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Biarylaniline Phenethanolamines as Potent and Selective β3 Adrenergic Receptor Agonists

Biarylaniline Phenethanolamines as Potent and Selective β3 Adrenergic Receptor Agonists

by Uehling, David E, Shearer, Barry G, Donaldson, Kelly H, Chao, Esther Y, Deaton, David N, Adkison, Kim K, Brown, Kathleen K, Cariello, Neal F, Faison, Walter L, Lancaster, Mary E, Lin, Jasmine, Hart, Robert, Milliken, Tula O, Paulik, Mark A, Sherman, Bryan W, Sugg, Elizabeth E, Cowan, Conrad
Published in Journal of medicinal chemistry (04.05.2006)

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Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing heterobiaryl carboxylic acids

Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing heterobiaryl carboxylic acids

by Shearer, Barry G., Chao, Esther Y., Uehling, David E., Deaton, David N., Cowan, Conrad, Sherman, Bryan W., Milliken, Tula, Faison, Walter, Brown, Kathleen, Adkison, Kimberly K., Lee, Frank
Published in Bioorganic & medicinal chemistry letters (15.08.2007)

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Synthesis and Evaluation of Potent and Selective β3 Adrenergic Receptor Agonists Containing Acylsulfonamide, Sulfonylsulfonamide, and Sulfonylurea Carboxylic Acid Isosteres

Synthesis and Evaluation of Potent and Selective β3 Adrenergic Receptor Agonists Containing Acylsulfonamide, Sulfonylsulfonamide, and Sulfonylurea Carboxylic Acid Isosteres

by Uehling, David E, Donaldson, Kelly H, Deaton, David N, Hyman, Clifton E, Sugg, Elizabeth E, Barrett, David G, Hughes, Robert G, Reitter, Barbara, Adkison, Kim K, Lancaster, Mary E, Lee, Frank, Hart, Robert, Paulik, Mark A, Sherman, Bryan W, True, Timothy, Cowan, Conrad
Published in Journal of medicinal chemistry (31.01.2002)

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2-(anilinomethyl)imidazolines as α1 adrenergic receptor agonists : α1a subtype selective 2'-heteroaryl compounds

2-(anilinomethyl)imidazolines as α1 adrenergic receptor agonists : α1a subtype selective 2'-heteroaryl compounds

by SPEAKE, Jason D, NAVAS, Frank III, BISHOP, Michael J, GARRISON, Deanna T, BIGHAM, Eric C, HODSON, Stephen J, SAUSSY, David L, LIACOS, Jim A, IRVING, Paul E, SHERMAN, Bryan W
Published in Bioorganic & medicinal chemistry letters (24.03.2003)

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α1-Adrenoceptor activation: A comparison of 4-(anilinomethyl)imidazoles and 4-(phenoxymethyl)imidazoles to related 2-imidazolines

α1-Adrenoceptor activation: A comparison of 4-(anilinomethyl)imidazoles and 4-(phenoxymethyl)imidazoles to related 2-imidazolines

by HODSON, Stephen J, BIGHAM, Eric C, BISHOP, Michael J, GARRISON, Deanna T, GOBEL, Michael J, IRVING, Paul E, LIACOS, James A, NAVAS, Frank III, SAUSSY, David L, SHERMAN, Bryan W, SPEAKE, Jason D
Published in Bioorganic & medicinal chemistry letters (01.12.2002)

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2-(Anilinomethyl)imidazolines as α1 Adrenergic Receptor Agonists: the Discovery of α1 a Subtype Selective 2‘-Alkylsulfonyl-Substituted Analogues

2-(Anilinomethyl)imidazolines as α1 Adrenergic Receptor Agonists: the Discovery of α1 a Subtype Selective 2‘-Alkylsulfonyl-Substituted Analogues

by Hodson, Stephen J, Bishop, Michael J, Speake, Jason D, Navas, Frank, Garrison, Deanna T, Bigham, Eric C, Saussy, David L, Liacos, James A, Irving, Paul E, Gobel, M. Jeffrey, Sherman, Bryan W
Published in Journal of medicinal chemistry (23.05.2002)

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Journal Article

Synthesis and evaluation of potent and selective beta3 adrenergic receptor agonists containing heterobiaryl carboxylic acids

Synthesis and evaluation of potent and selective beta3 adrenergic receptor agonists containing heterobiaryl carboxylic acids

by Shearer, Barry G, Chao, Esther Y, Uehling, David E, Deaton, David N, Cowan, Conrad, Sherman, Bryan W, Milliken, Tula, Faison, Walter, Brown, Kathleen, Adkison, Kimberly K, Lee, Frank
Published in Bioorganic & medicinal chemistry letters (15.08.2007)

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Journal Article

Synthesis and evaluation of potent and selective beta sub(3) adrenergic receptor agonists containing heterobiaryl carboxylic acids

Synthesis and evaluation of potent and selective beta sub(3) adrenergic receptor agonists containing heterobiaryl carboxylic acids

by Shearer, Barry G, Chao, Esther Y, Uehling, David E, Deaton, David N, Cowan, Conrad, Sherman, Bryan W, Milliken, Tula, Faison, Walter, Brown, Kathleen, Adkison, Kimberly K, Lee, Frank
Published in Bioorganic & medicinal chemistry letters (01.08.2007)

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Synthesis and evaluation of potent and selective beta(3) adrenergic receptor agonists containing acylsulfonamide, sulfonylsulfonamide, and sulfonylurea carboxylic acid isosteres

Synthesis and evaluation of potent and selective beta(3) adrenergic receptor agonists containing acylsulfonamide, sulfonylsulfonamide, and sulfonylurea carboxylic acid isosteres

by Uehling, DE, Donaldson, KH, Deaton, DN, Hyman, CE, Sugg, EE, Barrett, DG, Hughes, RG, Reitter, B, Adkison, KK, Lancaster, ME, Lee, F, Hart, R, Paulik, MA, Sherman, BW, True, T, Cowan, C
Published in Journal of medicinal chemistry (31.01.2002)

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Journal Article

Biarylaniline phenethanolamines as potent and selective beta3 adrenergic receptor agonists

Biarylaniline phenethanolamines as potent and selective beta3 adrenergic receptor agonists

by Uehling, David E, Shearer, Barry G, Donaldson, Kelly H, Chao, Esther Y, Deaton, David N, Adkison, Kim K, Brown, Kathleen K, Cariello, Neal F, Faison, Walter L, Lancaster, Mary E, Lin, Jasmine, Hart, Robert, Milliken, Tula O, Paulik, Mark A, Sherman, Bryan W, Sugg, Elizabeth E, Cowan, Conrad
Published in Journal of medicinal chemistry (04.05.2006)

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Journal Article

Biarylaniline Phenethanolamines as Potent and Selective β 3 Adrenergic Receptor Agonists

Biarylaniline Phenethanolamines as Potent and Selective β 3 Adrenergic Receptor Agonists

by Uehling, David E., Shearer, Barry G., Donaldson, Kelly H., Chao, Esther Y., Deaton, David N., Adkison, Kim K., Brown, Kathleen K., Cariello, Neal F., Faison, Walter L., Lancaster, Mary E., Lin, Jasmine, Hart, Robert, Milliken, Tula O., Paulik, Mark A., Sherman, Bryan W., Sugg, Elizabeth E., Cowan, Conrad
Published in Journal of medicinal chemistry (01.05.2006)

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Journal Article

2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: alpha1a subtype selective 2'-heteroaryl compounds

2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: alpha1a subtype selective 2'-heteroaryl compounds

by Speake, Jason D, Navas, Frank, Bishop, Michael J, Garrison, Deanna T, Bigham, Eric C, Hodson, Stephen J, Saussy, David L, Liacos, Jim A, Irving, Paul E, Sherman, Bryan W
Published in Bioorganic & medicinal chemistry letters (24.03.2003)

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2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: the discovery of alpha1a subtype selective 2'-alkylsulfonyl-substituted analogues

2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: the discovery of alpha1a subtype selective 2'-alkylsulfonyl-substituted analogues

by Hodson, Stephen J, Bishop, Michael J, Speake, Jason D, Navas, 3rd, Frank, Garrison, Deanna T, Bigham, Eric C, Saussy, Jr, David L, Liacos, James A, Irving, Paul E, Gobel, M Jeffrey, Sherman, Bryan W
Published in Journal of medicinal chemistry (23.05.2002)

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Journal Article

2-(Anilinomethyl)imidazolines as α 1 Adrenergic Receptor Agonists: the Discovery of α 1 a Subtype Selective 2‘-Alkylsulfonyl-Substituted Analogues

2-(Anilinomethyl)imidazolines as α 1 Adrenergic Receptor Agonists: the Discovery of α 1 a Subtype Selective 2‘-Alkylsulfonyl-Substituted Analogues

by Hodson, Stephen J., Bishop, Michael J., Speake, Jason D., Navas, Frank, Garrison, Deanna T., Bigham, Eric C., Saussy, David L., Liacos, James A., Irving, Paul E., Gobel, M. Jeffrey, Sherman, Bryan W.
Published in Journal of medicinal chemistry (01.05.2002)

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Journal Article

2-(Anilinomethyl)imidazolines as α 1 adrenergic receptor agonists: α 1a subtype selective 2′-heteroaryl compounds

2-(Anilinomethyl)imidazolines as α 1 adrenergic receptor agonists: α 1a subtype selective 2′-heteroaryl compounds

by Speake, Jason D., Navas, Frank, Bishop, Michael J., Garrison, Deanna T., Bigham, Eric C., Hodson, Stephen J., Saussy, David L., Liacos, Jim A., Irving, Paul E., Sherman, Bryan W.
Published in Bioorganic & medicinal chemistry letters (2003)

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Journal Article

Alpha(1)-adrenoceptor activation: a comparison of 4-(anilinomethyl)imidazoles and 4-(phenoxymethyl)imidazoles to related 2-imidazolines

Alpha(1)-adrenoceptor activation: a comparison of 4-(anilinomethyl)imidazoles and 4-(phenoxymethyl)imidazoles to related 2-imidazolines

by Hodson, Stephen J, Bigham, Eric C, Garrison, Deanna T, Gobel, Michael J, Irving, Paul E, Liacos, James A, Navas, 3rd, Frank, Saussy, Jr, David L, Sherman, Bryan W, Speake, Jason D, Bishop, Michael J
Published in Bioorganic & medicinal chemistry letters (02.12.2002)

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Journal Article

α 1-Adrenoceptor activation: A comparison of 4-(Anilinomethyl)imidazoles and 4-(Phenoxymethyl)imidazoles to related 2-imidazolines

α 1-Adrenoceptor activation: A comparison of 4-(Anilinomethyl)imidazoles and 4-(Phenoxymethyl)imidazoles to related 2-imidazolines

by Hodson, Stephen J, Bigham, Eric C, Garrison, Deanna T, Gobel, Michael J, Irving, Paul E, Liacos, James A, Navas, III, Frank, Saussy, David L, Sherman, Bryan W, Speake, Jason D, Bishop, Michael J
Published in Bioorganic & medicinal chemistry letters (2002)

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Journal Article

Synthesis and Evaluation of Potent and Selective β 3 Adrenergic Receptor Agonists Containing Acylsulfonamide, Sulfonylsulfonamide, and Sulfonylurea Carboxylic Acid Isosteres

Synthesis and Evaluation of Potent and Selective β 3 Adrenergic Receptor Agonists Containing Acylsulfonamide, Sulfonylsulfonamide, and Sulfonylurea Carboxylic Acid Isosteres

by Uehling, David E., Donaldson, Kelly H., Deaton, David N., Hyman, Clifton E., Sugg, Elizabeth E., Barrett, David G., Hughes, Robert G., Reitter, Barbara, Adkison, Kim K., Lancaster, Mary E., Lee, Frank, Hart, Robert, Paulik, Mark A., Sherman, Bryan W., True, Timothy, Cowan, Conrad
Published in Journal of medicinal chemistry (01.01.2002)

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Journal Article

2-(Anilinomethyl)imidazolines as α1 Adrenergic Receptor Agonists: α1a Subtype Selective 2′-Heteroaryl Compounds

2-(Anilinomethyl)imidazolines as α1 Adrenergic Receptor Agonists: α1a Subtype Selective 2′-Heteroaryl Compounds

by Speake, Jason D., Navas, Frank III, Bishop, Michael J., Garrison, Deanna T., Bigham, Eric C., Hodson, Stephen J., Saussy, David L., Liacos, Jim A., Irving, Paul E., Sherman, Bryan W.
Published in ChemInform (29.07.2003)

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Journal Article

2‐(Anilinomethyl)imidazolines as α 1 Adrenergic Receptor Agonists: α 1a Subtype Selective 2′‐Heteroaryl Compounds

2‐(Anilinomethyl)imidazolines as α 1 Adrenergic Receptor Agonists: α 1a Subtype Selective 2′‐Heteroaryl Compounds

by Speake, Jason D., Navas, Frank III, Bishop, Michael J., Garrison, Deanna T., Bigham, Eric C., Hodson, Stephen J., Saussy, David L., Liacos, Jim A., Irving, Paul E., Sherman, Bryan W.
Published in ChemInform (29.07.2003)

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Journal Article