Uncovering disease-disease relationships through the incomplete interactome
Menche, Jörg, Sharma, Amitabh, Kitsak, Maksim, Ghiassian, Susan Dina, Vidal, Marc, Loscalzo, Joseph, Barabási, Albert-László
Published in Science (American Association for the Advancement of Science) (20.02.2015)
Published in Science (American Association for the Advancement of Science) (20.02.2015)
Get full text
Journal Article
Network Medicine in the Age of Biomedical Big Data
Sonawane, Abhijeet R, Weiss, Scott T, Glass, Kimberly, Sharma, Amitabh
Published in Frontiers in genetics (11.04.2019)
Published in Frontiers in genetics (11.04.2019)
Get full text
Journal Article
Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets
Vinayagam, Arunachalam, Gibson, Travis E., Lee, Ho-Joon, Yilmazel, Bahar, Roesel, Charles, Hu, Yanhui, Kwon, Young, Sharma, Amitabh, Liu, Yang-Yu, Perrimon, Norbert, Barabási, Albert-László
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (03.05.2016)
Get full text
Journal Article
Robustness and lethality in multilayer biological molecular networks
Liu, Xueming, Maiorino, Enrico, Halu, Arda, Glass, Kimberly, Prasad, Rashmi B, Loscalzo, Joseph, Gao, Jianxi, Sharma, Amitabh
Published in Nature communications (27.11.2020)
Published in Nature communications (27.11.2020)
Get full text
Journal Article
PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation
Iwata, Hiroshi, Goettsch, Claudia, Sharma, Amitabh, Ricchiuto, Piero, Goh, Wilson Wen Bin, Halu, Arda, Yamada, Iwao, Yoshida, Hideo, Hara, Takuya, Wei, Mei, Inoue, Noriyuki, Fukuda, Daiju, Mojcher, Alexander, Mattson, Peter C, Barabási, Albert-László, Boothby, Mark, Aikawa, Elena, Singh, Sasha A, Aikawa, Masanori
Published in Nature communications (31.10.2016)
Published in Nature communications (31.10.2016)
Get full text
Journal Article
Spatiotemporal Multi-Omics Mapping Generates a Molecular Atlas of the Aortic Valve and Reveals Networks Driving Disease
Schlotter, Florian, Halu, Arda, Goto, Shinji, Blaser, Mark C, Body, Simon C, Lee, Lang H, Higashi, Hideyuki, DeLaughter, Daniel M, Hutcheson, Joshua D, Vyas, Payal, Pham, Tan, Rogers, Maximillian A, Sharma, Amitabh, Seidman, Christine E, Loscalzo, Joseph, Seidman, Jonathan G, Aikawa, Masanori, Singh, Sasha A, Aikawa, Elena
Published in Circulation (New York, N.Y.) (24.07.2018)
Published in Circulation (New York, N.Y.) (24.07.2018)
Get full text
Journal Article
Tissue Specificity of Human Disease Module
Kitsak, Maksim, Sharma, Amitabh, Menche, Jörg, Guney, Emre, Ghiassian, Susan Dina, Loscalzo, Joseph, Barabási, Albert-László
Published in Scientific reports (17.10.2016)
Published in Scientific reports (17.10.2016)
Get full text
Journal Article
Early pregnancy vitamin D status and risk of preeclampsia
Mirzakhani, Hooman, Litonjua, Augusto A, McElrath, Thomas F, O'Connor, George, Lee-Parritz, Aviva, Iverson, Ronald, Macones, George, Strunk, Robert C, Bacharier, Leonard B, Zeiger, Robert, Hollis, Bruce W, Handy, Diane E, Sharma, Amitabh, Laranjo, Nancy, Carey, Vincent, Qiu, Weilliang, Santolini, Marc, Liu, Shikang, Chhabra, Divya, Enquobahrie, Daniel A, Williams, Michelle A, Loscalzo, Joseph, Weiss, Scott T
Published in The Journal of clinical investigation (01.12.2016)
Published in The Journal of clinical investigation (01.12.2016)
Get full text
Journal Article
A multilocus genetic risk score for coronary heart disease: case-control and prospective cohort analyses
Ripatti, Samuli, Dr, Tikkanen, Emmi, MSc, Orho-Melander, Marju, Prof, Havulinna, Aki S, MSc, Silander, Kaisa, PhD, Sharma, Amitabh, PhD, Guiducci, Candace, BS, Perola, Markus, Prof, Jula, Antti, MD, Sinisalo, Juha, MD, Lokki, Marja-Liisa, PhD, Nieminen, Markku S, Prof, Melander, Olle, MD, Salomaa, Veikko, Prof, Peltonen, Leena, Prof, Kathiresan, Sekar, MD
Published in The Lancet (British edition) (23.10.2010)
Published in The Lancet (British edition) (23.10.2010)
Get full text
Journal Article
A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma
Sharma, Amitabh, Menche, Jörg, Huang, C Chris, Ort, Tatiana, Zhou, Xiaobo, Kitsak, Maksim, Sahni, Nidhi, Thibault, Derek, Voung, Linh, Guo, Feng, Ghiassian, Susan Dina, Gulbahce, Natali, Baribaud, Frédéric, Tocker, Joel, Dobrin, Radu, Barnathan, Elliot, Liu, Hao, Panettieri, Jr, Reynold A, Tantisira, Kelan G, Qiu, Weiliang, Raby, Benjamin A, Silverman, Edwin K, Vidal, Marc, Weiss, Scott T, Barabási, Albert-László
Published in Human molecular genetics (01.06.2015)
Published in Human molecular genetics (01.06.2015)
Get full text
Journal Article
Discovering the genes mediating the interactions between chronic respiratory diseases in the human interactome
Maiorino, Enrico, Baek, Seung Han, Guo, Feng, Zhou, Xiaobo, Kothari, Parul H, Silverman, Edwin K, Barabási, Albert-László, Weiss, Scott T, Raby, Benjamin A, Sharma, Amitabh
Published in Nature communications (10.02.2020)
Published in Nature communications (10.02.2020)
Get full text
Journal Article
Protein interaction networks provide insight into fetal origins of chronic obstructive pulmonary disease
Röhl, Annika, Baek, Seung Han, Kachroo, Priyadarshini, Morrow, Jarrett D, Tantisira, Kelan, Silverman, Edwin K, Weiss, Scott T, Sharma, Amitabh, Glass, Kimberly, DeMeo, Dawn L
Published in Respiratory research (24.03.2022)
Published in Respiratory research (24.03.2022)
Get full text
Journal Article
Endophenotype Network Models: Common Core of Complex Diseases
Ghiassian, Susan Dina, Menche, Jörg, Chasman, Daniel I, Giulianini, Franco, Wang, Ruisheng, Ricchiuto, Piero, Aikawa, Masanori, Iwata, Hiroshi, Müller, Christian, Zeller, Tania, Sharma, Amitabh, Wild, Philipp, Lackner, Karl, Singh, Sasha, Ridker, Paul M, Blankenberg, Stefan, Barabási, Albert-László, Loscalzo, Joseph
Published in Scientific reports (09.06.2016)
Published in Scientific reports (09.06.2016)
Get full text
Journal Article
Mechanical forces induce an asthma gene signature in healthy airway epithelial cells
Kılıç, Ayşe, Ameli, Asher, Park, Jin-Ah, Kho, Alvin T, Tantisira, Kelan, Santolini, Marc, Cheng, Feixiong, Mitchel, Jennifer A, McGill, Maureen, O'Sullivan, Michael J, De Marzio, Margherita, Sharma, Amitabh, Randell, Scott H, Drazen, Jeffrey M, Fredberg, Jeffrey J, Weiss, Scott T
Published in Scientific reports (22.01.2020)
Published in Scientific reports (22.01.2020)
Get full text
Journal Article
Author Correction: Discovering the genes mediating the interactions between chronic respiratory diseases in the human interactome
Maiorino, Enrico, Baek, Seung Han, Guo, Feng, Zhou, Xiaobo, Kothari, Parul H, Silverman, Edwin K, Barabási, Albert-László, Weiss, Scott T, Raby, Benjamin A, Sharma, Amitabh
Published in Nature communications (19.04.2021)
Published in Nature communications (19.04.2021)
Get full text
Journal Article
A Systems Approach to Refine Disease Taxonomy by Integrating Phenotypic and Molecular Networks
Zhou, Xuezhong, Lei, Lei, Liu, Jun, Halu, Arda, Zhang, Yingying, Li, Bing, Guo, Zhili, Liu, Guangming, Sun, Changkai, Loscalzo, Joseph, Sharma, Amitabh, Wang, Zhong
Published in EBioMedicine (01.05.2018)
Published in EBioMedicine (01.05.2018)
Get full text
Journal Article
Context-enriched interactome powered by proteomics helps the identification of novel regulators of macrophage activation
Halu, Arda, Wang, Jian-Guo, Iwata, Hiroshi, Mojcher, Alexander, Abib, Ana Luisa, Singh, Sasha A, Aikawa, Masanori, Sharma, Amitabh
Published in eLife (10.10.2018)
Published in eLife (10.10.2018)
Get full text
Journal Article
Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling
Nakano, Toshiaki, Katsuki, Shunsuke, Chen, Mingxian, Decano, Julius L, Halu, Arda, Lee, Lang Ho, Pestana, Diego V S, Kum, Angelo S T, Kuromoto, Rodrigo K, Golden, Whitney S, Boff, Mario S, Guimaraes, Gabriel C, Higashi, Hideyuki, Kauffman, Kevin J, Maejima, Takashi, Suzuki, Takehiro, Iwata, Hiroshi, Barabási, Albert-László, Aster, Jon C, Anderson, Daniel G, Sharma, Amitabh, Singh, Sasha A, Aikawa, Elena, Aikawa, Masanori
Published in Circulation (New York, N.Y.) (02.01.2019)
Published in Circulation (New York, N.Y.) (02.01.2019)
Get full text
Journal Article
Mining literature for a comprehensive pathway analysis: a case study for retrieval of homocysteine related genes for genetic and epigenetic studies
Sharma, Priyanka, Senthilkumar, R D, Brahmachari, Vani, Sundaramoorthy, Elayanambi, Mahajan, Anubha, Sharma, Amitabh, Sengupta, Shantanu
Published in Lipids in health and disease (23.01.2006)
Published in Lipids in health and disease (23.01.2006)
Get full text
Journal Article