PRMT5 arginine methyltransferase: many roles in development, cancer and beyond
Stopa, Nicole, Krebs, Jocelyn E, Shechter, David
Published in Cellular and molecular life sciences : CMLS (01.06.2015)
Published in Cellular and molecular life sciences : CMLS (01.06.2015)
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Journal Article
Cellular consequences of arginine methylation
Lorton, Benjamin M., Shechter, David
Published in Cellular and molecular life sciences : CMLS (01.08.2019)
Published in Cellular and molecular life sciences : CMLS (01.08.2019)
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Journal Article
Extraction, purification and analysis of histones
Hake, Sandra B, Shechter, David, Dormann, Holger L, Allis, C David
Published in Nature protocols (01.06.2007)
Published in Nature protocols (01.06.2007)
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Journal Article
Histone H2A and H4 N-terminal Tails Are Positioned by the MEP50 WD Repeat Protein for Efficient Methylation by the PRMT5 Arginine Methyltransferase
Burgos, Emmanuel S., Wilczek, Carola, Onikubo, Takashi, Bonanno, Jeffrey B., Jansong, Janina, Reimer, Ulf, Shechter, David
Published in The Journal of biological chemistry (10.04.2015)
Published in The Journal of biological chemistry (10.04.2015)
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Journal Article
Dynamic intramolecular regulation of the histone chaperone nucleoplasmin controls histone binding and release
Warren, Christopher, Matsui, Tsutomu, Karp, Jerome M., Onikubo, Takashi, Cahill, Sean, Brenowitz, Michael, Cowburn, David, Girvin, Mark, Shechter, David
Published in Nature communications (20.12.2017)
Published in Nature communications (20.12.2017)
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Journal Article
Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation
Maron, Maxim I, Casill, Alyssa D, Gupta, Varun, Roth, Jacob S, Sidoli, Simone, Query, Charles C, Gamble, Matthew J, Shechter, David
Published in eLife (05.01.2022)
Published in eLife (05.01.2022)
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Journal Article
Structure of the arginine methyltransferase PRMT5-MEP50 reveals a mechanism for substrate specificity
Ho, Meng-Chiao, Wilczek, Carola, Bonanno, Jeffrey B, Xing, Li, Seznec, Janina, Matsui, Tsutomu, Carter, Lester G, Onikubo, Takashi, Kumar, P Rajesh, Chan, Man K, Brenowitz, Michael, Cheng, R Holland, Reimer, Ulf, Almo, Steven C, Shechter, David
Published in PloS one (25.02.2013)
Published in PloS one (25.02.2013)
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Journal Article
Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells
Ravichandran, Mirunalini, Lei, Run, Tang, Qin, Zhao, Yilin, Lee, Joun, Ma, Liyang, Chrysanthou, Stephanie, Lorton, Benjamin M., Cvekl, Ales, Shechter, David, Zheng, Deyou, Dawlaty, Meelad M.
Published in Cell reports (Cambridge) (20.08.2019)
Published in Cell reports (Cambridge) (20.08.2019)
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Journal Article
Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans
Walters, Ryan O., Arias, Esperanza, Diaz, Antonio, Burgos, Emmanuel S., Guan, Fangxia, Tiano, Simoni, Mao, Kai, Green, Cara L., Qiu, Yungping, Shah, Hardik, Wang, Donghai, Hudgins, Adam D., Tabrizian, Tahmineh, Tosti, Valeria, Shechter, David, Fontana, Luigi, Kurland, Irwin J., Barzilai, Nir, Cuervo, Ana Maria, Promislow, Daniel E.L., Huffman, Derek M.
Published in Cell reports (Cambridge) (16.10.2018)
Published in Cell reports (Cambridge) (16.10.2018)
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Journal Article
Regulation of DNA replication by ATR: signaling in response to DNA intermediates
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Book Review
Journal Article
Protein Arginine Methyltransferase Prmt5-Mep50 Methylates Histones H2A and H4 and the Histone Chaperone Nucleoplasmin in Xenopus laevis Eggs
Wilczek, Carola, Chitta, Raghu, Woo, Eileen, Shabanowitz, Jeffrey, Chait, Brian T., Hunt, Donald F., Shechter, David
Published in The Journal of biological chemistry (09.12.2011)
Published in The Journal of biological chemistry (09.12.2011)
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Journal Article
Glutamylation of Npm2 and Nap1 acidic disordered regions increases DNA mimicry and histone chaperone efficiency
Lorton, Benjamin M., Warren, Christopher, Ilyas, Humaira, Nandigrami, Prithviraj, Hegde, Subray, Cahill, Sean, Lehman, Stephanie M., Shabanowitz, Jeffrey, Hunt, Donald F., Fiser, Andras, Cowburn, David, Shechter, David
Published in iScience (19.04.2024)
Published in iScience (19.04.2024)
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Journal Article
Independent transcriptomic and proteomic regulation by type I and II protein arginine methyltransferases
Maron, Maxim I., Lehman, Stephanie M., Gayatri, Sitaram, DeAngelo, Joseph D., Hegde, Subray, Lorton, Benjamin M., Sun, Yan, Bai, Dina L., Sidoli, Simone, Gupta, Varun, Marunde, Matthew R., Bone, James R., Sun, Zu-Wen, Bedford, Mark T., Shabanowitz, Jeffrey, Chen, Hongshan, Hunt, Donald F., Shechter, David
Published in iScience (24.09.2021)
Published in iScience (24.09.2021)
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Journal Article
Developmentally Regulated Post-translational Modification of Nucleoplasmin Controls Histone Sequestration and Deposition
Onikubo, Takashi, Nicklay, Joshua J., Xing, Li, Warren, Christopher, Anson, Brandon, Wang, Wei-Lin, Burgos, Emmanuel S., Ruff, Sophie E., Shabanowitz, Jeffrey, Cheng, R. Holland, Hunt, Donald F., Shechter, David
Published in Cell reports (Cambridge) (17.03.2015)
Published in Cell reports (Cambridge) (17.03.2015)
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Journal Article
distinct H2A.X isoform is enriched in Xenopus laevis eggs and early embryos and is phosphorylated in the absence of a checkpoint
Shechter, David, Chitta, Raghu K, Xiao, Andrew, Shabanowitz, Jeffrey, Hunt, Donald F, Allis, C. David
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (20.01.2009)
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