A Chemoproteomics Approach to Determine the Mechanism of Testicular Toxicity for the Bruton's Tyrosine Kinase Inhibitor CC-292
Labenski, Matt, Voortman, Lukas, Medikonda, Aravind Prasad, Sherratt, Philip J, Corin, Alan F
Published in The Journal of pharmacology and experimental therapeutics (01.11.2021)
Published in The Journal of pharmacology and experimental therapeutics (01.11.2021)
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Journal Article
The Carboxy-Terminal Neh3 Domain of Nrf2 Is Required for Transcriptional Activation
Nioi, Paul, Nguyen, Truyen, Sherratt, Philip J., Pickett, Cecil B.
Published in Molecular and Cellular Biology (01.12.2005)
Published in Molecular and Cellular Biology (01.12.2005)
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Journal Article
Nrf2 Controls Constitutive and Inducible Expression of ARE-driven Genes through a Dynamic Pathway Involving Nucleocytoplasmic Shuttling by Keap1
Nguyen, Truyen, Sherratt, Philip J., Nioi, Paul, Yang, Chung S., Pickett, Cecil B.
Published in The Journal of biological chemistry (16.09.2005)
Published in The Journal of biological chemistry (16.09.2005)
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Journal Article
Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome
Nguyen, Truyen, Sherratt, Philip J, Huang, H-C, Yang, Chung S, Pickett, Cecil B
Published in The Journal of biological chemistry (14.02.2003)
Published in The Journal of biological chemistry (14.02.2003)
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Journal Article
Erratum to “Prediction of non-genotoxic carcinogenesis in rats using changes in gene expression following acute dosing”
Nioi, Paul, Pardo, Ingrid D.R., Sherratt, Philip J., Fielden, Mark R., Gollub, Jeremy, Nie, Alex, Snyder, Ronald D.
Published in Chemico-biological interactions (25.11.2008)
Published in Chemico-biological interactions (25.11.2008)
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Journal Article
Direct Comparison of the Nature of Mouse and Human GST T1-1 and the Implications on Dichloromethane Carcinogenicity
Sherratt, Philip J., Williams, Sally, Foster, John, Kernohan, Neil, Green, Trevor, Hayes, John D.
Published in Toxicology and applied pharmacology (01.03.2002)
Published in Toxicology and applied pharmacology (01.03.2002)
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Journal Article
Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins
Kelly, Vincent P, Sherratt, Philip J, Crouch, Dorothy H, Hayes, John D
Published in Biochemical journal (15.09.2002)
Published in Biochemical journal (15.09.2002)
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Journal Article
Conjugation of Highly Reactive Aflatoxin B1 exo-8,9-Epoxide Catalyzed by Rat and Human Glutathione Transferases: Estimation of Kinetic Parameters
Johnson, William W, Ueng, Yune-Fang, Widersten, Mikael, Mannervik, Bengt, Hayes, John D, Sherratt, Philip J, Ketterer, Brian, Guengerich, F. Peter
Published in Biochemistry (Easton) (18.03.1997)
Published in Biochemistry (Easton) (18.03.1997)
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Journal Article
Paediatric excipient risk assessment (PERA) tool and application for selecting appropriate excipients for paediatric dosage forms – Part 2
Agrawal, Anjali, Salunke, Smita, Rumondor, Alfred, Thompson, Karen, Caivano, Grazia, Walsh, Jennifer, Enright, Brian, Sherratt, Philip, Hughes, Kevin, Clapham, David, Kuehl, Peter
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2024)
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2024)
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Journal Article
Selecting appropriate excipients for paediatric dosage form − Paediatric excipients risk assessment (PERA) framework – Part 1
Salunke, Smita, Agrawal, Anjali, Walsh, Jennifer, Nunn, Anthony, Hughes, Kevin, Kuehl, Peter, Caivano, Grazia, Clapham, David, Thompson, Karen, Rumondor, Alfred, Enright, Brian, Sherratt, Philip
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2024)
Published in European journal of pharmaceutics and biopharmaceutics (01.10.2024)
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Journal Article
Next‐Generation DILI Biomarkers: Prioritization of Biomarkers for Qualification and Best Practices for Biospecimen Collection in Drug Development
Roth, Sharin E., Avigan, Mark I., Bourdet, David, Brott, David, Church, Rachel, Dash, Ajit, Keller, Douglas, Sherratt, Philip, Watkins, Paul B., Westcott‐Baker, Lucas, Lentini, Silvia, Merz, Michael, Ramaiah, Lila, Ramaiah, Shashi K., Stanley, Ann Marie, Marcinak, John
Published in Clinical pharmacology and therapeutics (01.02.2020)
Published in Clinical pharmacology and therapeutics (01.02.2020)
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Journal Article
An analysis of pharmaceutical experience with decades of rat carcinogenicity testing: support for a proposal to modify current regulatory guidelines
Sistare, Frank D, Morton, Daniel, Alden, Carl, Christensen, Joel, Keller, Douglas, Jonghe, Sandra De, Storer, Richard D, Reddy, M Vijayaraj, Kraynak, Andrew, Trela, Bruce, Bienvenu, Jean-Guy, Bjurström, Sivert, Bosmans, Vanessa, Brewster, David, Colman, Karyn, Dominick, Mark, Evans, John, Hailey, James R, Kinter, Lewis, Liu, Matt, Mahrt, Charles, Marien, Dirk, Myer, James, Perry, Richard, Potenta, Daniel, Roth, Arthur, Sherratt, Philip, Singer, Thomas, Slim, Rabih, Soper, Keith, Fransson-Steen, Ronny, Stoltz, James, Turner, Oliver, Turnquist, Susan, van Heerden, Marjolein, Woicke, Jochen, DeGeorge, Joseph J
Published in Toxicologic pathology (01.06.2011)
Published in Toxicologic pathology (01.06.2011)
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Journal Article
Increased Protein Stability as a Mechanism That Enhances Nrf2-mediated Transcriptional Activation of the Antioxidant Response Element
Nguyen, Truyen, Sherratt, Philip J., Huang, H.-C., Yang, Chung S., Pickett, Cecil B.
Published in The Journal of biological chemistry (14.02.2003)
Published in The Journal of biological chemistry (14.02.2003)
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Journal Article
세레블론 개질 화합물을 스크리닝하는 방법
CHAMBERLAIN PHILIP, MATYSKIELA MARY, SHERRATT PHILIP J, COUTO SUZANA STURLINI, LU GANG, HUI JULIA, STAMP KATHERINE
Year of Publication 18.09.2020
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Year of Publication 18.09.2020
Patent
Evidence that human class Theta glutathione S-transferase T1-1 can catalyse the activation of dichloromethane, a liver and lung carcinogen in the mouse. Comparison of the tissue distribution of GST T1-1 with that of classes Alpha, Mu and Pi GST in human
Sherratt, P J, Pulford, D J, Harrison, D J, Green, T, Hayes, J D
Published in Biochemical journal (15.09.1997)
Published in Biochemical journal (15.09.1997)
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Journal Article