, N.Y.) (01.08.2015)
Published in Neoplasia (New York, N.Y.) (01.08.2015)
Get full text
Journal Article
Impact of therapeutic inhibition of oncogenic cell signaling tyrosine kinase on cell metabolism: in vivo-detectable metabolic biomarkers of inhibition
Nath, Kavindra, Gupta, Pradeep K, Basappa, Johnvesly, Wang, Shengchun, Sen, Neil, Lobello, Cosimo, Tomar, Jyoti S, Shestov, Alexander A, Orlovskiy, Stepan, Arias-Mendoza, Fernando, Rauert-Wunderlich, Hilka, Nelson, David S, Glickson, Jerry D, Wasik, Mariusz A
Published in Journal of translational medicine (04.07.2024)
Published in Journal of translational medicine (04.07.2024)
Get full text
Journal Article
Simultaneous measurement of glucose transport and utilization in the human brain
Shestov, Alexander A, Emir, Uzay E, Kumar, Anjali, Henry, Pierre-Gilles, Seaquist, Elizabeth R, Öz, Gülin
Published in American journal of physiology: endocrinology and metabolism (01.11.2011)
Published in American journal of physiology: endocrinology and metabolism (01.11.2011)
Get full text
Journal Article
A Predictive Model for Selective Targeting of the Warburg Effect through GAPDH Inhibition with a Natural Product
Liberti, Maria V., Dai, Ziwei, Wardell, Suzanne E., Baccile, Joshua A., Liu, Xiaojing, Gao, Xia, Baldi, Robert, Mehrmohamadi, Mahya, Johnson, Marc O., Madhukar, Neel S., Shestov, Alexander A., Chio, Iok I. Christine, Elemento, Olivier, Rathmell, Jeffrey C., Schroeder, Frank C., McDonnell, Donald P., Locasale, Jason W.
Published in Cell metabolism (03.10.2017)
Published in Cell metabolism (03.10.2017)
Get full text
Journal Article
Bonded cumomer analysis of tumor metabolism based on 13C magnetic resonance spectroscopy
Shestov, Alexander A., Nath, Kavindra, Nelson, David S., Wasik, Mariusz A., Glickson, Jerry D.
Published in NMR in biomedicine (01.04.2023)
Published in NMR in biomedicine (01.04.2023)
Get full text
Journal Article
Bonded cumomer analysis of tumor metabolism based on 13 C magnetic resonance spectroscopy
Shestov, Alexander A, Nath, Kavindra, Nelson, David S, Wasik, Mariusz A, Glickson, Jerry D
Published in NMR in biomedicine (01.04.2023)
Published in NMR in biomedicine (01.04.2023)
Get full text
Journal Article
Metabolic Modeling of Dynamic (13)C NMR Isotopomer Data in the Brain In Vivo: Fast Screening of Metabolic Models Using Automated Generation of Differential Equations
Tiret, Brice, Shestov, Alexander A, Valette, Julien, Henry, Pierre-Gilles
Published in Neurochemical research (01.12.2015)
Published in Neurochemical research (01.12.2015)
Get full text
Journal Article
Skeletal muscle mitochondrial uncoupling in a murine cancer cachexia model
TZIKA, A. ARIA, FONTES-OLIVEIRA, CIBELY CRISTINE, SHESTOV, ALEXANDER A, CONSTANTINOU, CATERINA, PSYCHOGIOS, NIKOLAOS, RIGHI, VALERIA, MINTZOPOULOS, DIONYSSIOS, BUSQUETS, SILVIA, LOPEZ-SORIANO, FRANCISCO J, MILOT, SYLVAIN, LEPINE, FRANCOIS, MINDRINOS, MICHAEL N, RAHME, LAURENCE G, ARGILES, JOSEP M
Published in International journal of oncology (01.09.2013)
Published in International journal of oncology (01.09.2013)
Get full text
Journal Article
Metabolic Detection of Bruton's Tyrosine Kinase Inhibition in Mantle Cell Lymphoma Cells
Lee, Seung-Cheol, Shestov, Alexander A, Guo, Lili, Zhang, Qian, Roman, Jeffrey C, Liu, Xiaobin, Wang, Hong Y, Pickup, Stephen, Nath, Kavindra, Lu, Pin, Hofbauer, Samuel, Mesaros, Clementina, Wang, Y Lynn, Nelson, David S, Schuster, Stephen J, Blair, Ian A, Glickson, Jerry D, Wasik, Mariusz A
Published in Molecular cancer research (01.06.2019)
Published in Molecular cancer research (01.06.2019)
Get full text
Journal Article
Modeling of brain metabolism and pyruvate compartmentation using (13)C NMR in vivo: caution required
Jeffrey, F Mark, Marin-Valencia, Isaac, Good, Levi B, Shestov, Alexander A, Henry, Pierre-Gilles, Pascual, Juan M, Malloy, Craig R
Published in Journal of cerebral blood flow and metabolism (01.08.2013)
Published in Journal of cerebral blood flow and metabolism (01.08.2013)
Get full text
Journal Article
Bendamustine lymphodepletion before axicabtagene ciloleucel is safe and associates with reduced inflammatory cytokines
Ghilardi, Guido, Paruzzo, Luca, Svoboda, Jakub, Chong, Elise A., Shestov, Alexander A., Chen, Linhui, Cohen, Ivan J., Gabrielli, Giulia, Nasta, Sunita D., Porazzi, Patrizia, Landsburg, Daniel J., Gerson, James N., Carter, Jordan, Barta, Stefan K., Yelton, Rebecca, Pajarillo, Raymone, Patel, Vrutti, White, Griffin, Ballard, Hatcher J., Weber, Elizabeth, Napier, Ellen, Chong, Emeline R., Fraietta, Joseph A., Garfall, Alfred L., Porter, David L., Milone, Michael C., O’Connor, Roderick, Schuster, Stephen J., Ruella, Marco
Published in Blood advances (13.02.2024)
Published in Blood advances (13.02.2024)
Get full text
Journal Article