Argonaute Utilization for miRNA Silencing Is Determined by Phosphorylation-Dependent Recruitment of LIM-Domain-Containing Proteins
Bridge, Katherine S., Shah, Kunal M., Li, Yigen, Foxler, Daniel E., Wong, Sybil C.K., Miller, Duncan C., Davidson, Kathryn M., Foster, John G., Rose, Ruth, Hodgkinson, Michael R., Ribeiro, Paulo S., Aboobaker, A. Aziz, Yashiro, Kenta, Wang, Xiaozhong, Graves, Paul R., Plevin, Michael J., Lagos, Dimitris, Sharp, Tyson V.
Published in Cell reports (Cambridge) (05.07.2017)
Published in Cell reports (Cambridge) (05.07.2017)
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Journal Article
SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians
González-Estévez, Cristina, Felix, Daniel A, Smith, Matthew D, Paps, Jordi, Morley, Simon J, James, Victoria, Sharp, Tyson V, Aboobaker, A Aziz
Published in PLoS genetics (01.03.2012)
Published in PLoS genetics (01.03.2012)
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Journal Article
The hypoxic tumor microenvironment: driving the tumorigenesis of non-small-cell lung cancer
Foster, John G, Wong, Sybil CK, Sharp, Tyson V
Published in Future oncology (London, England) (01.12.2014)
Published in Future oncology (London, England) (01.12.2014)
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Journal Article
Targeted therapy for LIMD1-deficient non-small cell lung cancer subtypes
Davidson, Kathryn, Grevitt, Paul, Contreras-Gerenas, Maria F, Bridge, Katherine S, Hermida, Miguel, Shah, Kunal M, Mardakheh, Faraz K, Stubbs, Mark, Burke, Rosemary, Casado, Pedro, Cutillas, Pedro R, Martin, Sarah A, Sharp, Tyson V
Published in Cell death & disease (11.11.2021)
Published in Cell death & disease (11.11.2021)
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Journal Article
Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters
Miller, Duncan C., Harmer, Stephen C., Poliandri, Ariel, Nobles, Muriel, Edwards, Elizabeth C., Ware, James S., Sharp, Tyson V., McKay, Tristan R., Dunkel, Leo, Lambiase, Pier D., Tinker, Andrew
Published in Stem cell research (01.12.2017)
Published in Stem cell research (01.12.2017)
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Journal Article
The M Type K15 Protein of Kaposi's Sarcoma-Associated Herpesvirus Regulates MicroRNA Expression via Its SH2-Binding Motif To Induce Cell Migration and Invasion
TSAI, Yuan-Hau, WU, Min-Fen, WU, Yu-Hsuan, CHANG, Shing-Jyh, LIN, Su-Fang, SHARP, Tyson V, WANG, Hsei-Wei
Published in Journal of Virology (01.01.2009)
Published in Journal of Virology (01.01.2009)
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Journal Article
LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for microRNA-mediated gene silencing
James, Victoria, Zhang, Yining, Foxler, Daniel E., de Moor, Cornelia H., Kong, Yi Wen, Webb, Thomas M., Self, Tim J., Feng, Yungfeng, Lagos, Dimitrios, Chu, Chia-Ying, Rana, Tariq M., Morley, Simon J., Longmore, Gregory D., Bushell, Martin, Sharp, Tyson V.
Published in Proceedings of the National Academy of Sciences - PNAS (13.07.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (13.07.2010)
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Journal Article
Extended lifespan of bronchial epithelial cells maintains normal cellular phenotype and transcriptome integrity
O'Loughlin, Jonathan, Hall, Robert J, Bhaker, Sangita, Portelli, Michael A, Henry, Amanda, Pang, Vincent, Bates, David O, Sharp, Tyson V, Sayers, Ian
Published in ERJ open research (01.01.2021)
Published in ERJ open research (01.01.2021)
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Journal Article
SUMOylation is required for optimal TRAF3 signaling capacity
Miliara, Sophia, Gkouskou, Kalliopi K, Sharp, Tyson V, Eliopoulos, Aristides G
Published in PloS one (18.11.2013)
Published in PloS one (18.11.2013)
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Journal Article
chromosome 3p21.3-encoded gene, LIMD1, is a critical tumor suppressor involved in human lung cancer development
Sharp, Tyson V, Al-Attar, Ahmad, Foxler, Daniel E, Ding, Li, de A. Vallim, Thomas Q, Zhang, Yining, Nijmeh, Hala S, Webb, Thomas M, Nicholson, Andrew G, Zhang, Qunyuan, Kraja, Aldi, Spendlove, Ian, Osborne, John, Mardis, Elaine, Longmore, Gregory D
Published in Proceedings of the National Academy of Sciences - PNAS (16.12.2008)
Published in Proceedings of the National Academy of Sciences - PNAS (16.12.2008)
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Journal Article
Ajmaline blocks I Na and I Kr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters
Miller, Duncan C, Harmer, Stephen C, Poliandri, Ariel, Nobles, Muriel, Edwards, Elizabeth C, Ware, James S, Sharp, Tyson V, McKay, Tristan R, Dunkel, Leo, Lambiase, Pier D, Tinker, Andrew
Published in Stem cell research (01.12.2017)
Published in Stem cell research (01.12.2017)
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Journal Article
K15 Protein of Kaposi’s Sarcoma-Associated Herpesvirus Is Latently Expressed and Binds to HAX-1, a Protein with Antiapoptotic Function
Sharp, Tyson V, Wang, Hsei-Wei, Koumi, Andrew, Hollyman, Daniel, Endo, Yoshio, Ye, Hongtao, Du, Ming-Qing, Boshoff, Chris
Published in Journal of Virology (01.01.2002)
Published in Journal of Virology (01.01.2002)
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Journal Article
LIM Domains-Containing Protein 1 (LIMD1), a Tumor Suppressor Encoded at Chromosome 3p21.3, Binds pRB and Represses E2F-Driven Transcription
Sharp, Tyson V., Munoz, Fernando, Bourboulia, Dimitra, Presneau, Nadege, Darai, Eva, Wang, Hsei-Wei, Cannon, Mark, Butcher, David N., Nicholson, Andrew G., Klein, George, Imreh, Stephan, Boshoff, Chris
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2004)
Published in Proceedings of the National Academy of Sciences - PNAS (23.11.2004)
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Journal Article
Suppression of AGO2 by miR-132 as a determinant of miRNA-mediated silencing in human primary endothelial cells
Leonov, German, Shah, Kunal, Yee, Daniel, Timmis, Jon, Sharp, Tyson V., Lagos, Dimitris
Published in The international journal of biochemistry & cell biology (01.12.2015)
Published in The international journal of biochemistry & cell biology (01.12.2015)
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Journal Article
Deregulation of LIMD1-VHL-HIF-1α-VEGF pathway is associated with different stages of cervical cancer
Chakraborty, Chandraditya, Mitra, Sraboni, Roychowdhury, Anirban, Samadder, Sudip, Dutta, Sankhadeep, Roy, Anup, Das, Pradip, Mandal, Ranajit Kumar, Sharp, Tyson V, Roychoudhury, Susanta, Panda, Chinmay Kumar
Published in Biochemical journal (31.05.2018)
Published in Biochemical journal (31.05.2018)
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Journal Article
CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma
Feber, Andrew, Worth, Daniel C, Chakravarthy, Ankur, de Winter, Patricia, Shah, Kunal, Arya, Manit, Saqib, Muhammad, Nigam, Raj, Malone, Peter R, Tan, Wei Shen, Rodney, Simon, Freeman, Alex, Jameson, Charles, Wilson, Gareth A, Powles, Tom, Beck, Stephan, Fenton, Tim, Sharp, Tyson V, Muneer, Asif, Kelly, John D
Published in Cancer research (Chicago, Ill.) (15.08.2016)
Published in Cancer research (Chicago, Ill.) (15.08.2016)
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Journal Article
miR‐132 suppresses transcription of ribosomal proteins to promote protective Th1 immunity
Hewitson, James P, Shah, Kunal M, Brown, Najmeeyah, Grevitt, Paul, Hain, Sofia, Newling, Katherine, Sharp, Tyson V, Kaye, Paul M, Lagos, Dimitris
Published in EMBO reports (01.04.2019)
Published in EMBO reports (01.04.2019)
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Journal Article
BMI-1 extends proliferative potential of human bronchial epithelial cells while retaining their mucociliary differentiation capacity
Munye, Mustafa M, Shoemark, Amelia, Hirst, Robert A, Delhove, Juliette M, Sharp, Tyson V, McKay, Tristan R, O'Callaghan, Christopher, Baines, Deborah L, Howe, Steven J, Hart, Stephen L
Published in American journal of physiology. Lung cellular and molecular physiology (01.02.2017)
Published in American journal of physiology. Lung cellular and molecular physiology (01.02.2017)
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Journal Article