Antibody-Enzyme Conjugates for Cancer Therapy
Melton, Roger G., Sherwood, Roger F.
Published in JNCI : Journal of the National Cancer Institute (21.02.1996)
Published in JNCI : Journal of the National Cancer Institute (21.02.1996)
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Journal Article
Enhancement of trimetrexate cytotoxicity in vitro and in vivo by carboxypeptidase G2
Romanini, A, Sobrero, A F, Chou, T C, Sherwood, R F, Bertino, J R
Published in Cancer research (Chicago, Ill.) (01.11.1989)
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Published in Cancer research (Chicago, Ill.) (01.11.1989)
Journal Article
Studies on the nature of transition‐metal‐ion‐mediated binding of triazine dyes to enzymes
HUGHES, Peter, SHERWOOD, Roger F., LOWE, Christopher R.
Published in European journal of biochemistry (01.10.1984)
Published in European journal of biochemistry (01.10.1984)
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The bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)--I. Purification and properties of a nitroreductase enzyme from Escherichia coli--a potential enzyme for antibody-directed enzyme prodrug therapy (ADEPT)
Anlezark, G M, Melton, R G, Sherwood, R F, Coles, B, Friedlos, F, Knox, R J
Published in Biochemical pharmacology (15.12.1992)
Published in Biochemical pharmacology (15.12.1992)
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The bioactivation of 5-(aziridin-1-yl)-2,4-dinitrobenzamide (CB1954)--II. A comparison of an Escherichia coli nitroreductase and Walker DT diaphorase
Knox, R J, Friedlos, F, Sherwood, R F, Melton, R G, Anlezark, G M
Published in Biochemical pharmacology (15.12.1992)
Published in Biochemical pharmacology (15.12.1992)
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Journal Article
Galactosylated antibodies and antibody‐enzyme conjugates in antibody‐directed enzyme prodrug therapy
Sharma, Surinder K., Bagshawe, Kenneth D., Burke, Philip J., Boden, Joan A., Rogers, Gordon T., Springer, Caroline J., Melton, Roger G., Sherwood, Roger F.
Published in Cancer (01.02.1994)
Published in Cancer (01.02.1994)
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Journal Article
Conference Proceeding
Virtual cofactors for an Escherichia coli nitroreductase enzyme: Relevance to reductively activated prodrugs in antibody directed enzyme prodrug therapy (ADEPT)
Knox, Richard J., Friedlos, Frank, Jarman, Michael, Davies, Lawrence C., Goddard, Phyllis, Anlezark, Gillian M., Melton, Roger G., Sherwood, Roger F.
Published in Biochemical pharmacology (26.05.1995)
Published in Biochemical pharmacology (26.05.1995)
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Journal Article
In vitro and in vivo characterisation of a recombinant carboxypeptidase G2::anti-CEA scFv fusion protein
Michael, N.Paul, Chester, Kerry A., Melton, Roger G., Robson, Lynda, Nicholas, William, Boden, Joan A., Pedley, R.Barbara, Begent, Richard H.J., Sherwood, Roger F., Minton, Nigel P.
Published in Immunotechnology (Amsterdam, Netherlands) (01.02.1996)
Published in Immunotechnology (Amsterdam, Netherlands) (01.02.1996)
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Journal Article
The complete nucleotide sequence of the Pseudomonas gene coding for carboxypeptidase G2
Minton, Nigel P., Atkinson, Tony, Bruton, Chris J., Sherwood, Roger F.
Published in Gene (01.11.1984)
Published in Gene (01.11.1984)
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Journal Article
Biochemical and biological properties of methotrexate analogs containing D-glutamic acid or D-erythro, threo-4-fluoroglutamic acid
McGuire, J J, Bolanowska, W E, Coward, J K, Sherwood, R F, Russell, C A, Felschow, D M
Published in Biochemical pharmacology (27.11.1991)
Published in Biochemical pharmacology (27.11.1991)
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Large-scale protein extraction and isolation
Scawen, M D, Hammond, P M, Sherwood, R F, Atkinson, T
Published in Biochemical Society transactions (01.04.1990)
Published in Biochemical Society transactions (01.04.1990)
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Journal Article
Triazine-dye affinity; chromatography
Atkinson, T, Hammond, P M, Hartwell, R D, Hughes, P, Scawen, M D, Sherwood, R F, Small, D A, Bruton, C J, Harvey, M J, Lowe, C R
Published in Biochemical Society transactions (01.08.1981)
Published in Biochemical Society transactions (01.08.1981)
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