Arterial Platelet Adhesion in Atherosclerosis-Prone Arteries of Obese, Insulin-Resistant Nonhuman Primates
Brown, Eran, Ozawa, Koya, Moccetti, Federico, Vinson, Amanda, Hodovan, James, Nguyen, The Anh, Bader, Lindsay, López, José A, Kievit, Paul, Shaw, Gray D, Chung, Dominic W, Osborn, Warren, Fu, Xiaoyun, Chen, Junmei, Lindner, Jonathan R
Published in Journal of the American Heart Association (04.05.2021)
Published in Journal of the American Heart Association (04.05.2021)
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Glycoprotein Ibα inhibitor (CCP-224) prevents neutrophil-platelet aggregation in sickle cell disease
Jimenez, Maritza A., Novelli, Enrico M., Shaw, Gray D., Sundd, Prithu
Published in Blood advances (12.09.2017)
Published in Blood advances (12.09.2017)
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The von Willebrand factor antagonist (GPG-290) prevents coronary thrombosis without prolongation of bleeding time
Wadanoli, Michael, Sako, Dianne, Shaw, Gray D, Schaub, Robert G, Wang, Qin, Tchernychev, Boris, Xu, Jin, Porter, Thomas J, Huang, Qinheng
Published in Thrombosis and haemostasis (01.08.2007)
Published in Thrombosis and haemostasis (01.08.2007)
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Discovery of 2-[1-(4-Chlorophenyl)cyclopropyl]-3-hydroxy-8-(trifluoromethyl)quinoline-4-carboxylic Acid (PSI-421), a P-Selectin Inhibitor with Improved Pharmacokinetic Properties and Oral Efficacy in Models of Vascular Injury
Huang, Adrian, Moretto, Alessandro, Janz, Kristin, Lowe, Michael, Bedard, Patricia W, Tam, Steve, Di, Li, Clerin, Valerie, Sushkova, Natalia, Tchernychev, Boris, Tsao, Desiree H. H, Keith, James C, Shaw, Gray D, Schaub, Robert G, Wang, Qin, Kaila, Neelu
Published in Journal of medicinal chemistry (26.08.2010)
Published in Journal of medicinal chemistry (26.08.2010)
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2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[H]quinoline-4-carboxylic Acid (PSI-697): Identification of a Clinical Candidate from the Quinoline Salicylic Acid Series of P-Selectin Antagonists
Kaila, Neelu, Janz, Kristin, Huang, Adrian, Moretto, Alessandro, DeBernardo, Silvano, Bedard, Patricia W, Tam, Steve, Clerin, Valerie, Keith, James C, Tsao, Desirée H. H, Sushkova, Natalia, Shaw, Gray D, Camphausen, Raymond T, Schaub, Robert G, Wang, Qin
Published in Journal of medicinal chemistry (11.01.2007)
Published in Journal of medicinal chemistry (11.01.2007)
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Characterization of the Novel P-Selectin Inhibitor PSI-697 [2-(4-Chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobenzo[h] Quinoline-4-carboxylic acid] in Vitro and in Rodent Models of Vascular Inflammation and Thrombosis
Bedard, Patricia W, Clerin, Valerie, Sushkova, Natalia, Tchernychev, Boris, Antrilli, Thomas, Resmini, Christine, Keith, Jr, James C, Hennan, James K, Kaila, Neelu, Debernardo, Silvano, Janz, Kristin, Wang, Qin, Crandall, David L, Schaub, Robert G, Shaw, Gray D, Carter, Laura L
Published in The Journal of pharmacology and experimental therapeutics (01.02.2008)
Published in The Journal of pharmacology and experimental therapeutics (01.02.2008)
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SLIC-1/sorting nexin 20: A novel sorting nexin that directs subcellular distribution of PSGL-1
Schaff, Ulrich Y, Shih, Heather H, Lorenz, Meike, Sako, Dianne, Kriz, Ron, Milarski, Kim, Bates, Brian, Tchernychev, Boris, Shaw, Gray D, Simon, Scott I
Published in European journal of immunology (01.02.2008)
Published in European journal of immunology (01.02.2008)
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Pharmacologic inhibition of platelet vWF-GPIb alpha interaction prevents coronary artery thrombosis
Hennan, James K, Swillo, Robert E, Morgan, Gwen A, Leik, Courtney E, Brooks, Jonathan M, Shaw, Gray D, Schaub, Robert G, Crandall, David L, Vlasuk, George P
Published in Thrombosis and haemostasis (01.03.2006)
Published in Thrombosis and haemostasis (01.03.2006)
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Decreased venous thrombosis with an oral inhibitor of P selectin
Myers, Daniel D., Rectenwald, John E., Bedard, Patricia W., Kaila, Neelu, Shaw, Gray D., Schaub, Robert G., Farris, Diana M., Hawley, Angela E., Wrobleski, Shirley K., Henke, Peter K., Wakefield, Thomas W.
Published in Journal of vascular surgery (01.08.2005)
Published in Journal of vascular surgery (01.08.2005)
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Identification of Peptide Antagonists to Glycoprotein Ibα That Selectively Inhibit von Willebrand Factor Dependent Platelet Aggregation
Benard, Susan Adam, Smith, Thomas M, Cunningham, Kristina, Jacob, Jaison, DeSilva, Thamara, Lin, Laura, Shaw, Gray D, Kriz, Ron, Kelleher, Kerry S
Published in Biochemistry (Easton) (22.04.2008)
Published in Biochemistry (Easton) (22.04.2008)
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Molecular Characterization of Rat Leukocyte P-Selectin Glycoprotein Ligand-1 and Effect of Its Blockade: Protection from Ischemia-Reperfusion Injury in Liver Transplantation
Tsuchihashi, Sei-ichiro, Fondevila, Constantino, Shaw, Gray D, Lorenz, Meike, Marquette, Kimberly, Benard, Susan, Shen, Xiu-Da, Ke, Bibo, Busuttil, Ronald W, Kupiec-Weglinski, Jerzy W
Published in Journal of Immunology (01.01.2006)
Published in Journal of Immunology (01.01.2006)
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Expression cloning of a functional glycoprotein ligand for P-selectin
Sako, Dianne, Chang, Xiao-Jia, Barone, Karen M., Vachino, Gloria, White, Holly M., Shaw, Gray, Veldman, Geertruida M., Bean, Kevin M., Ahern, Tim J., Furie, Bruce, Cumming, Dale A., Larsen, Glenn R.
Published in Cell (17.12.1993)
Published in Cell (17.12.1993)
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Normalization of brain death-induced injury to rat renal allografts by recombinant soluble P-selectin glycoprotein ligand
GASSER, Martin, WAAGA, Ana Maria, HOLTHE, Joana E. Kist-Van, LENHARD, Susanne M, LASKOWSKI, Igor, SHAW, Gray D, HANCOCK, Wayne W, TILNEY, Nicholas L
Published in Journal of the American Society of Nephrology (01.07.2002)
Published in Journal of the American Society of Nephrology (01.07.2002)
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P‐Selectin Glycoprotein Ligand‐1 (rPSGL‐Ig)‐Mediated Blockade of CD62 Selectin Molecules Protects Rat Steatotic Liver Grafts from Ischemia/Reperfusion Injury
Amersi, Farin, Farmer, Douglas G., Shaw, Gray D., Kato, Hirohisa, Coito, Ana J., Kaldas, Fady, Zhao, Delai, Lassman, Charles R., Melinek, Judy, Ma, Jeffrey, Volk, Hans‐Dieter, Kupiec‐Weglinski, Jerzy W., Busuttil, Ronald W.
Published in American journal of transplantation (01.08.2002)
Published in American journal of transplantation (01.08.2002)
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CD62 blockade with P-Selectin glycoprotein ligand-immunoglobulin fusion protein reduces ischemia-reperfusion injury after rat intestinal transplantation
Farmer, Douglas G, Shen, Xiu-Da, Amersi, Farin, Anselmo, Dean, Ma, Jeffrey P, Ke, Bibo, Gao, Feng, Dry, Sarah, Fernandez, Susan, Shaw, Gray D, McDiarmid, Sue V, Busuttil, Ronald W, Kupiec-Weglinski, Jerzy
Published in Transplantation (15.01.2005)
Published in Transplantation (15.01.2005)
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Selectin Blockade Plus Therapy with Low‐Dose Sirolimus and Cyclosporin A Prevent Brain Death‐Induced Renal Allograft Dysfunction
Gasser, Martin, Waaga‐Gasser, Ana Maria, Grimm, Michael W., Grimm, Martin R., Lenhard, Miriam S., Kist‐van Holthe, Joana E., Laskowski, Igor, Shaw, Gray D., Thiede, Arnulf, Hancock, Wayne W., Tilney, Nicholas L.
Published in American journal of transplantation (01.04.2005)
Published in American journal of transplantation (01.04.2005)
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A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin binding
Sako, Dianne, Comess, Kenneth M., Barone, Karen M., Camphausen, Raymond T., Cumming, Dale A., Shaw, Gray D.
Published in Cell (20.10.1995)
Published in Cell (20.10.1995)
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